Lista de obras -

3-Vinylazetidin-2-Ones: Synthesis, Antiproliferative and Tubulin Destabilizing Activity in MCF-7 and MDA-MB-231 Breast Cancer Cells

artículo científico publicado en 2019

Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells

artículo científico publicado en 2016

Aromatic bis-N-hydroxyguanidinium derivatives: synthesis, biophysical, and biochemical evaluations.

artículo científico publicado en 2013

Development of novel cyclic peptides as pro-apoptotic agents

artículo científico publicado en 2016

Dual targeting of tumour cells and host endothelial cells by novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines.

artículo científico publicado en 2010

Inhibition of γ-secretase activity synergistically enhances tumour necrosis factor-related apoptosis-inducing ligand induced apoptosis in T-cell acute lymphoblastic leukemia cells via upregulation of death receptor 5

artículo científico publicado en 2016

Involvement of NF-κB in mediating the anti-tumour effects of combretastatins in T cells

artículo científico publicado en 2018

Isouronium and N-hydroxyguanidinium derivatives as Cell growth inhibitors: A comparative study.

artículo científico publicado en 2016

Non-nucleoside inhibitors of human adenosine kinase: synthesis, molecular modeling, and biological studies.

artículo científico publicado en 2011

Novel cis-restricted β-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro.

artículo científico publicado en 2012

Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce apoptosis in multi-drug-resistant cancer cells

artículo científico publicado en 2009

Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce cell cycle arrest and apoptosis in prostate cancer cells ⬇️

artículo científico publicado el 1 de diciembre de 2010

PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines.

artículo científico publicado en 2013

Piperlongumine (piplartine) and analogues: Antiproliferative microtubule-destabilising agents.

artículo científico publicado en 2016

Retraction notice to “PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines” [Eur. J. Pharmacol. 714(1–3) (2013) 379–387]

artículo científico publicado en 2014

Synthesis and Biochemical Evaluation of 3-Phenoxy-1,4-diarylazetidin-2-ones as Tubulin-Targeting Antitumor Agents.

artículo científico publicado en 2015

Synthesis and evaluation of antiproliferative microtubule-destabilising combretastatin A-4 piperazine conjugates

scientific article published on 01 June 2019

Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agents.

artículo científico publicado en 2010

The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL‑induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells

artículo científico publicado en 2016

The vascular targeting agent combretastatin-A4 and a novel cis-Restricted {beta}-Lactam Analogue, CA-432, induce apoptosis in human chronic myeloid leukemia cells and ex vivo patient samples including those displaying multidrug resistance.

artículo científico publicado en 2010

β-Lactam analogues of combretastatin A-4 prevent metabolic inactivation by glucuronidation in chemoresistant HT-29 colon cancer cells.

artículo científico publicado en 2017

β-Lactam estrogen receptor antagonists and a dual-targeting estrogen receptor/tubulin ligand.

artículo científico publicado en 2014

β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells

scientific article published on 10 January 2020

Lista de obras de

3-Vinylazetidin-2-Ones: Synthesis, Antiproliferative and Tubulin Destabilizing Activity in MCF-7 and MDA-MB-231 Breast Cancer Cells

Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells

Aromatic bis-N-hydroxyguanidinium derivatives: synthesis, biophysical, and biochemical evaluations.

Development of novel cyclic peptides as pro-apoptotic agents

Dual targeting of tumour cells and host endothelial cells by novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines.

Inhibition of γ-secretase activity synergistically enhances tumour necrosis factor-related apoptosis-inducing ligand induced apoptosis in T-cell acute lymphoblastic leukemia cells via upregulation of death receptor 5

Involvement of NF-κB in mediating the anti-tumour effects of combretastatins in T cells

Isouronium and N-hydroxyguanidinium derivatives as Cell growth inhibitors: A comparative study.

Non-nucleoside inhibitors of human adenosine kinase: synthesis, molecular modeling, and biological studies.

Novel cis-restricted β-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro.

Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce apoptosis in multi-drug-resistant cancer cells

Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce cell cycle arrest and apoptosis in prostate cancer cells ⬇️

PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines.

Piperlongumine (piplartine) and analogues: Antiproliferative microtubule-destabilising agents.

Retraction notice to “PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines” [Eur. J. Pharmacol. 714(1–3) (2013) 379–387]

Synthesis and Biochemical Evaluation of 3-Phenoxy-1,4-diarylazetidin-2-ones as Tubulin-Targeting Antitumor Agents.

Synthesis and evaluation of antiproliferative microtubule-destabilising combretastatin A-4 piperazine conjugates

Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agents.

The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL‑induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells

The vascular targeting agent combretastatin-A4 and a novel cis-Restricted {beta}-Lactam Analogue, CA-432, induce apoptosis in human chronic myeloid leukemia cells and ex vivo patient samples including those displaying multidrug resistance.

β-Lactam analogues of combretastatin A-4 prevent metabolic inactivation by glucuronidation in chemoresistant HT-29 colon cancer cells.

β-Lactam estrogen receptor antagonists and a dual-targeting estrogen receptor/tubulin ligand.

β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells