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A promising approach for treatment of tumor-induced bone diseases: utilizing bisphosphonate derivatives of nucleoside antimetabolites

artículo científico publicado en 2010

A rare case of selective Igκ chain deficiency: Biologic and clinical implications

scientific article published on 03 April 2020

A recombinant IL-4-Pseudomonas exotoxin inhibits protein synthesis and overcomes apoptosis resistance in human CLL B cells.

artículo científico publicado en 2005

A role for BLyS in the activation of innate immune cells

artículo científico publicado en 2006

A role for Janus kinases in crosstalk between ErbB3 and the interferon-alpha signaling complex in myeloma cells

artículo científico publicado en 2004

A role for insulin-like growth factor in the regulation of IL-6-responsive human myeloma cell line growth

artículo científico publicado en 1997

A role for phosphatidylinositol 3-kinase in generating T cell help for B cell growth and differentiation

scientific article published on 01 October 1996

A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union

artículo científico publicado en 2014

A-Miz-ing BCL6.

artículo científico publicado en 2005

AML-1A and AML-1B regulation of MIP-1alpha expression in multiple myeloma.

artículo científico publicado en 2003

Aberrant expression of B-lymphocyte stimulator by B chronic lymphocytic leukemia cells: a mechanism for survival

artículo científico publicado en 2002

Acquired chromosomal anomalies in chronic lymphocytic leukemia patients compared with more than 50,000 quasi-normal participants

artículo científico publicado en 2014

Age at diagnosis and the utility of prognostic testing in patients with chronic lymphocytic leukemia

artículo científico publicado en 2010

Akt inhibitor MK-2206 in combination with bendamustine and rituximab in relapsed or refractory chronic lymphocytic leukemia: Results from the N1087 alliance study.

artículo científico publicado en 2017

Alternative splicing regulates activation-induced cytidine deaminase (AID): implications for suppression of AID mutagenic activity in normal and malignant B cells

artículo científico publicado en 2008

Analysis of IL-6-mediated growth control of myeloma cells using a gp130 chimeric receptor approach

artículo científico publicado en 2002

Analysis of clonal B-cell CD38 and immunoglobulin variable region sequence status in relation to clinical outcome for B-chronic lymphocytic leukaemia

artículo científico publicado en 2001

Angiogenesis in B-chronic lymphocytic leukemia

scientific article published on 01 June 2001

Angiogenesis in B-chronic lymphocytic leukemia

artículo científico publicado en 2001

Atypical expression of ErbB3 in myeloma cells: cross-talk between ErbB3 and the interferon-alpha signaling complex

artículo científico publicado en 2003

Autoimmune cytopenia in chronic lymphocytic leukemia/small lymphocytic lymphoma: changes in clinical presentation and prognosis

artículo científico publicado en 2009

B lymphocyte stimulator regulates adaptive immune responses by directly promoting dendritic cell maturation

artículo científico publicado en 2008

B-CLL cells are capable of synthesis and secretion of both pro- and anti-angiogenic molecules

artículo científico publicado en 2002

B-CLL: is the enigma of disease heterogeneity about to be revealed?

artículo científico publicado en 2002

B-cell count and survival: differentiating chronic lymphocytic leukemia from monoclonal B-cell lymphocytosis based on clinical outcome

artículo científico publicado en 2008

BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma

artículo científico publicado en 2014

Biologic and genetic characterization of the novel amyloidogenic lambda light chain-secreting human cell lines, ALMC-1 and ALMC-2.

artículo científico publicado en 2008

Biological evaluation of CpG stimulation of normal human B‐cells: implications for B‐cell biology and cytogenetic analysis of CLL B‐cells ⬇️

artículo científico publicado el 17 de febrero de 2011

Bone marrow stromal cells protect lymphoma B-cells from rituximab-induced apoptosis and targeting integrin α-4-β-1 (VLA-4) with natalizumab can overcome this resistance

artículo científico publicado en 2011

Brief report: natural history of individuals with clinically recognized monoclonal B-cell lymphocytosis compared with patients with Rai 0 chronic lymphocytic leukemia

artículo científico publicado en 2009

CD147 regulates the expression of MCT1 and lactate export in multiple myeloma cells

artículo científico publicado en 2013

CD38 expression levels in chronic lymphocytic leukemia B cells are associated with activation marker expression and differential responses to interferon stimulation.

artículo científico publicado en 2005

CD40 expression in malignant plasma cells. Role in stimulation of autocrine IL-6 secretion by a human myeloma cell line.

artículo científico publicado en 1994

CD49d associates with nodal presentation and subsequent development of lymphadenopathy in patients with chronic lymphocytic leukaemia

artículo científico publicado en 2017

CD49d expression is an independent predictor of overall survival in patients with chronic lymphocytic leukaemia: a prognostic parameter with therapeutic potential

artículo científico publicado en 2008

CLL B cells with a bimodal CD38 expression pattern: persistence of bimodal populations despite effective therapy for B-CLL ⬇️

artículo científico publicado el 1 de enero de 2004

Cd4+ T-cell immune response to large B-cell non-Hodgkin's lymphoma predicts patient outcome.

artículo científico publicado en 2001

Characterization and use of the novel human multiple myeloma cell line MC-B11/14 to study biological consequences of CRISPR-mediated loss of immunoglobulin A heavy chain

artículo científico publicado en 2017

Chromosome anomalies detected by interphase fluorescence in situ hybridization: correlation with significant biological features of B-cell chronic lymphocytic leukaemia

scientific article published on 01 April 2003

Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes

artículo científico publicado en 2017

Chronic lymphocytic leukemia

artículo científico publicado en 2002

Chronic lymphocytic leukemia in young (≤ 55 years) patients: a comprehensive analysis of prognostic factors and outcomes

artículo científico publicado en 2013

Clinical Course and Prognosis of Smoldering (Asymptomatic) Multiple Myeloma

article

Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study

artículo científico publicado en 2014

Clonotypic Light Chain Peptides Identified for Monitoring Minimal Residual Disease in Multiple Myeloma without Bone Marrow Aspiration

scientific article published on October 2015

Coexistence of aneuploid subclones within a myeloma cell line that exhibits clonal immunoglobulin gene rearrangement: clinical implications

artículo científico publicado en 1993

Combination chemoimmunotherapy with pentostatin, cyclophosphamide, and rituximab shows significant clinical activity with low accompanying toxicity in previously untreated B chronic lymphocytic leukemia

artículo científico publicado en 2007

Comparative activation requirements of human peripheral blood, spleen, and lymph node B cells

scientific article published on 01 August 1987

Comparison of Multiple Myeloma Donor Patient Samples and Derived Cell Lines Identifies a Confirmed Hyperdiploid Myeloma Cell Line and Demonstrates Remarkable Genetic Similarity Between Cell Lines and Patient Samples

artículo científico

Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997.

artículo científico publicado en 2007

Comprehensive assessment of potential multiple myeloma immunoglobulin heavy chain V-D-J intraclonal variation using massively parallel pyrosequencing

artículo científico publicado en 2012

Cytogenetic abnormalities can change during the course of the disease process in chronic lymphocytic leukemia

artículo científico publicado en 2006

Cytogenetic prioritization with inclusion of molecular markers predicts outcome in previously untreated patients with chronic lymphocytic leukemia treated with fludarabine or fludarabine plus cyclophosphamide: a long-term follow-up study of the US i

artículo científico publicado en 2015

Delineation of the functional capacity of human neonatal lymphocytes ⬇️

artículo científico publicado el 1 de febrero de 1991

Development of a cell with dendritic morphology from a precursor of B lymphocyte lineage

artículo científico publicado en 1987

Differential human multiple myeloma cell line responsiveness to interferon-alpha. Analysis of transcription factor activation and interleukin 6 receptor expression

artículo científico publicado en 1997

Differentiation of chronic lymphocytic leukemia B cells into immunoglobulin secreting cells decreases LEF-1 expression

artículo científico publicado en 2011

Direct and complement dependent cytotoxicity in CLL cells from patients with high-risk early-intermediate stage chronic lymphocytic leukemia (CLL) treated with alemtuzumab and rituximab

artículo científico publicado en 2008

Dissociation between IFN-alpha-induced anti-viral and growth signaling pathways

artículo científico publicado en 1999

Divergent effects of BAFF on human memory B cell differentiation into Ig-secreting cells.

artículo científico publicado en 2007

Early treatment of high-risk chronic lymphocytic leukemia with alemtuzumab and rituximab

artículo científico publicado en 2008

Effects of Interferon Alpha on Myeloma Cells: Mechanisms of Differential Responsiveness ⬇️

artículo científico publicado el 1 de enero de 1997

Elevated serum B-lymphocyte stimulator levels in patients with familial lymphoproliferative disorders.

artículo científico publicado en 2006

Enhancement of human B cell proliferation and differentiation by tumor necrosis factor-alpha and interleukin 1

scientific article published on 01 November 1987

Eosinophil purification from human bone marrow

scientific article published on 01 January 2014

Eosinophils regulate peripheral B cell numbers in both mice and humans

artículo científico publicado en 2014

Establishment and characterization of three myeloma cell lines that demonstrate variable cytokine responses and abilities to produce autocrine interleukin-6.

artículo científico publicado en 1996

Evidence for ongoing DNA damage in multiple myeloma cells as revealed by constitutive phosphorylation of H2AX

artículo científico publicado en 2011

Evolutionary dynamics of two related malignant plasma cell lines ⬇️

artículo científico publicado el 15 de septiembre de 2010

Expression and function of Fas (APO-1/CD95) in patient myeloma cells and myeloma cell lines.

artículo científico publicado en 1995

Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival ⬇️

artículo científico publicado el 25 de septiembre de 2003

Expression of BLyS and its receptors in B-cell non-Hodgkin lymphoma: correlation with disease activity and patient outcome.

artículo científico publicado en 2004

Expression of TCL-1 as a potential prognostic factor for treatment outcome in B-cell chronic lymphocytic leukemia

artículo científico publicado en 2007

Fluorescent-labeled DNA probes applied to novel biological aspects of B-cell chronic lymphocytic leukemia

artículo científico publicado en 2005

Gene-expression profiling of Waldenstrom macroglobulinemia reveals a phenotype more similar to chronic lymphocytic leukemia than multiple myeloma

artículo científico publicado en 2006

Genetic characterization of SF3B1 mutations in single chronic lymphocytic leukemia cells

artículo científico publicado en 2013

Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma

artículo científico publicado en 2007

Growth regulatory pathways in myeloma. Evidence for autocrine oncostatin M expression.

artículo científico publicado en 1996

Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL

artículo científico publicado en 2020

Human B lymphocyte malignancies: exploitation of BLyS and APRIL and their receptors

artículo científico publicado en 2005

Human peripheral blood B lymphocyte subpopulations: functional and phenotypic analysis of surface IgD positive and negative subsets

artículo científico publicado en 1986

Hypogammaglobulinemia in newly diagnosed chronic lymphocytic leukemia: Natural history, clinical correlates, and outcomes

artículo científico publicado en 2015

IL-3 expression by myeloma cells increases both osteoclast formation and growth of myeloma cells

artículo científico publicado en 2003

Ibrutinib-Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia

artículo científico publicado en 2019

Identification of a global gene expression signature of B-chronic lymphocytic leukemia.

artículo científico publicado en 2003

Immunogenetics shows that not all MBL are equal: the larger the clone, the more similar to CLL.

artículo científico publicado en 2013

Immunoglobulin diversity gene usage predicts unfavorable outcome in a subset of chronic lymphocytic leukemia patients

artículo científico publicado en 2008

Immunoglobulin free light chain ratio is an independent risk factor for progression of smoldering (asymptomatic) multiple myeloma

artículo científico publicado en 2008

Immunoglobulin heavy variable (IGHV) genes and alleles: new entities, new names and implications for research and prognostication in chronic lymphocytic leukaemia

artículo científico publicado en 2014

Immunomodulatory role of IL-4 on the secretion of Ig by human B cells

scientific article published on 01 March 1989

In vitro autoantibody production by normal adult and cord blood B cells

artículo científico publicado en 1990

Increased expression of extracellular matrix metalloproteinase inducer (CD147) in multiple myeloma: role in regulation of myeloma cell proliferation

artículo científico publicado en 2012

Increased signaling through p62 in the marrow microenvironment increases myeloma cell growth and osteoclast formation

artículo científico publicado en 2009

Induction of malignant plasma cell proliferation by eosinophils

artículo científico publicado en 2013

Infection and killing of multiple myeloma by adenoviruses

artículo científico publicado en 2010

Infectious complications among individuals with clinical monoclonal B-cell lymphocytosis (MBL): a cohort study of newly diagnosed cases compared to controls

artículo científico publicado en 2012

Inhibition of human B cell responsiveness by prostaglandin E2

scientific article published on 01 February 1987

Inhibition of survivin expression suppresses the growth of aggressive non-Hodgkin's lymphoma

artículo científico publicado en 2004

Inhibitory influence of IL-4 on human B cell responsiveness

scientific article published on 01 July 1988

Interleukin 6 induces monocyte chemoattractant protein-1 expression in myeloma cells

artículo científico publicado en 2002

Karyotype evolution on fluorescent in situ hybridization analysis is associated with short survival in patients with chronic lymphocytic leukemia and is related to CD49d expression

artículo científico publicado en 2008

LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis

artículo científico publicado en 2010

Long-term repair of T-cell synapse activity in a phase II trial of chemoimmunotherapy followed by lenalidomide consolidation in previously untreated chronic lymphocytic leukemia (CLL).

artículo científico publicado en 2013

Longitudinal genome-wide analysis of patients with chronic lymphocytic leukemia reveals complex evolution of clonal architecture at disease progression and at the time of relapse.

artículo científico publicado en 2012

MBL or CLL: which classification best categorizes the clinical course of patients with an absolute lymphocyte count >or= 5 x 10(9) L(-1) but a B-cell lymphocyte count <5 x 10(9) L(-1)?

artículo científico publicado en 2008

MIP-1alpha utilizes both CCR1 and CCR5 to induce osteoclast formation and increase adhesion of myeloma cells to marrow stromal cells.

artículo científico publicado en 2005

Mcl-1 expression predicts progression-free survival in chronic lymphocytic leukemia patients treated with pentostatin, cyclophosphamide, and rituximab

artículo científico publicado en 2008

Methylprednisolone-rituximab is an effective salvage therapy for patients with relapsed chronic lymphocytic leukemia including those with unfavorable cytogenetic features

artículo científico publicado en 2007

Molecular analysis of immunoglobulin genes reveals frequent clonal relatedness in double monoclonal gammopathies

artículo científico publicado en 2013

Molecular and biological role of CD40 in multiple myeloma

scientific article published on 01 January 1995

Monitoring M-Proteins in Patients with Multiple Myeloma Using Heavy-Chain Variable Region Clonotypic Peptides and LC–MS/MS

artículo científico publicado en 2014

Multiple myeloma dell-derived microvesicles are enriched in CD147 expression and enhance tumor cell proliferation

artículo científico publicado en 2014

Multiplex Immunofluorescence of Bone Marrow Core Biopsies: Visualizing the Bone Marrow Immune Contexture

artículo científico publicado en 2019

Myeloma research goes 3D

scientific article published on 01 October 2008

No improvement in long-term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets #1 and #2 treated with chemo(immuno)therapy

artículo científico publicado en 2017

Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations

artículo científico publicado en 2014

Ofatumumab-based chemoimmunotherapy is effective and well tolerated in patients with previously untreated chronic lymphocytic leukemia (CLL).

artículo científico publicado en 2013

Pentostatin and rituximab therapy for previously untreated patients with B-cell chronic lymphocytic leukemia

artículo científico publicado en 2010

Percentage of smudge cells on routine blood smear predicts survival in chronic lymphocytic leukemia

artículo científico publicado en 2009

Phase 1 study of interleukin-12 in combination with rituximab in patients with B-cell non-Hodgkin lymphoma

artículo científico publicado en 2002

Phase 2 trial of daily, oral Polyphenon E in patients with asymptomatic, Rai stage 0 to II chronic lymphocytic leukemia

artículo científico publicado en 2012

Phase I trial of daily oral Polyphenon E in patients with asymptomatic Rai stage 0 to II chronic lymphocytic leukemia

artículo científico publicado en 2009

Phase II trials of single-agent anti-VEGF therapy for patients with chronic lymphocytic leukemia ⬇️

artículo científico publicado el 5 de noviembre de 2010

Phenotyping polyclonal kappa and lambda light chain molecular mass distributions in patient serum using mass spectrometry

artículo científico publicado en 2014

Phosphatidylinositol 3-kinase activation in normal human B lymphocytes

artículo científico publicado en 1996

Platelet-derived growth factor (PDGF)-PDGF receptor interaction activates bone marrow-derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: implications for an angiogenic switch

artículo científico publicado en 2010

Prevalence and risk of progression of light-chain monoclonal gammopathy of undetermined significance: a retrospective population-based cohort study

artículo científico publicado en 2010

Prognostic importance of T and NK-cells in a consecutive series of newly diagnosed patients with chronic lymphocytic leukaemia

scientific article published on April 2008

Progressive but previously untreated CLL patients with greater array CGH complexity exhibit a less durable response to chemoimmunotherapy

artículo científico publicado en 2010

Prospective evaluation of clonal evolution during long-term follow-up of patients with untreated early-stage chronic lymphocytic leukemia.

artículo científico publicado en 2006

Protein expression profiling of CLL B cells using replicate off-line strong cation exchange chromatography and LC-MS/MS

artículo científico publicado en 2005

Proteomic detection of immunoglobulin light chain variable region peptides from amyloidosis patient biopsies

artículo científico publicado en 2015

Purification of functional eosinophils from human bone marrow

artículo científico publicado en 2012

Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia

artículo científico publicado en 2012

Quantitative protein expression analysis of CLL B cells from mutated and unmutated IgV(H) subgroups using acid-cleavable isotope-coded affinity tag reagents

artículo científico publicado en 2005

Regulated expression of BAFF-binding receptors during human B cell differentiation.

artículo científico publicado en 2007

Regulation of human B cell activation by prostaglandin E2. Suppression of the generation of immunoglobulin-secreting cells

artículo científico publicado en 1985

Regulation of human B cell proliferation by prostaglandin E2

artículo científico publicado en 1984

Regulation of human B lymphocyte activation, proliferation, and differentiation

artículo científico publicado en 1987

Regulation of human B lymphocyte responsiveness

artículo científico publicado en 1988

Responsiveness of cytogenetically discrete human myeloma cell lines to lenalidomide: lack of correlation with cereblon and interferon regulatory factor 4 expression levels

artículo científico publicado en 2013

Risk factors for development of a second lymphoid malignancy in patients with chronic lymphocytic leukaemia

artículo científico publicado en 2007

Role of long non-coding RNAs in disease progression of early stage unmutated chronic lymphocytic leukemia

Selective induction of DNA repair pathways in human B cells activated by CD4+ T cells

artículo científico publicado en 2010

Selective inhibition of inflammatory gene expression in activated T lymphocytes: a mechanism of immune suppression by thiopurines

artículo científico publicado en 2004

Sequence, expression and function of an mRNA encoding a soluble form of the human interleukin-6 receptor (sIL-6R).

artículo científico publicado en 1995

Sharpening spots: correcting for bleedover in cDNA array images.

artículo científico publicado en 2002

Species D adenoviruses as oncolytics against B-cell cancers

artículo científico publicado en 2011

Survival of patients with clinically identified monoclonal B-cell lymphocytosis (MBL) relative to the age- and sex-matched general population

scientific article published on 12 August 2011

T cell-dependent activation of B cell proliferation and differentiation by immobilized monoclonal antibodies to CD3

artículo científico publicado en 1988

TALEN-mediated genetic tailoring as a tool to analyze the function of acquired mutations in multiple myeloma cells

artículo científico publicado en 2014

The histone methyltransferase MMSET regulates class switch recombination

scientific journal article

The oncogenic transcription factor IRF4 is regulated by a novel CD30/NF-κB positive feedback loop in peripheral T-cell lymphoma

artículo científico publicado en 2015

The prognostic significance of cytopenia in chronic lymphocytic leukaemia/small lymphocytic lymphoma

artículo científico publicado en 2008

The role of B cell proliferation in the generation of immunoglobulin-secreting cells in man ⬇️

artículo científico publicado el 1 de junio de 1983

The roles of T cell factors in activation, cell cycle progression, and differentiation of human B cells

artículo científico publicado en 1985

The roles of interleukin 2 and interferon-gamma in human B cell activation, growth and differentiation

artículo científico publicado en 1986

The structure of the TNFRSF13C promoter enables differential expression of BAFF-R during B cell ontogeny and terminal differentiation.

artículo científico publicado en 2010

Transactivation of gp130 in myeloma cells

artículo científico publicado en 2003

Transcriptional and post-transcriptional mechanisms of BAFF-receptor dysregulation in human B lineage malignancies

artículo científico publicado en 2010

Uncovering the biology of multiple myeloma among African Americans: a comprehensive genomics approach

artículo científico publicado en 2013

Using smudge cells on routine blood smears to predict clinical outcome in chronic lymphocytic leukemia: a universally available prognostic test

artículo científico publicado en 2007

VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia

artículo científico publicado en 2004

VEGF receptors on chronic lymphocytic leukemia (CLL) B cells interact with STAT 1 and 3: implication for apoptosis resistance

artículo científico publicado en 2005

Validation of a new prognostic index for patients with chronic lymphocytic leukemia

scientific article published on January 2009

ZAP-70 is expressed by a subset of normal human B-lymphocytes displaying an activated phenotype

artículo científico publicado en 2005

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