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A Phase 2, randomized, partially blinded, active-controlled study assessing the efficacy and safety of variable anticoagulation reversal using the REG1 system in patients with acute coronary syndromes: results of the RADAR trial

artículo científico publicado en 2012

A biomarker-based risk score to predict death in patients with atrial fibrillation: the ABC (age, biomarkers, clinical history) death risk score

artículo científico publicado en 2017

A double-blind, randomized, controlled, multicenter study to assess the safety and cardiovascular effects of skeletal myoblast implantation by catheter delivery in patients with chronic heart failure after myocardial infarction

artículo científico publicado en 2011

A randomized, double-blind, placebo-controlled, multicenter study to evaluate the cardioprotective effects of MC-1 in patients undergoing high-risk coronary artery bypass graft surgery: MC-1 to Eliminate Necrosis and Damage in Coronary Artery Bypass

artículo científico publicado en 2008

A randomized, partially blinded, multicenter, active-controlled, dose-ranging study assessing the safety, efficacy, and pharmacodynamics of the REG1 anticoagulation system in patients with acute coronary syndromes: design and rationale of the RADAR

artículo científico publicado en 2011

A systematic assessment of cardiovascular outcomes in the saxagliptin drug development program for type 2 diabetes

artículo científico publicado en 2010

A systematic review of randomized trials comparing double versus triple antithrombotic therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention

scientific article published on 11 November 2019

Advances in antithrombotic therapy in acute myocardial infarction: the ExTRACT-TIMI 25 and OASIS-6 Trials

scientific article published on 01 July 2006

An open-Label, 2 × 2 factorial, randomized controlled trial to evaluate the safety of apixaban vs. vitamin K antagonist and aspirin vs. placebo in patients with atrial fibrillation and acute coronary syndrome and/or percutaneous coronary interventio

artículo científico publicado en 2018

Anemia is associated with bleeding and mortality, but not stroke, in patients with atrial fibrillation: Insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial

artículo científico publicado en 2016

Angiotensin Receptor Blockade Improves Cardiac Surgical Outcomes in Patients With Metabolic Syndrome

artículo científico publicado en 2017

Antiarrhythmic drug therapy for sustained ventricular arrhythmias complicating acute myocardial infarction

artículo científico publicado en 2011

Anticoagulant therapy and outcomes in patients with prior or acute heart failure and acute coronary syndromes: Insights from the APixaban for PRevention of Acute ISchemic Events 2 trial

artículo científico publicado en 2015

Anticoagulation therapy and clinical outcomes in patients with recently diagnosed atrial fibrillation: Insights from the ARISTOTLE trial

artículo científico publicado en 2016

Antithrombotic Strategies in Patients With Atrial Fibrillation and Percutaneous Coronary Intervention-Reply

scientific article published on 07 October 2020

Antithrombotic Therapy Use and Clinical Outcomes Following Thromboembolic Events in Patients with Atrial Fibrillation: Insights from ARISTOTLE.

artículo científico publicado en 2018

Antithrombotic Therapy after Acute Coronary Syndrome or PCI in Atrial Fibrillation

scientific article published on 17 March 2019

Antithrombotic Therapy in Patients With Atrial Fibrillation and Acute Coronary Syndrome Treated Medically or With Percutaneous Coronary Intervention or Undergoing Elective Percutaneous Coronary Intervention: Insights From the AUGUSTUS Trial

scientific article published on 26 September 2019

Antithrombotic therapies in patients with prosthetic heart valves: guidelines translated for the clinician.

artículo científico publicado en 2011

Antithrombotic therapy after acute coronary syndrome and/or percutaneous coronary intervention in atrial fibrillation: finding the sweet spot

artículo científico publicado en 2019

Antithrombotic therapy for atrial fibrillation and coronary artery disease in older patients

artículo científico publicado en 2012

Antithrombotic therapy for ischemic stroke: guidelines translated for the clinician

artículo científico publicado en 2010

Antithrombotic therapy in acute coronary syndromes: guidelines translated for the clinician

artículo científico publicado en 2010

Antithrombotic therapy in atrial fibrillation: guidelines translated for the clinician

artículo científico publicado en 2008

Antithrombotic therapy in heparin-induced thrombocytopenia: guidelines translated for the clinician

artículo científico publicado en 2012

Apixaban 5 mg Twice Daily and Clinical Outcomes in Patients With Atrial Fibrillation and Advanced Age, Low Body Weight, or High Creatinine: A Secondary Analysis of a Randomized Clinical Trial

artículo científico

Apixaban Plus Mono Versus Dual Antiplatelet Therapy in Acute Coronary Syndromes: Insights From the APPRAISE-2 Trial.

artículo científico publicado en 2015

Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of the ARISTOTLE trial

artículo científico publicado en 2012

Apixaban following acute coronary syndromes in patients with prior stroke: Insights from the APPRAISE-2 trial

artículo científico publicado en 2017

Apixaban for reduction in stroke and other ThromboemboLic events in atrial fibrillation (ARISTOTLE) trial: design and rationale

artículo científico publicado en 2010

Apixaban in Comparison With Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease: Findings From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial

artículo científico

Apixaban in patients with atrial fibrillation and prior coronary artery disease: insights from the ARISTOTLE trial

artículo científico publicado en 2013

Apixaban versus Warfarin in Patients with Atrial Fibrillation and Advanced Chronic Kidney Disease

artículo científico publicado en 2020

Apixaban versus warfarin in patients with atrial fibrillation according to prior warfarin use: results from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation trial

artículo científico publicado en 2013

Apixaban vs. warfarin with concomitant aspirin in patients with atrial fibrillation: insights from the ARISTOTLE trial

artículo científico publicado en 2013

Apixaban with antiplatelet therapy after acute coronary syndrome

artículo científico publicado en 2011

Apixaban, an oral, direct, selective factor Xa inhibitor, in combination with antiplatelet therapy after acute coronary syndrome: results of the Apixaban for Prevention of Acute Ischemic and Safety Events (APPRAISE) trial.

artículo científico publicado en 2009

Are We At Risk of Depriving Patients Lifesaving Cardiac Surgery?: Implications of the ISCHEMIA Trial for Coronary Artery Bypass Graft Surgery

artículo científico publicado en 2020

Association Between Delays in Mechanical Ventilation Initiation and Mortality in Patients With Refractory Cardiogenic Shock

scientific article published on 20 May 2020

Association between CK-MB Area Under the Curve and Tranexamic Acid Utilization in Patients Undergoing Coronary Artery Bypass Surgery

artículo científico publicado en 2017

Association between endoscopic vs open vein-graft harvesting and mortality, wound complications, and cardiovascular events in patients undergoing CABG surgery

artículo científico publicado en 2012

Association between levosimendan, postoperative AKI, and mortality in cardiac surgery: Insights from the LEVO-CTS trial

artículo científico publicado en 2020

Association of Different Estimates of Renal Function With Cardiovascular Mortality and Bleeding in Atrial Fibrillation

scientific article published on 31 August 2020

Association of Myocardial Enzyme Elevation and Survival Following Coronary Artery Bypass Graft Surgery ⬇️

artículo científico publicado el 9 de febrero de 2011

Association of height with outcomes in patients with acute myocardial infarction receiving reperfusion therapy

artículo científico publicado en 2005

Asymmetric and Symmetric Dimethylarginine Predict Outcomes in Patients With Atrial Fibrillation: An ARISTOTLE Substudy

artículo científico publicado en 2018

Biomarkers of inflammation and risk of cardiovascular events in anticoagulated patients with atrial fibrillation

artículo científico

Blood Pressure Control and Risk of Stroke or Systemic Embolism in Patients With Atrial Fibrillation: Results From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial

artículo científico publicado en 2015

Cardiac troponin is associated with cardiac outcomes in men and women with atrial fibrillation, insights from the ARISTOTLE trial

scientific article published on 30 April 2020

Characterising and predicting bleeding in high-risk patients with an acute coronary syndrome

artículo científico publicado en 2015

Characteristics and Outcomes of Atrial Fibrillation in Patients With Thyroid Disease (from the ARISTOTLE Trial)

scientific article published on 07 August 2019

Characterization of myocardial infarction as an end point in two large trials of acute coronary syndromes

artículo científico publicado en 2005

Chromogenic laboratory assays to measure the factor Xa-inhibiting properties of apixaban--an oral, direct and selective factor Xa inhibitor

artículo científico publicado en 2011

Claims-based cardiovascular outcome identification for clinical research: Results from 7 large randomized cardiovascular clinical trials

artículo científico publicado en 2019

Clinical Considerations Prior to Transition From Triple Antithrombotic Therapy to Dual Antithrombotic Therapy-Reply

scientific article published on 04 December 2019

Clinical Outcomes and History of Fall in Patients with Atrial Fibrillation Treated with Oral Anticoagulation: Insights From the ARISTOTLE Trial

artículo científico publicado en 2017

Clinical and Pharmacological Effects of Apixaban Dose Adjustment in the ARISTOTLE Trial

artículo científico publicado en 2020

Clinical consequences of bleeding among individuals with a recent acute coronary syndrome: Insights from the APPRAISE-2 trial

artículo científico publicado en 2019

Clinical events after transitioning from apixaban versus warfarin to warfarin at the end of the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial

artículo científico publicado en 2014

Clinical outcomes after hybrid coronary revascularization versus coronary artery bypass surgery: a meta-analysis of 1,190 patients

artículo científico

Clinical outcomes and management associated with major bleeding in patients with atrial fibrillation treated with apixaban or warfarin: insights from the ARISTOTLE trial

artículo científico

Clinical outcomes in patients with atrial fibrillation according to sex during anticoagulation with apixaban or warfarin: a secondary analysis of a randomized controlled trial

artículo científico publicado en 2015

Clinical outcomes of hybrid coronary revascularization versus coronary artery bypass surgery in patients with diabetes mellitus

artículo científico publicado en 2014

Clinical outcomes of patients with diabetes and atrial fibrillation treated with apixaban: results from the ARISTOTLE trial

artículo científico publicado en 2015

Clinical trials evaluating red blood cell transfusion thresholds: An updated systematic review and with additional focus on patients with cardiovascular disease

artículo científico publicado en 2018

Clopidogrel use After Myocardial Revascularization: Prevalence, Predictors, and One-Year Survival Rate

artículo científico publicado en 2016

Combined coagulation phase-directed factor Xa inhibition with heparin compounds and DX-9065a - a direct and selective antagonist

scientific article published on 01 December 2004

Comparison of Outcomes and Frequency of Graft Failure With Use of Free Versus In Situ Internal Mammary Artery Bypass Conduits (from the PREVENT IV Trial)

artículo científico publicado en 2018

Comparison of clinical trial outcome patterns in patients following acute coronary syndromes and in patients with chronic stable atherosclerosis.

artículo científico publicado en 2014

Comparison of incidence of bleeding and mortality of men versus women with ST-elevation myocardial infarction treated with fibrinolysis

artículo científico publicado en 2011

Continuing versus suspending angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: Impact on adverse outcomes in hospitalized patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

scientific article published on 13 May 2020

Coronary artery bypass graft failure after on-pump and off-pump coronary artery bypass: findings from PREVENT IV.

artículo científico publicado en 2008

Coronary-Artery Bypass Grafting

artículo científico publicado en 2016

Coronary-Artery Bypass Grafting.

artículo científico publicado en 2016

Costs associated with health care-associated infections in cardiac surgery

artículo científico publicado en 2015

Creatine kinase-MB elevation after coronary artery bypass grafting surgery in patients with non-ST-segment elevation acute coronary syndromes predict worse outcomes: results from four large clinical trials

artículo científico publicado en 2007

Crowdsourcing consensus: proposal of a novel method for assessing accuracy in echocardiography interpretation

artículo científico publicado en 2018

Dabigatran Compared With Rivaroxaban vs Warfarin

artículo científico publicado en 2017

Dabigatran for periprocedural anticoagulation following radiofrequency ablation for atrial fibrillation: a meta-analysis of observational studies

artículo científico publicado en 2013

Design, rationale, and initiation of the Surgical Interventions for Moderate Ischemic Mitral Regurgitation Trial: a report from the Cardiothoracic Surgical Trials Network

artículo científico publicado en 2011

Development of DX-9065a, a novel direct factor Xa antagonist, in cardiovascular disease.

artículo científico publicado en 2004

Differential occurrence, profile, and impact of first recurrent cardiovascular events after an acute coronary syndrome

artículo científico publicado en 2017

Digoxin and Mortality in Patients With Atrial Fibrillation.

artículo científico publicado en 2018

Direct Oral Anticoagulants in Addition to Antiplatelet Therapy for Secondary Prevention After Acute Coronary Syndromes: A Systematic Review and Meta-analysis.

artículo científico publicado en 2018

Documentation of study medication dispensing in a prospective large randomized clinical trial: experiences from the ARISTOTLE Trial

Dual antiplatelet therapy for perioperative myocardial infarction following CABG surgery

artículo científico publicado en 2018

Dyslipidemia and Risk of Cardiovascular Events in Patients With Atrial Fibrillation Treated With Oral Anticoagulation Therapy: Insights From the ARISTOTLE (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation) Tria

artículo científico publicado en 2018

Echocardiographic Risk Factors for Stroke and Outcomes in Patients With Atrial Fibrillation Anticoagulated With Apixaban or Warfarin

artículo científico publicado en 2017

Economic Analysis of Apixaban Therapy for Patients With Atrial Fibrillation From a US Perspective: Results From the ARISTOTLE Randomized Clinical Trial

artículo científico

Edifoligide and long-term outcomes after coronary artery bypass grafting: PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT IV) 5-year results

artículo científico publicado en 2012

Effect of Apixaban on All-Cause Death in Patients with Atrial Fibrillation: a Meta-Analysis Based on Imputed Placebo Effect

artículo científico publicado en 2017

Effect of Linagliptin vs Placebo on Major Cardiovascular Events in Adults With Type 2 Diabetes and High Cardiovascular and Renal Risk: The CARMELINA Randomized Clinical Trial

scientific article published on 01 January 2019

Effect of apixaban compared with warfarin on coagulation markers in atrial fibrillation

scientific article published on 12 September 2018

Effect of apixaban, an oral and direct factor Xa inhibitor, on coagulation activity biomarkers following acute coronary syndrome ⬇️

artículo científico publicado el 30 de agosto de 2010

Effect of levosimendan on survival and adverse events after cardiac surgery: a meta-analysis

artículo científico publicado en 2013

Effect of nitric oxide synthase inhibition on haemodynamics and outcome of patients with persistent cardiogenic shock complicating acute myocardial infarction: a phase II dose-ranging study

artículo científico publicado en 2007

Effect of tenecteplase versus alteplase on platelets during the first 3 hours of treatment for acute myocardial infarction: the Assessment of the Safety and Efficacy of a New Thrombolytic Agent (ASSENT-2) platelet substudy

artículo científico publicado en 2003

Effect of the REG1 anticoagulation system versus bivalirudin on outcomes after percutaneous coronary intervention (REGULATE-PCI): a randomised clinical trial

artículo científico publicado en 2015

Effect of the novel direct factor Xa inhibitor DX-9065a on thrombin generation and inhibition among patients with stable atherosclerotic coronary artery disease

artículo científico publicado en 2006

Effect of tilarginine acetate in patients with acute myocardial infarction and cardiogenic shock: the TRIUMPH randomized controlled trial

artículo científico

Effects of Atrial Fibrillation on Treatment of Mitral Regurgitation in the EVEREST II (Endovascular Valve Edge-to-Edge Repair Study) Randomized Trial

article

Effects of Linagliptin on Cardiovascular and Kidney Outcomes in People With Normal and Reduced Kidney Function: Secondary Analysis of the CARMELINA Randomized Trial

artículo científico publicado en 2020

Effects of apixaban compared with warfarin as gain in event-free time - a novel assessment of the results of the ARISTOTLE trial

scientific article published on 07 November 2019

Efficacy and Safety of Apixaban Compared With Warfarin in Patients With Atrial Fibrillation and Peripheral Artery Disease: Insights From the ARISTOTLE Trial

artículo científico

Efficacy and Safety of Apixaban Compared With Warfarin in Patients With Atrial Fibrillation in Relation to Renal Function Over Time: Insights From the ARISTOTLE Randomized Clinical Trial

artículo científico

Efficacy and Safety of Apixaban Versus Warfarin in Patients With Atrial Fibrillation and Extremes in Body Weight

artículo científico publicado en 2019

Efficacy and Safety of Apixaban Versus Warfarin in Patients with Atrial Fibrillation and a History of Cancer: Insights from the ARISTOTLE Trial.

artículo científico publicado en 2017

Efficacy and Safety of Apixaban in Patients After Cardioversion for Atrial Fibrillation

article

Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fibrillation: a secondary analysis of a randomised controlled trial.

artículo científico publicado en 2012

Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for stroke prevention in atrial fibrillation.

artículo científico publicado en 2013

Efficacy and safety of apixaban compared with warfarin for stroke prevention in patients with atrial fibrillation from East Asia: a subanalysis of the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE

scientific article published on 06 June 2014

Efficacy and safety of apixaban vs warfarin in patients with atrial fibrillation and prior bioprosthetic valve replacement or valve repair: Insights from the ARISTOTLE trial

scientific article published on 09 April 2019

Efficacy and safety of edifoligide, an E2F transcription factor decoy, for prevention of vein graft failure following coronary artery bypass graft surgery: PREVENT IV: a randomized controlled trial

artículo científico publicado en 2005

Efficacy and safety of pyridoxal 5'-phosphate (MC-1) in high-risk patients undergoing coronary artery bypass graft surgery: the MEND-CABG II randomized clinical trial

artículo científico

Efficacy and safety of two unfractionated heparin dosing strategies with tenecteplase in acute myocardial infarction (results from Assessment of the Safety and Efficacy of a New Thrombolytic Regimens 2 and 3)

Efficacy of apixaban when compared with warfarin in relation to renal function in patients with atrial fibrillation: insights from the ARISTOTLE trial

artículo científico publicado en 2012

Efficacy of tenecteplase in combination with enoxaparin, abciximab, or unfractionated heparin: one-year follow-up results of the Assessment of the Safety of a New Thrombolytic-3 (ASSENT-3) randomized trial in acute myocardial infarction

artículo científico publicado en 2004

Elevated creatine kinase-MB with normal creatine kinase predicts worse outcomes in patients with acute coronary syndromes: results from 4 large clinical trials

artículo científico publicado en 2006

Endoscopic harvesting device type and outcomes in patients undergoing coronary artery bypass surgery

artículo científico publicado en 2014

Endoscopic versus open vein-graft harvesting in coronary-artery bypass surgery

artículo científico publicado en 2009

Enhancing Insights into Pulmonary Vascular Disease through a Precision Medicine Approach. A Joint NHLBI-Cardiovascular Medical Research and Education Fund Workshop Report.

artículo científico publicado en 2017

Evaluation of a new heparin agent in percutaneous coronary intervention: results of the phase 2 evaluation of M118 IN pErcutaNeous Coronary intErvention (EMINENCE) Trial

artículo científico publicado en 2010

Evaluation of potential antiplatelet effects of CSL112 (Apolipoprotein A-I [Human]) in patients with atherosclerosis: results from a phase 2a study.

artículo científico publicado en 2018

Evaluation of the Age, Biomarkers, and Clinical History-Bleeding Risk Score in Patients With Atrial Fibrillation With Combined Aspirin and Anticoagulation Therapy Enrolled in the ARISTOTLE and RE-LY Trials

scientific article published on 01 September 2020

Feasibility of point-of-care echocardiography by internal medicine house staff

artículo científico publicado en 2004

First clinical application of an actively reversible direct factor IXa inhibitor as an anticoagulation strategy in patients undergoing percutaneous coronary intervention

artículo científico publicado en 2010

First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology: a phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity

artículo científico publicado en 2006

Frequency and Predictors of Internal Mammary Artery Graft Failure and Subsequent Clinical Outcomes: Insights From the Project of Ex-vivo Vein Graft Engineering via Transfection (PREVENT) IV Trial

artículo científico publicado en 2015

Frequency, Regional Variation, and Predictors of Undetermined Cause of Death in Cardiometabolic Clinical Trials: A Pooled Analysis of 9259 Deaths in 9 Trials

scientific article published on 01 February 2019

Gastrointestinal bleeding in patients with atrial fibrillation treated with Apixaban or warfarin: Insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial

artículo científico publicado en 2019

Genome-wide association study of perioperative myocardial infarction after coronary artery bypass surgery

artículo científico publicado en 2015

Growth differentiation factor 15, a marker of oxidative stress and inflammation, for risk assessment in patients with atrial fibrillation: insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARI

artículo científico

Hand-held echocardiographic examination of patients with symptoms of acute coronary syndromes in the emergency department: the 30-day outcome associated with normal left ventricular wall motion

artículo científico publicado en 2004

Heterogeneity of diabetes as a risk factor for major adverse cardiovascular events in anticoagulated patients with atrial fibrillation: an analysis of the ARISTOTLE trial

artículo científico publicado en 2020

High-sensitivity troponin I for risk assessment in patients with atrial fibrillation: insights from the Apixaban for Reduction in Stroke and other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial

artículo científico publicado en 2013

High-sensitivity troponin T and risk stratification in patients with atrial fibrillation during treatment with apixaban or warfarin

artículo científico publicado en 2013

Highlights from the II International Symposium of Thrombosis and Anticoagulation (ISTA), October 22-23, 2009, São Paulo, Brazil.

artículo científico publicado en 2010

Highlights from the III International Symposium of Thrombosis and Anticoagulation (ISTA), October 14-16, 2010, São Paulo, Brazil

artículo científico publicado en 2011

History of bleeding and outcomes with apixaban versus warfarin in patients with atrial fibrillation in the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation trial.

artículo científico publicado en 2016

Hospitalization Among Patients With Atrial Fibrillation and a Recent Acute Coronary Syndrome or Percutaneous Coronary Intervention Treated With Apixaban or Aspirin: Insights From the AUGUSTUS Trial

artículo científico publicado en 2019

Impact of Left Ventricular to Mitral Valve Ring Mismatch on Recurrent Ischemic Mitral Regurgitation After Ring Annuloplasty

artículo científico publicado en 2016

Impact of extracardiac vascular disease on vein graft failure and outcomes after coronary artery bypass surgery

artículo científico publicado en 2013

Impact of perioperative myocardial infarction on angiographic and clinical outcomes following coronary artery bypass grafting (from PRoject of Ex-vivo Vein graft ENgineering via Transfection [PREVENT] IV).

artículo científico publicado en 2008

Impact of saphenous vein graft radiographic markers on clinical events and angiographic parameters

artículo científico publicado en 2008

Incidence and Outcomes Associated With Early Heart Failure Pharmacotherapy in Patients With Ongoing Cardiogenic Shock

scientific article published on 01 February 2014

Incidence, predictors, and outcomes of high-degree atrioventricular block complicating acute myocardial infarction treated with thrombolytic therapy

artículo científico publicado en 2005

Incidence, timing, and type of first and recurrent ischemic events in patients with and without peripheral artery disease after an acute coronary syndrome

artículo científico publicado en 2018

Incorporation of bleeding as an element of the composite end point in clinical trials of antithrombotic therapies in patients with non-ST-segment elevation acute coronary syndrome: validity, pitfalls, and future approaches

artículo científico

Incremental prognostic power of single-photon emission computed tomographic myocardial perfusion imaging in patients with known or suspected coronary artery disease.

artículo científico publicado en 2005

Independent data monitoring committees: preparing a path for the future

artículo científico publicado en 2014

Individual Patient Data from the Pivotal Randomized Controlled Trials of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation (COMBINE AF): Design and Rationale: From the COMBINE AF (A COllaboration between Multiple inst

scientific article published on 06 December 2020

Influence of body mass index on the efficacy of revascularization in patients with coronary artery disease

scientific article published on 04 March 2009

Influence of preoperative renal dysfunction on one-year bypass graft patency and two-year outcomes in patients undergoing coronary artery bypass surgery

artículo científico publicado en 2008

Infusion of Reconstituted High-Density Lipoprotein, CSL112, in Patients With Atherosclerosis: Safety and Pharmacokinetic Results From a Phase 2a Randomized Clinical Trial

artículo científico publicado en 2015

Inhibition of Factor Xa : a potential target for the development of new anticoagulants

artículo científico publicado en 2005

Inhibition of factor IXa by the pegnivacogin system during cardiopulmonary bypass: a potential substitute for heparin. A study in baboons

artículo científico publicado en 2015

Integrating antithrombin and antiplatelet therapies with early invasive management for non-ST-segment elevation acute coronary syndromes

artículo científico publicado en 2004

Interacting medication use and the treatment effects of apixaban versus warfarin: results from the ARISTOTLE Trial

scientific article published on 01 April 2019

International normalized ratio control and subsequent clinical outcomes in patients with atrial fibrillation using warfarin

scientific article published on 01 July 2019

Interplay between PCI access site, anticoagulant agent, and bleeding: Insights from the REGULATE-PCI randomized trial

artículo científico publicado en 2020

Intracranial hemorrhage in patients with atrial fibrillation receiving anticoagulation therapy

artículo científico publicado en 2017

Left ventricular systolic dysfunction, heart failure, and the risk of stroke and systemic embolism in patients with atrial fibrillation: insights from the ARISTOTLE trial

artículo científico

Levosimendan in Patients with Left Ventricular Dysfunction Undergoing Cardiac Surgery

artículo científico publicado en 2017

Levosimendan in patients with left ventricular systolic dysfunction undergoing cardiac surgery on cardiopulmonary bypass: Rationale and study design of the Levosimendan in Patients with Left Ventricular Systolic Dysfunction Undergoing Cardiac Surger

artículo científico publicado en 2016

Levosimendan in patients with reduced left ventricular function undergoing isolated coronary or valve surgery

scientific article published on 21 June 2019

Linagliptin Effects on Heart Failure and Related Outcomes in Individuals With Type 2 Diabetes Mellitus at High Cardiovascular and Renal Risk in CARMELINA

artículo científico publicado en 2019

Linagliptin and cardiorenal outcomes in Asians with type 2 diabetes mellitus and established cardiovascular and/or kidney disease: subgroup analysis of the randomized CARMELINA® trial

scientific article published on 22 October 2019

Long-term clinical and angiographic outcomes in patients with diabetes undergoing coronary artery bypass graft surgery: results from the Project of Ex-vivo Vein Graft Engineering via Transfection IV trial

artículo científico publicado en 2014

Long-term outcomes of mitral regurgitation by type and severity

scientific article published on 18 May 2018

Major Adverse Cardiovascular Events After 12 Months Among Patients With Acute Coronary Syndrome Receiving Loading Doses of Atorvastatin Prior to Planned PCI

artículo científico publicado en 2020

Major Bleeding in Patients With Atrial Fibrillation Receiving Apixaban or Warfarin

article

Management and clinical outcomes in patients treated with apixaban vs warfarin undergoing procedures

artículo científico publicado en 2014

Management and outcomes in patients with moderate or severe functional mitral regurgitation and severe left ventricular dysfunction

artículo científico publicado en 2015

Management of Atrial Fibrillation in Older Patients by Morbidity Burden: Insights From Get With The Guidelines-Atrial Fibrillation

scientific article published on 26 November 2020

Meta-analysis of intracranial hemorrhage in acute coronary syndromes: incidence, predictors, and clinical outcomes

artículo científico publicado en 2015

Minor myocardial damage and prognosis: are spontaneous and percutaneous coronary intervention-related events different?

artículo científico publicado en 2002

Navigating the treacherous waters of antithrombotic therapies in patients with atrial fibrillation and coronary artery disease: Lessons from AUGUSTUS

artículo científico publicado en 2019

New oral anticoagulants in addition to single or dual antiplatelet therapy after an acute coronary syndrome: a systematic review and meta-analysis

artículo científico publicado en 2013

Non-major bleeding with apixaban versus warfarin in patients with atrial fibrillation

artículo científico publicado en 2016

Nonsteroidal Anti-Inflammatory Drugs and Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Surgery

artículo científico publicado en 2016

Novel oral anticoagulants after acute coronary syndromes

artículo científico

Obesity paradox on outcome in atrial fibrillation maintained even considering the prognostic influence of biomarkers: insights from the ARISTOTLE trial

article published in 2018

Obesity, Diabetes, and Acute Coronary Syndrome: Differences Between Asians and Whites

artículo científico publicado en 2017

One-year follow-up of the ASSENT-2 trial: A double-blind, randomized comparison of single-bolus tenecteplase and front-loaded alteplase in 16,949 patients with ST-elevation acute myocardial infarction

artículo científico publicado en 2003

Optimal Antithrombotic Regimens for Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention: An Updated Network Meta-analysis

artículo científico publicado en 2020

Outcomes associated with the use of secondary prevention medications after coronary artery bypass graft surgery

scientific article published on 01 March 2007

Outcomes following revascularization with radial artery bypass grafts: Insights from the PREVENT-IV trial

artículo científico publicado en 2020

Outcomes in anticoagulated patients with atrial fibrillation and with mitral or aortic valve disease

artículo científico publicado en 2018

Outcomes of apixaban versus warfarin in patients with atrial fibrillation and multi-morbidity: Insights from the ARISTOTLE trial

scientific article published on 22 November 2018

Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial

artículo científico publicado en 2013

Patients With Atrial Fibrillation Taking Nonsteroidal Anti-Inflammatory Drugs and Oral Anticoagulants in the ARISTOTLE Trial

scientific article published on 21 November 2019

Patterns of management of atrial fibrillation complicating coronary artery bypass grafting: Results from the PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT-IV) Trial

artículo científico publicado en 2009

Pegnivacogin results in near complete FIX inhibition in acute coronary syndrome patients: RADAR pharmacokinetic and pharmacodynamic substudy

artículo científico publicado en 2011

Percutaneous coronary intervention and antiplatelet therapy in patients with atrial fibrillation receiving apixaban or warfarin: Insights from the ARISTOTLE trial

artículo científico publicado en 2017

Performance and Validation of a Novel Biomarker-Based Stroke Risk Score for Atrial Fibrillation

artículo científico

Perioperative management of anticoagulation: guidelines translated for the clinician

scientific article published on 26 February 2009

Phase 1b randomized study of antidote-controlled modulation of factor IXa activity in patients with stable coronary artery disease

artículo científico publicado en 2008

Pneumonia after cardiac surgery: Experience of the National Institutes of Health/Canadian Institutes of Health Research Cardiothoracic Surgical Trials Network

artículo científico publicado en 2017

Polypharmacy and effects of apixaban versus warfarin in patients with atrial fibrillation: post hoc analysis of the ARISTOTLE trial

artículo científico publicado en 2016

Pooled analysis of adverse event collection from 4 acute coronary syndrome trials

artículo científico publicado en 2016

Post-Discharge Bleeding and Mortality Following Acute Coronary Syndromes With or Without PCI

scientific article published on 01 July 2020

Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer

artículo científico publicado en 2016

Pre-existing anti-polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer

artículo científico publicado en 2015

Predictors of 30-day mortality in patients with refractory cardiogenic shock following acute myocardial infarction despite a patent infarct artery

artículo científico publicado en 2009

Predictors of long-term clinical endpoints in patients with refractory angina

artículo científico publicado en 2015

Premature permanent discontinuation of apixaban or warfarin in patients with atrial fibrillation

artículo científico publicado en 2020

Prior aspirin use predicts worse outcomes in patients with non–ST-elevation acute coronary syndromes11This study was sponsored by COR Therapeutics Inc., South San Francisco, California; and Schering-Plough Research Institute, Kenilworth, New Jersey

article

Prognostic importance of new small Q waves following non-ST-elevation acute coronary syndromes

artículo científico publicado en 2003

Promise of factor Xa inhibition in atrial fibrillation

artículo científico

Prophylaxis for venous thromboembolism: guidelines translated for the clinician ⬇️

artículo científico publicado el 1 de enero de 2011

REGULATE-PCI trial--Author's reply

artículo científico publicado en 2016

Race, Bleeding, and Outcomes in STEMI Patients Treated with Fibrinolytic Therapy

artículo científico publicado en 2011

Randomized Trials Versus Common Sense and Clinical Observation: JACC Review Topic of the Week

artículo científico publicado en 2020

Randomized, double-blind, dose-ranging study of otamixaban, a novel, parenteral, short-acting direct factor Xa inhibitor, in percutaneous coronary intervention: the SEPIA-PCI trial

scientific article published on 14 May 2007

Rate versus rhythm control and outcomes in patients with atrial fibrillation and chronic kidney disease: data from the GUSTO-III Trial

artículo científico publicado en 2013

Rationale and design of Apo-I Event Reduction in Ischemic Syndromes I (AEGIS-I): A phase 2b, randomized, placebo-controlled, dose-ranging trial to investigate the safety and tolerability of CSL112, a reconstituted, infusible, human apoA-I, after acu

artículo científico publicado en 2016

Rationale and design of ApoA-I event reducing in ischemic syndromes II (AEGIS-II): A phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to investigate the efficacy and safety of CSL112 in subjects after acute my

artículo científico publicado en 2020

Rationale and design of PROACT Xa: A randomized, multicenter, open-label, clinical trial to evaluate the efficacy and safety of apixaban versus warfarin in patients with a mechanical On-X Aortic Heart Valve

artículo científico publicado en 2020

Rationale and design of the Statins Evaluation in Coronary procedUres and REvascularization: The SECURE-PCI Trial

artículo científico publicado en 2018

Rationale and strategies for implementing community-based transfer protocols for primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction

artículo científico publicado en 2004

Rationale, design, and baseline characteristics of the CArdiovascular safety and Renal Microvascular outcomE study with LINAgliptin (CARMELINA®): a randomized, double-blind, placebo-controlled clinical trial in patients with type 2 diabetes and high

artículo científico publicado en 2018

Readmissions after cardiac surgery: experience of the National Institutes of Health/Canadian Institutes of Health research cardiothoracic surgical trials network.

artículo científico publicado en 2014

Regional variation in clinical characteristics and outcomes in patients with atrial fibrillation: Findings from the ARISTOTLE trial

scientific article published on 30 December 2019

Relation of Post-Coronary Artery Bypass Graft Creatine Kinase-MB Elevations and New Q Waves With Long-Term Cardiovascular Death in Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease

artículo científico publicado en 2016

Relation of early saphenous vein graft failure to outcomes following coronary artery bypass surgery

scientific article published on 06 September 2005

Relationship between postoperative clopidogrel use and subsequent angiographic and clinical outcomes following coronary artery bypass grafting

artículo científico publicado en 2013

Relationship between vein graft failure and subsequent clinical outcomes after coronary artery bypass surgery

artículo científico publicado en 2012

Relationship of Incorrect Dosing of Fibrinolytic Therapy and Clinical Outcomes

artículo científico publicado en 2005

Repeated Measurements of Cardiac Biomarkers in Atrial Fibrillation and Validation of the ABC Stroke Score Over Time

artículo científico publicado en 2017

Reply: Specifics of Dose Modification in ARISTOTLE

artículo científico publicado en 2020

Reply: To PMID 24360877

artículo científico publicado en 2014

Reporting Clinical End Points and Safety Events in an Acute Coronary Syndrome Trial: Results With Integrated Collection.

artículo científico

Response to Letters Regarding Article, "Frequency and Predictors of Internal Mammary Artery Graft Failure and Subsequent Clinical Outcomes: Insights From the Project of Ex-Vivo Vein Graft Engineering via Transfection (PREVENT) IV Trial".

artículo científico publicado en 2016

Response to Letters Regarding Article, "Saphenous Vein Graft Failure After Coronary Artery Bypass Surgery: Insights From PREVENT IV".

artículo científico publicado en 2015

Response to letter regarding article, "Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for stroke prevention in atrial fibrillation".

artículo científico publicado en 2014

Response to letter regarding article, "surgical revascularization is associated with maximal survival in patients with ischemic mitral regurgitation: a 20-year experience".

artículo científico publicado en 2015

Rivaroxaban in Patients with Atrial Fibrillation and a Bioprosthetic Mitral Valve

artículo científico publicado en 2020

SUN-LB015 Baseline Characteristics and Effects on CV and Kidney Outcomes with Linagliptin Versus Placebo, Across GFR Categories in CARMELINA.

artículo científico publicado en 2019

Safe and Effective Anticoagulation: What Does Drug Concentration Add?

artículo científico publicado en 2019

Safety and Efficacy of Antithrombotic Strategies in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention: A Network Meta-analysis of Randomized Controlled Trials

scientific article published on 19 June 2019

Safety and Tolerability of CSL112, a Reconstituted, Infusible, Plasma-Derived Apolipoprotein A-I, After Acute Myocardial Infarction: The AEGIS-I Trial (ApoA-I Event Reducing in Ischemic Syndromes I).

artículo científico publicado en 2016

Safety of very early sheath removal in patients treated with REG1 for acute coronary syndromes: insights from the RADAR trial.

artículo científico publicado en 2013

Saphenous vein graft failure after coronary artery bypass surgery: insights from PREVENT IV.

artículo científico publicado en 2014

Saphenous vein graft failure after coronary artery bypass surgery: pathophysiology, management, and future directions

artículo científico

Saphenous vein graft failure and clinical outcomes: toward a surrogate end point in patients following coronary artery bypass surgery?

artículo científico publicado en 2013

Saphenous vein grafts with multiple versus single distal targets in patients undergoing coronary artery bypass surgery: one-year graft failure and five-year outcomes from the Project of Ex-Vivo Vein Graft Engineering via Transfection (PREVENT) IV tr

scientific article published on 27 June 2011

Screening for structural heart disease: time to stop listening and start looking ⬇️

artículo científico publicado el 1 de octubre de 2003

Screening of Multiple Biomarkers Associated With Ischemic Stroke in Atrial Fibrillation

scientific article published on 09 December 2020

Secondary surgical-site infection after coronary artery bypass grafting: A multi-institutional prospective cohort study

artículo científico publicado en 2017

Serial measurement of interleukin-6 and risk of mortality in anticoagulated patients with atrial fibrillation: Insights from ARISTOTLE and RE-LY trials

artículo científico publicado en 2020

Sex-Stratified Trends in Enrollment, Patient Characteristics, Treatment, and Outcomes Among Non-ST-Segment Elevation Acute Coronary Syndrome Patients: Insights From Clinical Trials Over 17 Years

artículo científico publicado en 2015

Standardizing definitions for hybrid coronary revascularization

artículo científico publicado en 2013

Status quo of hybrid coronary revascularization for multi-vessel coronary artery disease

artículo científico publicado en 2013

Stent Thrombosis in Patients With Atrial Fibrillation Undergoing Coronary Stenting in the AUGUSTUS Trial

scientific article published on 11 November 2019

Stroke prevention in atrial fibrillation: re-defining 'real-world data' within the broader data universe

artículo científico publicado en 2018

Sudden Cardiac Death After Non-ST-Segment Elevation Acute Coronary Syndrome

artículo científico publicado en 2016

Surgical revascularization is associated with maximal survival in patients with ischemic mitral regurgitation: a 20-year experience

artículo científico publicado en 2014

Surgical revision after percutaneous mitral repair with the MitraClip device.

artículo científico publicado en 2010

Surgical treatment of moderate ischemic mitral regurgitation

artículo científico publicado en 2014

The 'obesity paradox' in atrial fibrillation: observations from the ARISTOTLE (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation) trial.

artículo científico publicado en 2016

The ABC (age, biomarkers, clinical history) stroke risk score: a biomarker-based risk score for predicting stroke in atrial fibrillation

artículo científico publicado en 2016

The CSL112-2001 trial: Safety and tolerability of multiple doses of CSL112 (apolipoprotein A-I [human]), an intravenous formulation of plasma-derived apolipoprotein A-I, among subjects with moderate renal impairment after acute myocardial infarction

artículo científico publicado en 2018

The PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT IV) trial: study rationale, design, and baseline patient characteristics

artículo científico publicado en 2005

The Preservation and Handling of Vein Grafts in Current Surgical Practice: Findings of a Survey Among Cardiovascular Surgeons of Top-Ranked US Hospitals

artículo científico publicado en 2015

The Risk / Benefit Tradeoff of Antithrombotic Therapy in Patients with Atrial Fibrillation Early and Late After an Acute Coronary Syndrome or Percutaneous Coronary Intervention: Insights from AUGUSTUS

artículo científico publicado en 2020

The Role of Cardiovascular Implantable Electronic Devices in the Detection and Treatment of Subclinical Atrial Fibrillation: A Review

artículo científico publicado en 2017

The clinical evaluation of the Endeavor zotarolimus-eluting coronary stent in Japanese patients with de novo native coronary artery lesions: primary results and 3-year follow-up of the Endeavor Japan study ⬇️

artículo científico publicado el 1 de septiembre de 2011

The future of cardiovascular clinical research in North America and beyond-addressing challenges and leveraging opportunities through unique academic and grassroots collaborations

artículo científico

The kinetics of integrilin limited by obesity: a multicenter randomized pharmacokinetic and pharmacodynamic clinical trial

artículo científico publicado en 2011

The novel biomarker-based ABC (age, biomarkers, clinical history)-bleeding risk score for patients with atrial fibrillation: a derivation and validation study.

artículo científico publicado en 2016

The safety and efficacy of apixaban : where do we stand in 2013?

artículo científico

Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial

scholarly article by Renato D Lopes published in 2021

Thrombomodulin gene variants are associated with increased mortality after coronary artery bypass surgery in replicated analyses

artículo científico publicado en 2011

Time course of degradation of cardiac troponin I in patients with acute ST-elevation myocardial infarction: the ASSENT-2 troponin substudy

artículo científico publicado en 2006

Timing of Loading Dose of Atorvastatin in Patients Undergoing Percutaneous Coronary Intervention for Acute Coronary Syndromes: Insights From the SECURE-PCI Randomized Clinical Trial

artículo científico publicado en 2018

Transcatheter mitral valve repair for functional mitral regurgitation: Evaluating the evidence

artículo científico publicado en 2020

Treatment of venous thromboembolism: guidelines translated for the clinician

scientific article published on October 2009

Trends in Enrollment, Clinical Characteristics, Treatment, and Outcomes According to Age in Non-ST-Segment-Elevation Acute Coronary Syndromes Clinical Trials

artículo científico publicado en 2016

Use of Biomarkers to Predict Specific Causes of Death in Patients With Atrial Fibrillation

artículo científico publicado en 2018

Use of the REG1 anticoagulation system in patients with acute coronary syndromes undergoing percutaneous coronary intervention: results from the phase II RADAR-PCI study

scientific article published on 01 August 2014

Vascular endothelial tissue factor pathway inhibitor kinetics in culture following exposure to DX-9065a--a selective and direct factor Xa inhibitor

artículo científico publicado en 2004

Vein graft preservation solutions, patency, and outcomes after coronary artery bypass graft surgery: follow-up from the PREVENT IV randomized clinical trial

artículo científico publicado en 2014

Warfarin use and long-term outcomes in patients with acute myocardial infarction and atrial fibrillation

artículo científico publicado en 2014

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