Lista de obras -

A cytotoxic factor for glial cells: a new avenue of research for multiple sclerosis?

artículo científico publicado en 1997

A gliotoxic factor and multiple sclerosis

artículo científico publicado en 1998

A new therapeutic approach for type 1 diabetes: rationale for GNbAC1 an anti-HERV-W-Env monoclonal antibody.

artículo científico publicado en 2018

A phase IIa randomised clinical study of GNbAC1, a humanised monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus in multiple sclerosis patients

artículo científico publicado en 2014

A phase IIa randomized clinical study testing GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis associated endogenous retrovirus in multiple sclerosis patients - a twelve month follow-up

artículo científico publicado en 2015

A urinary marker for multiple sclerosis

artículo científico publicado en 1998

An ancestral retroviral protein identified as a therapeutic target in type-1 diabetes

artículo científico publicado en 2017

Antibody to reverse transcriptase of human retroviruses in multiple sclerosis

artículo científico publicado en 1991

Case report: DNA fragmentation in glial cells in a cerebral biopsy from a multiple sclerosis patient

artículo científico publicado en 1998

Cell cultures and associated retroviruses in multiple sclerosis. Collaborative Research Group on MS.

artículo científico publicado en 1997

Correlation between disease severity and in vitro cytokine production mediated by MSRV (Multiple Sclerosis associated RetroViral element) envelope protein in patients with multiple sclerosis

scientific article published on 08 December 2004

Correlation between milk and dairy product consumption and multiple sclerosis prevalence: a worldwide study

artículo científico publicado en 1992

Coxsackievirus-B4 Infection Can Induce the Expression of Human Endogenous Retrovirus W in Primary Cells

artículo científico publicado en 2020

Detection of a gliotoxic activity in the cerebrospinal fluid from multiple sclerosis patients

scientific article published on 01 March 1998

Detection of virion-associated MSRV-RNA in serum of patients with multiple sclerosis

artículo científico publicado en 1998

Development of a pan-retrovirus detection system for multiple sclerosis studies.

artículo científico publicado en 1997

Endogenous retroviral genes, Herpesviruses and gender in Multiple Sclerosis

artículo científico publicado en 2009

Endogenous retroviral sequences in the human genome can play a physiological or pathological role

artículo científico publicado en 2017

Endogenous retrovirus type W GAG and ENV antigenaemia in serum of schizophrenic patients

artículo científico publicado en 2009

Endogenous retrovirus type W GAG and envelope protein antigenemia in serum of schizophrenic patients

artículo científico publicado en 2008

Erratum: Molecular characteristics of Human Endogenous Retrovirus type-W in schizophrenia and bipolar disorder

scholarly article published in Translational Psychiatry

Exposure to infant siblings during early life and risk of multiple sclerosis

scientific article published on 01 May 2005

Expression of endogenous retroviruses in blood mononuclear cells and brain tissue from multiple sclerosis patients

artículo científico publicado en 1995

Expression of endogenous retroviruses in blood mononuclear cells and brain tissue from multiple sclerosis patients

scientific article published on 01 January 1997

First international workshop on human endogenous retroviruses and diseases, HERVs & disease 2015

artículo científico publicado en 2015

GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus: a first-in-humans randomized clinical study

artículo científico publicado en 2012

Glial toxicity in urine and multiple sclerosis

artículo científico publicado en 2001

Gliotoxic factor and multiple sclerosis

artículo científico publicado en 1996

Gliotoxicity, reverse transcriptase activity and retroviral RNA in monocyte/macrophage culture supernatants from patients with multiple sclerosis

artículo científico publicado en 1997

HERV-W envelope is significantly expressed in Multiple Sclerosis and causes neuroinflammation in animal models with specific antibody inhibition

Herpes simplex virus ICP0 and ICP4 immediate early proteins strongly enhance expression of a retrovirus harboured by a leptomeningeal cell line from a patient with multiple sclerosis

artículo científico publicado en 1993

Human Endogenous Retrovirus and Neuroinflammation in Chronic Inflammatory Demyelinating Polyradiculoneuropathy.

artículo científico publicado en 2016

Human Endogenous Retroviruses and Type 1 Diabetes

scientific article published on 21 November 2019

Human Endogenous Retroviruses in Neurological Diseases.

artículo científico publicado en 2018

Human endogenous retroviral protein triggers deficit in glutamate synapse maturation and behaviors associated with psychosis

scientific article published on 17 July 2020

Human endogenous retrovirus (HERV)-W ENV and GAG proteins: physiological expression in human brain and pathophysiological modulation in multiple sclerosis lesions

artículo científico publicado en 2005

Human endogenous retrovirus W in brain lesions: Rationale for targeted therapy in multiple sclerosis

artículo científico publicado en 2016

Human endogenous retrovirus protein activates innate immunity and promotes experimental allergic encephalomyelitis in mice

artículo científico publicado en 2013

Human endogenous retrovirus type W (HERV-W) in schizophrenia: a new avenue of research at the gene-environment interface

artículo científico publicado en 2011

Human endogenous retrovirus type W envelope expression in blood and brain cells provides new insights into multiple sclerosis disease.

artículo científico publicado en 2012

Human endogenous retrovirus type W envelope protein inhibits oligodendroglial precursor cell differentiation

artículo científico publicado en 2013

Human viral superantigens: to be or not to be transactivated?

artículo científico publicado en 2002

In vitro transmission and antigenicity of a retrovirus isolated from a multiple sclerosis patient

artículo científico publicado en 1992

Induction of Proinflammatory Multiple Sclerosis-Associated Retrovirus Envelope Protein by Human Herpesvirus-6A and CD46 Receptor Engagement

artículo científico publicado en 2018

Inflammatory response of endothelial cells to a human endogenous retrovirus associated with multiple sclerosis is mediated by TLR4.

artículo científico publicado en 2015

Infrequency of detection of particle-associated MSRV/HERV-W RNA in the synovial fluid of patients with rheumatoid arthritis

scientific article published on 01 September 2000

Isolation of retrovirus from patients with multiple sclerosis

artículo científico publicado en 1991

Leptomeningeal cell line from multiple sclerosis with reverse transcriptase activity and viral particles

artículo científico publicado en 1989

MSRV envelope protein is a potent, endogenous and pathogenic agonist of human toll-like receptor 4: Relevance of GNbAC1 in multiple sclerosis treatment

artículo científico publicado en 2015

MSRV, Syncytin and the role of endogenous retroviral proteins in demyelination

scientific article published on 01 April 2005

Meeting report: "Human endogenous retroviruses: HERVs or transposable elements in autoimmune, chronic inflammatory and degenerative diseases or cancer", Lyon, France, november 5th and 6th 2019 - an MS scientist's digest

scientific article published on 08 April 2020

Molecular characteristics of Human Endogenous Retrovirus type-W in schizophrenia and bipolar disorder.

artículo científico publicado en 2012

Molecular characteristics of Human Endogenous Retrovirus type-W in schizophrenia and bipolar disorder.

artículo científico publicado en 2013

Molecular characterization and placental expression of HERV-W, a new human endogenous retrovirus family.

artículo científico publicado en 1999

Molecular cloning and characterization of MSRV-related sequences associated with retrovirus-like particles

artículo científico publicado en 1999

Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis. The Collaborative Research Group on Multiple Sclerosis

artículo científico publicado en 1997

Multiple sclerosis retrovirus particles and recombinant envelope trigger an abnormal immune response in vitro, by inducing polyclonal Vbeta16 T-lymphocyte activation

artículo científico publicado en 2001

Multiple sclerosis-associated retroviral agent (MSRV)-stimulated cytokine production in patients with relapsing-remitting multiple sclerosis.

artículo científico publicado en 2009

Multiple sclerosis-associated retrovirus and related human endogenous retrovirus-W in patients with multiple sclerosis.

artículo científico publicado en 2013

Multiple sclerosis-associated retrovirus particles cause T lymphocyte-dependent death with brain hemorrhage in humanized SCID mice model

artículo científico publicado en 2003

Phylogeny of a novel family of human endogenous retrovirus sequences, HERV-W, in humans and other primates

artículo científico publicado en 1999

Preclinical and early clinical development of GNbAC1, a humanized IgG4 monoclonal antibody targeting endogenous retroviral MSRV-Env protein

artículo científico publicado en 2015

Prehistoric enemies within: The contribution of human endogenous retroviruses to neurological diseases. Meeting report: "Second International Workshop on Human Endogenous Retroviruses and Disease", Washington DC, March 13th and 14th 2017.

artículo científico publicado en 2017

Re: Errors in the editorial by Christensen and Giovannoni [HERVs: have we been here before? MSJ 18(12) 1670-1672].

artículo científico publicado en 2013

Reduced expression of human endogenous retrovirus (HERV)-W GAG protein in the cingulate gyrus and hippocampus in schizophrenia, bipolar disorder, and depression

artículo científico publicado en 2007

Regulation of human endogenous retrovirus W protein expression by herpes simplex virus type 1: implications for multiple sclerosis

artículo científico publicado en 2006

Reply to Ruprecht and Mayer: Unearthing genomic fossils in the pathogenesis of multiple sclerosis

scientific article published on 27 August 2019

Rescuing the negative impact of human endogenous retrovirus envelope protein on oligodendroglial differentiation and myelination

scientific article published on 14 November 2018

Specificities of multiple sclerosis cerebrospinal fluid and serum antibodies against mimotopes

artículo científico publicado en 1999

Sporadic ALS/MND: a global neurodegeneration with retroviral involvement?

artículo científico publicado en 1995

The DNA copy number of human endogenous retrovirus-W (MSRV-type) is increased in multiple sclerosis patients and is influenced by gender and disease severity

artículo científico publicado en 2013

The envelope of human endogenous retrovirus in neuro-inflammation

The envelope protein of a human endogenous retrovirus-W family activates innate immunity through CD14/TLR4 and promotes Th1-like responses

artículo científico publicado en 2006

The human endogenous retrovirus link between genes and environment in multiple sclerosis and in multifactorial diseases associating neuroinflammation

artículo científico publicado en 2010

The multiple sclerosis-associated retrovirus and its HERV-W endogenous family: a biological interface between virology, genetics, and immunology in human physiology and disease

artículo científico publicado en 2008

The neutralizing antibody GNbAC1 abrogates HERV-W envelope protein-mediated oligodendroglial maturation blockade

artículo científico publicado en 2014

Treatment against human endogenous retrovirus: a possible personalized medicine approach for multiple sclerosis

artículo científico publicado en 2015

Variation in proviral content among human genomes mediated by LTR recombination

scholarly article by Jainy Thomas published in January 2018

[DNA sequences from mobile genetic elements, a hidden half of the human genome].

artículo científico publicado en 2017

pHERV-W envelope protein fuels microglial cell-dependent damage of myelinated axons in multiple sclerosis

scientific article published on 18 June 2019

Lista de obras de

A cytotoxic factor for glial cells: a new avenue of research for multiple sclerosis?

A gliotoxic factor and multiple sclerosis

A new therapeutic approach for type 1 diabetes: rationale for GNbAC1 an anti-HERV-W-Env monoclonal antibody.

A phase IIa randomised clinical study of GNbAC1, a humanised monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus in multiple sclerosis patients

A phase IIa randomized clinical study testing GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis associated endogenous retrovirus in multiple sclerosis patients - a twelve month follow-up

A urinary marker for multiple sclerosis

An ancestral retroviral protein identified as a therapeutic target in type-1 diabetes

Antibody to reverse transcriptase of human retroviruses in multiple sclerosis

Case report: DNA fragmentation in glial cells in a cerebral biopsy from a multiple sclerosis patient

Cell cultures and associated retroviruses in multiple sclerosis. Collaborative Research Group on MS.

Correlation between disease severity and in vitro cytokine production mediated by MSRV (Multiple Sclerosis associated RetroViral element) envelope protein in patients with multiple sclerosis

Correlation between milk and dairy product consumption and multiple sclerosis prevalence: a worldwide study

Coxsackievirus-B4 Infection Can Induce the Expression of Human Endogenous Retrovirus W in Primary Cells

Detection of a gliotoxic activity in the cerebrospinal fluid from multiple sclerosis patients

Detection of virion-associated MSRV-RNA in serum of patients with multiple sclerosis

Development of a pan-retrovirus detection system for multiple sclerosis studies.

Endogenous retroviral genes, Herpesviruses and gender in Multiple Sclerosis

Endogenous retroviral sequences in the human genome can play a physiological or pathological role

Endogenous retrovirus type W GAG and ENV antigenaemia in serum of schizophrenic patients

Endogenous retrovirus type W GAG and envelope protein antigenemia in serum of schizophrenic patients

Erratum: Molecular characteristics of Human Endogenous Retrovirus type-W in schizophrenia and bipolar disorder

Exposure to infant siblings during early life and risk of multiple sclerosis

Expression of endogenous retroviruses in blood mononuclear cells and brain tissue from multiple sclerosis patients

Expression of endogenous retroviruses in blood mononuclear cells and brain tissue from multiple sclerosis patients

First international workshop on human endogenous retroviruses and diseases, HERVs & disease 2015

GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus: a first-in-humans randomized clinical study

Glial toxicity in urine and multiple sclerosis

Gliotoxic factor and multiple sclerosis

Gliotoxicity, reverse transcriptase activity and retroviral RNA in monocyte/macrophage culture supernatants from patients with multiple sclerosis

HERV-W envelope is significantly expressed in Multiple Sclerosis and causes neuroinflammation in animal models with specific antibody inhibition

Herpes simplex virus ICP0 and ICP4 immediate early proteins strongly enhance expression of a retrovirus harboured by a leptomeningeal cell line from a patient with multiple sclerosis

Human Endogenous Retrovirus and Neuroinflammation in Chronic Inflammatory Demyelinating Polyradiculoneuropathy.

Human Endogenous Retroviruses and Type 1 Diabetes

Human Endogenous Retroviruses in Neurological Diseases.

Human endogenous retroviral protein triggers deficit in glutamate synapse maturation and behaviors associated with psychosis

Human endogenous retrovirus (HERV)-W ENV and GAG proteins: physiological expression in human brain and pathophysiological modulation in multiple sclerosis lesions

Human endogenous retrovirus W in brain lesions: Rationale for targeted therapy in multiple sclerosis

Human endogenous retrovirus protein activates innate immunity and promotes experimental allergic encephalomyelitis in mice

Human endogenous retrovirus type W (HERV-W) in schizophrenia: a new avenue of research at the gene-environment interface

Human endogenous retrovirus type W envelope expression in blood and brain cells provides new insights into multiple sclerosis disease.

Human endogenous retrovirus type W envelope protein inhibits oligodendroglial precursor cell differentiation

Human viral superantigens: to be or not to be transactivated?

In vitro transmission and antigenicity of a retrovirus isolated from a multiple sclerosis patient

Induction of Proinflammatory Multiple Sclerosis-Associated Retrovirus Envelope Protein by Human Herpesvirus-6A and CD46 Receptor Engagement

Inflammatory response of endothelial cells to a human endogenous retrovirus associated with multiple sclerosis is mediated by TLR4.

Infrequency of detection of particle-associated MSRV/HERV-W RNA in the synovial fluid of patients with rheumatoid arthritis

Isolation of retrovirus from patients with multiple sclerosis

Leptomeningeal cell line from multiple sclerosis with reverse transcriptase activity and viral particles

MSRV envelope protein is a potent, endogenous and pathogenic agonist of human toll-like receptor 4: Relevance of GNbAC1 in multiple sclerosis treatment

MSRV, Syncytin and the role of endogenous retroviral proteins in demyelination

Meeting report: "Human endogenous retroviruses: HERVs or transposable elements in autoimmune, chronic inflammatory and degenerative diseases or cancer", Lyon, France, november 5th and 6th 2019 - an MS scientist's digest

Molecular characteristics of Human Endogenous Retrovirus type-W in schizophrenia and bipolar disorder.

Molecular characteristics of Human Endogenous Retrovirus type-W in schizophrenia and bipolar disorder.

Molecular characterization and placental expression of HERV-W, a new human endogenous retrovirus family.

Molecular cloning and characterization of MSRV-related sequences associated with retrovirus-like particles

Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis. The Collaborative Research Group on Multiple Sclerosis

Multiple sclerosis retrovirus particles and recombinant envelope trigger an abnormal immune response in vitro, by inducing polyclonal Vbeta16 T-lymphocyte activation

Multiple sclerosis-associated retroviral agent (MSRV)-stimulated cytokine production in patients with relapsing-remitting multiple sclerosis.

Multiple sclerosis-associated retrovirus and related human endogenous retrovirus-W in patients with multiple sclerosis.

Multiple sclerosis-associated retrovirus particles cause T lymphocyte-dependent death with brain hemorrhage in humanized SCID mice model

Phylogeny of a novel family of human endogenous retrovirus sequences, HERV-W, in humans and other primates

Preclinical and early clinical development of GNbAC1, a humanized IgG4 monoclonal antibody targeting endogenous retroviral MSRV-Env protein

Prehistoric enemies within: The contribution of human endogenous retroviruses to neurological diseases. Meeting report: "Second International Workshop on Human Endogenous Retroviruses and Disease", Washington DC, March 13th and 14th 2017.

Re: Errors in the editorial by Christensen and Giovannoni [HERVs: have we been here before? MSJ 18(12) 1670-1672].

Reduced expression of human endogenous retrovirus (HERV)-W GAG protein in the cingulate gyrus and hippocampus in schizophrenia, bipolar disorder, and depression

Regulation of human endogenous retrovirus W protein expression by herpes simplex virus type 1: implications for multiple sclerosis

Reply to Ruprecht and Mayer: Unearthing genomic fossils in the pathogenesis of multiple sclerosis

Rescuing the negative impact of human endogenous retrovirus envelope protein on oligodendroglial differentiation and myelination

Specificities of multiple sclerosis cerebrospinal fluid and serum antibodies against mimotopes

Sporadic ALS/MND: a global neurodegeneration with retroviral involvement?

The DNA copy number of human endogenous retrovirus-W (MSRV-type) is increased in multiple sclerosis patients and is influenced by gender and disease severity

The envelope of human endogenous retrovirus in neuro-inflammation

The envelope protein of a human endogenous retrovirus-W family activates innate immunity through CD14/TLR4 and promotes Th1-like responses

The human endogenous retrovirus link between genes and environment in multiple sclerosis and in multifactorial diseases associating neuroinflammation

The multiple sclerosis-associated retrovirus and its HERV-W endogenous family: a biological interface between virology, genetics, and immunology in human physiology and disease

The neutralizing antibody GNbAC1 abrogates HERV-W envelope protein-mediated oligodendroglial maturation blockade

Treatment against human endogenous retrovirus: a possible personalized medicine approach for multiple sclerosis

Variation in proviral content among human genomes mediated by LTR recombination

[DNA sequences from mobile genetic elements, a hidden half of the human genome].