Lista de obras -

A 1,536-well [(35)S]GTPgammaS scintillation proximity binding assay for ultra-high-throughput screening of an orphan galphai-coupled GPCR.

artículo científico publicado en 2008

A 1,536-well ultra-high-throughput siRNA screen to identify regulators of the Wnt/beta-catenin pathway

artículo científico publicado en 2010

A 1536-well cAMP assay for Gs- and Gi-coupled receptors using enzyme fragmentation complementation.

artículo científico publicado en 2004

A beta-lactamase-dependent Gal4-estrogen receptor beta transactivation assay for the ultra-high throughput screening of estrogen receptor beta agonists in a 3456-well format

artículo científico publicado en 2003

A cell-based beta-lactamase reporter gene assay for the identification of inhibitors of hepatitis C virus replication

artículo científico publicado en 2004

A cell-based ultra-high-throughput screening assay for identifying inhibitors of D-amino acid oxidase

artículo científico publicado en 2006

A collaborative screening program for the discovery of inhibitors of HCV NS2/3 cis-cleaving protease activity

artículo científico publicado en 2002

A fluorescence-based thiol quantification assay for ultra-high-throughput screening for inhibitors of coenzyme A production

artículo científico publicado en 2008

A fully automated [35S]GTPgammaS scintillation proximity assay for the high-throughput screening of Gi-linked G protein-coupled receptors

artículo científico publicado en 2003

A high-precision fluorogenic cholesteryl ester transfer protein assay compatible with animal serum and 3456-well assay technology

artículo científico publicado en 2007

A miniaturized cell-based fluorescence resonance energy transfer assay for insulin-receptor activation

artículo científico publicado en 2006

A multiplexed siRNA screening strategy to identify genes in the PARP pathway.

artículo científico publicado en 2012

A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists

artículo científico publicado en 2004

A short-incubation reporter-gene assay for high-throughput screening of estrogen receptor-alpha antagonists

artículo científico publicado en 2005

An efficient and fully automated high-throughput transfection method for genome-scale siRNA screens

artículo científico publicado en 2008

Application of division arrest technology to cell-based HTS: comparison with frozen and fresh cells

artículo científico publicado en 2005

Application of real-time cell electronic sensing (RT-CES) technology to cell-based assays

artículo científico publicado en 2004

Compounds that bind APP and inhibit Abeta processing in vitro suggest a novel approach to Alzheimer disease therapeutics

artículo científico publicado en 2005

Current trends in high-throughput screening

artículo científico publicado en 2008

Development of an intact cell reporter gene beta-lactamase assay for G protein-coupled receptors for high-throughput screening

artículo científico publicado en 2003

Development of an oxazolopyridine series of dual thrombin/factor Xa inhibitors via structure-guided lead optimization

artículo científico publicado en 2005

Genome-scale RNAi screen for host factors required for HIV replication

artículo científico publicado en 2008

High-throughput cell-based screening using scintillation proximity assay for the discovery of inositol phosphatase inhibitors.

artículo científico publicado en 2004

High-throughput screening of 11beta-hydroxysteroid dehydrogenase type 1 in scintillation proximity assay format

artículo científico publicado en 2005

Hit selection with false discovery rate control in genome-scale RNAi screens

artículo científico publicado en 2008

Identification of metabotropic glutamate receptor antagonists using an automated high-throughput screening system

artículo científico publicado en 2003

Identification of small molecule antagonists of the human mas-related gene-X1 receptor

artículo científico publicado en 2006

Identification of small-molecule modulators of mouse SVZ progenitor cell proliferation and differentiation through high-throughput screening

artículo científico publicado en 2009

Induced pluripotent stem cells — opportunities for disease modelling and drug discovery ⬇️

artículo científico publicado el 11 de noviembre de 2011

Integrating experimental and analytic approaches to improve data quality in genome-wide RNAi screens

artículo científico publicado en 2008

LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease

artículo científico publicado en 2006

Median absolute deviation to improve hit selection for genome-scale RNAi screens

artículo científico publicado en 2008

Miniaturizable homogenous time-resolved fluorescence assay for carboxypeptidase B activity ⬇️

artículo científico publicado el 1 de junio de 2003

Miniaturization and HTS of a FRET-based membrane potential assay for K(ir) channel inhibitors

artículo científico publicado en 2008

Miniaturization and automation of an ubiquitin ligase cascade enzyme-linked immunosorbent assay in 1,536-well format

artículo científico publicado en 2007

Miniaturization of absorbance assays using the fluorescent properties of white microplates

artículo científico publicado en 2005

Miniaturization of intracellular calcium functional assays to 1536-well plate format using a fluorometric imaging plate reader

artículo científico publicado en 2004

Miniaturization of whole live cell-based GPCR assays using microdispensing and detection systems

artículo científico publicado en 2004

Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions

artículo científico publicado en 2006

The use of strictly standardized mean difference for hit selection in primary RNA interference high-throughput screening experiments

artículo científico publicado en 2007

Ultra-high-throughput screening for antagonists of a Gi-coupled receptor in a 2.2-microl 3,456-well plate format cyclicAMP assay

artículo científico publicado en 2007

Lista de obras de

A 1,536-well [(35)S]GTPgammaS scintillation proximity binding assay for ultra-high-throughput screening of an orphan galphai-coupled GPCR.

A 1,536-well ultra-high-throughput siRNA screen to identify regulators of the Wnt/beta-catenin pathway

A 1536-well cAMP assay for Gs- and Gi-coupled receptors using enzyme fragmentation complementation.

A beta-lactamase-dependent Gal4-estrogen receptor beta transactivation assay for the ultra-high throughput screening of estrogen receptor beta agonists in a 3456-well format

A cell-based beta-lactamase reporter gene assay for the identification of inhibitors of hepatitis C virus replication

A cell-based ultra-high-throughput screening assay for identifying inhibitors of D-amino acid oxidase

A collaborative screening program for the discovery of inhibitors of HCV NS2/3 cis-cleaving protease activity

A fluorescence-based thiol quantification assay for ultra-high-throughput screening for inhibitors of coenzyme A production

A fully automated [35S]GTPgammaS scintillation proximity assay for the high-throughput screening of Gi-linked G protein-coupled receptors

A high-precision fluorogenic cholesteryl ester transfer protein assay compatible with animal serum and 3456-well assay technology

A miniaturized cell-based fluorescence resonance energy transfer assay for insulin-receptor activation

A multiplexed siRNA screening strategy to identify genes in the PARP pathway.

A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists

A short-incubation reporter-gene assay for high-throughput screening of estrogen receptor-alpha antagonists

An efficient and fully automated high-throughput transfection method for genome-scale siRNA screens

Application of division arrest technology to cell-based HTS: comparison with frozen and fresh cells

Application of real-time cell electronic sensing (RT-CES) technology to cell-based assays

Compounds that bind APP and inhibit Abeta processing in vitro suggest a novel approach to Alzheimer disease therapeutics

Current trends in high-throughput screening

Development of an intact cell reporter gene beta-lactamase assay for G protein-coupled receptors for high-throughput screening

Development of an oxazolopyridine series of dual thrombin/factor Xa inhibitors via structure-guided lead optimization

Genome-scale RNAi screen for host factors required for HIV replication

High-throughput cell-based screening using scintillation proximity assay for the discovery of inositol phosphatase inhibitors.

High-throughput screening of 11beta-hydroxysteroid dehydrogenase type 1 in scintillation proximity assay format

Hit selection with false discovery rate control in genome-scale RNAi screens

Identification of metabotropic glutamate receptor antagonists using an automated high-throughput screening system

Identification of small molecule antagonists of the human mas-related gene-X1 receptor

Identification of small-molecule modulators of mouse SVZ progenitor cell proliferation and differentiation through high-throughput screening

Induced pluripotent stem cells — opportunities for disease modelling and drug discovery ⬇️

Integrating experimental and analytic approaches to improve data quality in genome-wide RNAi screens

LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease

Median absolute deviation to improve hit selection for genome-scale RNAi screens

Miniaturizable homogenous time-resolved fluorescence assay for carboxypeptidase B activity ⬇️

Miniaturization and HTS of a FRET-based membrane potential assay for K(ir) channel inhibitors

Miniaturization and automation of an ubiquitin ligase cascade enzyme-linked immunosorbent assay in 1,536-well format

Miniaturization of absorbance assays using the fluorescent properties of white microplates

Miniaturization of intracellular calcium functional assays to 1536-well plate format using a fluorometric imaging plate reader

Miniaturization of whole live cell-based GPCR assays using microdispensing and detection systems

Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions

The use of strictly standardized mean difference for hit selection in primary RNA interference high-throughput screening experiments

Ultra-high-throughput screening for antagonists of a Gi-coupled receptor in a 2.2-microl 3,456-well plate format cyclicAMP assay