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A miniaturized technique for assessing protein thermodynamics and function using fast determination of quantitative cysteine reactivity

artículo científico publicado el 5 de enero de 2011

An empirical model for electrostatic interactions in proteins incorporating multiple geometry‐dependent dielectric constants

artículo científico publicado el 15 de mayo de 2003

Analysis of allosteric signal transduction mechanisms in an engineered fluorescent maltose biosensor

artículo científico publicado en 2005

Binding and signaling of surface-immobilized reagentless fluorescent biosensors derived from periplasmic binding proteins

artículo científico publicado en 2006

Computational design of a biologically active enzyme

artículo científico publicado en 2004

Computational design of receptor and sensor proteins with novel functions

artículo científico publicado el 8 de mayo de 2003

Computational design of receptors for an organophosphate surrogate of the nerve agent soman

artículo científico publicado en 2004

Construction of a fluorescent biosensor family

artículo científico publicado en 2002

Construction of new ligand binding sites in proteins of known structure

artículo científico publicado en 1991

Control of a biomolecular motor-powered nanodevice with an engineered chemical switch

artículo científico publicado en 2002

Converting a maltose receptor into a nascent binuclear copper oxygenase by computational design

artículo científico publicado en 2002

Crystal structures of the fungal pathogenAspergillus fumigatusprotein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design

artículo científico publicado en 2014

Describing Complex Structure-Function Relationships in Biomolecules at Equilibrium

scientific article published on 12 January 2020

Design of a calcium-binding protein with desired structure in a cell adhesion molecule

artículo científico publicado en 2005

Engineering key components in a synthetic eukaryotic signal transduction pathway

artículo científico publicado en 2009

Harnessing environmental Ca2+ for extracellular protein thermostabilization

scientific article published on 11 September 2020

Identification of cognate ligands for the Escherichia coli phnD protein product and engineering of a reagentless fluorescent biosensor for phosphonates

artículo científico publicado en 2006

In the wake of two retractions, a request for investigation

scientific article published on 01 July 2008

In this issue

Integration of cell-free protein coexpression with an enzyme-linked immunosorbent assay enables rapid analysis of protein-protein interactions directly from DNA.

artículo científico publicado en 2011

Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I.

artículo científico publicado en 2017

Ligand-induced conformational changes in a thermophilic ribose-binding protein

artículo científico publicado en 2008

Local encoding of computationally designed enzyme activity

artículo científico publicado en 2006

Multifactorial Determinants of Protein Expression in Prokaryotic Open Reading Frames

artículo científico publicado el 18 de agosto de 2010

Orthogonal site-specific protein modification by engineering reversible thiol protection mechanisms

artículo científico publicado en 2004

Periplasmic binding proteins: a versatile superfamily for protein engineering

artículo científico publicado en 2004

Picomole-scale characterization of protein stability and function by quantitative cysteine reactivity

artículo científico publicado en 2010

Programmable ligand detection system in plants through a synthetic signal transduction pathway

artículo científico publicado en 2011

Protein fabrication automation

artículo científico publicado en 2007

Quantitation of protein–protein interactions by thermal stability shift analysis

artículo científico publicado el 11 de julio de 2011

Rational design of a calcium-binding protein

artículo científico publicado en 2003

Retraction

scientific article published on 01 February 2008

Structural Analysis of Semi-specific Oligosaccharide Recognition by a Cellulose-binding Protein of Thermotoga maritima Reveals Adaptations for Functional Diversification of the Oligopeptide Periplasmic Binding Protein Fold

artículo científico publicado en 2009

Structural Analysis of a Periplasmic Binding Protein in the Tripartite ATP-independent Transporter Family Reveals a Tetrameric Assembly That May Have a Role in Ligand Transport

artículo científico publicado en 2008

Structural Factors That Determine Selectivity of a High Fidelity DNA Polymerase for Deoxy-, Dideoxy-, and Ribonucleotides

artículo científico publicado el 30 de mayo de 2012

Structural adaptations that modulate monosaccharide, disaccharide, and trisaccharide specificities in periplasmic maltose-binding proteins

artículo científico publicado en 2009

Structural analysis, identification, and design of calcium-binding sites in proteins

artículo científico publicado en 2002

Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis

artículo científico publicado el 17 de octubre de 2011

Structural reorganization and preorganization in enzyme active sites: comparisons of experimental and theoretically ideal active site geometries in the multistep serine esterase reaction cycle

artículo científico publicado en 2008

Structure-based design of robust glucose biosensors using aThermotoga maritimaperiplasmic glucose-binding protein

artículo científico publicado en 2007

Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens

artículo científico publicado el 4 de agosto de 2011

Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family

artículo científico publicado en 2011

The backbone structure of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein is essentially identical to its mesophilic E. coli homolog

artículo científico publicado en 2008

The crystal structure of a thermophilic glucose binding protein reveals adaptations that interconvert mono and di-saccharide binding sites

artículo científico

Thermodynamic Analysis of Ligand-Induced Changes in Protein Thermal Unfolding Applied to High-Throughput Determination of Ligand Affinities with Extrinsic Fluorescent Dyes

artículo científico publicado el 3 de diciembre de 2010

Visualization of Synaptic Inhibition with an Optogenetic Sensor Developed by Cell-Free Protein Engineering Automation

artículo científico publicado en 2013