Lista de obras -

A novel mechanism for NETosis provides antimicrobial defense at the oral mucosa.

artículo científico publicado en 2015

Alpha-1-antitrypsin is produced by human neutrophil granulocytes and their precursors and liberated during granule exocytosis.

artículo científico publicado en 2011

An ELISA for SGP28/CRISP-3, a cysteine-rich secretory protein in human neutrophils, plasma, and exocrine secretions

artículo científico publicado en 2002

Antimicrobial peptides in innate immune responses.

artículo científico publicado en 2008

Arginase 1 is expressed in myelocytes/metamyelocytes and localized in gelatinase granules of human neutrophils.

artículo científico publicado en 2007

Azurophil granule proteins constitute the major mycobactericidal proteins in human neutrophils and enhance the killing of mycobacteria in macrophages.

artículo científico publicado en 2012

Candida albicans escapes from mouse neutrophils

artículo científico publicado en 2013

Cathelicidins--nature's attempt at combinatorial chemistry.

artículo científico publicado en 2005

Changes in Gene Expression during G-CSF-Induced Emergency Granulopoiesis in Humans.

artículo científico publicado en 2016

Characterization and localization of cysteine-rich secretory protein 3 (CRISP-3) in the human male reproductive tract

artículo científico publicado en 2005

Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients.

artículo científico publicado en 2013

Compound exocytosis of granules in human neutrophils.

artículo científico publicado en 2002

Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma

artículo científico publicado en 2004

Defensin-rich granules of human neutrophils: characterization of secretory properties.

artículo científico publicado en 2002

Derangement of transcription factor profiles during in vitro differentiation of HL60 and NB4 cells

artículo científico publicado en 2006

End-stage differentiation of neutrophil granulocytes in vivo is accompanied by up-regulation of p27kip1 and down-regulation of CDK2, CDK4, and CDK6

artículo científico publicado en 2003

Expression of neutrophil gelatinase-associated lipocalin in skin epidermis

scientific article published on 01 February 2006

Ficolin-1 is present in a highly mobilizable subset of human neutrophil granules and associates with the cell surface after stimulation with fMLP.

artículo científico publicado en 2009

Granulopoiesis and granules of human neutrophils.

artículo científico publicado en 2016

Haptoglobin is synthesized during granulocyte differentiation, stored in specific granules, and released by neutrophils in response to activation.

artículo científico publicado en 2006

Highly glycosylated alpha1-acid glycoprotein is synthesized in myelocytes, stored in secondary granules, and released by activated neutrophils

artículo científico publicado en 2005

Human CRISP-3 binds serum alpha(1)B-glycoprotein across species

scientific article published on 28 January 2010

Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin

artículo científico publicado en 2018

Human α-defensin expression is not dependent on CCAAT/enhancer binding protein-ε in a murine model

artículo científico publicado en 2014

IL-1beta-specific up-regulation of neutrophil gelatinase-associated lipocalin is controlled by IkappaB-zeta

artículo científico publicado en 2006

Identification of human cysteine-rich secretory protein 3 (CRISP-3) as a matrix protein in a subset of peroxidase-negative granules of neutrophils and in the granules of eosinophils

artículo científico publicado en 2002

Identification of the presenilins in hematopoietic cells with localization of presenilin 1 to neutrophil and platelet granules

artículo científico publicado en 2002

Impact of microRNA-130a on the neutrophil proteome

artículo científico publicado en 2015

Induction of neutrophil gelatinase-associated lipocalin expression by co-stimulation with interleukin-17 and tumor necrosis factor-alpha is controlled by IkappaB-zeta but neither by C/EBP-beta nor C/EBP-delta.

artículo científico publicado en 2010

Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis.

artículo científico publicado en 2012

Lipocalin 2 is protective against E. coli pneumonia

artículo científico publicado en 2010

Lipocalin-2 Functions as Inhibitor of Innate Resistance to

Lipocalin-2 from both myeloid cells and the epithelium combats Klebsiella pneumoniae lung infection in mice

artículo científico publicado en 2017

Liver is the major source of elevated serum lipocalin-2 levels after bacterial infection or partial hepatectomy: a critical role for IL-6/STAT3.

artículo científico publicado en 2015

Localization of serglycin in human neutrophil granulocytes and their precursors

artículo científico publicado en 2004

MicroRNA profiling in human neutrophils during bone marrow granulopoiesis and in vivo exudation.

artículo científico publicado en 2013

MicroRNA-130a-mediated down-regulation of Smad4 contributes to reduced sensitivity to TGF-β1 stimulation in granulocytic precursors

artículo científico publicado en 2011

MicroRNA-941 Expression in Polymorphonuclear Granulocytes Is Not Related to Granulomatosis with Polyangiitis

artículo científico publicado en 2016

Microarray-based classification of diffuse large B-cell lymphoma

artículo científico publicado en 2005

Molecular biology diagnostics: malignant lymphoid tumors in adults

artículo científico publicado en 2003

NSP4 Is Stored in Azurophil Granules and Released by Activated Neutrophils as Active Endoprotease with Restricted Specificity ⬇️

artículo científico publicado el 31 de julio de 2013

Neutrophil elastase depends on serglycin proteoglycan for localization in granules

artículo científico publicado en 2007

Neutrophil extracellular traps - the dark side of neutrophils

artículo científico publicado en 2016

Neutrophil gelatinase-associated lipocalin (NGAL/Lcn2) is upregulated in gastric mucosa infected with Helicobacter pylori

artículo científico publicado en 2009

Neutrophil gelatinase-associated lipocalin is a marker for dysregulated keratinocyte differentiation in human skin

artículo científico publicado en 2002

Neutrophil gelatinase-associated lipocalin is up-regulated in human epithelial cells by IL-1 beta, but not by TNF-alpha.

artículo científico publicado en 2003

Neutrophil gelatinase-associated lipocalin, a siderophore-binding eukaryotic protein.

artículo científico publicado en 2006

Neutrophil granules: a library of innate immunity proteins

artículo científico publicado en 2007

No effect of NGAL/lipocalin-2 on aggressiveness of cancer in the MMTV-PyMT/FVB/N mouse model for breast cancer

artículo científico publicado en 2012

Olfactomedin 4 defines a subset of human neutrophils

artículo científico publicado en 2011

On mouse and man: neutrophil gelatinase associated lipocalin is not involved in apoptosis or acute response

artículo científico publicado en 2005

Papillon-Lefèvre syndrome patient reveals species-dependent requirements for neutrophil defenses

artículo científico publicado en 2014

Pharmacogenetics and tailored drug therapy

artículo científico publicado en 2009

Plasma levels of OLFM4 in normals and patients with gastrointestinal cancer

artículo científico publicado en 2015

ProHNPs are the principal α-defensins of human plasma

artículo científico publicado en 2013

Processing of Neutrophil α-Defensins Does Not Rely on Serine Proteases In Vivo

artículo científico publicado en 2015

Processing of seminal plasma hCAP-18 to ALL-38 by gastricsin: a novel mechanism of generating antimicrobial peptides in vagina

artículo científico publicado en 2003

Prodefensins are matrix proteins of specific granules in human neutrophils

artículo científico publicado en 2005

Prognostic significance of metallothionein in B-cell lymphomas

artículo científico publicado en 2006

Protein kinase R mediates intestinal epithelial gene remodeling in response to double-stranded RNA and live rotavirus

artículo científico publicado en 2005

Proteome profiling of human neutrophil granule subsets, secretory vesicles, and cell membrane: correlation with transcriptome profiling of neutrophil precursors.

artículo científico publicado en 2013

Research update for articles published in EJCI in 2013.

artículo científico publicado en 2015

Serglycin participates in retention of α-defensin in granules during myelopoiesis

artículo científico publicado en 2011

Serglycin proteoglycan is not implicated in localizing exocrine pancreas enzymes to zymogen granules.

artículo científico publicado en 2009

Systems biology of neutrophil differentiation and immune response.

artículo científico publicado en 2005

Technical advance: immunophenotypical characterization of human neutrophil differentiation.

artículo científico publicado en 2011

Tethering of Ficolin-1 to cell surfaces through recognition of sialic acid by the fibrinogen-like domain

artículo científico publicado en 2010

The Ficolins

artículo científico publicado en 2009

The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor.

artículo científico publicado en 2003

The cathelicidin anti-microbial peptide LL-37 is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer epithelium

scientific article published on 01 March 2003

The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptake

scientific journal article

The genetics of ficolins

artículo científico publicado en 2009

The in vivo profile of transcription factors during neutrophil differentiation in human bone marrow

artículo científico publicado en 2003

The innate pattern recognition molecule Ficolin-1 is secreted by monocytes/macrophages and is circulating in human plasma

artículo científico publicado en 2008

The secretory leukocyte protease inhibitor (SLPI) and the secondary granule protein lactoferrin are synthesized in myelocytes, colocalize in subcellular fractions of neutrophils, and are coreleased by activated neutrophils

artículo científico publicado en 2008

The transcriptional activation program of human neutrophils in skin lesions supports their important role in wound healing.

artículo científico publicado en 2004

The transcriptional program of terminal granulocytic differentiation

artículo científico publicado en 2004

Tissue expression of copines and isolation of copines I and III from the cytosol of human neutrophils

artículo científico publicado en 2003

Vitamin d-directed rheostatic regulation of monocyte antibacterial responses

artículo científico publicado en 2009

Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors

artículo científico publicado en 2003

beta-Microseminoprotein binds CRISP-3 in human seminal plasma

artículo científico publicado en 2005

miRNA-130a regulates C/EBP-ε expression during granulopoiesis.

artículo científico publicado en 2014

Lista de obras de

A novel mechanism for NETosis provides antimicrobial defense at the oral mucosa.

Alpha-1-antitrypsin is produced by human neutrophil granulocytes and their precursors and liberated during granule exocytosis.

An ELISA for SGP28/CRISP-3, a cysteine-rich secretory protein in human neutrophils, plasma, and exocrine secretions

Antimicrobial peptides in innate immune responses.

Arginase 1 is expressed in myelocytes/metamyelocytes and localized in gelatinase granules of human neutrophils.

Azurophil granule proteins constitute the major mycobactericidal proteins in human neutrophils and enhance the killing of mycobacteria in macrophages.

Candida albicans escapes from mouse neutrophils

Cathelicidins--nature's attempt at combinatorial chemistry.

Changes in Gene Expression during G-CSF-Induced Emergency Granulopoiesis in Humans.

Characterization and localization of cysteine-rich secretory protein 3 (CRISP-3) in the human male reproductive tract

Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients.

Compound exocytosis of granules in human neutrophils.

Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma

Defensin-rich granules of human neutrophils: characterization of secretory properties.

Derangement of transcription factor profiles during in vitro differentiation of HL60 and NB4 cells

End-stage differentiation of neutrophil granulocytes in vivo is accompanied by up-regulation of p27kip1 and down-regulation of CDK2, CDK4, and CDK6

Expression of neutrophil gelatinase-associated lipocalin in skin epidermis

Ficolin-1 is present in a highly mobilizable subset of human neutrophil granules and associates with the cell surface after stimulation with fMLP.

Granulopoiesis and granules of human neutrophils.

Haptoglobin is synthesized during granulocyte differentiation, stored in specific granules, and released by neutrophils in response to activation.

Highly glycosylated alpha1-acid glycoprotein is synthesized in myelocytes, stored in secondary granules, and released by activated neutrophils

Human CRISP-3 binds serum alpha(1)B-glycoprotein across species

Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin

Human α-defensin expression is not dependent on CCAAT/enhancer binding protein-ε in a murine model

IL-1beta-specific up-regulation of neutrophil gelatinase-associated lipocalin is controlled by IkappaB-zeta

Identification of human cysteine-rich secretory protein 3 (CRISP-3) as a matrix protein in a subset of peroxidase-negative granules of neutrophils and in the granules of eosinophils

Identification of the presenilins in hematopoietic cells with localization of presenilin 1 to neutrophil and platelet granules

Impact of microRNA-130a on the neutrophil proteome

Induction of neutrophil gelatinase-associated lipocalin expression by co-stimulation with interleukin-17 and tumor necrosis factor-alpha is controlled by IkappaB-zeta but neither by C/EBP-beta nor C/EBP-delta.

Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis.

Lipocalin 2 is protective against E. coli pneumonia

Lipocalin-2 Functions as Inhibitor of Innate Resistance to

Lipocalin-2 from both myeloid cells and the epithelium combats Klebsiella pneumoniae lung infection in mice

Liver is the major source of elevated serum lipocalin-2 levels after bacterial infection or partial hepatectomy: a critical role for IL-6/STAT3.

Localization of serglycin in human neutrophil granulocytes and their precursors

MicroRNA profiling in human neutrophils during bone marrow granulopoiesis and in vivo exudation.

MicroRNA-130a-mediated down-regulation of Smad4 contributes to reduced sensitivity to TGF-β1 stimulation in granulocytic precursors

MicroRNA-941 Expression in Polymorphonuclear Granulocytes Is Not Related to Granulomatosis with Polyangiitis

Microarray-based classification of diffuse large B-cell lymphoma

Molecular biology diagnostics: malignant lymphoid tumors in adults

NSP4 Is Stored in Azurophil Granules and Released by Activated Neutrophils as Active Endoprotease with Restricted Specificity ⬇️

Neutrophil elastase depends on serglycin proteoglycan for localization in granules

Neutrophil extracellular traps - the dark side of neutrophils

Neutrophil gelatinase-associated lipocalin (NGAL/Lcn2) is upregulated in gastric mucosa infected with Helicobacter pylori

Neutrophil gelatinase-associated lipocalin is a marker for dysregulated keratinocyte differentiation in human skin

Neutrophil gelatinase-associated lipocalin is up-regulated in human epithelial cells by IL-1 beta, but not by TNF-alpha.

Neutrophil gelatinase-associated lipocalin, a siderophore-binding eukaryotic protein.

Neutrophil granules: a library of innate immunity proteins

No effect of NGAL/lipocalin-2 on aggressiveness of cancer in the MMTV-PyMT/FVB/N mouse model for breast cancer

Olfactomedin 4 defines a subset of human neutrophils

On mouse and man: neutrophil gelatinase associated lipocalin is not involved in apoptosis or acute response

Papillon-Lefèvre syndrome patient reveals species-dependent requirements for neutrophil defenses

Pharmacogenetics and tailored drug therapy

Plasma levels of OLFM4 in normals and patients with gastrointestinal cancer

ProHNPs are the principal α-defensins of human plasma

Processing of Neutrophil α-Defensins Does Not Rely on Serine Proteases In Vivo

Processing of seminal plasma hCAP-18 to ALL-38 by gastricsin: a novel mechanism of generating antimicrobial peptides in vagina

Prodefensins are matrix proteins of specific granules in human neutrophils

Prognostic significance of metallothionein in B-cell lymphomas

Protein kinase R mediates intestinal epithelial gene remodeling in response to double-stranded RNA and live rotavirus

Proteome profiling of human neutrophil granule subsets, secretory vesicles, and cell membrane: correlation with transcriptome profiling of neutrophil precursors.

Research update for articles published in EJCI in 2013.

Serglycin participates in retention of α-defensin in granules during myelopoiesis

Serglycin proteoglycan is not implicated in localizing exocrine pancreas enzymes to zymogen granules.

Systems biology of neutrophil differentiation and immune response.

Technical advance: immunophenotypical characterization of human neutrophil differentiation.

Tethering of Ficolin-1 to cell surfaces through recognition of sialic acid by the fibrinogen-like domain

The Ficolins

The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor.

The cathelicidin anti-microbial peptide LL-37 is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer epithelium

The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptake

The genetics of ficolins

The in vivo profile of transcription factors during neutrophil differentiation in human bone marrow

The innate pattern recognition molecule Ficolin-1 is secreted by monocytes/macrophages and is circulating in human plasma

The secretory leukocyte protease inhibitor (SLPI) and the secondary granule protein lactoferrin are synthesized in myelocytes, colocalize in subcellular fractions of neutrophils, and are coreleased by activated neutrophils

The transcriptional activation program of human neutrophils in skin lesions supports their important role in wound healing.

The transcriptional program of terminal granulocytic differentiation

Tissue expression of copines and isolation of copines I and III from the cytosol of human neutrophils

Vitamin d-directed rheostatic regulation of monocyte antibacterial responses