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3,3'-Diindolylmethane induces G1 arrest and apoptosis in human acute T-cell lymphoblastic leukemia cells

artículo científico publicado en 2012

3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells

artículo científico publicado en 2012

A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat.

artículo científico publicado en 2017

A role for low-abundance miRNAs in colon cancer: the miR-206/Krüppel-like factor 4 (KLF4) axis

artículo científico publicado el 24 de septiembre de 2012

Absorption and chemopreventive targets of sulforaphane in humans following consumption of broccoli sprouts or a myrosinase-treated broccoli sprout extract.

artículo científico publicado en 2015

Acetylation of CCAR2 Establishes a BET/BRD9 Acetyl Switch in Response to Combined Deacetylase and Bromodomain Inhibition

scientific article published on 14 January 2019

Analysis of autophagic flux in response to sulforaphane in metastatic prostate cancer cells.

artículo científico publicado en 2015

Assessment of global proteome in LNCaP cells by 2D-RP/RP LC-MS/MS following sulforaphane exposure.

artículo científico publicado en 2015

Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.

artículo científico publicado en 2016

Dietary HDAC inhibitors: time to rethink weak ligands in cancer chemoprevention?

artículo científico publicado en 2005

Dietary agents as histone deacetylase inhibitors

artículo científico publicado en 2006

Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates

artículo científico publicado en 2008

Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells

artículo científico publicado el 26 de octubre de 2011

Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention

artículo científico publicado en 2009

Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells

artículo científico publicado en 2011

Differential modulation of dibenzo[def,p]chrysene transplacental carcinogenesis: maternal diets rich in indole-3-carbinol versus sulforaphane

artículo científico publicado en 2013

Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors

artículo científico publicado en 2017

Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells

scientific article published on 22 January 2014

Epigenetic Regulation by Sulforaphane: Opportunities for Breast and Prostate Cancer Chemoprevention

artículo científico publicado en 2015

Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer

artículo científico publicado en 2012

HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates

artículo científico publicado en 2013

HDAC6 activity is not required for basal autophagic flux in metastatic prostate cancer cells

artículo científico publicado en 2015

Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors

artículo científico

Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly

artículo científico publicado el 30 de mayo de 2011

Metabolism and tissue distribution of sulforaphane in Nrf2 knockout and wild-type mice

artículo científico publicado en 2011

Metabolism as a key to histone deacetylase inhibition

artículo científico publicado en 2011

MicroRNA profiling of carcinogen‐induced rat colon tumors and the influence of dietary spinach

artículo científico publicado el 29 de mayo de 2012

MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals

artículo científico publicado en 2011

Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds

artículo científico publicado en 2009

Multi-targeted prevention of cancer by sulforaphane

artículo científico publicado en 2008

Phytochemicals from cruciferous vegetables, epigenetics, and prostate cancer prevention

artículo científico publicado en 2013

Promoter de-methylation of cyclin D2 by sulforaphane in prostate cancer cells

artículo científico publicado el 26 de octubre de 2011

Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells

artículo científico publicado en 2005

Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice

artículo científico publicado en 2006

Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects.

artículo científico publicado en 2007

The epigenome as a potential mediator of cancer and disease prevention in prenatal development

artículo científico publicado en 2013

The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.

artículo científico publicado en 2017

Untargeted Metabolomic Screen Reveals Changes in Human Plasma Metabolite Profiles Following Consumption of Fresh Broccoli Sprouts.

artículo científico publicado en 2018