Lista de obras -

A bioluminescence imaging based in vivo model for preclinical testing of novel cellular immunotherapy strategies to improve the graft-versus-myeloma effect.

artículo científico publicado en 2008

A class II-restricted cytotoxic T-cell clone recognizes a human minor histocompatibility antigen with a restricted tissue distribution.

artículo científico publicado en 2005

A dominant activating RAC2 variant associated with immunodeficiency and pulmonary disease

artículo científico publicado en 2019

A novel flow cytometric assay for the quantification of adhesion of subsets within a heterogeneous cell population; analysis of lymphocyte function-associated antigen-1 (LFA-1)-mediated binding of bone marrow-derived primary tumour cells of patients

scientific article published on 01 September 1993

Adhesion molecules: a new target for immunoliposome-mediated drug delivery

artículo científico publicado en 1995

Adhesion of subsets of human blood mononuclear cells to endothelial cells in vitro, as quantified by flow cytometry

scientific article published on 01 December 1992

All-printed cell counting chambers with on-chip sample preparation for point-of-care CD4 counting

scientific article published on 03 July 2018

Antigens shared by malignant plasma cells and normal B cells may be involved in graft versus myeloma

artículo científico publicado en 2003

Anti‐adhesive signals are mediated via major histocompatibility complex class II molecules in normal and neoplastic human B cells: Correlation with B cell differentiation stage ⬇️

artículo científico publicado el 1 de octubre de 1997

Association of IgM monoclonal gammopathy with progressive muscular atrophy and multifocal motor neuropathy: a case-control study

artículo científico publicado en 2015

CD27 deficiency is associated with combined immunodeficiency and persistent symptomatic EBV viremia

artículo científico publicado en 2011

CD38 expression and complement inhibitors affect response and resistance to daratumumab therapy in myeloma

artículo científico publicado en 2016

CD44 isoforms are differentially regulated in plasma cell dyscrasias and CD44v9 represents a new independent prognostic parameter in multiple myeloma

scientific article published on 01 December 2001

CD44 isoforms distinguish between bone marrow plasma cells from normal individuals and patients with multiple myeloma at different stages of disease

artículo científico publicado en 1998

CD44 variant isoforms are involved in plasma cell adhesion to bone marrow stromal cells

artículo científico publicado en 2002

CT screening for pulmonary pathology in common variable immunodeficiency disorders and the correlation with clinical and immunological parameters

artículo científico publicado en 2014

Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients

scientific article published on 15 March 2018

Changes in lymphocyte subsets in workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

Chemosensitization of myeloma plasma cells by an antisense-mediated downregulation of Bcl-2 protein

artículo científico publicado en 2003

Co-ligation of ICAM-1 (CD54) and membrane IgM negatively affects B cell receptor signaling

artículo científico publicado en 1995

Consensus strategy to quantitate malignant cells in myeloma patients is validated in a multicenter study. Belgium-Dutch Hematology-Oncology Group

artículo científico publicado en 2000

Continuous low-dose cyclophosphamide-prednisone is effective and well tolerated in patients with advanced multiple myeloma

artículo científico publicado en 2001

Cytogenetic aberrations in neuropathy associated with IgM monoclonal gammopathy

scientific article published on 01 June 2007

Defective calcium signaling and disrupted CD20-B-cell receptor dissociation in patients with common variable immunodeficiency disorders.

artículo científico publicado en 2011

Detection of choroid- and retina-antigen reactive CD8(+) and CD4(+) T lymphocytes in the vitreous fluid of patients with birdshot chorioretinopathy

artículo científico publicado en 2014

Different CD44 splicing patterns define prognostic subgroups in multiple myeloma

artículo científico publicado en 1996

Domain 5 of the intercellular adhesion molecule-1 (ICAM-1) is involved in adhesion of B-cells and follicular dendritic cells

artículo científico publicado en 1994

Donor leukocyte infusions inducing remissions repeatedly in a patient with recurrent multiple myeloma after allogeneic bone marrow transplantation

artículo científico publicado en 1999

Dose-finding study of high-dose simvastatin combined with standard chemotherapy in patients with relapsed or refractory myeloma or lymphoma.

artículo científico publicado en 2006

Effect of antithymocyte globulin on quantitative immune recovery and graft-versus-host disease after partially T-cell-depleted bone marrow transplantation: a comparison between recipients of matched related and matched unrelated donor grafts.

artículo científico publicado en 2003

Effect of daratumumab on normal plasma cells, polyclonal immunoglobulin levels, and vaccination responses in extensively pre-treated multiple myeloma patients

artículo científico publicado en 2019

Eradication of medullary multiple myeloma by CD4+ cytotoxic human T lymphocytes directed at a single minor histocompatibility antigen

scientific article published on 09 November 2010

Establishing human leukemia xenograft mouse models by implanting human bone marrow-like scaffold-based niches

artículo científico publicado en 2016

Expression of members of the immunoglobulin VH3 gene families is not restricted at the level of individual genes in human chronic lymphocytic leukemia

artículo científico publicado el 1 de marzo de 1992

Functional involvement of CD44, a family of cell adhesion molecules, in immune responses, tumour progression and haematopoiesis.

artículo científico publicado en 1998

Functional properties of human B cell subpopulations defined by monoclonal antibodies HB4 and FMC7

artículo científico publicado en 1988

G3139, a Bcl-2 antisense oligodeoxynucleotide, induces clinical responses in VAD refractory myeloma

artículo científico publicado en 2004

Gene-expression profiling of CD34+ cells from various hematopoietic stem-cell sources reveals functional differences in stem-cell activity

artículo científico publicado en 2003

Geranylgeranylated proteins are involved in the regulation of myeloma cell growth.

artículo científico publicado en 2005

Graft versus myeloma may overcome the unfavorable effect of deletion of chromosome 13 in multiple myeloma

artículo científico publicado en 2003

Growth factors and antiapoptotic signaling pathways in multiple myeloma

artículo científico publicado en 2005

High dose simvastatin does not reverse resistance to vincristine, adriamycin, and dexamethasone (VAD) in myeloma

artículo científico publicado en 2007

Host cell membrane proteins on human immunodeficiency virus type 1 after in vitro infection of H9 cells and blood mononuclear cells. An immuno-electron microscopic study

artículo científico publicado en 1993

Human follicular dendritic cells: isolation and characteristics in situ and in suspension

artículo científico publicado en 1991

Idarubicin overcomes P-glycoprotein-related multidrug resistance: comparison with doxorubicin and daunorubicin in human multiple myeloma cell lines

artículo científico publicado en 1999

Illegitimate WNT signaling promotes proliferation of multiple myeloma cells

artículo científico publicado en 2004

Immune reconstitution in children following chemotherapy for haematological malignancies: a long-term follow-up

artículo científico publicado en 2010

Immunoglobulin gene analysis in polyneuropathy associated with IgM monoclonal gammopathy

scientific article published on 06 March 2006

Immunoglobulin production by human peripheral lymphocytes induced by anti-C3 receptor antibodies ⬇️

artículo científico publicado el 1 de marzo de 1984

Impact of treatment reduction for childhood acute lymphoblastic leukemia on serum immunoglobulins and antibodies against vaccine-preventable diseases

artículo científico publicado en 2011

Inability of a monoclonal anti-light chain antibody to detect clonal plasma cells in a patient with multiple myeloma by multicolor flow cytometry

artículo científico publicado en 2012

Inability of monoclonal anti-light chain antibody to detect clonal B-cells in a patient with follicular lymphoma by multicolor flow cytometry.

artículo científico publicado en 2014

Inhibition of protein geranylgeranylation induces apoptosis in myeloma plasma cells by reducing Mcl-1 protein levels

artículo científico publicado en 2003

Inhibition of the mevalonate pathway potentiates the effects of lenalidomide in myeloma

artículo científico publicado en 2008

Lenalidomide combined with low-dose cyclophosphamide and prednisone modulates Ikaros and Aiolos in lymphocytes, resulting in immunostimulatory effects in lenalidomide-refractory multiple myeloma patients

Lethal neonatal bone marrow failure syndrome with multiple congenital abnormalities including limb defects due to a constitutional deletion of 3' MECOM.

artículo científico publicado en 2018

Ligands of surface Ig raise cytoplasmic free Ca++ in human B cells

artículo científico publicado en 1985

Long-term bone marrow cultured stromal cells regulate myeloma tumour growth in vitro: studies with primary tumour cells and LTBMC-dependent cell lines

artículo científico publicado en 1998

Lung-resistance-related protein expression is a negative predictive factor for response to conventional low but not to intensified dose alkylating chemotherapy in multiple myeloma

artículo científico publicado en 1998

Lymphoblastic lymphoma with a triple-hit profile: a rare but distinct and relevant entity.

artículo científico publicado en 2016

Lymphocyte characteristics in children with common variable immunodeficiency

artículo científico publicado en 2009

Lymphocyte function-associated antigen-1 expression on plasma cells correlates with tumor growth in multiple myeloma

artículo científico publicado en 1992

Malignant transformation of monoclonal gammopathy of undetermined significance: cumulative incidence and prognostic factors.

artículo científico publicado en 2001

Measurement of pneumococcal polysaccharide vaccine responses for immunodeficiency diagnostics: combined IgG responses compared to serotype specific IgG responses.

artículo científico publicado en 2013

Mitogenic stimulation of malignant B cells CLL: diminished in-vitro stimulation with anti-CR1 antibodies

scientific article published on 01 January 1988

Mitogenic stimulation of malignant B cells Waldenstrøm's macroglobulinaemia: secretion of monoclonal IgM by in vitro-induced plasmablasts

scientific article published on 01 January 1986

Mitogenic stimulation of malignant B cells. Chronic lymphocytic leukaemia: relationship between stimulation and surface phenotype

scientific article published on 01 November 1982

Mitogenic stimulation of malignant B cells. Chronic lymphocytic leukaemia: secretion of monoclonal IgM by in vitro-induced plasmablasts

artículo científico publicado en 1984

Monocytes and Granulocytes Reduce CD38 Expression Levels on Myeloma Cells in Patients Treated with Daratumumab

artículo científico publicado en 2017

Multiple ICAM-1 (CD54) epitopes are involved in homotypic B-cell adhesion

artículo científico publicado el 1 de mayo de 1992

New treatment strategies for multiple myeloma by targeting BCL-2 and the mevalonate pathway

artículo científico publicado en 2006

Novel data analysis method for multicolour flow cytometry links variability of multiple markers on single cells to a clinical phenotype.

artículo científico

Phase 1/2 study of lenalidomide combined with low-dose cyclophosphamide and prednisone in lenalidomide-refractory multiple myeloma

artículo científico publicado en 2016

Phase I/II study of sequential chemoimmunotherapy (SCIT) for metastatic melanoma: outpatient treatment with dacarbazine, granulocyte-macrophage colony-stimulating factor, low-dose interleukin-2, and interferon-alpha

artículo científico publicado en 2002

Phenotypical and functional characterization of the idiotype-positive blood B cells in multiple myeloma

artículo científico publicado en 1988

Primary tumor cells of myeloma patients induce interleukin-6 secretion in long-term bone marrow cultures

artículo científico publicado en 1994

Protein geranylgeranylation is critical for the regulation of survival and proliferation of lymphoma tumor cells

artículo científico publicado en 2003

Rapid identification of clinical relevant minor histocompatibility antigens via genome-wide zygosity-genotype correlation analysis

artículo científico publicado en 2009

Rebuilding human leukocyte antigen class II-restricted minor histocompatibility antigen specificity in recall antigen-specific T cells by adoptive T cell receptor transfer: implications for adoptive immunotherapy.

artículo científico publicado en 2007

Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma

Reduced versus intensive chemotherapy for childhood acute lymphoblastic leukemia: impact on lymphocyte compartment composition

artículo científico publicado en 2010

Salivary immune responses to the 7-valent pneumococcal conjugate vaccine in the first 2 years of life

artículo científico publicado en 2012

Selective in vitro expansion and efficient retroviral transduction of human CD34+ CD38- haematopoietic stem cells

artículo científico publicado en 2002

Splenic TFH expansion participates in B-cell differentiation and antiplatelet-antibody production during immune thrombocytopenia.

artículo científico publicado en 2014

Susceptibility of malignant plasma cells to HA-1(H) specific lysis suggests a role for the minor histocompatibility antigen HA-1 in the graft-versus-myeloma effect

artículo científico publicado en 2004

Synergy in B-Cell Activation between Toll-Like Receptor 9 and Transmembrane Activator and Calcium-Modulating Cyclophilin Ligand Interactor (TACI) in A181E/C104R Compound Heterozygous Siblings

T cells in B cell chronic lymphocytic leukaemia. I. Decreased frequency of T lymphocytes secreting suppressor factor

scientific article published on 01 January 1986

T cells in B cell chronic lymphocytic leukemia. II. Lack of antigen-specific T suppressor cells and their progenitors

artículo científico publicado en 1985

The SCID mouse as a model for multiple myeloma

artículo científico publicado en 1995

The cholesterol lowering drug lovastatin induces cell death in myeloma plasma cells

artículo científico publicado en 2002

The hepatocyte growth factor/Met pathway controls proliferation and apoptosis in multiple myeloma.

artículo científico publicado en 2003

Toward targeting B cell cancers with CD4+ CTLs: identification of a CD19-encoded minor histocompatibility antigen using a novel genome-wide analysis

artículo científico publicado en 2008

Upregulation of CD38 expression on multiple myeloma cells by all-trans retinoic acid improves the efficacy of daratumumab.

artículo científico publicado en 2015

Lista de obras de

A bioluminescence imaging based in vivo model for preclinical testing of novel cellular immunotherapy strategies to improve the graft-versus-myeloma effect.

A class II-restricted cytotoxic T-cell clone recognizes a human minor histocompatibility antigen with a restricted tissue distribution.

A dominant activating RAC2 variant associated with immunodeficiency and pulmonary disease

A novel flow cytometric assay for the quantification of adhesion of subsets within a heterogeneous cell population; analysis of lymphocyte function-associated antigen-1 (LFA-1)-mediated binding of bone marrow-derived primary tumour cells of patients

Adhesion molecules: a new target for immunoliposome-mediated drug delivery

Adhesion of subsets of human blood mononuclear cells to endothelial cells in vitro, as quantified by flow cytometry

All-printed cell counting chambers with on-chip sample preparation for point-of-care CD4 counting

Antigens shared by malignant plasma cells and normal B cells may be involved in graft versus myeloma

Anti‐adhesive signals are mediated via major histocompatibility complex class II molecules in normal and neoplastic human B cells: Correlation with B cell differentiation stage ⬇️

Association of IgM monoclonal gammopathy with progressive muscular atrophy and multifocal motor neuropathy: a case-control study

CD27 deficiency is associated with combined immunodeficiency and persistent symptomatic EBV viremia

CD38 expression and complement inhibitors affect response and resistance to daratumumab therapy in myeloma

CD44 isoforms are differentially regulated in plasma cell dyscrasias and CD44v9 represents a new independent prognostic parameter in multiple myeloma

CD44 isoforms distinguish between bone marrow plasma cells from normal individuals and patients with multiple myeloma at different stages of disease

CD44 variant isoforms are involved in plasma cell adhesion to bone marrow stromal cells

CT screening for pulmonary pathology in common variable immunodeficiency disorders and the correlation with clinical and immunological parameters

Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients

Changes in lymphocyte subsets in workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

Chemosensitization of myeloma plasma cells by an antisense-mediated downregulation of Bcl-2 protein

Co-ligation of ICAM-1 (CD54) and membrane IgM negatively affects B cell receptor signaling

Consensus strategy to quantitate malignant cells in myeloma patients is validated in a multicenter study. Belgium-Dutch Hematology-Oncology Group

Continuous low-dose cyclophosphamide-prednisone is effective and well tolerated in patients with advanced multiple myeloma

Cytogenetic aberrations in neuropathy associated with IgM monoclonal gammopathy

Defective calcium signaling and disrupted CD20-B-cell receptor dissociation in patients with common variable immunodeficiency disorders.

Detection of choroid- and retina-antigen reactive CD8(+) and CD4(+) T lymphocytes in the vitreous fluid of patients with birdshot chorioretinopathy

Different CD44 splicing patterns define prognostic subgroups in multiple myeloma

Domain 5 of the intercellular adhesion molecule-1 (ICAM-1) is involved in adhesion of B-cells and follicular dendritic cells

Donor leukocyte infusions inducing remissions repeatedly in a patient with recurrent multiple myeloma after allogeneic bone marrow transplantation

Dose-finding study of high-dose simvastatin combined with standard chemotherapy in patients with relapsed or refractory myeloma or lymphoma.

Effect of antithymocyte globulin on quantitative immune recovery and graft-versus-host disease after partially T-cell-depleted bone marrow transplantation: a comparison between recipients of matched related and matched unrelated donor grafts.

Effect of daratumumab on normal plasma cells, polyclonal immunoglobulin levels, and vaccination responses in extensively pre-treated multiple myeloma patients

Eradication of medullary multiple myeloma by CD4+ cytotoxic human T lymphocytes directed at a single minor histocompatibility antigen

Establishing human leukemia xenograft mouse models by implanting human bone marrow-like scaffold-based niches

Expression of members of the immunoglobulin VH3 gene families is not restricted at the level of individual genes in human chronic lymphocytic leukemia

Functional involvement of CD44, a family of cell adhesion molecules, in immune responses, tumour progression and haematopoiesis.

Functional properties of human B cell subpopulations defined by monoclonal antibodies HB4 and FMC7

G3139, a Bcl-2 antisense oligodeoxynucleotide, induces clinical responses in VAD refractory myeloma

Gene-expression profiling of CD34+ cells from various hematopoietic stem-cell sources reveals functional differences in stem-cell activity

Geranylgeranylated proteins are involved in the regulation of myeloma cell growth.

Graft versus myeloma may overcome the unfavorable effect of deletion of chromosome 13 in multiple myeloma

Growth factors and antiapoptotic signaling pathways in multiple myeloma

High dose simvastatin does not reverse resistance to vincristine, adriamycin, and dexamethasone (VAD) in myeloma

Host cell membrane proteins on human immunodeficiency virus type 1 after in vitro infection of H9 cells and blood mononuclear cells. An immuno-electron microscopic study

Human follicular dendritic cells: isolation and characteristics in situ and in suspension

Idarubicin overcomes P-glycoprotein-related multidrug resistance: comparison with doxorubicin and daunorubicin in human multiple myeloma cell lines

Illegitimate WNT signaling promotes proliferation of multiple myeloma cells

Immune reconstitution in children following chemotherapy for haematological malignancies: a long-term follow-up

Immunoglobulin gene analysis in polyneuropathy associated with IgM monoclonal gammopathy

Immunoglobulin production by human peripheral lymphocytes induced by anti-C3 receptor antibodies ⬇️

Impact of treatment reduction for childhood acute lymphoblastic leukemia on serum immunoglobulins and antibodies against vaccine-preventable diseases

Inability of a monoclonal anti-light chain antibody to detect clonal plasma cells in a patient with multiple myeloma by multicolor flow cytometry

Inability of monoclonal anti-light chain antibody to detect clonal B-cells in a patient with follicular lymphoma by multicolor flow cytometry.

Inhibition of protein geranylgeranylation induces apoptosis in myeloma plasma cells by reducing Mcl-1 protein levels

Inhibition of the mevalonate pathway potentiates the effects of lenalidomide in myeloma

Lenalidomide combined with low-dose cyclophosphamide and prednisone modulates Ikaros and Aiolos in lymphocytes, resulting in immunostimulatory effects in lenalidomide-refractory multiple myeloma patients

Lethal neonatal bone marrow failure syndrome with multiple congenital abnormalities including limb defects due to a constitutional deletion of 3' MECOM.

Ligands of surface Ig raise cytoplasmic free Ca++ in human B cells

Long-term bone marrow cultured stromal cells regulate myeloma tumour growth in vitro: studies with primary tumour cells and LTBMC-dependent cell lines

Lung-resistance-related protein expression is a negative predictive factor for response to conventional low but not to intensified dose alkylating chemotherapy in multiple myeloma

Lymphoblastic lymphoma with a triple-hit profile: a rare but distinct and relevant entity.

Lymphocyte characteristics in children with common variable immunodeficiency

Lymphocyte function-associated antigen-1 expression on plasma cells correlates with tumor growth in multiple myeloma

Malignant transformation of monoclonal gammopathy of undetermined significance: cumulative incidence and prognostic factors.

Measurement of pneumococcal polysaccharide vaccine responses for immunodeficiency diagnostics: combined IgG responses compared to serotype specific IgG responses.

Mitogenic stimulation of malignant B cells CLL: diminished in-vitro stimulation with anti-CR1 antibodies

Mitogenic stimulation of malignant B cells Waldenstrøm's macroglobulinaemia: secretion of monoclonal IgM by in vitro-induced plasmablasts

Mitogenic stimulation of malignant B cells. Chronic lymphocytic leukaemia: relationship between stimulation and surface phenotype

Mitogenic stimulation of malignant B cells. Chronic lymphocytic leukaemia: secretion of monoclonal IgM by in vitro-induced plasmablasts

Monocytes and Granulocytes Reduce CD38 Expression Levels on Myeloma Cells in Patients Treated with Daratumumab

Multiple ICAM-1 (CD54) epitopes are involved in homotypic B-cell adhesion

New treatment strategies for multiple myeloma by targeting BCL-2 and the mevalonate pathway

Novel data analysis method for multicolour flow cytometry links variability of multiple markers on single cells to a clinical phenotype.

Phase 1/2 study of lenalidomide combined with low-dose cyclophosphamide and prednisone in lenalidomide-refractory multiple myeloma

Phase I/II study of sequential chemoimmunotherapy (SCIT) for metastatic melanoma: outpatient treatment with dacarbazine, granulocyte-macrophage colony-stimulating factor, low-dose interleukin-2, and interferon-alpha

Phenotypical and functional characterization of the idiotype-positive blood B cells in multiple myeloma

Primary tumor cells of myeloma patients induce interleukin-6 secretion in long-term bone marrow cultures

Protein geranylgeranylation is critical for the regulation of survival and proliferation of lymphoma tumor cells

Rapid identification of clinical relevant minor histocompatibility antigens via genome-wide zygosity-genotype correlation analysis

Rebuilding human leukocyte antigen class II-restricted minor histocompatibility antigen specificity in recall antigen-specific T cells by adoptive T cell receptor transfer: implications for adoptive immunotherapy.