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2B and 2C mutations are essential but mutations throughout the genome of HAV contribute to adaptation to cell culture

scientific article published on 01 June 1993

A bicistronic subgenomic mRNA encodes both the ORF2 and ORF3 proteins of hepatitis E virus

artículo científico publicado en 2006

A hepatitis A virus deletion mutant which lacks the first pyrimidine-rich tract of the 5' nontranslated RNA remains virulent in primates after direct intrahepatic nucleic acid transfection

artículo científico publicado en 1995

A hydrophobic heptad repeat of the core protein of woodchuck hepatitis virus is required for capsid assembly

artículo científico publicado en 1996

A naturally occurring human/hepatitis E recombinant virus predominates in serum but not in faeces of a chronic hepatitis E patient and has a growth advantage in cell culture

artículo científico publicado en 2011

A new Chinese isolate of hepatitis E virus: comparison with strains recovered from different geographical regions

artículo científico publicado en 1994

A novel virus in swine is closely related to the human hepatitis E virus ⬇️

artículo científico publicado el 2 de septiembre de 1997

A polymerase-chain reaction-based assay for serum HDV RNA.

artículo científico publicado en 1991

A simian strain of hepatitis A virus, AGM-27, functions as an attenuated vaccine for chimpanzees

artículo científico publicado en 1996

A truncated ORF2 protein contains the most immunogenic site on ORF2: antibody responses to non-vaccine sequences following challenge of vaccinated and non-vaccinated macaques with hepatitis E virus

artículo científico publicado en 2005

A virus discovery method incorporating DNase treatment and its application to the identification of two bovine parvovirus species

artículo científico publicado en 2001

Active surveillance for acute viral hepatitis in rural villages in the Nile Delta

artículo científico publicado en 2006

Acute hepatitis E infection accounts for some cases of suspected drug-induced liver injury

artículo científico publicado en 2011

Acute hepatitis caused by a novel strain of hepatitis E virus most closely related to United States strains

artículo científico publicado en 2001

Acute viral hepatitis in Saudi Arabia: seroepidemiological analysis, risk factors, clinical manifestations, and evidence for a sixth hepatitis agent

artículo científico publicado en 1995

Adaptation of a genotype 3 hepatitis E virus to efficient growth in cell culture depends on an inserted human gene segment acquired by recombination

artículo científico publicado en 2012

Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus

artículo científico publicado en 2008

African strains of hepatitis E virus that are distinct from Asian strains ⬇️

artículo científico publicado el 1 de octubre de 1997

Age-specific prevalence of antibodies to hepatitis A and E viruses in Pune, India, 1982 and 1992

artículo científico publicado en 1995

Amplification of the full-length hepatitis A virus genome by long reverse transcription-PCR and transcription of infectious RNA directly from the amplicon.

artículo científico publicado en 1996

An ELISA for putative neutralizing antibodies to hepatitis E virus detects antibodies to genotypes 1, 2, 3, and 4.

artículo científico publicado en 2004

An essential RNA element resides in a central region of hepatitis E virus ORF2.

artículo científico publicado en 2013

Animal models of hepatitis A and E.

artículo científico publicado en 2001

Apolipoprotein C1 Association with Hepatitis C Virus

artículo científico publicado en 2008

Attenuated hepatitis A virus: genetic determinants of adaptation to growth in MRC-5 cells.

artículo científico publicado en 1994

Biological and molecular comparisons of human (HM-175) and simian (AGM-27) hepatitis A viruses

artículo científico publicado en 1991

Capped RNA transcripts of full-length cDNA clones of swine hepatitis E virus are replication competent when transfected into Huh7 cells and infectious when intrahepatically inoculated into pigs

artículo científico publicado en 2005

Characterization of a prototype strain of hepatitis E virus ⬇️

artículo científico publicado el 15 de enero de 1992

Characterization of a strain of infectious hepatitis E virus isolated from sewage in an area where hepatitis E is not endemic.

artículo científico publicado en 1998

Characterization of chimpanzee/human monoclonal antibodies to vaccinia virus A33 glycoprotein and its variola virus homolog in vitro and in a vaccinia virus mouse protection model

artículo científico publicado en 2007

Characterization of hepatitis E-specific cell-mediated immune response using IFN-gamma ELISPOT assay

artículo científico publicado en 2007

Chimpanzee/human mAbs to vaccinia virus B5 protein neutralize vaccinia and smallpox viruses and protect mice against vaccinia virus

artículo científico publicado en 2006

Chlorine inactivation of hepatitis E virus and human adenovirus 2 in water

artículo científico publicado en 2014

Chronic hepatitis E with neurologic manifestations and rapid progression of liver fibrosis in a liver transplant recipient

scientific article published on 20 March 2013

Comparative pathogenesis of infection of pigs with hepatitis E viruses recovered from a pig and a human

artículo científico publicado en 2001

Comparison of tests for antibody to hepatitis E virus

artículo científico publicado en 1998

Complete genome sequence of a rat hepatitis e virus strain isolated in the United States

artículo científico publicado en 2014

Consensus proposals for classification of the family Hepeviridae

artículo científico publicado en 2014

Consensus proposals for classification of the family Hepeviridae

artículo científico publicado en 2015

Contamination of commercially available fetal bovine sera with bovine viral diarrhea virus genomes: implications for the study of hepatitis C virus in cell cultures

artículo científico publicado en 1996

Cross-species infections of cultured cells by hepatitis E virus and discovery of an infectious virus-host recombinant

artículo científico publicado en 2011

DNA immunization of mice and macaques with plasmids encoding hepatitis C virus envelope E2 protein expressed intracellularly and on the cell surface.

artículo científico publicado en 1999

Detection of Antibodies to the Nonstructural 3C Proteinase of Hepatitis A Virus ⬇️

artículo científico publicado el 1 de septiembre de 1997

Detection of antibodies to HAV 3C proteinase in experimentally infected chimpanzees and in naturally infected children

artículo científico publicado en 2001

Detection of immunoglobulin M antibodies to hepatitis E virus by class capture enzyme immunoassay

artículo científico publicado en 2003

Determination and analysis of the complete genomic sequence of avian hepatitis E virus (avian HEV) and attempts to infect rhesus monkeys with avian HEV.

artículo científico publicado en 2004

ELISA for antibody to hepatitis E virus (HEV) based on complete open-reading frame-2 protein expressed in insect cells: identification of HEV infection in primates

artículo científico publicado en 1993

Efficacy of an inactivated hepatitis A vaccine in pre- and postexposure conditions in marmosets

scientific article published on 01 March 1995

Efficient neutralization of anthrax toxin by chimpanzee monoclonal antibodies against protective antigen

artículo científico publicado en 2006

Epidemic hepatitis E in Pakistan: patterns of serologic response and evidence that antibody to hepatitis E virus protects against disease

artículo científico publicado en 1994

Evidence for cross-genotype neutralization of hepatitis C virus pseudo-particles and enhancement of infectivity by apolipoprotein C1

artículo científico publicado en 2005

Evidence for widespread infection of wild rats with hepatitis E virus in the United States.

artículo científico publicado en 1999

Evidence that the genomic RNA of hepatitis E virus is capped

artículo científico publicado en 1999

Experimental Infection of Chimpanzees with Hepatitis G Virus and Genetic Analysis of the Virus ⬇️

artículo científico publicado el 1 de abril de 1998

Experimental hepatitis E in pregnant rhesus monkeys: failure to transmit hepatitis E virus (HEV) to offspring and evidence of naturally acquired antibodies to HEV.

artículo científico publicado en 1995

Experimental infection of pigs with the newly identified swine hepatitis E virus (swine HEV), but not with human strains of HEV.

artículo científico publicado en 1998

Failure to infect rhesus monkeys with hepatitis C virus strains of genotypes 1a, 2a or 3a.

artículo científico publicado en 2001

False-positive serologic test resulting from a probable yeast infection in a chimpanzee

artículo científico publicado en 1996

Four chimpanzee monoclonal antibodies isolated by phage display neutralize hepatitis a virus

artículo científico publicado en 2002

Functional analyses of GB virus B p13 protein: development of a recombinant GB virus B hepatitis virus with a p7 protein.

artículo científico publicado en 2006

Genetic and experimental evidence for cross-species infection by swine hepatitis E virus

artículo científico publicado en 1998

Genotypic characterization of symptomatic hepatitis E virus (HEV) infections in Egypt.

scientific article published on 03 August 2009

Hepatitis A virus translation is rate-limiting for virus replication in MRC-5 cells

artículo científico publicado en 1999

Hepatitis A viruses with deletions in the 2A gene are infectious in cultured cells and marmosets ⬇️

artículo científico publicado el 1 de septiembre de 1995

Hepatitis C Virus (HCV) Proteins Induce NADPH Oxidase 4 Expression in a Transforming Growth Factor -Dependent Manner: a New Contributor to HCV-Induced Oxidative Stress

artículo científico publicado en 2009

Hepatitis C virus envelope protein E2 binds to CD81 of tamarins.

artículo científico publicado en 2000

Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees

artículo científico publicado en 2000

Hepatitis C virus receptors claudin-1 and occludin after liver transplantation and influence on early viral kinetics.

artículo científico publicado en 2011

Hepatitis C virus: an infectious molecular clone of a second major genotype (2a) and lack of viability of intertypic 1a and 2a chimeras

artículo científico publicado en 1999

Hepatitis E

artículo científico publicado en 2007

Hepatitis E antibody seroconversion without disease in highly endemic rural Egyptian communities

artículo científico publicado en 2005

Hepatitis E virus (HEV) capsid antigens derived from viruses of human and swine origin are equally efficient for detecting anti-HEV by enzyme immunoassay

artículo científico publicado en 2002

Hepatitis E virus ORF2 protein over-expressed by baculovirus in hepatoma cells, efficiently encapsidates and transmits the viral RNA to naïve cells ⬇️

artículo científico publicado el 8 de abril de 2011

Hepatitis E virus genotype 1 infection of swine kidney cells in vitro is inhibited at multiple levels

artículo científico publicado en 2013

Hepatitis E virus in rats, Los Angeles, California, USA.

artículo científico publicado en 2011

Hepatitis E virus infection

artículo científico publicado en 2000

Hepatitis E virus.

artículo científico publicado en 2003

Hepatitis E: an emerging awareness of an old disease

artículo científico publicado en 2008

Hidden danger: the raw facts about hepatitis E virus

artículo científico publicado en 2010

High prevalence of TT virus (TTV) in naive chimpanzees and in hepatitis C virus-infected humans: frequent mixed infections and identification of new TTV genotypes in chimpanzees

artículo científico publicado en 2000

High prevalence of TT virus (TTV) infection in patients on maintenance hemodialysis: frequent mixed infections with different genotypes and lack of evidence of associated liver disease

artículo científico publicado en 1999

High prevalence of hepatitis E antibodies in pregnant Egyptian women

artículo científico publicado en 2005

High-level expression of hepatitis C virus (HCV) structural proteins by a chimeric HCV/BVDV genome propagated as a BVDV pseudotype.

artículo científico publicado en 2001

How Escherichia coli can bias the results of molecular cloning: preferential selection of defective genomes of hepatitis C virus during the cloning procedure

artículo científico publicado en 1997

Human monoclonal antibodies that react with the E2 glycoprotein of hepatitis C virus and possess neutralizing activity

artículo científico publicado en 2005

Identification and characterization of a group of discrete initiated oligonucleotides transcribed in vitro from the 3' terminus of the N-gene of vesicular stomatitis virus ⬇️

artículo científico publicado el 1 de junio de 1982

Identification by phage display and characterization of two neutralizing chimpanzee monoclonal antibodies to the hepatitis E virus capsid protein

artículo científico publicado en 2000

Identification of VP1/2A and 2C as virulence genes of hepatitis A virus and demonstration of genetic instability of 2C

artículo científico publicado en 2002

Identification of chimpanzee Fab fragments by repertoire cloning and production of a full-length humanized immunoglobulin G1 antibody that is highly efficient for neutralization of dengue type 4 virus

artículo científico publicado en 2004

Identification of the 5' terminal sequence of the SAR-55 and MEX-14 strains of hepatitis E virus and confirmation that the genome is capped

artículo científico publicado en 2001

Immunogenicity and protective efficacy of a vaccine prepared from 53 kDa truncated hepatitis E virus capsid protein expressed in insect cells

artículo científico publicado en 2001

Importance of amino acid 216 in nonstructural protein 2B for replication of hepatitis A virus in cell culture and in vivo

artículo científico publicado en 2003

In Vivo Study of the HC-TN Strain of Hepatitis C Virus Recovered from a Patient with Fulminant Hepatitis: RNA Transcripts of a Molecular Clone (pHC-TN) Are Infectious in Chimpanzees but Not in Huh7.5 Cells

artículo científico publicado en 2007

In vitro and ex vivo inhibition of hepatitis A virus 3C proteinase by a peptidyl monofluoromethyl ketone.

artículo científico publicado en 1997

In vitro and in vivo mutational analysis of the 3'-terminal regions of hepatitis e virus genomes and replicons

artículo científico publicado en 2005

In vitro assay for neutralizing antibody to hepatitis C virus: Evidence for broadly conserved neutralization epitopes

artículo científico publicado en 2003

In vitro replication of hepatitis E virus (HEV) genomes and of an HEV replicon expressing green fluorescent protein

scientific article published on May 2004

In vitro synthesis of triphosphate-initiated N-gene mRNA oligonucleotides is regulated by the matrix protein of vesicular stomatitis virus ⬇️

artículo científico publicado el 1 de junio de 1982

In vivo analysis of the 3' untranslated region of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA clone

artículo científico publicado en 1999

In vivo transfection by hepatitis A virus synthetic RNA.

artículo científico publicado en 1994

Inactivated hepatitis A vaccine: active and passive immunoprophylaxis in chimpanzees

artículo científico publicado el 1 de enero de 1992

Infection with hepatitis C virus depends on TACSTD2, a regulator of claudin-1 and occludin highly downregulated in hepatocellular carcinoma.

artículo científico publicado en 2018

Infectivity titration of a prototype strain of hepatitis E virus in cynomolgus monkeys

artículo científico publicado en 1994

Intergenotypic chimeric hepatitis E viruses (HEVs) with the genotype 4 human HEV capsid gene in the backbone of genotype 3 swine HEV are infectious in pigs

artículo científico publicado en 2010

Isolation and Characterization of Broadly Neutralizing Human Monoclonal Antibodies to the E1 Glycoprotein of Hepatitis C Virus

artículo científico publicado en 2008

Long PCR amplification of large fragments of viral genomes: a technical overview

artículo científico publicado en 2003

Long PCR and its application to hepatitis viruses: amplification of hepatitis A, hepatitis B, and hepatitis C virus genomes

artículo científico publicado en 1996

Long PCR methodology.

artículo científico publicado en 2003

Molecular basis of virulence and growth of hepatitis A virus in cell culture

artículo científico publicado el 1 de enero de 1992

Molecular evolution of GB virus B hepatitis virus during acute resolving and persistent infections in experimentally infected tamarins

artículo científico publicado en 2009

Monoclonal antibodies that neutralize HEV recognize an antigenic site at the carboxyterminus of an ORF2 protein vaccine ⬇️

artículo científico publicado el 12 de diciembre de 2003

Mutational analysis of the hepatitis C virus E1 glycoprotein in retroviral pseudoparticles and cell-culture-derived H77/JFH1 chimeric infectious virus particles

artículo científico publicado en 2009

Mutations in both the 2B and 2C genes of hepatitis A virus are involved in adaptation to growth in cell culture ⬇️

artículo científico publicado el 1 de febrero de 1992

Mutations responsible for adaptation of hepatitis A virus to efficient growth in cell culture ⬇️

artículo científico publicado el 1 de septiembre de 1991

Mutations within potential glycosylation sites in the capsid protein of hepatitis E virus prevent the formation of infectious virus particles.

artículo científico publicado en 2007

Neutralizing antibodies to hepatitis C virus in perinatally infected children followed up prospectively

artículo científico publicado en 2011

Novel chimpanzee/human monoclonal antibodies that neutralize anthrax lethal factor, and evidence for possible synergy with anti-protective antigen antibody

artículo científico publicado en 2009

ORF3 protein of hepatitis E virus is not required for replication, virion assembly, or infection of hepatoma cells in vitro

artículo científico publicado en 2006

Partial characterization of hepatitis A viruses from three intermediate passage levels of a series resulting in adaptation to growth in cell culture and attenuation of virulence

scientific article published on 01 January 1993

Partial sequence comparison of eight new Chinese strains of hepatitis E virus suggests the genome sequence is relatively stable

artículo científico publicado en 1993

Pathobiology of hepatitis E: lessons learned from primate models

artículo científico publicado en 2013

Pathogenesis of Hepatitis E Virus and Hepatitis C Virus in Chimpanzees: Similarities and Differences ⬇️

artículo científico publicado el 25 de agosto de 2010

Phylogenetic analysis of hepatitis E virus isolates from India (1976-1993).

artículo científico publicado en 1999

Polyprotein processing in echovirus 22: a first assessment

artículo científico publicado en 1995

Positive reactions on Western blots do not necessarily indicate the epitopes on antigens are continuous

artículo científico publicado en 2006

Pre-clinical immunogenicity and efficacy trial of a recombinant hepatitis E vaccine ⬇️

artículo científico publicado el 2 de junio de 2003

Prevalence of antibodies to hepatitis E in two rural Egyptian communities

artículo científico publicado en 2000

Prevalence of antibodies to hepatitis E virus in veterinarians working with swine and in normal blood donors in the United States and other countries

artículo científico publicado en 2002

Prevalence of antibodies to the hepatitis E virus in pigs from countries where hepatitis E is common or is rare in the human population

artículo científico publicado en 1999

Progress toward the development of a genetically engineered attenuated hepatitis A virus vaccine

artículo científico publicado en 1996

Putative neutralization epitopes and broad cross-genotype neutralization of Hepatitis E virus confirmed by a quantitative cell-culture assay

artículo científico publicado en 2006

Recombinant hepatitis E virus genomes infectious for primates: importance of capping and discovery of a cis-reactive element

artículo científico publicado en 2001

Recombinant vaccine against hepatitis E: dose response and protection against heterologous challenge ⬇️

artículo científico publicado el 1 de diciembre de 1997

Recombinant vaccine against hepatitis E: duration of protective immunity in rhesus macaques.

artículo científico publicado en 2002

Recombinant vaccines for hepatitis E.

artículo científico publicado en 2001

Release of genotype 1 hepatitis E virus from cultured hepatoma and polarized intestinal cells depends on open reading frame 3 protein and requires an intact PXXP motif

artículo científico publicado en 2010

Reproduction In Vitro of a Quasispecies from a Hepatitis C Virus-Infected Patient and Determination of Factors That Influence Selection of a Dominant Species ⬇️

artículo científico publicado el 26 de enero de 2011

Ribavirin inhibits in vitro hepatitis E virus replication through depletion of cellular GTP pools and is moderately synergistic with alpha interferon

artículo científico publicado en 2013

Running like water--the omnipresence of hepatitis E.

artículo científico publicado en 2004

Seroepidemiology of water-borne hepatitis in India and evidence for a third enterically-transmitted hepatitis agent

artículo científico publicado en 1994

Serological evidence for a hepatitis e virus-related agent in goats in the United States

artículo científico publicado en 2012

Simian hepatitis A virus (HAV) strain AGM-27: comparison of genome structure and growth in cell culture with other HAV strains

artículo científico publicado el 1 de julio de 1991

Spatial configuration of hepatitis E virus antigenic domain

artículo científico publicado en 2010

Structural Characterization of Recombinant Hepatitis E Virus ORF2 Proteins in Baculovirus-Infected Insect Cells ⬇️

artículo científico publicado el 1 de febrero de 1998

Studies of hepatitis C virus in chimpanzees and their importance for vaccine development.

artículo científico publicado en 2001

Successful passive and active immunization of cynomolgus monkeys against hepatitis E

artículo científico publicado en 1994

The GDPAL region of the pre-S1 envelope protein is important for morphogenesis of woodchuck hepatitis virus

artículo científico publicado en 1998

The entire core protein of HCV JFH1 is required for efficient formation of infectious JFH1 pseudoparticles

artículo científico publicado en 2010

The open reading frame 3 gene of hepatitis E virus contains a cis-reactive element and encodes a protein required for infection of macaques

artículo científico publicado en 2005

The p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequences

artículo científico publicado en 2003

Thermal stability of hepatitis E virus

artículo científico publicado en 2005

Three amino acid mutations (F51L, T59A, and S390L) in the capsid protein of the hepatitis E virus collectively contribute to virus attenuation

artículo científico publicado en 2011

Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee

artículo científico publicado en 1997

Transcripts of a chimeric cDNA clone of hepatitis C virus genotype 1b are infectious in vivo.

artículo científico publicado en 1998

Transfusion-associated hepatitis before the screening of blood for hepatitis risk factors

artículo científico publicado en 2014

Transmission of hepatitis A to patients with hemophilia by factor VIII concentrates treated with organic solvent and detergent to inactivate viruses. The Italian Collaborative Group

artículo científico publicado en 1994

Using improved technology for filter paper-based blood collection to survey wild Sika deer for antibodies to hepatitis E virus

artículo científico publicado en 2007

Utilization of chimeras between human (HM-175) and simian (AGM-27) strains of hepatitis A virus to study the molecular basis of virulence

artículo científico publicado en 1998

Vaccination of chimpanzees with plasmid DNA encoding the hepatitis C virus (HCV) envelope E2 protein modified the infection after challenge with homologous monoclonal HCV.

artículo científico publicado en 2000

Vaccine-induced cross-genotype reactive neutralizing antibodies against hepatitis C virus

artículo científico publicado en 2011

Variation in course of hepatitis E in experimentally infected cynomolgus monkeys

scientific article published on 01 June 1993

Virology of the hepatitis A epidemic in Italy

artículo científico publicado en 1994

cDNA clone of hepatitis A virus encoding a virulent virus: induction of viral hepatitis by direct nucleic acid transfection of marmosets ⬇️

artículo científico publicado el 1 de noviembre de 1992

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