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1-(4-Amino-phenyl)-pyrrolidin-3-yl-amine and 6-(3-amino-pyrrolidin-1-yl)-pyridin-3-yl-amine derivatives as melanin-concentrating hormone receptor-1 antagonists

artículo científico publicado en 2005

A point mutation in the human melanin concentrating hormone receptor 1 reveals an important domain for cellular trafficking

artículo científico publicado en 2005

A thienopyridazinone-based melanin-concentrating hormone receptor 1 antagonist with potent in vivo anorectic properties

artículo científico publicado en 2006

Bis(aminopyrrolidine)-derived ureas (APUs) as potent MCH1 receptor antagonists

artículo científico publicado en 2005

Cutting Edge: Diabetes-Associated Quantitative Trait Locus, Idd4, Is Responsible for the IL-12p40 Overexpression Defect in Nonobese Diabetic (NOD) Mice ⬇️

artículo científico publicado el 1 de octubre de 2003

Differential kinetics of hypocretins in the cerebrospinal fluid after intracerebroventricular administration in rats

artículo científico publicado en 2003

Identification of differentially expressed genes induced by transient ischemic stroke

artículo científico publicado en 2002

Ligand affinity for amino-terminal and juxtamembrane domains of the corticotropin releasing factor type I receptor: regulation by G-protein and nonpeptide antagonists

scientific journal article

Manipulation of small-molecule inhibitory kinetics modulates MCH-R1 function

scientific article published on 20 September 2006

Pharmacological characterization of CXC chemokine receptor 3 ligands and a small molecule antagonist.

artículo científico publicado en 2005

Substituted chromones and quinolones as potent melanin-concentrating hormone receptor 1 antagonists

artículo científico publicado en 2006

Synthesis and structure-activity relationships of biarylcarboxamide bis-aminopyrrolidine urea derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1).

artículo científico publicado en 2005

Synthesis and structure-activity relationships of retro bis-aminopyrrolidine urea (rAPU) derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1). Part 1

artículo científico publicado en 2006

Synthesis and structure-activity relationships of retro bis-aminopyrrolidine urea (rAPU) derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1). Part 2.

artículo científico publicado en 2006

Synthesis and structure-activity relationships of spirohydantoin-derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1)

scientific article published on 04 February 2007

Thienopyrimidinone bis-aminopyrrolidine ureas as potent melanin-concentrating hormone receptor-1 (MCH-R1) antagonists

artículo científico publicado en 2007

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