Lista de obras -

3-Fluoropiperidines and N-methyl-3-fluoropiperidinium salts: the persistence of axial fluorine

artículo científico publicado en 2005

A target site for template-based design of measles virus entry inhibitors.

scholarly article

Adding a Lysine Mimic in the Design of Potent Inhibitors of Histone Lysine Methyltransferases

artículo científico publicado en 2010

An orally available, small-molecule polymerase inhibitor shows efficacy against a lethal morbillivirus infection in a large animal model.

artículo científico publicado en 2014

Antiviral atropisomers: conformational energy surfaces by NMR for host-directed myxovirus blockers

artículo científico publicado en 2014

Asymmetric synthesis of host-directed inhibitors of myxoviruses.

artículo científico publicado en 2013

Autophagy and apoptosis in hepatocellular carcinoma induced by EF25-(GSH)2: a novel curcumin analog

artículo científico publicado en 2014

Cancer and virus leads by HTS, chemical design and SEA data mining

artículo científico publicado en 2009

Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism

artículo científico publicado en 2009

Design of a small-molecule entry inhibitor with activity against primary measles virus strains

artículo científico publicado en 2005

Dicubyl disulfide

artículo científico publicado en 2002

Discovering Small‐Molecule Estrogen Receptor α/Coactivator Binding Inhibitors: High‐Throughput Screening, Ligand Development, and Models for Enhanced Potency ⬇️

artículo científico publicado el 4 de abril de 2011

Discovery of aminoquinolines as a new class of potent inhibitors of heat shock protein 90 (Hsp90): Synthesis, biology, and molecular modeling ⬇️

artículo científico publicado en 2008

Dual Myxovirus Screen Identifies a Small-Molecule Agonist of the Host Antiviral Response ⬇️

artículo científico publicado el 7 de agosto de 2013

EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism

artículo científico publicado en 2005

Ebselen and Congeners Inhibit NADPH Oxidase 2-Dependent Superoxide Generation by Interrupting the Binding of Regulatory Subunits ⬇️

artículo científico publicado el 22 de junio de 2012

Facile synthesis of hierarchical nanocrystalline ZSM-5 zeolite under mild conditions and its catalytic performance

artículo científico publicado en 2011

Genetic association between the Pfk13 gene mutation and artemisinin resistance phenotype in Plasmodium falciparum isolates from Yunnan Province, China

article

High-throughput assays for superoxide and hydrogen peroxide: design of a screening workflow to identify inhibitors of NADPH oxidases.

artículo científico publicado en 2014

High-throughput screening-based identification of paramyxovirus inhibitors

artículo científico publicado en 2008

Host-Directed Inhibitors of Myxoviruses: Synthesis and in Vitro Biochemical Evaluation ⬇️

artículo científico publicado el 23 de agosto de 2011

Inhibition of IkappaB kinase-nuclear factor-kappaB signaling pathway by 3,5-bis(2-flurobenzylidene)piperidin-4-one (EF24), a novel monoketone analog of curcumin

artículo científico publicado en 2008

Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): anti-inflammatory and anti-cancer properties.

artículo científico publicado en 2011

Monocarbonyl analogs of curcumin inhibit growth of antibiotic sensitive and resistant strains of Mycobacterium tuberculosis.

artículo científico publicado en 2015

Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors

artículo científico publicado en 2009

Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor.

artículo científico publicado en 2010

Non-nucleoside Inhibitors of the Measles Virus RNA-Dependent RNA Polymerase: Synthesis, Structure–Activity Relationships, and Pharmacokinetics ⬇️

artículo científico publicado el 20 de abril de 2012

Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex activity: Synthesis and in vitro evaluation

artículo científico publicado en 2007

Nonnucleoside inhibitor of measles virus RNA-dependent RNA polymerase complex activity

artículo científico publicado en 2007

Nonpeptide inhibitors of measles virus entry

artículo científico publicado en 2006

Novel curcumin analogue UBS109 potently stimulates osteoblastogenesis and suppresses osteoclastogenesis: involvement in Smad activation and NF-κB inhibition.

artículo científico publicado en 2012

Potent Host-Directed Small-Molecule Inhibitors of Myxovirus RNA-Dependent RNA-Polymerases ⬇️

artículo científico publicado el 16 de mayo de 2011

Potent non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex

artículo científico publicado en 2008

Rolling Circle Amplification-Based Biosensors

Sphingoid bases and de novo ceramide synthesis: enzymes involved, pharmacology and mechanisms of action

artículo científico publicado en 2003

Synthesis and Metabolic Studies of Host Directed Inhibitors for Anti Viral Therapy

artículo científico publicado en 2013

Synthesis and SAR study of N-(4-hydroxy-3-(2-hydroxynaphthalene-1-yl)phenyl)-arylsulfonamides: heat shock protein 90 (Hsp90) inhibitors with submicromolar activity in an in vitro assay

artículo científico publicado en 2008

Synthesis of EF24-tripeptide chloromethyl ketone: a novel curcumin-related anticancer drug delivery system

artículo científico publicado en 2006

Synthetic curcumin analog EF31 inhibits the growth of head and neck squamous cell carcinoma xenografts

artículo científico publicado en 2012

Synthetic curcumin analog UBS109 inhibits the growth of head and neck squamous cell carcinoma xenografts.

artículo científico publicado en 2014

Target analysis of the experimental measles therapeutic AS-136A

artículo científico publicado en 2009

Targeted delivery of paclitaxel to tumor cells: synthesis and in vitro evaluation

artículo científico publicado en 2010

Targeting tissue factor-expressing tumor angiogenesis and tumors with EF24 conjugated to factor VIIa

scientific article published on 01 April 2008

Thioxo-dihydroquinazolin-one Compounds as Novel Inhibitors of Myeloperoxidase

artículo científico publicado en 2015

Tumor angiogenesis therapy using targeted delivery of Paclitaxel to the vasculature of breast cancer metastases.

artículo científico publicado en 2014

Two domains that control prefusion stability and transport competence of the measles virus fusion protein

artículo científico publicado en 2006

Visualizing cancer and response to therapy in vivo using Cy5.5-labeled factor VIIa and anti-tissue factor antibody

artículo científico publicado en 2014

Lista de obras de

3-Fluoropiperidines and N-methyl-3-fluoropiperidinium salts: the persistence of axial fluorine

A target site for template-based design of measles virus entry inhibitors.

Adding a Lysine Mimic in the Design of Potent Inhibitors of Histone Lysine Methyltransferases

An orally available, small-molecule polymerase inhibitor shows efficacy against a lethal morbillivirus infection in a large animal model.

Antiviral atropisomers: conformational energy surfaces by NMR for host-directed myxovirus blockers

Asymmetric synthesis of host-directed inhibitors of myxoviruses.

Autophagy and apoptosis in hepatocellular carcinoma induced by EF25-(GSH)2: a novel curcumin analog

Cancer and virus leads by HTS, chemical design and SEA data mining

Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism

Design of a small-molecule entry inhibitor with activity against primary measles virus strains

Dicubyl disulfide

Discovering Small‐Molecule Estrogen Receptor α/Coactivator Binding Inhibitors: High‐Throughput Screening, Ligand Development, and Models for Enhanced Potency ⬇️

Discovery of aminoquinolines as a new class of potent inhibitors of heat shock protein 90 (Hsp90): Synthesis, biology, and molecular modeling ⬇️

Dual Myxovirus Screen Identifies a Small-Molecule Agonist of the Host Antiviral Response ⬇️

EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism

Ebselen and Congeners Inhibit NADPH Oxidase 2-Dependent Superoxide Generation by Interrupting the Binding of Regulatory Subunits ⬇️

Facile synthesis of hierarchical nanocrystalline ZSM-5 zeolite under mild conditions and its catalytic performance

Genetic association between the Pfk13 gene mutation and artemisinin resistance phenotype in Plasmodium falciparum isolates from Yunnan Province, China

High-throughput assays for superoxide and hydrogen peroxide: design of a screening workflow to identify inhibitors of NADPH oxidases.

High-throughput screening-based identification of paramyxovirus inhibitors

Host-Directed Inhibitors of Myxoviruses: Synthesis and in Vitro Biochemical Evaluation ⬇️

Inhibition of IkappaB kinase-nuclear factor-kappaB signaling pathway by 3,5-bis(2-flurobenzylidene)piperidin-4-one (EF24), a novel monoketone analog of curcumin

Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): anti-inflammatory and anti-cancer properties.

Monocarbonyl analogs of curcumin inhibit growth of antibiotic sensitive and resistant strains of Mycobacterium tuberculosis.

Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors

Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor.

Non-nucleoside Inhibitors of the Measles Virus RNA-Dependent RNA Polymerase: Synthesis, Structure–Activity Relationships, and Pharmacokinetics ⬇️

Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex activity: Synthesis and in vitro evaluation

Nonnucleoside inhibitor of measles virus RNA-dependent RNA polymerase complex activity

Nonpeptide inhibitors of measles virus entry

Novel curcumin analogue UBS109 potently stimulates osteoblastogenesis and suppresses osteoclastogenesis: involvement in Smad activation and NF-κB inhibition.

Potent Host-Directed Small-Molecule Inhibitors of Myxovirus RNA-Dependent RNA-Polymerases ⬇️

Potent non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex

Rolling Circle Amplification-Based Biosensors

Sphingoid bases and de novo ceramide synthesis: enzymes involved, pharmacology and mechanisms of action

Synthesis and Metabolic Studies of Host Directed Inhibitors for Anti Viral Therapy

Synthesis and SAR study of N-(4-hydroxy-3-(2-hydroxynaphthalene-1-yl)phenyl)-arylsulfonamides: heat shock protein 90 (Hsp90) inhibitors with submicromolar activity in an in vitro assay

Synthesis of EF24-tripeptide chloromethyl ketone: a novel curcumin-related anticancer drug delivery system

Synthetic curcumin analog EF31 inhibits the growth of head and neck squamous cell carcinoma xenografts

Synthetic curcumin analog UBS109 inhibits the growth of head and neck squamous cell carcinoma xenografts.

Target analysis of the experimental measles therapeutic AS-136A

Targeted delivery of paclitaxel to tumor cells: synthesis and in vitro evaluation

Targeting tissue factor-expressing tumor angiogenesis and tumors with EF24 conjugated to factor VIIa

Thioxo-dihydroquinazolin-one Compounds as Novel Inhibitors of Myeloperoxidase

Tumor angiogenesis therapy using targeted delivery of Paclitaxel to the vasculature of breast cancer metastases.

Two domains that control prefusion stability and transport competence of the measles virus fusion protein

Visualizing cancer and response to therapy in vivo using Cy5.5-labeled factor VIIa and anti-tissue factor antibody