Lista de obras -

10% liquid human immunoglobulin (KIOVIG(®)) for immunomodulation in autoimmune disorders

artículo científico publicado en 2016

A caution on the use of murine hemophilia models for comparative immunogenicity studies of FVIII products with different protein compositions

scientific article published on 01 June 2003

A close look at human IgG sialylation and subclass distribution after lectin fractionation

artículo científico publicado en 2009

A comparison of nano-electrospray gas-phase electrophoretic mobility macromolecular analysis and matrix-assisted laser desorption/ionization linear time-of-flight mass spectrometry for the characterization of the recombinant coagulation glycoprotein

artículo científico publicado en 2010

A fully recombinant partial prothrombin complex effectively bypasses fVIII in vitro and in vivo.

artículo científico publicado en 2002

A new mouse model mimicking thrombotic thrombocytopenic purpura: correction of symptoms by recombinant human ADAMTS13.

artículo científico publicado en 2012

ADAMTS13 autoantibody detection by quantitative immunoblotting

artículo científico publicado en 2003

Activated protein C: more effective than nonactivated protein C?

scientific article published on 01 May 2003

Activation and inactivation of human factor X by proteases derived from Ficus carica

artículo científico publicado en 2002

Anti-amyloidogenic activity of IgGs contained in normal plasma

artículo científico publicado en 2010

Beneficial effect of albumin therapy attributable to alpha1-acid glycoprotein?

artículo científico publicado en 2003

Biochemical, molecular characterization, and glycoproteomic analyses of alpha(1)-proteinase inhibitor products used for replacement therapy.

artículo científico publicado en 2006

CD4+ T-cell epitopes associated with antibody responses after intravenously and subcutaneously applied human FVIII in humanized hemophilic E17 HLA-DRB1*1501 mice

artículo científico publicado en 2012

Clinical Immunogenicity of rHuPH20, a Hyaluronidase Enabling Subcutaneous Drug Administration.

artículo científico publicado en 2015

Cloning, expression, and functional characterization of the von Willebrand factor-cleaving protease (ADAMTS13).

artículo científico publicado en 2002

Comparative study on collagen-binding enzyme-linked immunosorbent assay and ristocetin cofactor activity assays for detection of functional activity of von Willebrand factor

artículo científico publicado en 2002

Comparison of plasma-derived and recombinant von Willebrand factor by atomic force microscopy.

artículo científico publicado en 2010

Comprehensive glyco-proteomic analysis of human alpha1-antitrypsin and its charge isoforms

artículo científico publicado en 2006

Convenient high-resolution isoelectric focusing (IEF) method for the separation of alpha1-proteinase inhibitor (A1PI) isoforms in A1PI concentrates

artículo científico publicado en 2007

Development of a transgenic mouse model with immune tolerance for human coagulation factor VIIa

artículo científico publicado en 2013

Development, Validation, and Application of a Novel Ligand-Binding Assay to Selectively Measure PEGylated Recombinant Human Coagulation Factor VIII (BAX 855).

artículo científico publicado en 2015

Distinct characteristics of antibody responses against factor VIII in healthy individuals and in different cohorts of hemophilia A patients.

artículo científico publicado en 2012

Effects of alpha1-acid glycoprotein in combination with catecholamines on hemorrhagic hypovolemic shock in rats

artículo científico publicado en 2004

Efficacy and physiological effects of human butyrylcholinesterase as a post-exposure therapy against percutaneous poisoning by VX in the guinea-pig

artículo científico publicado en 2010

Erratum to: Clinical Immunogenicity of rHuPH20, a Hyaluronidase Enabling Subcutaneous Drug Administration

artículo científico publicado en 2015

Ethanol dependence of alpha 1-antitrypsin C-terminal Lys truncation mediated by basic carboxypeptidases

artículo científico publicado en 2007

Evaluation of the haemostatic potential of factor VIII‐heparin cofactor II hybrid proteins in a mouse model ⬇️

artículo científico publicado el 1 de noviembre de 2003

GEMMA and MALDI-TOF MS of reactive PEGs for pharmaceutical applications

artículo científico publicado en 2010

Glycoproteomic characterization of butyrylcholinesterase from human plasma

artículo científico publicado en 2008

High-dose factor VIII inhibits factor VIII-specific memory B cells in hemophilia A with factor VIII inhibitors

artículo científico publicado en 2005

Human anti-Aβ IgGs target conformational epitopes on synthetic dimer assemblies and the AD brain-derived peptide

artículo científico publicado en 2012

Human anti-macrophage migration inhibitory factor antibodies inhibit growth of human prostate cancer cells in vitro and in vivo

artículo científico publicado en 2013

Human plasma contains cross-reactive Abeta conformer-specific IgG antibodies

scientific article published on 01 November 2008

Immunochemical detection of prion protein on dipsticks prepared with crystalline bacterial cell-surface layers

artículo científico publicado en 2003

In vivo and in vitro processing of recombinant pro-von Willebrand factor

artículo científico publicado en 2002

Induction of immune tolerance by oral IVIG

artículo científico publicado en 2006

Integration of adult patients with phenylketonuria into professional life: long-term follow-up of 27 patients in a single centre in Switzerland

artículo científico publicado en 2014

Karl landsteiner and his major contributions to haematology ⬇️

artículo científico publicado el 1 de mayo de 2003

Long-term persistence of anti-factor VIII antibody-secreting cells in hemophilic mice after treatment with human factor VIII

artículo científico publicado en 2002

Maintenance and break of immune tolerance against human factor VIII in a new transgenic hemophilic mouse model

artículo científico publicado en 2011

Measurement of anti-beta amyloid antibodies in human blood.

artículo científico publicado en 2010

Mechanisms of action of immune tolerance induction against factor VIII in patients with congenital haemophilia A and factor VIII inhibitors

artículo científico publicado en 2007

Mutation of the surface-exposed amino acid Trp to Ala in the FVIII C2 domain results in defective secretion of the otherwise functional protein

artículo científico publicado en 2004

Only activated protein C treatment and not protein C has demonstrated an improvement in survival in severe sepsis

scientific article published on 01 February 2004

Preclinical safety and efficacy of a new recombinant FIX drug product for treatment of hemophilia B.

artículo científico publicado en 2013

Preclinical testing of human recombinant von Willebrand factor: ADAMTS13 cleavage capacity in animals as criterion for species suitability

artículo científico publicado en 2010

Preface: Immunological tango in Barcelona 2011.

artículo científico publicado en 2012

Preventing restimulation of memory B cells in hemophilia A: a potential new strategy for the treatment of antibody-dependent immune disorders

artículo científico publicado en 2004

Proteomic analysis of UVC irradiation-induced damage of plasma proteins: Serum amyloid P component as a major target of photolysis

artículo científico publicado en 2006

Recombinant factor VIII and factor VIII-von Willebrand factor complex do not present danger signals for human dendritic cells

artículo científico publicado en 2006

Recombinant von Willebrand factor-insight into structure and function through infusion studies in animals with severe von Willebrand disease

scientific article published on 01 April 2002

Removal of small nonenveloped viruses by antibody-enhanced nanofiltration during the manufacture of plasma derivatives

artículo científico publicado en 2006

Selective functional activity measurement of a PEGylated protein with a modification-dependent activity assay

artículo científico publicado en 2016

Single cell analysis of factor VIII-specific T cells in hemophilic mice after treatment with human factor VIII

artículo científico publicado en 2002

Stimulation and inhibition of FVIII-specific memory B-cell responses by CpG-B (ODN 1826), a ligand for Toll-like receptor 9 ⬇️

artículo científico publicado el 6 de enero de 2011

Structure and function of a recombinant von Willebrand factor drug candidate

artículo científico publicado en 2010

T cell–independent restimulation of FVIII-specific murine memory B cells is facilitated by dendritic cells together with toll-like receptor 7 agonist ⬇️

artículo científico publicado el 25 de julio de 2011

TT virus does not contaminate first-generation recombinant factor VIII concentrate

artículo científico publicado en 2002

The 1st International Standard for von Willebrand Factor concentrate: more to come?

scientific article published on 01 September 2002

The science and arts of antibodies.

artículo científico publicado en 2014

Therapeutic activities of intravenous immunoglobulins in multiple sclerosis involve modulation of chemokine expression

artículo científico publicado en 2009

Tolerance to factor VIII in a transgenic mouse expressing human factor VIII cDNA carrying an Arg(593) to Cys substitution

artículo científico publicado en 2006

Update on the mechanism of action and future of activated prothrombin complex concentrates.

artículo científico publicado en 2004

Lista de obras de

10% liquid human immunoglobulin (KIOVIG(®)) for immunomodulation in autoimmune disorders

A caution on the use of murine hemophilia models for comparative immunogenicity studies of FVIII products with different protein compositions

A close look at human IgG sialylation and subclass distribution after lectin fractionation

A comparison of nano-electrospray gas-phase electrophoretic mobility macromolecular analysis and matrix-assisted laser desorption/ionization linear time-of-flight mass spectrometry for the characterization of the recombinant coagulation glycoprotein

A fully recombinant partial prothrombin complex effectively bypasses fVIII in vitro and in vivo.

A new mouse model mimicking thrombotic thrombocytopenic purpura: correction of symptoms by recombinant human ADAMTS13.

ADAMTS13 autoantibody detection by quantitative immunoblotting

Activated protein C: more effective than nonactivated protein C?

Activation and inactivation of human factor X by proteases derived from Ficus carica

Anti-amyloidogenic activity of IgGs contained in normal plasma

Beneficial effect of albumin therapy attributable to alpha1-acid glycoprotein?

Biochemical, molecular characterization, and glycoproteomic analyses of alpha(1)-proteinase inhibitor products used for replacement therapy.

CD4+ T-cell epitopes associated with antibody responses after intravenously and subcutaneously applied human FVIII in humanized hemophilic E17 HLA-DRB1*1501 mice

Clinical Immunogenicity of rHuPH20, a Hyaluronidase Enabling Subcutaneous Drug Administration.

Cloning, expression, and functional characterization of the von Willebrand factor-cleaving protease (ADAMTS13).

Comparative study on collagen-binding enzyme-linked immunosorbent assay and ristocetin cofactor activity assays for detection of functional activity of von Willebrand factor

Comparison of plasma-derived and recombinant von Willebrand factor by atomic force microscopy.

Comprehensive glyco-proteomic analysis of human alpha1-antitrypsin and its charge isoforms

Convenient high-resolution isoelectric focusing (IEF) method for the separation of alpha1-proteinase inhibitor (A1PI) isoforms in A1PI concentrates

Development of a transgenic mouse model with immune tolerance for human coagulation factor VIIa

Development, Validation, and Application of a Novel Ligand-Binding Assay to Selectively Measure PEGylated Recombinant Human Coagulation Factor VIII (BAX 855).

Distinct characteristics of antibody responses against factor VIII in healthy individuals and in different cohorts of hemophilia A patients.

Effects of alpha1-acid glycoprotein in combination with catecholamines on hemorrhagic hypovolemic shock in rats

Efficacy and physiological effects of human butyrylcholinesterase as a post-exposure therapy against percutaneous poisoning by VX in the guinea-pig

Erratum to: Clinical Immunogenicity of rHuPH20, a Hyaluronidase Enabling Subcutaneous Drug Administration

Ethanol dependence of alpha 1-antitrypsin C-terminal Lys truncation mediated by basic carboxypeptidases

Evaluation of the haemostatic potential of factor VIII‐heparin cofactor II hybrid proteins in a mouse model ⬇️

GEMMA and MALDI-TOF MS of reactive PEGs for pharmaceutical applications

Glycoproteomic characterization of butyrylcholinesterase from human plasma

High-dose factor VIII inhibits factor VIII-specific memory B cells in hemophilia A with factor VIII inhibitors

Human anti-Aβ IgGs target conformational epitopes on synthetic dimer assemblies and the AD brain-derived peptide

Human anti-macrophage migration inhibitory factor antibodies inhibit growth of human prostate cancer cells in vitro and in vivo

Human plasma contains cross-reactive Abeta conformer-specific IgG antibodies

Immunochemical detection of prion protein on dipsticks prepared with crystalline bacterial cell-surface layers

In vivo and in vitro processing of recombinant pro-von Willebrand factor

Induction of immune tolerance by oral IVIG

Integration of adult patients with phenylketonuria into professional life: long-term follow-up of 27 patients in a single centre in Switzerland

Karl landsteiner and his major contributions to haematology ⬇️

Long-term persistence of anti-factor VIII antibody-secreting cells in hemophilic mice after treatment with human factor VIII

Maintenance and break of immune tolerance against human factor VIII in a new transgenic hemophilic mouse model

Measurement of anti-beta amyloid antibodies in human blood.

Mechanisms of action of immune tolerance induction against factor VIII in patients with congenital haemophilia A and factor VIII inhibitors

Mutation of the surface-exposed amino acid Trp to Ala in the FVIII C2 domain results in defective secretion of the otherwise functional protein

Only activated protein C treatment and not protein C has demonstrated an improvement in survival in severe sepsis

Preclinical safety and efficacy of a new recombinant FIX drug product for treatment of hemophilia B.

Preclinical testing of human recombinant von Willebrand factor: ADAMTS13 cleavage capacity in animals as criterion for species suitability

Preface: Immunological tango in Barcelona 2011.

Preventing restimulation of memory B cells in hemophilia A: a potential new strategy for the treatment of antibody-dependent immune disorders

Proteomic analysis of UVC irradiation-induced damage of plasma proteins: Serum amyloid P component as a major target of photolysis

Recombinant factor VIII and factor VIII-von Willebrand factor complex do not present danger signals for human dendritic cells

Recombinant von Willebrand factor-insight into structure and function through infusion studies in animals with severe von Willebrand disease

Removal of small nonenveloped viruses by antibody-enhanced nanofiltration during the manufacture of plasma derivatives

Selective functional activity measurement of a PEGylated protein with a modification-dependent activity assay

Single cell analysis of factor VIII-specific T cells in hemophilic mice after treatment with human factor VIII

Stimulation and inhibition of FVIII-specific memory B-cell responses by CpG-B (ODN 1826), a ligand for Toll-like receptor 9 ⬇️

Structure and function of a recombinant von Willebrand factor drug candidate

T cell–independent restimulation of FVIII-specific murine memory B cells is facilitated by dendritic cells together with toll-like receptor 7 agonist ⬇️

TT virus does not contaminate first-generation recombinant factor VIII concentrate

The 1st International Standard for von Willebrand Factor concentrate: more to come?

The science and arts of antibodies.

Therapeutic activities of intravenous immunoglobulins in multiple sclerosis involve modulation of chemokine expression

Tolerance to factor VIII in a transgenic mouse expressing human factor VIII cDNA carrying an Arg(593) to Cys substitution

Update on the mechanism of action and future of activated prothrombin complex concentrates.