Lista de obras -

2,4-Diamino-6-methylpyrimidines for the potential treatment of Chagas' disease

artículo científico publicado en 2018

2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization.

artículo científico publicado en 2018

A novel multiple-stage antimalarial agent that inhibits protein synthesis

artículo científico publicado en 2015

Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani

artículo científico publicado en 2017

Chemical synthesis, characterisation and in vitro and in vivo metabolism of the synthetic opioid MT-45 and its newly identified fluorinated analogue 2F-MT-45 with metabolite confirmation in urine samples from known drug users

artículo científico publicado en 2018

Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis

artículo científico publicado en 2016

Development of a Fluorescence-based Trypanosoma cruzi CYP51 Inhibition Assay for Effective Compound Triaging in Drug Discovery Programmes for Chagas Disease

artículo científico publicado en 2015

Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13.

artículo científico publicado en 2017

Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi

artículo científico publicado en 2017

Discovery and Optimization of a Compound Series Active against Trypanosoma cruzi, the Causative Agent of Chagas Disease

artículo científico publicado en 2020

Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1)

Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy

artículo científico publicado en 2016

Discovery of super soft-drug modulators of sphingosine-1-phosphate receptor 1

scholarly article by Mark Bell published in October 2018

Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor.

artículo científico publicado en 2013

Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides

artículo científico publicado en 2016

Identification and optimisation of a series of 8-hydroxy naphthyridines with potent in vitro antileishmanial activity: Initial SAR and assessment of in vivo activity

artículo científico publicado en 2020

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

artículo científico publicado en 2018

Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB

artículo científico publicado en 2018

Identification of Trypanocidal Activity for Known Clinical Compounds Using a New Trypanosoma cruzi Hit-Discovery Screening Cascade.

artículo científico publicado en 2016

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

artículo científico publicado en 2019

Metabolomics and lipidomics reveal perturbation of sphingolipid metabolism by a novel anti-trypanosomal 3-(oxazolo[4,5-b]pyridine-2-yl)anilide

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

scientific article published on 08 April 2019

Re-evaluating pretomanid analogues for Chagas disease: Hit-to-lead studies reveal both in vitro and in vivo trypanocidal efficacy

artículo científico publicado en 2020

Structure-activity relationship studies of pyrrolone antimalarial agents

artículo científico publicado en 2013

Substituted Aminoacetamides as Novel Leads for Malaria Treatment

artículo científico publicado en 2019

Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials

scientific article published on 17 June 2016

Lista de obras de

2,4-Diamino-6-methylpyrimidines for the potential treatment of Chagas' disease

2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization.

A novel multiple-stage antimalarial agent that inhibits protein synthesis

Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani

Chemical synthesis, characterisation and in vitro and in vivo metabolism of the synthetic opioid MT-45 and its newly identified fluorinated analogue 2F-MT-45 with metabolite confirmation in urine samples from known drug users

Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis

Development of a Fluorescence-based Trypanosoma cruzi CYP51 Inhibition Assay for Effective Compound Triaging in Drug Discovery Programmes for Chagas Disease

Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13.

Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi

Discovery and Optimization of a Compound Series Active against Trypanosoma cruzi, the Causative Agent of Chagas Disease

Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1)

Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy

Discovery of super soft-drug modulators of sphingosine-1-phosphate receptor 1

Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor.

Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides

Identification and optimisation of a series of 8-hydroxy naphthyridines with potent in vitro antileishmanial activity: Initial SAR and assessment of in vivo activity

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB

Identification of Trypanocidal Activity for Known Clinical Compounds Using a New Trypanosoma cruzi Hit-Discovery Screening Cascade.

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Metabolomics and lipidomics reveal perturbation of sphingolipid metabolism by a novel anti-trypanosomal 3-(oxazolo[4,5-b]pyridine-2-yl)anilide

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

Re-evaluating pretomanid analogues for Chagas disease: Hit-to-lead studies reveal both in vitro and in vivo trypanocidal efficacy

Structure-activity relationship studies of pyrrolone antimalarial agents

Substituted Aminoacetamides as Novel Leads for Malaria Treatment

Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials