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2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization.

artículo científico publicado en 2018

Application of a novel regulatable Cre recombinase system to define the role of liver and gut metabolism in drug oral bioavailability.

artículo científico publicado en 2015

Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani

artículo científico publicado en 2017

Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis

artículo científico publicado en 2016

Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi

artículo científico publicado en 2017

Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1)

Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy

artículo científico publicado en 2016

Essential but not vulnerable: indazole sulfonamides targeting inosine monophosphate dehydrogenase as potential leads against Mycobacterium tuberculosis

artículo científico publicado en 2016

Identification and optimisation of a series of 8-hydroxy naphthyridines with potent in vitro antileishmanial activity: Initial SAR and assessment of in vivo activity

artículo científico publicado en 2020

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

artículo científico publicado en 2018

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

artículo científico publicado en 2019

Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage

scientific article published on 17 October 2016

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

scientific article published on 08 April 2019

Substituted Aminoacetamides as Novel Leads for Malaria Treatment

artículo científico publicado en 2019

The R enantiomer of the antitubercular drug PA-824 as a potential oral treatment for visceral Leishmaniasis

artículo científico publicado en 2013

The anti-tubercular drug delamanid as a potential oral treatment for visceral leishmaniasis

artículo científico publicado en 2016

Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials

scientific article published on 17 June 2016