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1alpha,25-dihydroxycholecalciferol and cyclosporine suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice

artículo científico publicado en 1999

2-Deoxyglucose sensitizes melanoma cells to TRAIL-induced apoptosis which is reduced by mannose ⬇️

artículo científico publicado el 17 de septiembre de 2010

3-Bromopyruvate induces necrotic cell death in sensitive melanoma cell lines

artículo científico publicado en 2010

4-Tertiary butyl phenol exposure sensitizes human melanocytes to dendritic cell-mediated killing: relevance to vitiligo

artículo científico publicado en 2005

4A11, a monoclonal antibody recognizing a novel antigen expressed on aberrant vascular endothelium. Upregulation in an in vivo model of contact dermatitis.

artículo científico publicado en 1994

56th annual Montagna Symposium on the Biology of Skin: Epidermal T-cell interactions--clinicopathological and basic mechanisms

artículo científico publicado en 2008

A 'hairy' privilege

artículo científico publicado en 2005

A bullous variant of Kaposi's sarcoma in an elderly female

scientific article published on 01 November 1986

A child with erythematous and hyperkeratotic patches. Erythrokeratodermia variabilis

artículo científico publicado en 1988

A fluorometric approach to the quantitation of cell number with application to a cell adhesion assay

scientific article published on 01 May 1988

A fresh morphological and functional look at dermal dendritic cells

artículo científico publicado en 1995

A morphometric and histologic study of the scalp in psoriasis. Paradoxical sebaceous gland atrophy and decreased hair shaft diameters without alopecia

artículo científico publicado en 1989

A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer

artículo científico publicado en 2010

A phase I trial of tumor lysate-pulsed dendritic cells in the treatment of advanced cancer.

artículo científico publicado en 2002

A role for tumor necrosis factor-alpha-mediated endothelial apoptosis in the development of experimental idiopathic pneumonia syndrome

scientific article published on 01 August 2004

Aberrant Intercellular Adhesion Molecule-1 (ICAM-1) Expression by Hair-Follicle Epithelial Cells and Endothelial Leukocyte Adhesion Molecule-1 (ELAM-1) by Vascular Cells Are Important Adhesion-Molecule Alterations in Alopecia Areata ⬇️

artículo científico publicado el 1 de mayo de 1991

Aberrant production of interleukin-8 and thrombospondin-1 by psoriatic keratinocytes mediates angiogenesis.

artículo científico publicado en 1994

Abnormal NF-kappaB signaling pathway with enhanced susceptibility to apoptosis in immortalized keratinocytes

artículo científico publicado en 2001

Abnormal cutaneous topobiology: the molecular basis for dermatopathologic mononuclear cell patterns in inflammatory skin disease

artículo científico

Accessory cell function of keratinocytes for superantigens. Dependence on lymphocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction

artículo científico publicado en 1993

Activated keratinocytes present bacterial-derived superantigens to T lymphocytes: relevance to psoriasis.

artículo científico publicado en 1993

Activation of dendritic antigen-presenting cells expressing common heat shock protein receptor CD91 during induction of psoriasis.

artículo científico publicado en 2005

Active Notch1 confers a transformed phenotype to primary human melanocytes

artículo científico publicado en 2009

Additive and synergistic antiproliferative effects of cyclosporin A and gamma interferon on cultured human keratinocytes.

artículo científico publicado en 1988

Adoptive immunotherapy of cancer with activated lymph node cells primed in vivo with autologous tumor cells transduced with the GM-CSF gene

artículo científico publicado en 1996

Affinity directed reactions of 3-trimethylaminomethyl catechol with the acetylcholine receptor from Torpedo californica

artículo científico publicado en 1982

Affinity-dependent cross-linking to neurotoxin sites of the acetylcholine receptor mediated by catechol oxidation.

artículo científico publicado en 1985

Alefacept in corticosteroid refractory graft versus host disease: early results indicate promising activity

scientific article published on 01 January 2007

All-trans retinoic acid stimulates growth and extracellular matrix production in growth-inhibited cultured human skin fibroblasts

artículo científico publicado en 1990

All-trans retinoic acid stimulates growth of adult human keratinocytes cultured in growth factor-deficient medium, inhibits production of thrombospondin and fibronectin, and reduces adhesion

artículo científico publicado en 1989

Allergic contact dermatitis: novel immunohistologic features

artículo científico publicado en 1986

Anal cancer incidence: genital warts, anal fissure or fistula, hemorrhoids, and smoking

artículo científico publicado en 1989

Animal models of psoriasis

artículo científico publicado en 1999

Animal models of psoriasis

artículo científico publicado en 1997

Anti-beta-4 integrin antibody prominently stains nerves in psoriatic skin

artículo científico publicado en 1991

Antiproliferative effects of recombinant alpha- and gamma-interferons on cultured human keratinocytes

artículo científico publicado en 1984

Apoptosis in keratinocytes is not dependent on induction of differentiation

scientific article published on 01 January 1997

Apoptosis in proliferating, senescent, and immortalized keratinocytes

artículo científico publicado en 1999

Assessment and Clinical Relevance of Serum IL-19 Levels in Psoriasis and Atopic Dermatitis Using a Sensitive and Specific Novel Immunoassay

article

Autoimmune aspects of depigmentation in vitiligo

artículo científico publicado en 2004

Avoiding premature apoptosis of normal epidermal cells

scientific article published on 01 April 2001

Baricitinib in adult patients with moderate-to-severe atopic dermatitis: a phase 2 parallel, double-blinded, randomized placebo-controlled multiple-dose study

artículo científico publicado en 2018

Benign idiopathic versus mycosis fungoides-associated follicular mucinosis

artículo científico publicado en 1985

Beta interferon produced by keratinocytes in human cutaneous infection with herpes simplex virus

artículo científico publicado en 1987

Binding of 125I-gamma interferon to cultured human keratinocytes

artículo científico publicado en 1987

C1q does not complement the removal of apoptotic keratinocytes in vivo

artículo científico publicado en 2001

CD-34 Is Expressed by a Distinctive Cell Population in Peripheral Nerve, Nerve Sheath Tumors, and Related Lesions ⬇️

artículo científico publicado el 1 de octubre de 1993

CD6 dependent interactions of T cells and keratinocytes: functional evidence for a second CD6 ligand on gamma-interferon activated keratinocytes

artículo científico publicado en 1997

CD95-mediated tumor recognition by CD4+ effector cells in a murine mammary model

artículo científico publicado en 2000

Calcium oxalate-phosphate gallstones, a unique chemical type of gallstone

artículo científico publicado en 1982

Canine neuroendocrine carcinoma. A tumor resembling histiocytoma

Capsule Dermatopathology: Dysplastic and Malignant Histiocytic Infiltrates in the Skin ⬇️

artículo científico publicado el 1 de julio de 1983

Caspase activation and disruption of mitochondrial membrane potential during UV radiation-induced apoptosis of human keratinocytes requires activation of protein kinase C.

artículo científico publicado en 2002

Caspase inhibitor blocks human immunodeficiency virus 1-induced T-cell death without enhancement of HIV-1 replication and dimethyl sulfoxide increases HIV-1 replication without influencing T-cell survival

artículo científico publicado en 2000

Cationic lipid is not required for uptake and selective inhibitory activity of ICAM-1 phosphorothioate antisense oligonucleotides in keratinocytes

artículo científico publicado en 1994

Cd1d is expressed on dermal dendritic cells and monocyte-derived dendritic cells

scientific article published on 01 September 2001

Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis ⬇️

artículo científico publicado el 1 de enero de 1991

Cellular, Immunologic and Biochemical Characterization of Topical Retinoic Acid—Treated Human Skin ⬇️

artículo científico publicado el 1 de mayo de 1991

Characterization of NF-kappaB expression in Hodgkin's disease: inhibition of constitutively expressed NF-kappaB results in spontaneous caspase-independent apoptosis in Hodgkin and Reed-Sternberg cells

Characterization of a T cell line bearing natural killer receptors and capable of creating psoriasis in a SCID mouse model system

artículo científico publicado en 2000

Characterization of dermal dendritic cells in psoriasis. Autostimulation of T lymphocytes and induction of Th1 type cytokines

artículo científico publicado en 1994

Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets

artículo científico publicado en 1993

Characterization of factor XIIIa positive dermal dendritic cells in normal and inflamed skin

scientific article published on 01 October 1989

Characterization of insulin-like growth factor-I/somatomedin-C receptors on human keratinocyte monolayers

scientific article published on 01 August 1986

Characterization of intercellular adhesion molecule-1 and HLA-DR expression in normal and inflamed skin: modulation by recombinant gamma interferon and tumor necrosis factor

artículo científico publicado en 1989

Characterization of lymphocyte-dependent angiogenesis using a SCID mouse: human skin model of psoriasis

artículo científico publicado en 2000

Characterization of the Cytokine Storm Reflects Hyperinflammatory Endothelial Dysfunction in COVID-19

scientific article published on 10 September 2020

Characterization of tissue specific expression of Notch-1 in human tissues

artículo científico publicado en 2004

Charting a new course through the chaos of KS (Kaposi's sarcoma)

artículo científico publicado en 1996

Chemokine and inflammatory cytokine changes during chronic wound healing

scientific article published on 01 October 1997

Claudin-1 overexpression in melanoma is regulated by PKC and contributes to melanoma cell motility

artículo científico publicado en 2006

Clinical and histologic features of nevi with emphasis on treatment approaches.

artículo científico publicado en 1987

Clonal persistence and evolution during a decade of recurrent melanoma

artículo científico publicado en 2006

Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials

artículo científico publicado en 2015

Conservation of genetic alterations in recurrent melanoma supports the melanoma stem cell hypothesis.

artículo científico publicado en 2008

Constitutive absence and interferon-γ-induced expression of adhesion molecules in basal cell carcinoma ⬇️

artículo científico publicado el 1 de mayo de 1990

Costimulation of superantigen-activated T lymphocytes by autologous dendritic cells is dependent on B7

Cracking the cytokine code in psoriasis

scientific article published on 01 March 2007

Creation of psoriatic plaques: the ultimate tumor suppressor pathway. A new model for an ancient T-cell-mediated skin disease. Viewpoint

artículo científico publicado en 2001

Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches

artículo científico publicado en 2008

Cross-validation of murine UV signal transduction pathways in human skin

scientific article published on 29 January 2008

Cultured Kaposi's sarcoma cell lines express factor XIIIa, CD14, and VCAM-1, but not factor VIII or ELAM-1

artículo científico publicado en 1993

Cultured Kaposi's sarcoma tumor cells fail to stimulate T cell proliferation

artículo científico publicado en 1996

Cutaneous dendritic cells in the crossfire between innate and adaptive immunity

artículo científico publicado en 2002

Cutaneous expression of Thy-1 in mycosis fungoides ⬇️

artículo científico publicado el 1 de diciembre de 1992

Cutting edge: A critical functional role for IL-23 in psoriasis.

artículo científico publicado en 2010

Cyclosporin wash for oral lichen planus

artículo científico publicado en 1990

Cyclosporine in lamellar ichthyosis

artículo científico publicado en 1989

Decreased growth inhibition by recombinant gamma interferon is associated with increased transforming growth factor-alpha production in keratinocytes cultured from psoriatic lesions

artículo científico publicado en 1989

Deepening our understanding of immune sentinels in the skin

artículo científico publicado en 2007

Defining the caspase-containing apoptotic machinery contributing to cornification in human epidermal equivalents

artículo científico publicado en 2006

Defining the transcriptome of accelerated and replicatively senescent keratinocytes reveals links to differentiation, interferon signaling, and Notch related pathways

artículo científico publicado en 2006

Dermal dendritic cells are important members of the skin immune system

artículo científico publicado en 1995

Dermal dendrocytes and T-cells in canine mycosis fungoides. Support for an animal model of human cutaneous T-cell lymphoma

artículo científico publicado en 1992

Dermal injection of immunocytes induces psoriasis

artículo científico publicado en 1996

Dermatofibroma and dermatofibrosarcoma protuberans: an immunohistochemical study reveals distinctive antigenic profiles

artículo científico publicado en 1996

Dermatofibroma: An Abortive Immunoreactive Process Mediated by Dermal Dendritic Cells? ⬇️

artículo científico publicado el 1 de enero de 1995

Dermatologic complications following heart transplantation

artículo científico publicado en 1986

Detection of human papillomavirus DNA in keratoacanthomas by polymerase chain reaction

scientific article published on 01 February 1997

Detection of interferon-gamma mRNA in psoriatic epidermis by polymerase chain reaction.

artículo científico publicado en 1991

Differential expression of cell survival and cell cycle regulatory proteins in cutaneous squamoproliferative lesions

artículo científico publicado en 1999

Differential expression of factor XIIIa and CD34 in cutaneous mesenchymal tumors ⬇️

artículo científico publicado el 1 de abril de 1993

Differential modulation of keratinocyte intercellular adhesion molecule-I expression by gamma interferon and phorbol ester: evidence for involvement of protein kinase C signal transduction

artículo científico publicado en 1990

Digital epiluminescence microscopy monitoring of high-risk patients

artículo científico publicado en 2004

Direct and indirect control of T-cell activation by keratinocytes

artículo científico publicado en 1995

Direct antiproliferative effect of cyclosporin A on cultured keratinocytes and fibroblasts

artículo científico publicado en 1990

Direct cytopathic effects of cyclosporine A on rapidly proliferating cultured keratinocytes and dermal fibroblasts

artículo científico publicado en 1988

Discordant expression of Bcl-x and Bcl-2 by keratinocytes in vitro and psoriatic keratinocytes in vivo

artículo científico publicado en 1995

Discordant expression of CD28 ligands, BB-1, and B7 on keratinocytes in vitro and psoriatic cells in vivo.

artículo científico publicado en 1993

Disseminated dermal dendrocytomas. A new cutaneous fibrohistiocytic proliferative disorder?

artículo científico publicado en 1990

Distinct biology of Kaposi's sarcoma-associated herpesvirus from primary lesions and body cavity lymphomas

artículo científico publicado en 1998

Distinctive dendritic cell subsets expressing factor XIIIa, CD1a, CD1b and CD1c in mycosis fungoides and psoriasis ⬇️

artículo científico publicado el 1 de junio de 1995

Ecthyma gangrenosum following toxic epidermal necrolysis syndrome in a 3-year-old boy-a survivable series of events

artículo científico publicado en 2008

Effect of neuropeptides present in skin on the proliferation of human peripheral blood mononuclear cells and T cells

scientific article published on 01 January 1988

Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness.

artículo científico publicado en 2006

Enhanced binding of peripheral blood mononuclear leukocytes to gamma-interferon-treated cultured keratinocytes

artículo científico publicado en 1987

Enhanced killing of melanoma cells by simultaneously targeting Mcl-1 and NOXA.

artículo científico publicado en 2006

Eosinophilic infiltration with flame figures. A distinctive tissue reaction seen in Wells' syndrome and other diseases

artículo científico publicado en 1986

Epidermal growth factor and transforming growth factor-alpha decrease gamma interferon receptors and induction of intercellular adhesion molecule (ICAM-1) on cultured keratinocytes

artículo científico publicado el 1 de febrero de 1992

Epidermal mucinosis in mycosis fungoides

scientific article published on 01 July 1986

Epigenetic transdifferentiation of normal melanocytes by a metastatic melanoma microenvironment

artículo científico publicado en 2005

Estimation of size of clonal unit for keratinocytes in normal human skin

artículo científico publicado en 2002

Etiology and pathogenesis of Kaposi's sarcoma

artículo científico publicado en 2002

Expansion of vitiligo lesions is associated with reduced epidermal CDw60 expression and increased expression of HLA-DR in perilesional skin ⬇️

artículo científico publicado el 1 de octubre de 2003

Expression of costimulatory molecules CD80 and/or CD86 by a Kaposi's sarcoma tumor cell line induces differential T-cell activation and proliferation

artículo científico publicado en 1999

Expression of gp100 and CDK2 in melanoma cells is not co-regulated by a shared promoter region

artículo científico publicado en 2004

Expression of the myelomonocytic antigens L1 and CD36 in human epidermis ⬇️

artículo científico publicado el 1 de octubre de 1990

Factor XIIIa-expressing dermal dendrocytes in AIDS-associated cutaneous Kaposi's sarcomas

scientific article published on 01 March 1989

Fatal cutaneous squamous cell carcinoma in a forty-three-year-old male

artículo científico publicado en 1986

Fixed drug eruption. Expression of epidermal keratinocyte intercellular adhesion molecule-1 (ICAM-1).

artículo científico publicado en 1989

Focal adhesion kinase promotes the aggressive melanoma phenotype.

artículo científico publicado en 2005

Follicular spongiosis with intercellular deposition of mucin: observations and speculations

From classical mouse models of psoriasis to a spontaneous xenograft model featuring use of AGR mice

artículo científico publicado en 2005

Further characterization of the keratinocyte somatomedin-C/insulin-like growth factor I (SM-C/IGF-I) receptor and the biological responsiveness of cultured keratinocytes to SM-C/IGF-I

scientific article published on 01 January 1988

Gamma interferon induces different keratinocyte cellular patterns of expression of HLA-DR and DQ and intercellular adhesion molecule-I (ICAM-I) antigens

artículo científico publicado en 1989

Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells

artículo científico publicado en 2005

Gene gun application in the generation of effector T cells for adoptive immunotherapy

artículo científico publicado en 2000

Gene rearrangement studies in lymphoproliferative disorders of skin

artículo científico publicado en 1988

Generalized blistering eruption aggravated by heat. Pemphigus foliaceus

scientific article published on 01 March 1987

Genomic characterization of explant tumorgraft models derived from fresh patient tumor tissue

artículo científico publicado en 2012

Geographically distinct HHV-8 DNA sequences in Saudi Arabian Iatrogenic Kaposi's sarcoma lesions

artículo científico publicado en 1998

Graft-versus-host disease of the skin: life and death on the epidermal edge.

artículo científico publicado en 2004

Growth factor and proto-oncogene expression in psoriasis

artículo científico publicado en 1990

HUT 78 T cells bind to noncytokine-stimulated keratinocytes using a non-CD18-dependent adhesion pathway

artículo científico publicado en 1992

Hepatocyte growth factor in the neighborhood reverses resistance to BRAF inhibitor in melanoma.

artículo científico publicado en 2012

High-level variability in the ORF-K1 membrane protein gene at the left end of the Kaposi's sarcoma-associated herpesvirus genome defines four major virus subtypes and multiple variants or clades in different human populations

artículo científico publicado en 1999

Histamine and cis-urocanic acid augment tumor necrosis factor-alpha mediated induction of keratinocyte intercellular adhesion molecule-1 expression

scientific article published on 01 August 1993

Human dermal dendritic cells process and present soluble protein antigens

artículo científico publicado en 1998

Human herpesvirus 8 reactivation and human immunodeficiency virus type 1 gp120.

artículo científico publicado en 2002

Human immunodeficiency virus (HIV) transcripts identified in HIV-related psoriasis and Kaposi's sarcoma lesions ⬇️

artículo científico publicado el 1 de julio de 1991

Human keratinocyte-lymphocyte reactions in vitro

artículo científico publicado en 1986

Human keratinocytes express functional alpha-MSH (MC1-R) receptors

artículo científico publicado en 2001

Human sunlight-induced basal-cell-carcinoma-associated dendritic cells are deficient in T cell co-stimulatory molecules and are impaired as antigen-presenting cells

artículo científico publicado en 1997

IL-10 production in cutaneous basal and squamous cell carcinomas. A mechanism for evading the local T cell immune response ⬇️

artículo científico publicado el 15 de agosto de 1995

IL-7 in the cell-mediated immune response to a human pathogen

artículo científico publicado en 1995

Id-1 delays senescence but does not immortalize keratinocytes

artículo científico publicado en 2000

Identification of a novel proinflammatory human skin-homing Vγ9Vδ2 T cell subset with a potential role in psoriasis

artículo científico publicado en 2011

Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA-liposome complexes

artículo científico publicado en 1996

Immunobiology of acute cytotoxic drug reactions

scientific article published on January 2008

Immunodiagnosis in cutaneous T cell lymphoma: how does gene expression of the variable region of the T cell receptor fit into the diagnostic and pathophysiological picture of T cell neoplasia

artículo científico publicado en 1992

Immunogenetic therapy of human melanoma utilizing autologous tumor cells transduced to secrete granulocyte-macrophage colony-stimulating factor

artículo científico publicado en 2000

Immunohistochemical detection of papillomavirus antigens in Kaposi's sarcoma

artículo científico publicado en 1992

Immunohistologic patterns of congenital nevocellular nevi

artículo científico publicado en 1986

Immunologic reactions triggered during irritant contact dermatitis

scientific article published on 01 June 1998

Immunological functions of non-professional antigen-presenting cells: new insights from studies of T-cell interactions with keratinocytes

artículo científico publicado en 1994

Immunology of the human nail apparatus: the nail matrix is a site of relative immune privilege

artículo científico publicado en 2005

Immunomodulatory and antiproliferative effect of recombinant alpha, beta, and gamma interferons on cultured human malignant squamous cell lines, SCL-1 and SW-1271

scientific article published on 01 June 1985

Immunopathogenesis of psoriasis

artículo científico publicado en 2007

Immunophenotyping of Skin Cells during Healing of Suction Blister Injury ⬇️

artículo científico publicado el 1 de enero de 1991

In situ polymerase chain reaction-based localization studies support role of human herpesvirus-8 as the cause of two AIDS-related neoplasms: Kaposi's sarcoma and body cavity lymphoma

artículo científico publicado en 1997

In vivo effects of interferon-gamma and anti-interferon-gamma antibody on the experimentally induced lichenoid tissue reaction

scientific article published on 01 August 1988

Increased submucosal factor XIIIa-positive dendrocytes in oral lichen planus

artículo científico publicado en 1994

Induction of HHV-8 lytic cycle replication by inflammatory cytokines produced by HIV-1-infected T cells

artículo científico publicado en 2000

Induction of ICAM-1 expression by epidermal keratinocytes via a paracrine pathway possibly involving dermal dendritic cells

artículo científico publicado el 1 de enero de 1992

Induction of human immunodeficiency virus 1 replication by human herpesvirus 8.

artículo científico publicado en 2001

Induction of new proteins by gamma interferon in cultured human keratinocytes.

artículo científico publicado en 1987

Induction of the synthesis of triton-soluble proteins in human keratinocytes by gamma interferon

artículo científico publicado en 1985

Inflammation and cancer: is the link as simple as we think?

artículo científico publicado en 2005

Inhibition of 125I-epidermal growth factor binding to cultured keratinocytes by antiproliferative molecules gamma interferon, cyclosporin A, and transforming growth factor-beta

artículo científico publicado en 1989

Inhibition of PAX3 by TGF-beta modulates melanocyte viability

scientific article published on 01 November 2008

Inhibitory effect of gamma interferon on cultured human keratinocyte thrombospondin production, distribution, and biologic activities

scientific article published on 01 September 1988

Injection of human herpesvirus-8 in human skin engrafted on SCID mice induces Kaposi's sarcoma-like lesions

artículo científico publicado en 2001

Injection of pre-psoriatic skin with CD4+ T cells induces psoriasis

artículo científico publicado en 1999

Innate immune-related receptors in normal and psoriatic skin

artículo científico publicado en 2003

Interferon-gamma reduces melanosomal antigen expression and recognition of melanoma cells by cytotoxic T cells

artículo científico publicado en 2002

Interferons and psoriasis--1987 perspective

scientific article published on 01 January 1987

Interleukin 12: a potential link between nerve cells and the immune response in inflammatory disorders

artículo científico publicado en 1995

Interleukin-2 stimulates resting human T lymphocytes' response to allogeneic, gamma interferon-treated keratinocytes

artículo científico publicado en 1987

Intraepidermal but not dermal T lymphocytes are positive for a cell-cycle-associated antigen (Ki-67) in mycosis fungoides.

artículo científico publicado en 1990

Intraepidermal psoriatic cytokine network involves gamma interferon, transforming growth factor-alpha, and their cell surface receptors: dysregulation rather than deficiency

artículo científico publicado en 1992

Intralesional cyclosporine in the treatment of psoriasis. A clinical, immunologic, and pharmacokinetic study

scientific article published on 01 January 1990

Is psoriasis a T-cell disease?

artículo científico publicado en 2000

Ixekizumab for psoriasis--Authors' reply

artículo científico publicado en 2016

Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma

artículo científico publicado en 2002

Kaposi's sarcoma tumor cells preferentially express Bcl-xL.

artículo científico publicado en 1996

Kaposiform Hemangioendothelioma of Infancy and Childhood

Kaposiform hemangioendothelioma of infancy and childhood. An aggressive neoplasm associated with Kasabach-Merritt syndrome and lymphangiomatosis

artículo científico publicado en 1993

Keratinocyte CDw60 expression is modulated by both a Th-1 type cytokine IFN-gamma and Th-2 cytokines IL-4 and IL-13: relevance to psoriasis

artículo científico publicado en 2001

Keratinocyte activation following T-lymphocyte binding

artículo científico publicado el 1 de enero de 1992

Keratinocyte class II histocompatibility antigen expression

artículo científico publicado en 1985

Keratinocyte derived soluble factors which influence lymphocyte proliferation

artículo científico publicado en 1988

Keratinocyte intercellular adhesion molecule-1 (ICAM-1) expression precedes dermal T lymphocytic infiltration in allergic contact dermatitis (Rhus dermatitis).

artículo científico publicado en 1989

Keratinocyte interleukin-10 expression is upregulated in tape-stripped skin, poison ivy dermatitis, and Sezary syndrome, but not in psoriatic plaques

artículo científico publicado en 1994

Keratinocyte-derived T cell costimulation induces preferential production of IL-2 and IL-4 but not IFN-gamma

artículo científico publicado en 1994

Keratinocytes and the danger model

artículo científico publicado en 1996

Keratinocytes as initiators of inflammation.

artículo científico publicado en 1991

Keratinocytes derived from psoriatic plaques are resistant to apoptosis compared with normal skin ⬇️

artículo científico publicado el 1 de noviembre de 1997

Keratinocytes produce a lymphocyte inhibitory factor which is partially reversible by an antibody to transforming growth factor-beta

artículo científico publicado en 1988

Keratinocytes regain momentum as instigators of cutaneous inflammation

scientific article published on 27 January 2006

Keratinocytes: key immunocytes of the integument.

artículo científico publicado en 1993

Killing of sarcoma cells by proapoptotic Bcl-X(S): role of the BH3 domain and regulation by Bcl-X(L). ⬇️

artículo científico publicado en 2001

Knock down of p53 levels in human keratinocytes increases susceptibility to type I and type II interferon-induced apoptosis mediated by a TRAIL dependent pathway

artículo científico publicado en 2005

Knockdown of p53 levels in human keratinocytes accelerates Mcl-1 and Bcl-x(L) reduction thereby enhancing UV-light induced apoptosis

artículo científico publicado en 2005

Lentigo maligna with follicular mucinosis

artículo científico publicado en 1985

Lessons learned from psoriatic plaques concerning mechanisms of tissue repair, remodeling, and inflammation

artículo científico publicado en 2006

Leukocyte-endothelium interactions in cutaneous inflammatory processes

artículo científico publicado el 1 de enero de 1992

Leukotriene B4 enhances adherence of human polymorphonuclear leukocytes to dermal microvascular endothelial cells in vitro

scientific article published on 01 January 1988

Levels of cyclosporin in epidermis of treated psoriasis patients differentially inhibit growth of keratinocytes cultured in serum free versus serum containing media

artículo científico publicado en 1988

Life and death signaling in epidermis: following a planned cell death pathway involving a trail that does not lead to skin cancer

artículo científico publicado en 2001

Life and death signaling pathways contributing to skin cancer

artículo científico publicado en 2002

Light-microscopic assessment of 100 patients with patch/plaque-stage mycosis fungoides.

artículo científico publicado en 1988

Liposome-mediated gene transfer into human basal cell carcinoma

artículo científico publicado en 1999

Local administration of dendritic cells inhibits established breast tumor growth: implications for apoptosis-inducing agents

artículo científico publicado en 2001

Localization of clonal T cells to the epidermis in cutaneous T-cell lymphoma

artículo científico publicado en 1994

Loss of Inositol Polyphosphate 5-Phosphatase Is an Early Event in Development of Cutaneous Squamous Cell Carcinoma ⬇️

artículo científico publicado el 28 de septiembre de 2010

Loss of miR-204 expression is a key event in melanoma

artículo científico publicado en 2018

Low-dose UV-radiation sensitizes keratinocytes to TRAIL-induced apoptosis

artículo científico publicado en 2004

Lymphocyte trafficking in psoriasis: a new perspective emphasizing the dermal dendrocyte with active dermal recruitment mediated via endothelial cells followed by intra-epidermal T-cell activation

artículo científico publicado el 1 de noviembre de 1990

Lymphocyte-keratinocyte interactions mediated through interferon. New observations relevant to psoriasis

artículo científico publicado el 1 de noviembre de 1984

Lymphocytic infiltrates of the skin in association with cyclosporine therapy.

artículo científico publicado en 1990

Lymphoepitheliomalike carcinoma of the skin. A case report with immunophenotypic analysis and in situ hybridization for Epstein-Barr viral genome

artículo científico publicado en 1992

Maintenance of hair follicle immune privilege is linked to prevention of NK cell attack

artículo científico publicado en 2007

Malodorous intertriginous pustules and plaques. Pemphigus vegetans, Hallopeau type

artículo científico publicado en 1987

Marked synergism between tumor necrosis factor-alpha and interferon-gamma in regulation of keratinocyte-derived adhesion molecules and chemotactic factors

artículo científico publicado en 1990

Markedly diminished epidermal keratinocyte expression of intercellular adhesion molecule-1 (ICAM-1) in Sézary syndrome

artículo científico publicado en 1989

Mechanism of baricitinib supports artificial intelligence-predicted testing in COVID-19 patients

artículo científico publicado en 2020

Melanoma genotypes and phenotypes get personal

artículo científico publicado en 2013

Melanoma patient derived xenografts acquire distinct Vemurafenib resistance mechanisms.

artículo científico publicado en 2015

Merkel Cell Tumor of the Thigh ⬇️

artículo científico publicado el 1 de abril de 1988

Microcystic adnexal carcinoma treated by microscopically controlled excision

scientific article published on 01 November 1984

Microcystic adnexal carcinoma. Immunohistologic observations suggesting dual (pilar and eccrine) differentiation

artículo científico publicado en 1986

Modulation of fibronectin production in normal human melanocytes and malignant melanoma cells by interferon-gamma and tumor necrosis factor-alpha

artículo científico publicado en 1989

Modulation of keratinocyte biology by gamma interferon: relevance to cutaneous wound healing

artículo científico publicado en 1991

Modulation of keratinocyte motility. Correlation with production of extracellular matrix molecules in response to growth promoting and antiproliferative factors.

artículo científico publicado en 1988

Modulation of keratinocyte-derived interleukin-8 which is chemotactic for neutrophils and T lymphocytes ⬇️

artículo científico publicado el 1 de octubre de 1991

Modulation of leucocyte adhesion molecules, a T-cell chemotaxin (IL-8) and a regulatory cytokine (TNF-alpha) in allergic contact dermatitis (rhus dermatitis)

scientific article published on 01 June 1991

Molecular Insights into Fully Human and Humanized Monoclonal Antibodies: What are the Differences and Should Dermatologists Care?

artículo científico publicado en 2016

Molecular and pathologic characterization of an AIDS-related body cavity-based lymphoma, including ultrastructural demonstration of human herpesvirus-8: a case report

artículo científico publicado en 1998

Molecular pathology of malignant melanoma

artículo científico publicado en 1998

Monocyte chemotaxis and activating factor production by keratinocytes in response to IFN-gamma

artículo científico publicado en 1991

Mycosis fungoides exhibits a Th1-type cell-mediated cytokine profile whereas Sezary syndrome expresses a Th2-type profile

scientific article published on 01 July 1994

Mycosis fungoides in relation to environmental exposures and immune response: a case-control study

artículo científico publicado en 1989

NAP-1/IL-8 immunoreactivity in normal and psoriatic skin

artículo científico publicado en 1991

NOTCH signaling as a novel cancer therapeutic target

artículo científico publicado en 2006

Neurotropic malignant melanoma: a novel treatment approach combining modified microscopically controlled surgery and S100 immunohistochemical staining

artículo científico publicado en 1985

New strategies for psoriasis therapy.

artículo científico

Not all spindled-shaped cells embedded in a collagenous stroma are fibroblasts: recognition of the "collagen-associated dendrophage"

artículo científico publicado en 1990

Notch and NOXA-related pathways in melanoma cells.

artículo científico publicado en 2005

Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents

artículo científico publicado en 2003

Notch signaling regulates mouse and human Th17 differentiation

artículo científico publicado en 2011

Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells.

artículo científico publicado en 2008

Notch-1 regulates cell death independently of differentiation in murine erythroleukemia cells through multiple apoptosis and cell cycle pathways

artículo científico publicado en 2004

Notch-independent regulation of Hes-1 expression by c-Jun N-terminal kinase signaling in human endothelial cells

Notch1 is an effector of Akt and hypoxia in melanoma development

artículo científico publicado en 2008

Occurrence of a basal cell carcinoma and dermatofibroma in a smallpox vaccination scar

artículo científico publicado en 2007

Ontogeny and characterization of factor XIIIa+ cells in developing human skin

scientific article published on 01 January 1996

Oral cyclosporine for the treatment of alopecia areata. A clinical and immunohistochemical analysis

artículo científico publicado en 1990

Oral cyclosporine in the treatment of inflammatory and noninflammatory dermatoses. A clinical and immunopathologic analysis

artículo científico publicado en 1990

Oral submucosal dendrocytes: factor XIIIa+ and CD34+ dendritic cell populations in normal tissue and fibrovascular lesions ⬇️

artículo científico publicado el 1 de octubre de 1992

Overexpression of Akt converts radial growth melanoma to vertical growth melanoma.

artículo científico publicado en 2007

Overexpression of CD1d by keratinocytes in psoriasis and CD1d-dependent IFN-gamma production by NK-T cells

artículo científico publicado en 2000

Overexpression of IL-10 in atopic dermatitis. Contrasting cytokine patterns with delayed-type hypersensitivity reactions.

artículo científico publicado en 1995

PECAM-1 (CD31) is expressed on proliferating endothelial cells, stromal spindle-shaped cells, and dermal dendrocytes in Kaposi's sarcoma

artículo científico publicado en 1993

Pathogenesis and immunointervention strategies for psoriasis. IBC's Inflammatory Skin Disorders. Washington, DC, USA. September 17-18, 1998

scientific article published on 01 December 1998

Pathophysiology of cutaneous inflammation ⬇️

artículo científico publicado el 1 de enero de 1992

Pathways involved in proliferating, senescent and immortalized keratinocyte cell death mediated by two different TRAIL preparations

artículo científico publicado en 2002

Perforating pseudoxanthoma elasticum associated with chronic renal failure and hemodialysis

Perturbation of epidermal barrier function correlates with initiation of cytokine cascade in human skin

scientific article published on 01 April 1994

Pharmacologic inhibition of MEK signaling prevents growth of canine hemangiosarcoma

scientific article published on 26 June 2013

Phase 3 Trials of Ixekizumab in Moderate-to-Severe Plaque Psoriasis

artículo científico publicado en 2016

Phenotype and proliferation characteristics of cultured spindle-shaped cells obtained from normal human skin and lesions of dermatofibroma, Kaposi's sarcoma, and dermatofibrosarcoma protuberans: a comparison with fibroblast and endothelial cells of

artículo científico publicado en 1997

Phorbol ester treatment enhances binding of mononuclear leukocytes to autologous and allogeneic gamma-interferon-treated keratinocytes, which are blocked by anti-LFA-1 monoclonal antibody

artículo científico publicado en 1988

Physical interaction of human papillomavirus virus-like particles with immune cells

artículo científico

Pigmented papules in the axilla. Urticaria pigmentosa (UP) (mastocytosis)

artículo científico publicado el 1 de septiembre de 1988

Plasma somatomedin-C levels in psoriasis

scientific article published on 01 January 1987

Preferential binding of monocytes and Leu 2+ T lymphocytes to interferon-gamma treated cultured skin endothelial cells and keratinocytes

artículo científico publicado en 1988

Primary malignant melanoma of the larynx.

artículo científico publicado en 2001

Production and utilization of extracellular matrix components by human melanocytes

artículo científico publicado en 1989

Proliferating cultured human keratinocytes are more susceptible to apoptosis compared with mouse keratinocytes

scientific article published on 01 December 2004

Propagation of a human herpesvirus from AIDS-associated Kaposi's sarcoma

artículo científico publicado en 1997

Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells

artículo científico publicado en 2005

Protein kinase Cdelta is activated by caspase-dependent proteolysis during ultraviolet radiation-induced apoptosis of human keratinocytes

artículo científico publicado en 1998

Pruritic erythematous linear plaques on the neck and back. "Flagellate" erythema secondary to bleomycin therapy

artículo científico publicado en 1987

Pseudotumor resulting from atypical mycobacterial infection: a "histoid" variety of Mycobacterium avium-intracellulare complex infection

artículo científico publicado en 1985

Psoriasis: The Poster Child for Bench-to-bedside Translational Medicine.

artículo científico publicado en 2015

Psoriatic skin-derived dendritic cell function is inhibited by exogenous IL-10. Differential modulation of B7-1 (CD80) and B7-2 (CD86) expression

artículo científico publicado en 1995

Quantification of cutaneous sensory nerves and their substance P content in psoriasis

artículo científico publicado en 1989

Random DNA fragmentation allows detection of single-copy, single-exon alterations of copy number by oligonucleotide array CGH in clinical FFPE samples

artículo científico publicado en 2009

Reactivity of resident immunocytes in normal and prepsoriatic skin using an ex vivo skin-explant model system

scientific article published on 01 March 2003

Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities

artículo científico publicado en 2004

Recent observations regarding interferon, keratinocytes and lymphocytes in vitro and in vivo

artículo científico publicado en 1988

Recombinant Gamma Interferon Induces HLA-DR Expression on Cultured Human Keratinocytes ⬇️

artículo científico publicado el 1 de agosto de 1984

Recombinant gamma interferon differentially regulates class II antigen expression and biosynthesis on cultured normal human keratinocytes

scientific article published on 01 January 1985

Recombinant gamma interferon increases the binding of peripheral blood mononuclear leukocytes and a Leu-3+ T lymphocyte clone to cultured keratinocytes and to a malignant cutaneous squamous carcinoma cell line that is blocked by antibody against the

artículo científico publicado en 1988

Regulation of apoptosis by p53 in UV-irradiated human epidermis, psoriatic plaques and senescent keratinocytes

artículo científico publicado en 2002

Replicative response, immunophenotype, and functional activity of monocyte-derived versus CD34(+)-derived dendritic cells following exposure to various expansion and maturational stimuli

scientific article published on 01 February 2001

Resistance to UV‐induced apoptosis in human keratinocytes during accelerated senescence is associated with functional inactivation of p53 ⬇️

artículo científico publicado el 1 de enero de 2004

Response of murine and normal human skin to injection of allogeneic blood-derived psoriatic immunocytes: detection of T cells expressing receptors typically present on natural killer cells, including CD94, CD158, and CD161

artículo científico publicado en 1999

Responsiveness of human T lymphocytes to bacterial superantigens presented by cultured rheumatoid arthritis synoviocytes

artículo científico publicado en 1996

Retinoic acid stimulation of human dermal fibroblast proliferation is dependent on suboptimal extracellular Ca2+ concentration

artículo científico publicado en 1990

Role for Id-1 in immunobiology of normal keratinocytes and in basal cell carcinoma

artículo científico publicado en 2003

Role of IFI 16, a member of the interferon-inducible p200-protein family, in prostate epithelial cellular senescence

artículo científico publicado en 2003

Role of INK4a/Arf locus-encoded senescent checkpoints activated in normal and psoriatic keratinocytes

artículo científico publicado en 2003

Role of NF-kappaB activity in apoptotic response of keratinocytes mediated by interferon-gamma, tumor necrosis factor-alpha, and tumor-necrosis-factor-related apoptosis-inducing ligand

artículo científico publicado en 2001

Role of NF-kappaB in the apoptotic-resistant phenotype of keratinocytes.

artículo científico publicado en 1999

Role of dendritic cells in benign and malignant lymphocytic infiltrates of the skin

artículo científico publicado en 1994

Role of interferon-gamma in cutaneous trafficking of lymphocytes with emphasis on molecular and cellular adhesion events

artículo científico publicado en 1988

Role of scatter factor and the c-met protooncogene in the pathogenesis of AIDS-associated Kaposi's sarcoma

artículo científico publicado en 1995

Role of scatter factor in the pathogenesis of AIDS-related Kaposi sarcoma.

artículo científico publicado en 1994

Saving the skin from drug-induced detachment

artículo científico publicado en 2008

Scatter factor (hepatocyte growth factor) is a potent angiogenesis factor in vivo

artículo científico publicado en 1993

Scatter factor induces blood vessel formation in vivo ⬇️

artículo científico publicado el 1 de marzo de 1993

Seminoma metastasis to the terminal ileum after a 17-year disease-free interval

scientific article published on 01 November 1983

Senescent human keratinocytes suppress colony formation of HeLa cells

artículo científico publicado en 2005

Sensing and killing bacteria in skin: innate immune defense system: good and bad news

artículo científico publicado en 2001

Severe combined immunodeficiency mouse and human psoriatic skin chimeras. Validation of a new animal model.

artículo científico publicado en 1995

Skin immune sentinels in health and disease ⬇️

artículo científico publicado en 2009

Skin innate immune system in psoriasis: friend or foe?

artículo científico publicado en 1999

Solitary labial papular acantholytic dyskeratoma in an immunocompromised host

artículo científico publicado en 1987

Specifically targeting ERK1 or ERK2 kills melanoma cells

artículo científico publicado en 2012

Sphingosine inhibits phorbol ester-induced inflammation, ornithine decarboxylase activity, and activation of protein kinase C in mouse skin

artículo científico publicado en 1988

Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha

artículo científico publicado en 2004

Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model

artículo científico publicado en 2004

Stress, symmetry, and psoriasis: possible role of neuropeptides.

artículo científico publicado en 1986

Sulfasalazine improves psoriasis. A double-blind analysis.

artículo científico publicado en 1990

Sunlight-induced basal cell carcinoma tumor cells and ultraviolet-B-irradiated psoriatic plaques express Fas ligand (CD95L) ⬇️

artículo científico publicado el 1 de enero de 1998

Superantigens, autoantigens, and pathogenic T cells in psoriasis

scientific article published on 01 April 1998

Suppression of murine allergic contact dermatitis by CTLA4Ig. Tolerance induction of Th2 responses requires additional blockade of CD40-ligand

article

Sweet's syndrome presenting as an unusual periorbital eruption

artículo científico publicado en 1991

Sweet's syndrome with neurologic manifestations in a patient with esophageal adenocarcinoma: case report and review of the literature

artículo científico publicado en 2009

T cell-dependent antitumor immunity mediated by secondary lymphoid tissue chemokine: augmentation of dendritic cell-based immunotherapy.

artículo científico publicado en 2001

T lymphocytes and monocytes bind to keratinocytes in frozen sections of biopsy specimens of normal skin treated with gamma interferon

artículo científico publicado en 1989

T lymphocytes in skin lesions of psoriasis and mycosis fungoides express B7-1: a ligand for CD28

scientific article published on 01 May 1994

Targeting TNFalpha rapidly reduces density of dendritic cells and macrophages in psoriatic plaques with restoration of epidermal keratinocyte differentiation

artículo científico publicado en 2007

Targeting glutamine metabolism sensitizes melanoma cells to TRAIL-induced death

artículo científico publicado en 2010

The Cytokine Network in Lesional and Lesion-Free Psoriatic Skin Is Characterized by a T-Helper Type 1 Cell-Mediated Response

article

The Notch ligand Jagged-1 is able to induce maturation of monocyte-derived human dendritic cells

artículo científico publicado en 2002

The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.

artículo científico publicado en 2007

The cytokine and chemokine network in psoriasis

artículo científico publicado en 2007

The cytokine network in psoriasis

artículo científico publicado en 1991

The helix-loop-helix protein id-1 delays onset of replicative senescence in human endothelial cells

artículo científico publicado en 2002

The human progenitor cell antigen (CD34) is localized on endothelial cells, dermal dendritic cells, and perifollicular cells in formalin-fixed normal skin, and on proliferating endothelial cells and stromal spindle-shaped cells in Kaposi's sarcoma

scientific article published on 01 April 1991

The hypoxic microenvironment of the skin contributes to Akt-mediated melanocyte transformation.

artículo científico publicado en 2005

The immunologic and genetic basis of psoriasis

artículo científico publicado en 1999

The many molecular mysteries of melanoma

artículo científico

The proapoptotic tumor suppressor protein kinase C-delta is lost in human squamous cell carcinomas

artículo científico publicado en 2006

The road to change and transition: resizing, reinvestment and restructuring in Ontario's health system

artículo científico publicado en 1998

The role of adhesion molecules, chemotactic factors, and cytokines in inflammatory and neoplastic skin disease--1990 update

artículo científico

The role of scatter factor and the c-met proto-oncogene in angiogenic responses.

artículo científico publicado en 1995

The search for pathogenic T cells and the genetic basis of psoriasis using a severe combined immunodeficient mouse model

scientific article published on 01 February 2000

The skin cancer paradox of psoriasis: a matter of life and death decisions in the epidermis

scientific article published on 01 July 2004

The spindle-shaped cells in cutaneous Kaposi's sarcoma. Histologic simulators include factor XIIIa dermal dendrocytes

artículo científico publicado en 1989

The tumour necrosis factor-alpha inhibitor adalimumab rapidly reverses the decrease in epidermal Langerhans cell density in psoriatic plaques.

artículo científico publicado en 2005

The validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD™): The development and reliability testing of a novel clinical outcome measurement instrument for the severity of atopic dermatitis

artículo científico publicado en 2020

Thrombospondin binding by keratinocytes: modulation under conditions which alter thrombospondin biosynthesis

artículo científico publicado en 1990

Thrombospondin-induced adhesion of human keratinocytes

artículo científico publicado en 1988

Topical and light-based treatments for basal cell carcinoma

artículo científico publicado en 2003

Topical cyclosporine A inhibits the phorbol ester induced hyperplastic inflammatory response but not protein kinase C activation in mouse epidermis

artículo científico publicado en 1989

Transendothelial function of human metastatic melanoma cells: role of the microenvironment in cell-fate determination

scientific article published on 01 February 2002

Treatment of severe lichen planus with cyclosporine

artículo científico publicado en 1990

Treatment strategies in toxic epidermal necrolysis syndrome: where are we at?

artículo científico publicado en 2008

Tumor stage mycosis fungoides in a patient treated with long-term corticosteroids for asthma and atopic-like dermatitis

artículo científico publicado en 1986

Tumor suppressor maspin is up-regulated during keratinocyte senescence, exerting a paracrine antiangiogenic activity

artículo científico publicado en 2004

Ultrastructural effects of recombinant gamma-interferon on cultured human keratinocytes

artículo científico publicado en 1986

Uncovering histologic criteria with prognostic significance in toxic epidermal necrolysis

artículo científico publicado en 2005

Use of recombinant interferon gamma administered intramuscularly for the treatment of psoriasis

scientific article published on 01 December 1987

What have we learned in dermatology from the biologic therapies?

artículo científico publicado en 2006

What is the 'true' function of skin?

artículo científico publicado en 2002

Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation.

artículo científico publicado en 2008

p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas

artículo científico publicado en 2004

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