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A Chimeric Plasmodium falciparum Merozoite Surface Protein Vaccine Induces High Titers of Parasite Growth Inhibitory Antibodies

artículo científico publicado el 29 de julio de 2013

A potent malaria transmission blocking vaccine based on codon harmonized full length Pfs48/45 expressed in Escherichia coli

artículo científico publicado en 2009

Activation of innate immunity in healthy Macaca mulatta macaques by a single subcutaneous dose of GMP CpG 7909: safety data and interferon-inducible protein-10 kinetics for humans and macaques

artículo científico publicado en 2007

Analysis of factors affecting the variability of a quantitative suspension bead array assay measuring IgG to multiple Plasmodium antigens

artículo científico publicado en 2018

Anti-sporozoite antibodies as alternative markers for malaria transmission intensity estimation

artículo científico publicado en 2014

Antibody profiles to plasmodium merozoite surface protein-1 in Cambodian adults during an active surveillance cohort with nested treatment study

artículo científico publicado en 2016

Antibody responses to the RTS,S/AS01E vaccine and Plasmodium falciparum antigens after a booster dose within the phase 3 trial in Mozambique

scientific article published on 04 June 2020

Antibody-mediated growth inhibition of Plasmodium falciparum: relationship to age and protection from parasitemia in Kenyan children and adults

artículo científico publicado en 2008

Assessment of the Combined Effect of Epstein-Barr Virus and Plasmodium falciparum Infections on Endemic Burkitt Lymphoma Using a Multiplex Serological Approach

artículo científico publicado en 2017

Blood stage malaria vaccine eliciting high antigen-specific antibody concentrations confers no protection to young children in Western Kenya

artículo científico publicado en 2009

C3d binding to the circumsporozoite protein carboxy-terminus deviates immunity against malaria.

artículo científico publicado en 2005

C3d-defined complement receptor-binding peptide p28 conjugated to circumsporozoite protein provides protection against Plasmodium berghei.

artículo científico publicado en 2007

Cellular and humoral immune effector mechanisms required for sterile protection against sporozoite challenge induced with the novel malaria vaccine candidate CelTOS

artículo científico publicado el 29 de junio de 2011

Characterization of a human reference standard for antibody to Plasmodium falciparum merozoite surface protein 1(42).

artículo científico publicado en 2005

Comparison of Plasmodium berghei challenge models for the evaluation of pre-erythrocytic malaria vaccines and their effect on perceived vaccine efficacy

artículo científico publicado en 2010

Complement and Antibody-mediated Enhancement of Red Blood Cell Invasion and Growth of Malaria Parasites

artículo científico publicado en 2016

Computational and experimental validation of B and T-cell epitopes of the in vivo immune response to a novel malarial antigen

artículo científico publicado en 2013

Contrasting Patterns of Serologic and Functional Antibody Dynamics to Plasmodium falciparum Antigens in a Kenyan Birth Cohort

artículo científico publicado en 2015

Correlation Between Malaria-Specific Antibody Profiles and Responses to Artemisinin Combination Therapy for Treatment of Uncomplicated Malaria in Western Kenya

scientific article published on 01 May 2019

Critical evaluation of different methods for measuring the functional activity of antibodies against malaria blood stage antigens.

artículo científico publicado en 2006

Cytokine and antibody responses to Plasmodium falciparum in naïve individuals during a first malaria episode: effect of age and malaria exposure

artículo científico publicado en 2013

DNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunity

artículo científico publicado en 2013

Development and pre-clinical analysis of a Plasmodium falciparum Merozoite Surface Protein-1(42) malaria vaccine

artículo científico publicado en 2003

Development of a chimeric Plasmodium berghei strain expressing the repeat region of the P. vivax circumsporozoite protein for in vivo evaluation of vaccine efficacy

artículo científico publicado en 2013

Differential Patterns of IgG Subclass Responses to Antigens in Relation to Malaria Protection and RTS,S Vaccination

article

Effect of the pre-erythrocytic candidate malaria vaccine RTS,S/AS01E on blood stage immunity in young children

artículo científico publicado en 2011

Effects on immunogenicity by formulations of emulsion-based adjuvants for malaria vaccines

artículo científico publicado en 2012

Enzyme-linked immunosorbent assay for detection of Plasmodium falciparum histidine-rich protein 2 in blood, plasma, and serum

artículo científico publicado en 2008

Erratum: Author Correction: Antibody responses to the RTS,S/AS01E vaccine and Plasmodium falciparum antigens after a booster dose within the phase 3 trial in Mozambique

scientific article published on 20 July 2020

Evaluation of immunoglobulin purification methods and their impact on quality and yield of antigen-specific antibodies

artículo científico publicado en 2008

Evaluation of the Immunogenicity and Vaccine Potential of Recombinant Plasmodium falciparum Merozoite Surface Protein 8

artículo científico publicado el 14 de mayo de 2012

Evaluation of the safety and immunogenicity of Plasmodium falciparum apical membrane antigen 1, merozoite surface protein 1 or RTS,S vaccines with adjuvant system AS02A administered alone or concurrently in rhesus monkeys.

artículo científico publicado en 2009

Expression, immunogenicity, histopathology, and potency of a mosquito-based malaria transmission-blocking recombinant vaccine.

artículo científico publicado en 2012

Heterologous protein expression is enhanced by harmonizing the codon usage frequencies of the target gene with those of the expression host.

artículo científico publicado en 2008

High antibody responses against Plasmodium falciparum in immigrants after extended periods of interrupted exposure to malaria

artículo científico publicado en 2013

Histidine affinity tags affect MSP1(42) structural stability and immunodominance in mice

artículo científico publicado en 2011

Immunization with Pre-Erythrocytic Antigen CelTOS from Plasmodium falciparum Elicits Cross-Species Protection against Heterologous Challenge with Plasmodium berghei

artículo científico publicado el 19 de agosto de 2010

Impact of pre-existing MSP1(42)-allele specific immunity on potency of an erythrocytic Plasmodium falciparum vaccine

artículo científico publicado en 2012

Impact of the RTS,S malaria vaccine candidate on naturally acquired antibody responses to multiple asexual blood stage antigens

artículo científico publicado en 2011

Inhibitory and blocking monoclonal antibody epitopes on merozoite surface protein 1 of the malaria parasite Plasmodium falciparum

artículo científico publicado en 2001

MSP-1p42-specific antibodies affect growth and development of intra-erythrocytic parasites of Plasmodium falciparum

artículo científico publicado en 2009

Marked variation in MSP-119 antibody responses to malaria in western Kenyan highlands

artículo científico publicado en 2012

Miniaturization of a high-throughput pLDH-based Plasmodium falciparum growth inhibition assay for small volume samples from preclinical and clinical vaccine trials.

artículo científico publicado en 2008

Molecular adjuvants for malaria DNA vaccines based on the modulation of host-cell apoptosis

artículo científico publicado en 2009

Molecular vaccines for malaria

artículo científico publicado en 2010

Mosquito Bite-Induced Controlled Human Malaria Infection with Plasmodium vivax or P. falciparum Generates Immune Responses to Homologous and Heterologous Preerythrocytic and Erythrocytic Antigens

scientific article published on 21 February 2019

Multiple comparisons analysis of serological data from an area of low Plasmodium falciparum transmission

artículo científico publicado en 2015

Nanovaccines for malaria using Plasmodium falciparum antigen Pfs25 attached gold nanoparticles

artículo científico publicado en 2015

Optimization of incubation conditions of Plasmodium falciparum antibody multiplex assays to measure IgG, IgG1-4, IgM and IgE using standard and customized reference pools for sero-epidemiological and vaccine studies

artículo científico publicado en 2018

Phase 1 randomized double-blind safety and immunogenicity trial of Plasmodium falciparum malaria merozoite surface protein FMP1 vaccine, adjuvanted with AS02A, in adults in western Kenya

artículo científico publicado en 2005

Phase 1/2a study of the malaria vaccine candidate apical membrane antigen-1 (AMA-1) administered in adjuvant system AS01B or AS02A.

artículo científico publicado en 2009

Phase I safety and immunogenicity trial of FMP1/AS02A, a Plasmodium falciparum MSP-1 asexual blood stage vaccine

artículo científico publicado en 2005

Potent malaria transmission-blocking antibody responses elicited by Plasmodium falciparum Pfs25 expressed in Escherichia coli after successful protein refolding

scientific article published on 13 January 2014

Pre-clinical evaluation of the malaria vaccine candidate P. falciparum MSP1(42) formulated with novel adjuvants or with alum

artículo científico publicado en 2004

Process development and analysis of liver-stage antigen 1, a preerythrocyte-stage protein-based vaccine for Plasmodium falciparum

artículo científico publicado en 2005

Protection induced by Plasmodium falciparum MSP1(42) is strain-specific, antigen and adjuvant dependent, and correlates with antibody responses

artículo científico publicado en 2008

RTS,S/AS01<sub>E</sub> malaria vaccine induces IgA responses against CSP and vaccine-unrelated antigens in African children in the phase 3 trial

artículo científico publicado en 2020

RTS,S/AS01E immunization increases antibody responses to vaccine-unrelated Plasmodium falciparum antigens associated with protection against clinical malaria in African children: A case-control study

artículo científico publicado en 2019

Recent advances in recombinant protein-based malaria vaccines

artículo científico publicado en 2015

Results from tandem Phase 1 studies evaluating the safety, reactogenicity and immunogenicity of the vaccine candidate antigen Plasmodium falciparum FVO merozoite surface protein-1 (MSP1(42)) administered intramuscularly with adjuvant system AS01.

artículo científico publicado en 2013

Safety and allele-specific immunogenicity of a malaria vaccine in Malian adults: results of a phase I randomized trial

artículo científico publicado en 2006

Safety and immunogenicity of an AMA-1 malaria vaccine in Malian adults: results of a phase 1 randomized controlled trial

artículo científico publicado en 2008

Safety and reactogenicity of an MSP-1 malaria vaccine candidate: a randomized phase Ib dose-escalation trial in Kenyan children

artículo científico publicado en 2006

Self-Adjuvanting Bacterial Vectors Expressing Pre-Erythrocytic Antigens Induce Sterile Protection Against Malaria

artículo científico publicado el 4 de julio de 2013

Sero-catalytic and Antibody Acquisition Models to Estimate Differing Malaria Transmission Intensities in Western Kenya

artículo científico publicado en 2017

Seroprevalence of antibodies against plasmodium falciparum sporozoite antigens as predictive disease transmission markers in an area of Ghana with seasonal malaria transmission

artículo científico publicado en 2016

Strain-specific Plasmodium falciparum growth inhibition among Malian children immunized with a blood-stage malaria vaccine

artículo científico publicado en 2017

Suramin and suramin analogues inhibit merozoite surface protein-1 secondary processing and erythrocyte invasion by the malaria parasite Plasmodium falciparum

artículo científico publicado en 2003

Surveillance for malaria elimination in Swaziland: a national cross-sectional study using pooled PCR and serology

artículo científico publicado en 2012

The clinical-grade 42-kilodalton fragment of merozoite surface protein 1 of Plasmodium falciparum strain FVO expressed in Escherichia coli protects Aotus nancymai against challenge with homologous erythrocytic-stage parasites

artículo científico publicado en 2005

Towards an RTS,S-based, multi-stage, multi-antigen vaccine against falciparum malaria: progress at the Walter Reed Army Institute of Research.

artículo científico publicado en 2005