Lista de obras -

3′,5′-cyclic AMP and the release of polysone-bound proteins in vitro ⬇️

artículo científico

A Mouse Model for Human Anal Cancer ⬇️

artículo científico publicado el 6 de octubre de 2010

A North Central Cancer Treatment Group Phase II trial of 9-aminocamptothecin in previously untreated patients with measurable metastatic colorectal carcinoma

artículo científico publicado en 2000

A Phase I study of bizelesin (NSC 615291) in patients with advanced solid tumors.

artículo científico publicado en 2002

A Phase I trial of the farnesyl protein transferase inhibitor R115777 in combination with gemcitabine and cisplatin in patients with advanced cancer

artículo científico publicado en 2003

A Phase II study of high-dose paclitaxel in patients with advanced neuroendocrine tumors

artículo científico publicado en 2001

A Prospective Genome-Wide Study of Prostate Cancer Metastases Reveals Association of Wnt Pathway Activation and Increased Cell Cycle Proliferation with Primary Resistance to Abiraterone Acetate-Prednisone.

artículo científico publicado en 2017

A clonal growth model: time-course simulations of liver foci growth following penta- or hexachlorobenzene treatment in a medium-term bioassay.

artículo científico publicado en 2001

A comparison of polysomal messenger ribonucleoprotein particles from normal and neoplastic rat liver ⬇️

artículo científico publicado el 1 de julio de 1978

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

artículo científico publicado en 1990

A method for the comparative study of replicative DNA synthesis in GGT-positive and GGT-negative hepatocytes in primary culture isolated from carcinogen-treated rats

scientific article published on 01 October 1988

A method to quantitate the relative initiating and promoting potencies of hepatocarcinogenic agents in their dose-response relationships to altered hepatic foci

artículo científico publicado en 1987

A new thiol proteinase from rat liver

artículo científico publicado en 1981

A partial characterization of human fibroblast plasma membranes isolated by the fluorescein mercuric acetate method of Barland and Schroeder

artículo científico publicado el 1 de mayo de 1977

A phase 2 consortium (P2C) trial of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) for advanced adenocarcinoma of the pancreas

artículo científico publicado en 2008

A phase I and pharmacokinetic study of a powder-filled capsule formulation of oral irinotecan (CPT-11) given daily for 5 days every 3 weeks in patients with advanced solid tumors

artículo científico publicado en 2005

A phase I and pharmacologic study of pyrazoloacridine (NSC 366140) and carboplatin in patients with advanced cancer

artículo científico publicado en 2002

A phase I and pharmacologic study of sequences of the proteasome inhibitor, bortezomib (PS-341, Velcade), in combination with paclitaxel and carboplatin in patients with advanced malignancies

artículo científico publicado en 2006

A phase I and pharmacologic trial of two schedules of the proteasome inhibitor, PS-341 (bortezomib, velcade), in patients with advanced cancer

artículo científico publicado en 2005

A phase I study of radiation therapy and twice-weekly gemcitabine and cisplatin in patients with locally advanced pancreatic cancer

artículo científico publicado en 2003

A phase I study of sequential irinotecan and 5-fluorouracil/leucovorin

artículo científico publicado en 2002

A phase I trial of ISIS 2503, an antisense inhibitor of H-ras, in combination with gemcitabine in patients with advanced cancer.

artículo científico publicado en 2003

A phase I trial of the novel farnesyl protein transferase inhibitor, BMS-214662, in combination with paclitaxel and carboplatin in patients with advanced cancer.

artículo científico publicado en 2005

A phase IB study of the pharmacokinetics of gemcitabine and pemetrexed, when administered in rapid sequence to patients with advanced solid tumors

artículo científico publicado en 2005

A phase II safety and efficacy study of the vascular endothelial growth factor receptor tyrosine kinase inhibitor pazopanib in patients with metastatic urothelial cancer

artículo científico publicado en 2013

A phase II study of ABT-510 (thrombospondin-1 analog) for the treatment of metastatic melanoma

artículo científico publicado en 2007

A phase II study of intravenous 6-thioguanine (NSC-752) in advanced colorectal carcinoma

artículo científico publicado el 1 de junio de 1992

A phase II trial of 17-allylamino-17- demethoxygeldanamycin in patients with hormone-refractory metastatic prostate cancer

artículo científico publicado en 2005

A phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with hormone-refractory metastatic prostate cancer

artículo científico publicado en 2008

A potent modifier of liver cancer risk on distal mouse chromosome 1: linkage analysis and characterization of congenic lines.

artículo científico publicado en 2004

A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer.

artículo científico publicado en 2003

A role for HPV16 E5 in cervical carcinogenesis

artículo científico publicado en 2010

A semipurified diet that suppresses phenobarbital promotion of hepatocarcinogenesis in the rat

artículo científico publicado en 1989

A software package to improve image quality and isolation of objects of interest for quantitative stereology studies of rat hepatocarcinogenesis

artículo científico publicado en 2006

ADP-ribosyltransferase activity in cultured hepatocytes. Interactions with DNA repair ⬇️

artículo científico publicado el 25 de mayo de 1982

ALTERED TEMPLATE STABILITY: THE MOLECULAR MASK OF MALIGNANCY?

scientific article published on 01 January 1964

Abnormal cholesterol uptake, storage, and synthesis in the livers of 2-acetylaminofluorene-fed rats

artículo científico publicado el 1 de junio de 1973

Abnormal proteins in Drosophila melanogaster subsequent to 5-bromodeoxyuridine administration

artículo científico publicado en 1974

Accumulation of actin microfilaments in adult rat hepatocytes cultured on collagen gel/nylon mesh

artículo científico publicado en 1980

Acetylated polyamines as substrates for human pregnancy serum diamine oxidase

artículo científico publicado en 1981

Acetylation of nascent polypeptide chains on rat liver polyribosomes in vivo and in vitro ⬇️

artículo científico publicado el 8 de abril de 1975

Acetylation of ribosome-associated proteins in vitro by an acetyltransferase bound to rat liver ribosomes ⬇️

artículo científico publicado el 8 de abril de 1975

Action of actinomycin D on tryptophan uptake in the adrenalectomized rat and its effect on induction of tryptophan pyrrolase and tyrosine transaminase in liver

artículo científico publicado en 1970

Activities of benzphetamine N-demethylase and aryl hydrocarbon hydroxylase in cells isolated from gamma-glutamyl transpeptidase-positive foci and surrounding liver

artículo científico publicado en 1985

Adjuvant external beam radiation therapy with concurrent chemotherapy in the management of gallbladder carcinoma

artículo científico publicado en 2002

Adventures in hepatocarcinogenesis

artículo científico publicado en 2007

Aging and cancer: some general thoughts

artículo científico publicado en 1989

Aging lowers steady-state antioxidant enzyme and stress protein expression in primary hepatocytes

artículo científico publicado en 2001

Alteration of ribosomal precursor RNA in Novikoff hepatoma cells by 5-azacytidine. Studies on methylation of 45S and 32S RNA.

artículo científico publicado en 1974

Alterations in enzymes of amino acid catabolism in livers of rats bearing the Morris 7800 hepatoma ⬇️

artículo científico publicado el 1 de abril de 1978

Alterations in specific gene expression and focal neoplastic growth during spontaneous hepatocarcinogenesis in albumin-SV40 T antigen transgenic rats

artículo científico publicado en 2004

Alterations in the maturation and structure of ribosomal precursor RNA in Novikoff hepatoma cells induced by 5-fluorocytidine

artículo científico publicado en 1984

Altered hepatic foci: their role in murine hepatocarcinogenesis

artículo científico

Amino acid-rich medium (Leibovitz L-15) enhances and prolongs proliferation of primary cultured rat hepatocytes in the absence of serum.

artículo científico publicado en 1991

An approach to the determination of the relative potencies of chemical agents during the stages of initiation and promotion in multistage hepatocarcinogenesis in the rat.

artículo científico publicado en 1987

An approach to the development of a short-term whole-animal bioassay to distinguish initiating agents (incomplete carcinogens), promoting agents, complete carcinogens, and noncarcinogens in rat liver

artículo científico publicado en 1985

An energy-dependent activation of trypttophan pyrrolase

scientific article published on 01 June 1961

An enzymic study on the cellular origin of the DUNNING and the NOVIKOFF hepatomas in the rat ⬇️

artículo científico

An examination of rat liver smooth endoplasmic reticulum membranes for the presence of associated messenger RNA

artículo científico publicado el 1 de diciembre de 1978

An improved stereologic method for three-dimensional estimation of particle size distribution from observations in two dimensions and its application

artículo científico publicado en 2003

An initiation-promotion assay in rat liver as a potential complement to the 2-year carcinogenesis bioassay

artículo científico publicado en 1991

An international, multicenter phase II trial of bortezomib in patients with hepatocellular carcinoma.

artículo científico publicado en 2010

Analbuminemic rats

artículo científico publicado el 1 de julio de 1992

Androgen Receptor Variant AR-V9 Is Coexpressed with AR-V7 in Prostate Cancer Metastases and Predicts Abiraterone Resistance.

artículo científico publicado en 2017

Animal models of neoplastic development

artículo científico publicado el 1 de enero de 2001

Application of quantitative stereology to the evaluation of enzyme-altered foci in rat liver.

artículo científico publicado en 1982

Application of quantitative stereology to the evaluation of phenotypically heterogeneous enzyme-altered foci in the rat liver

artículo científico publicado en 1986

BIOCHEMICAL LESIONS IN MINIMAL DEVIATION HEPATOMAS

artículo científico publicado en 1964

Biallelic expression of the H19 gene during spontaneous hepatocarcinogenesis in the albumin SV40 T antigen transgenic rat

artículo científico publicado en 2003

Biochemical and immunologic studies on the native and deglycosylated forms of gamma-glutamyltranspeptidase of rat kidney

artículo científico publicado en 1986

Biochemical characterisation of stages of hepatocarcinogenesis after a single dose of diethylnitrosamine ⬇️

artículo científico publicado el 2 de febrero de 1978

Biochemical events during initiation of rat hepatocarcinogenesis

scientific article published on 01 July 1994

Biochemical markers associated with the stages of promotion and progression during hepatocarcinogenesis in the rat ⬇️

artículo científico publicado el 1 de junio de 1991

Bioinformatics approaches for cross-species liver cancer analysis based on microarray gene expression profiling

artículo científico publicado en 2005

Biological and Enzymatic Events in Chemical Carcinogenesis ⬇️

artículo científico publicado el 1 de enero de 1979

Biological markers characterizing the development of preneoplastic and neoplastic lesions in rodent liver

artículo científico publicado en 1987

Breast cancer

artículo científico publicado en 1992

Building quantitative stereology data files with scion image, a public domain image processing and analysis software

artículo científico publicado en 1999

Cancer advisory board

artículo científico publicado en 1982

Cancer and the environment: overview.

artículo científico publicado en 1980

Capecitabine and oxaliplatin in the preoperative multimodality treatment of rectal cancer: surgical end points from National Surgical Adjuvant Breast and Bowel Project trial R-04

artículo científico publicado en 2014

Carbohydrate repression of enzyme induction in rat liver

artículo científico publicado en 1963

Carcinogenesis and aging--two related phenomena? A review ⬇️

artículo científico publicado el 1 de mayo de 1977

Carcinoid heart disease. Clinical and echocardiographic spectrum in 74 patients ⬇️

artículo científico publicado el 1 de abril de 1993

Cathepsin T

artículo científico publicado en 1987

Cathepsin T (convertase) generates the multiple forms of tyrosine aminotransferase by limited proteolysis

scientific article published on 01 January 1982

Cell lines with heterogeneous phenotypes result from a single isolation of albumin-sv40 T-antigen transgenic rat hepatocytes

artículo científico publicado en 1997

Cervical Cancers Require the Continuous Expression of the Human Papillomavirus Type 16 E7 Oncoprotein Even in the Presence of the Viral E6 Oncoprotein ⬇️

artículo científico publicado el 13 de junio de 2012

Changes in the DNA methylation profile of the rat H19 gene upstream region during development and transgenic hepatocarcinogenesis and its role in the imprinted transcriptional regulation of the H19 gene

artículo científico publicado en 2004

Characteristics of microsomal enzyme controls in primary cultures of rat hepatocytes ⬇️

artículo científico publicado el 1 de enero de 1979

Characteristics of small cell colonies developing in primary cultures of adult rat hepatocytes

artículo científico publicado el 1 de enero de 1992

Characteristics of the Carbohydrate Moiety and the Intermolecular Associations of the High-Molecular-Weight Forms of α2u-Globulin ⬇️

artículo científico publicado el 1 de junio de 1980

Characterization and sequence of a cDNA clone of gamma-glutamyltranspeptidase

artículo científico publicado en 1986

Characterization of a cytoplasmic histone-coenzyme A acetyltransferase

artículo científico publicado en 1971

Characterization of a proteolipid complex of aminoacyl-tRNA synthetases and transfer RNA from rat liver ⬇️

artículo científico publicado el 24 de mayo de 1979

Characterization of polyribosomes and maturation of ribosomal RNA in hepatoma cells treated with 5-azacytidine

artículo científico publicado en 1974

Characterization of protein kinase activity associated with rat liver polysomal messenger ribonucleoprotein particles ⬇️

artículo científico publicado el 8 de julio de 1980

Characterization of radioactive immunochemically precipitated protein antigens using SDS-polyacrylamide gels ⬇️

artículo científico publicado el 1 de diciembre de 1971

Characterization of rarep53 mutants from carcinogen-treated albumin–simian virus 40 T-antigen transgenic rats ⬇️

artículo científico publicado el 1 de febrero de 1998

Characterization of the Stage of Progression in Hepatocarcinogenesis in the Rat ⬇️

artículo científico publicado el 1 de enero de 1991

Characterization of the major DNA adducts in the liver of rats chronically exposed to tamoxifen for 18 months

scientific article published on 01 April 2000

Characterization of the promotion of altered hepatic foci by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the female rat

artículo científico publicado el 1 de agosto de 1992

Characterization of the rat Class 3 aldehyde dehydrogenase gene promoter

artículo científico publicado en 1996

Chemical quantification of unscheduled DNA synthesis in cultured hepatocytes as an assay for the rapid screening of potential chemical carcinogens

artículo científico publicado en 1982

Chemicals and cancer: initiation and promotion

scientific article published on 01 July 1983

Chemicals, cell proliferation, risk estimation, and multistage carcinogenesis

artículo científico publicado en 1991

Cholangiocellular carcinomas induced in Syrian golden hamsters administered aflatoxin B1 in large doses

artículo científico publicado el 1 de febrero de 1982

Chromatin structure of the c-myc gene in HL-60 cells during alterations of transcriptional activity

artículo científico publicado en 1985

Class 3 aldehyde dehydrogenase. A northern perspective in the land down under.

artículo científico publicado en 1995

Cloning of DNA complementary to ornithine aminotransferase mRNA ⬇️

artículo científico publicado el 10 de mayo de 1982

Co-induction of the hepatic amino acid transport system and tyrosine aminotransferase by theophylline, glucagon and dibutyryl-cyclic AMP in vivo

artículo científico publicado en 1970

Colocalized alterations in connexin32 and cytochrome P450IIB1/2 by phenobarbital and related liver tumor promoters

artículo científico publicado en 1994

Combination epigenetic therapy in metastatic colorectal cancer (mCRC) with subcutaneous 5-azacitidine and entinostat: a phase 2 consortium/stand up 2 cancer study

artículo científico publicado en 2017

Combination of paclitaxel and carboplatin as second-line therapy for patients with metastatic melanoma

artículo científico publicado en 2006

Comparative effects of actinomycin and ionizing radiation on enzyme synthesis in mammalian cells in vivo

artículo científico publicado en 1968

Comparative pharmacokinetic study of continuous venous infusion fluorouracil and oral fluorouracil with eniluracil in patients with advanced solid tumors

artículo científico publicado en 2002

Comparison of continuous versus categorical tumor measurement-based metrics to predict overall survival in cancer treatment trials

artículo científico publicado en 2011

Comparison of experimental and theoretical parameters of the Moolgavkar-Venzon-Knudson incidence function for the stages of initiation and promotion in rat hepatocarcinogenesis

artículo científico publicado en 1995

Comparison of hepatocyte phenotypes at the glutathione transferase and albumin loci in Sprague-Dawley and Nagase analbuminemic rats and F1 progeny after initiation and promotion

artículo científico publicado en 1993

Comparison of the effects of tamoxifen and toremifene on liver and kidney tumor promotion in female rats ⬇️

artículo científico publicado el 1 de noviembre de 1995

Competitive DNA-RNA hybridization of microsomal and nuclear RNA in normal tissues of the rat

artículo científico publicado el 1 de octubre de 1973

Competitive DNA-RNA hybridization of nuclear and microsomal RNA in normal, neoplastic, and neonatal liver tissue

scientific article published on 01 October 1973

Competitive RNA-DNA hybridization of nuclear and microsomal RNA during diethylnitrosamine hepatocarcinogenesis.

artículo científico publicado en 1973

Consequences of altered poly(ADP-ribose) metabolism on hepatocyte functions in vitro

artículo científico publicado el 1 de enero de 1983

Contribution of the Morris Hepatomas to the Biochemistry of Cancer — Establishment of the Phenotypic Heterogeneity of Neoplasms In Vivo ⬇️

artículo científico publicado el 22 de mayo de 1977

Control Mechanisms in the Normal and Neoplastic Cell* ⬇️

artículo científico publicado en 1965

Control of biochemical expression in morphologically related cells in vivo and in vitro

artículo científico publicado en 1967

Correlation of rat liver membrane binding of polysomes in vitro with function of the complexes formed

artículo científico publicado en 1973

CpG PatternFinder: a Windows-based utility program for easy and rapid identification of the CpG methylation status of DNA.

artículo científico publicado en 2007

CpG analyzer, a Windows-based utility program for investigation of DNA methylation

scientific article published on 01 November 2005

Critical parameters in the quantitation of the stages of initiation, promotion, and progression in one model of hepatocarcinogenesis in the rat.

artículo científico publicado en 1989

Crystal Structure of Serine Dehydratase from Rat Liver, ⬇️

artículo científico publicado el 11 de noviembre de 2003

Cyclic adenosine 3',5'-monophosphate during glucose repression in the rat liver

artículo científico publicado en 1971

Cyclic nucleotide binding sites of the smooth endoplasmic reticulum from normal and neoplastic liver in the rat ⬇️

artículo científico publicado el 1 de noviembre de 1975

Cystic fibrosis. A dilemma in the metabolic pathogenesis of genetic disease

artículo científico publicado el 1 de enero de 1976

Cytochrome P-450 induction by phenobarbital and 3-methylcholanthrene in primary cultures of hepatocytes

scientific article published on 01 September 1976

Cytogenetic analysis of three rat liver epithelial cell lines (WBneo, WBHa-ras, and WBrasIIa) and correlation of an early chromosomal alteration with insulin-like growth factor II expression

artículo científico publicado en 1996

DNA Damage and Repair in - Glutamyltranspeptidase-Positive and Negative Hepatocytes in Primary Culture from Carcinogen-Treated Rats

artículo científico publicado el 1 de enero de 1991

DNA damage induced by the antihistaminic drug methapyrilene hydrochloride

scientific article published on 01 March 1982

Decay of cytoplasmic polyadenylated RNA's labeled with [3H]orotate in rat liver and the effect of the re-utilization of labeled precursor on such decay

artículo científico publicado el 28 de junio de 1977

Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer

artículo científico publicado en 2010

Definition of stages during hepatocarcinogenesis in the rat: potential application to the evaluation of initiating and promoting agents in the environment

artículo científico publicado el 1 de septiembre de 1978

Dependence of the induction of cytochrome P-450 by phenobarbital in primary cultures of adult rat hepatocytes on the composition of the culture medium

artículo científico publicado en 1989

Determining the affinity in vitro of hepatic ribosomal subunits for derivatives of the rough endoplasmic reticulum

scientific article published on 01 September 1973

Diamine oxidase activity in fibroblasts from normal and cystic fibrosis patients

artículo científico publicado en 1980

Dietary effects on initiation and promotion of hepatocarcinogenesis in rat.

artículo científico publicado en 1988

Dietary induction of some enzymes of amino acid metaboli during azo dye feeding

artículo científico

Dietary induction of some enzymes of amino acid metabolism during 2-acetylaminofluorene feeding

artículo científico publicado en 1969

Dietary induction of some enzymes of amino acid metabolism following the acute administration of aminoazo dyes

artículo científico publicado en 1970

Dietary induction of some enzymes of carbohydrate metabolism during 2-acetylaminofluorene feeding

artículo científico

Dietary oat lipids-induced novel DNA modifications and suppression of altered hepatic foci formation

scientific article published on 01 January 1999

Differences in the expression of connexin genes in rat hepatomas in vivo and in vitro

artículo científico publicado en 1994

Differential gene expression in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Noncoordinate regulation of a TCDD-induced aldehyde dehydrogenase and cytochrome P-450c in the rat

artículo científico publicado en 1988

Direct association of messenger RNA labeled in the presence of fluoroorotate with membranes of the endoplasmic reticulum in rat liver ⬇️

artículo científico publicado el 1 de julio de 1976

Disruption of estrogen receptor signaling enhances intestinal neoplasia in Apc(Min/+) mice

artículo científico publicado en 2009

Diurnal variation of the serine dehydratase mRNA level in rat liver

artículo científico publicado en 1994

Dominant role of HPV16 E7 in anal carcinogenesis ⬇️

artículo científico publicado el 13 de octubre de 2011

Dr. Elizabeth C. Miller (1920-1987).

artículo científico publicado en 1988

Drug metabolism and effects of carcinogens in cultured hepatic cells ⬇️

artículo científico publicado el 1 de septiembre de 1979

E6-associated protein is required for human papillomavirus type 16 E6 to cause cervical cancer in mice

artículo científico publicado en 2010

ENDOPLASMIC RETICULUM AND HEPATIC CARCINOGENESIS

artículo científico publicado en 1964

Effect of 5-fluoroorotic acid administration of the 32 P base composition, DNA-RNA hybridization properties, and labeling of polyadenylate-rich RNA in the cytoplasm of rat liver cells

artículo científico publicado en 1973

Effect of Chronic Administration of Mestranol, Tamoxifen, and Toremifene on Hepatic Ploidy in Rats ⬇️

artículo científico publicado el 1 de junio de 1998

Effect of Gamma Radiation on Dietary and Hormonal Induction of Enzymes in Rat Liver ⬇️

artículo científico

Effect of age on the formation of small-cell colonies in cultures of primary rat hepatocytes

scientific article published on 01 July 1993

Effect of dietary fat on the initiation of hepatocarcinogenesis by diethylnitrosamine or 2-acetylaminofluorene in rats ⬇️

artículo científico publicado el 1 de junio de 1991

Effect of hypolipidemic peroxisome proliferators on unscheduled DNA synthesis in cultured hepatocytes and on mutagenesis in Salmonella

artículo científico publicado en 1984

Effect of ribosome removal of rough microsomal composition and polysome attachment in vitro. Comparison of liver and kidney.

artículo científico publicado en 1974

Effect of the Inhibition of RNA Synthesis on in vitro Ovulation by Frog Ovaries ⬇️

artículo científico

Effect of the antihistamine, methapyrilene, as an initiator of hepatocarcinogenesis in female rats

scientific article published on 01 August 1989

Effect of the peroxisome proliferator perfluorodecanoic acid on the promotion of two-stage hepatocarcinogenesis in rats

scientific article published on 01 August 1993

Effect of the separate and combined administration of mestranol and phenobarbital on the development of altered hepatic foci expressing placental form of glutathione S-transferase in the rat.

artículo científico publicado en 1996

Effects of 5-azacytidine on dietary and hormone induction of serine dehydratase and tyrosine aminotransferase in rat liver

artículo científico publicado en 1972

Effects of 5-azacytidine on hepatic polyribosomes and maturation of ribosomal RNA.

artículo científico publicado en 1974

Effects of 5-azacytidine on nucleolar RNA and the preribosomal particles in Novikoff hepatoma cells

artículo científico publicado en 1975

Effects of altered [ADP-ribose]n metabolism on expression of fetal functions by adult hepatocytes

artículo científico publicado en 1982

Effects of chronic administration of tamoxifen and toremifene on DNA adducts in rat liver, kidney, and uterus

artículo científico publicado en 1997

Effects of extracellular matrix components on the growth and differentiation of cultured rat hepatocytes

artículo científico publicado en 1987

Effects of glucose, insulin, and cAMP on transcription of the serine dehydratase gene in rat liver

artículo científico publicado en 1991

Effects of phenobarbital on I-compounds in liver DNA as a function of age in male rats fed two different diets ⬇️

artículo científico publicado el 1 de enero de 1992

Effects of tamoxifen administration on the expression of xenobiotic metabolizing enzymes in rat liver

scientific article published on 01 April 1995

Effects of the Antiestrogens Tamoxifen, Toremifene, and ICI 182,780 on Endometrial Cancer Growth ⬇️

artículo científico publicado el 21 de octubre de 1998

Effects of tumor-promoting agents 12-O-tetradecanoylphorbol-13-acetate and phenobarbital on DNA synthesis of rat hepatocytes in primary culture

artículo científico publicado en 1987

Efficacy of CPT-11 (irinotecan) as a single agent in metastatic colorectal cancer

artículo científico publicado en 1996

Electron microscopic and time lapse studies of mitosis in cultured rat hepatocytes

artículo científico publicado en 1988

Endogenous carcinogenesis: the role of tumor promotion

artículo científico publicado en 1991

Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia

artículo científico publicado en 2010

Endoplasmic reticulum and phenotypic variability in normal and neoplastic liver.

artículo científico publicado en 1969

Enhanced efficacy of anti-VEGFR2/taxane therapy after progression on immune checkpoint inhibition (ICI) in patients (pts) with metastatic gastroesophageal adenocarcinoma (mGEA).

artículo científico publicado en 2020

Enhanced efficacy of anti-VEGFR2/taxane therapy after progression on immune checkpoint inhibition (ICI) in patients (pts) with metastatic gastroesophageal adenocarcinoma (mGEA).

artículo científico publicado en 2020

Environmental effects on glutathione-insulin transhydrogenase in rat liver ⬇️

artículo científico publicado el 1 de septiembre de 1976

Environmental modifiers in carcinogenesis

artículo científico publicado en 1982

Enzymatic and biochemical properties of a novel human serine dehydratase isoform

artículo científico publicado en 2006

Enzyme levels in rats adapted to 36-hour fasting

artículo científico publicado en 1966

Enzymes of carbohydrate and amino acid metabolism in liver, brain and kidney of Macaca mulatta

artículo científico publicado en 1971

Enzymes of glutathione metabolism as biochemical markers during hepatocarcinogenesis

artículo científico publicado en 1987

Enzymology of Highly Differentiated Hepatocellular Carcinomas1 ⬇️

artículo científico publicado el 1 de enero de 1976

Epidermal cancer associated with expression of human papillomavirus type 16 E6 and E7 oncogenes in the skin of transgenic mice

artículo científico publicado en 1993

Evidence for bile acid synthesis by transplantable hepatomas.

artículo científico publicado en 1974

Examination of glycosylated alpha 2u-globulin-containing medium for steroid-binding activity

artículo científico publicado en 1980

Expression of H-ras and c-myc protooncogenes in isolated gamma-glutamyl transpeptidase-positive rat hepatocytes and in hepatocellular carcinomas induced by diethylnitrosamine

scientific article published on 01 May 1986

Expression of albumin messenger RNA detected by in situ hybridization in preneoplastic and neoplastic lesions in rat liver

artículo científico publicado en 1986

Expression of c-myc in altered hepatic foci induced in rats by various single doses of diethylnitrosamine and promotion by 0.05% phenobarbital

artículo científico publicado en 1995

Expression of the c-raf protooncogene, gamma-glutamyltranspeptidase, and gap junction protein in rat liver neoplasms

artículo científico publicado en 1988

Extra-hepatic hepatocellular carcinoma presenting as obstructive jaundice

scientific article published on 19 October 2005

Extracellular matrix components influence DNA synthesis of rat hepatocytes in primary culture

artículo científico publicado en 1986

Factors predisposing to cancer

artículo científico publicado en 1981

Facts and theories concerning the mechanisms of carcinogenesis ⬇️

artículo científico publicado el 1 de junio de 1991

Falls: descriptive rates and circumstances in age-unspecified patients with locally advanced esophageal cancer

scientific article published on 24 May 2020

Fatal cicatricial mucous membrane pemphigoid of the trachea

artículo científico publicado en 1962

Feedback control of rat liver tryptophan pyrrolase. I. End product inhibition of trytophan pyrrolase activity.

artículo científico publicado en 1967

Fetal phenotypic expression by adult rat hepatocytes on collagen gel/nylon meshes ⬇️

artículo científico publicado el 1 de enero de 1979

Five-year data and prognostic factor analysis of oxaliplatin and irinotecan combinations for advanced colorectal cancer: N9741

artículo científico publicado en 2008

Focal and non-focal hepatic expression of placental glutathione S-transferase in carcinogen-treated rats

artículo científico publicado en 1994

Functional studies of polysome-membrane interactions in vitro

artículo científico publicado en 1973

Future directions in adjuvant therapy for stage III colon carcinoma.

artículo científico publicado en 2001

Gamma-glutamyl transpeptidase--its role in hepatocarcinogenesis

artículo científico publicado en 1985

Gemcitabine and oxaliplatin for metastatic pancreatic adenocarcinoma: a North Central Cancer Treatment Group phase II study.

artículo científico publicado en 2003

Gemcitabine and oxaliplatin for patients with advanced or metastatic pancreatic cancer: a North Central Cancer Treatment Group (NCCTG) phase I study

artículo científico publicado en 2002

Gene expression during multistage hepatocarcinogenesis

artículo científico publicado en 1988

Genes, chromosome loci and disease

artículo científico publicado el 1 de diciembre de 1975

Genetics and epigenetics of neoplasia: facts and theories

artículo científico publicado en 1985

Genome-wide loss of heterozygosity analysis of chemically induced rat hepatocellular carcinomas reveals elevated frequency of allelic imbalances on chromosomes 1, 6, 8, 11, 15, 17, and 20.

artículo científico publicado en 2000

Glucocorticoids stimulate CREB binding to a cyclic-AMP response element in the rat serine dehydratase gene

artículo científico publicado en 1999

Glucose repression and induction of enzyme synthesis in rat liver

artículo científico publicado en 1964

Growth of carcinogen-altered rat hepatocytes in the liver of syngeneic recipients promoted with phenobarbital

artículo científico publicado en 1985

HEPATOMAS IN TISSUE CULTURE COMPARED WITH ADAPTING LIVER IN VIVO

artículo científico publicado en 1964

Hazard assessment of chemical carcinogens: the impact of hormesis.

artículo científico publicado en 2000

Hepatic cyst formation in male rats partially hepatectomized as weanlings during short-term feeding of 2-acetylaminofluorene ⬇️

artículo científico publicado el 1 de enero de 1982

Hepatocarcinogenesis as a Problem in Developmental Biology ⬇️

artículo científico publicado el 1 de enero de 1980

Hepatocarcinogenicity of Estragole (1-Allyl-4-methoxybenzene) and 1′-Hydroxyestragole in the Mouse and Mutagenicity of 1′-Acetoxyestragole in Bacteria 2 ⬇️

artículo científico publicado el 1 de diciembre de 1976

Hepatocellular carcinomas of the albumin SV40 T-antigen transgenic rat display fetal-like re-expression of lgf2 and deregulation of H19.

artículo científico publicado en 2007

Hepatocyte death in hepatocarcinogenesis ⬇️

artículo científico publicado el 1 de julio de 1998

High incidence of HPV-associated head and neck cancers in FA deficient mice is associated with E7's induction of DNA damage through its inactivation of pocket proteins

artículo científico publicado en 2013

Hormonal Regulation of Phosphoenolpyruvate Carboxykinase in Primary Cultures of Adult-Rat Liver Parenchymal Cells ⬇️

artículo científico publicado el 15 de junio de 1978

Hormonal and developmental regulation of glycosylated α2u-globulin synthesis ⬇️

artículo científico publicado el 1 de mayo de 1980

Hormonal and nutritional effects on the binding of 125I-labeled anti-serine dehydratase Fab' to rat tissue polysomes

artículo científico publicado el 10 de agosto de 1976

Hormonal effects on enzyme activities in tissue culture and in whole animals

artículo científico publicado en 1967

Hormonal regulation and the effects of glucose on tyrosine aminotransferase activity in adult rat hepatocytes cultured on floating collagen membranes ⬇️

artículo científico publicado el 1 de junio de 1978

Hormonal regulation of glucokinase in primary cultures of adult rat hepatocytes ⬇️

artículo científico publicado el 25 de diciembre de 1979

Hormonal regulation of ornithine aminotransferase biosynthesis in rat liver and kidney ⬇️

artículo científico publicado el 30 de abril de 1977

Hormonal regulation of serine dehydratase gene expression in liver and kidney of the adrenalectomized rat

artículo científico publicado en 1991

Human gamma-glutamyl transpeptidase cDNA: comparison of hepatoma and kidney mRNA in the human and rat.

artículo científico publicado en 1989

Human liver serine dehydratase. cDNA cloning and sequence homology with hydroxyamino acid dehydratases from other sources

artículo científico publicado en 1989

Human papillomavirus 16 E5 oncogene contributes to two stages of skin carcinogenesis

artículo científico publicado en 2007

Human papillomavirus type 16 E6 and E7 oncoproteins act synergistically to cause head and neck cancer in mice

artículo científico publicado en 2010

Hypomethylation of the rat glutathione S-transferase pi (GSTP) promoter region isolated from methyl-deficient livers and GSTP-positive liver neoplasms ⬇️

artículo científico publicado el 1 de agosto de 1998

Identification of biomarkers that distinguish human papillomavirus (HPV)-positive versus HPV-negative head and neck cancers in a mouse model

artículo científico publicado en 2006

Identification of regions in the rat serine dehydratase gene responsible for regulation by cyclic AMP alone and in the presence of glucocorticoids

artículo científico publicado en 1992

Immunohistochemical demonstration of serine dehydratase in rat liver ⬇️

artículo científico publicado el 1 de febrero de 1975

Immunohistochemical localization and semi-quantitation of hepatic tamoxifen-DNA adducts in rats exposed orally to tamoxifen

artículo científico publicado en 2001

Impact of complete response to chemotherapy on overall survival in advanced colorectal cancer: results from Intergroup N9741.

artículo científico publicado en 2007

Implications of hormesis on the bioassay and hazard assessment of chemical carcinogens ⬇️

artículo científico publicado el 1 de mayo de 1998

Improved assay of 3-hydroxy-3-methylglutaryl coenzyme A reductase ⬇️

artículo científico publicado el 1 de julio de 1971

In vitro synthesis and processing of a precursor to ornithine aminotransferase ⬇️

artículo científico publicado el 25 de junio de 1982

Inability of red beet betalain pigments to initiate or promote hepatocarcinogenesis

artículo científico publicado en 1983

Incidental findings in imaging research: evaluating incidence, benefit, and burden

artículo científico publicado en 2010

Incorporation of bromodeoxyuridine in glutathione S-transferase-positive hepatocytes during rat multistage hepatocarcinogenesis

artículo científico publicado en 1994

Incorporation of label from 5-fluoroorotate into non-ribosomal cytoplasmic RNA in rat liver

artículo científico publicado en 1970

Increase of l-serine dehydratase activity under gluconeogenic conditions in adult-rat hepatocytes cultured on collagen gel/nylon mesh ⬇️

artículo científico publicado el 15 de septiembre de 1981

Increased activities of liver cathepsins T and D in carbon tetrachloride-treated rats

artículo científico publicado en 1984

Induction of a previously non-inducible enzyme in Morris hepatoma 9618A

scientific article published on 01 January 1970

Induction of altered hepatic foci in rats by the administration of hypolipidemic peroxisome proliferators alone or following a single dose of diethylnitrosamine

artículo científico publicado en 1986

Induction of hepatic aneuploidy in vivo by tamoxifen, toremifene and idoxifene in female Sprague-Dawley rats

artículo científico publicado en 1996

Induction of lipogenic enzymes in primary cultures of rat hepatocytes. Relationship between lipogenesis and carbohydrate metabolism

scientific article published on 01 November 1982

Influence of background genome on enzymatic characteristics of yellow (A v -, A vy -) mice

artículo científico publicado en 1973

Influence of dietary fat on the promotion of diethylnitrosamine-induced hepatocarcinogenesis in female rats

scientific article published on 01 April 1986

Inhibition of Ribosomal Ribonucleic Acid Maturation in Rat Liver by 5-Fluoroorotic Acid Resulting in the Selective Labeling of Cytoplasmic Messenger Ribonucleic Acid ⬇️

artículo científico publicado el 1 de noviembre de 1971

Inhibition of cyclic AMP-dependent induction of ornithine aminotransferase by simple carbohydrates in cultured hepatocytes

artículo científico publicado en 1987

Inhibition of ribosomal RNA maturation in Novikoff hepatoma cells by toyocamycin, tubercidin, and 6-thioguanosine

artículo científico publicado en 1974

Inhibition of ribosomal ribonucleic acid maturation by 5-azacytidine and 8-azaguanine in Novikoff hepatoma cells

artículo científico publicado en 1974

Inhibition of ribosomal ribonucleic acid maturation in Novikoff hepatoma cells by 5-fluorouracil and 5-fluorouridine

artículo científico publicado en 1973

Interaction of chemical carcinogens and drug-metabolizing enzymes in primary cultures of hepatic cells from the rat ⬇️

artículo científico publicado el 1 de diciembre de 1976

Interaction of glucagon and catecholamines in the regulation of serine dehydratase

artículo científico publicado en 1973

Interactions in the natural history of aging and carcinogenesis

artículo científico publicado el 1 de diciembre de 1978

Interactive cytogenetic effects on rat bone-marrow due to chronic ingestion of 2,5,2',5' and 3,4,3',4' PCBs

artículo científico publicado en 1992

Interrelationships of mammalian hormones and enzyme levels in vivo ⬇️

artículo científico publicado el 1 de enero de 1973

Intratumoral administration of a 1,2-dimyristyloxypropyl-3- dimethylhydroxyethyl ammonium bromide/dioleoylphosphatidylethanolamine formulation of the human interleukin-2 gene in the treatment of metastatic renal cell carcinoma

artículo científico publicado en 2004

Introductory remarks: membrane-polysome interactions

artículo científico publicado el 1 de enero de 1973

Isolation and characterization of rat liver free and membrane-bound polysomal messenger ribonucleoprotein particles

artículo científico publicado el 15 de noviembre de 1977

Isolation and characterization of the rat gene encoding ornithine aminotransferase

artículo científico publicado el 24 de septiembre de 1992

Isolation and fractionation of ribonucleic acid from the smooth endoplasmic reticulum of rat liver

scientific article published on 01 April 1966

Isolation and nucleotide sequence of the cDNA for rat liver serine dehydratase mRNA and structures of the 5' and 3' flanking regions of the serine dehydratase gene

artículo científico publicado en 1988

Isolation of γ-glutamyl transpeptidase positive hepatocytes during the early stages of hepatocarcinogenesis in the rat ⬇️

artículo científico publicado el 1 de enero de 1982

Karyotypic changes in a multistage model of chemical hepatocarcinogenesis in the rat

artículo científico publicado en 1996

L-tryptophan inhibition of tyrosine aminotransferase degradation in rat liver in vivo

artículo científico publicado en 1973

Labeling of cytoplasmic liver RNA by (6- 14 C)orotic and 5-fluoro(2- 14 C)orotic acids. Effect of several inhibitors.

artículo científico publicado en 1973

Lack of acetylaminofluorene--DNA adduct formation in enzyme-altered foci of rat liver

artículo científico publicado en 1988

Lack of expression of glutathione-S-transferase P, gamma-glutamyl transpeptidase, and alpha-fetoprotein messenger RNAs in liver tumors induced by peroxisome proliferators

artículo científico publicado en 1988

Levels of ornithine aminotransferase messenger RNA under conditions of cyclic AMP induction in cultured hepatocytes

artículo científico publicado en 1985

Limited sampling models for CPT-11, SN-38, and SN-38 glucuronide

artículo científico publicado en 2001

Liver tumor promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin is dependent on the aryl hydrocarbon receptor and TNF/IL-1 receptors

artículo científico publicado en 2014

Localization and hormonal control of serine dehydratase during metabolic acidosis differ markedly from those of phosphoenolpyruvate carboxykinase in rat kidney

artículo científico publicado en 2003

Localization of polysome-bound albumin and serine dehydratase in rat liver cell fractions

artículo científico publicado en 1973

Location and characterization of multiple glucocorticoid-responsive elements in the rat serine dehydratase gene

artículo científico publicado el 1 de septiembre de 1992

Long-lived Min mice develop advanced intestinal cancers through a genetically conservative pathway

artículo científico publicado en 2009

Loss of Dependence on Continued Expression of the Human Papillomavirus 16 E7 Oncogene in Cervical Cancers and Precancerous Lesions Arising in Fanconi Anemia Pathway-Deficient Mice

artículo científico publicado en 2016

METABOLIC ADAPTATIONS IN RAT HEPATOMAS. VI. SUBSTRATE-HORMONE RELATIONSHIPS IN TRYPTOPHAN PYRROLASE INDUCTION

artículo científico

METABOLIC REGULATORY CIRCUITS AND CARCINOGENESIS

artículo científico publicado en 1963

Maintenance of glucokinase activity in primary hepatocyte cultures

scientific article published on 01 May 1980

Maintenance of microsomal cytochromes b5 and P-450 in primary cultures of parenchymal liver cells on collagen membranes

artículo científico publicado en 1976

Mammary tumor induction in transgenic mice expressing an RNA-binding protein

artículo científico

Mechanisms in cellular metabolic regulation

artículo científico publicado en 1971

Medium term effects of a new 5HT3 antagonist, alosetron, in patients with carcinoid diarrhoea ⬇️

artículo científico publicado el 1 de mayo de 1998

Metabolic adaptations and the neoplastic cell

artículo científico

Metabolic adaptations during hepatocarcinogenesis: dietary induction of some enzymes of carbohydrate metabolism during 3'-methyl- and 2-methyl-N,N-dimethyl-4-aminoazobenzene feeding

artículo científico publicado en 1970

Metabolic adaptations in rat hepatomas. I. The effect of dietary protein on some inducible enzymes in liver and hepatoma 5123

scientific article published on 01 September 1961

Metabolic adaptations in rat hepatomas. II. Tryptophan pyrrolase and tyrosine alpha-ketoglutarate transaminase

scientific article published on 01 September 1961

Metabolic adaptations in rat hepatomas. III. Glucose-phosphate dehydrogenase and pyrimidine reductases

artículo científico

Metabolic adaptations in rat hepatomas. IV. Regulation of threonine and serine dehydrase

artículo científico publicado en 1963

Metabolic adaptations in rat hepatomas. V. Reciprocal relationship between threonine dehydrase and glucose-6-phosphate dehydrogenase

scientific article published on 01 March 1963

Metabolic adaptations in rat hepatomas: altered regulation of serine dehydratase synthesis by glucose and amino acids in hepatocellular carcinomas.

artículo científico publicado en 1970

Metabolic adaptations in rat hepatomas: some properties of apo-tryptophan pyrrolase of rat liver and two hepatocellular carcinomas

scientific article published on 01 January 1968

Methodology and utility of primary cultures of hepatocytes from experimental animals

artículo científico publicado en 1980

Microfilament accumulation and the transport of amino acids and glucose in adult rat hepatocytes cultured on collagen gel/nylon mesh

artículo científico publicado en 1981

Models of hepatocarcinogenesis in the rat--contrasts and comparisons

artículo científico publicado en 1986

Modulation of c-myc expression in the HL-60 cell line

scientific article published on 01 March 1984

Molecular cloning, sequence analysis, and expression in Escherichia coli of the cDNA for guanidinoacetate methyltransferase from rat liver

scientific journal article

Molecular pathogenesis of experimental liver cancer

artículo científico publicado en 1962

Mucinous appendiceal adenocarcinoma presenting 5 years after appendectomy

scientific article published on 01 April 2004

Multidisciplinary graduate training for biomedical science

artículo científico publicado en 1974

Multiple cell cycles occur in rat hepatocytes cultured in the presence of nicotinamide and epidermal growth factor ⬇️

artículo científico publicado el 1 de enero de 1991

Multiple mechanisms are responsible for altered expression of gap junction genes during oncogenesis in rat liver.

artículo científico publicado en 1994

Multiple polypeptide hormone expression in pancreatic islet cell carcinomas derived from phosphoenolpyruvatecarboxykinase-SV40 T antigen transgenic rats

artículo científico publicado en 2000

Multistage carcinogenesis--genetic and epigenetic mechanisms in relation to cancer prevention

artículo científico publicado en 1993

Multistage carcinogenesis: the Twenty-Second International Symposium of the Princess Takamatsu Cancer Research Fund ⬇️

artículo científico publicado el 1 de septiembre de 1992

Multistage hepatocarcinogenesis in the rat: insights into risk estimation

artículo científico publicado el 1 de enero de 1992

Mutational analysis of three tumor suppressor genes in two models of rat hepatocarcinogenesis.

artículo científico publicado en 1999

N-hydroxy metabolites of 2-acetylaminophenanthrene and 7-fluoro-2-acetylaminofluorene as proximate carcinogens in the rat

scientific article published on 01 November 1966

N-terminal acetylation of histone-like nascent peptides on rat liver polyribosomes in vitro

artículo científico publicado en 1974

Nakahara Memorial Lecture. Pathways of carcinogenesis--genetic and epigenetic

artículo científico publicado en 1991

Neoadjuvant 5-FU or Capecitabine Plus Radiation With or Without Oxaliplatin in Rectal Cancer Patients: A Phase III Randomized Clinical Trial

artículo científico publicado en 2015

Neoplasia: a somatic mutation or a heritable change in cytoplasmic membranes?

artículo científico publicado en 1974

New discoveries in oncology: potential applications to clinical practice

artículo científico publicado en 1985

Nitric oxide regulates tumor cell cross-talk with stromal cells in the tumor microenvironment of the liver

artículo científico publicado en 2008

Nuclear-labeling index analysis (NLIA), a software package used to perform accurate automation of cell nuclear-labeling index analysis on immunohistochemically stained rat liver samples

scientific article published on 01 August 2000

Number of ouabain-binding sites in fibroblasts from normal subjects and patients with cystic fibrosis

scientific article published on 01 January 1974

Nutritional regulation and tissue-specific expression of the serine dehydratase gene in rat.

artículo científico publicado en 1991

O-phosphorylethanolamine ammonia lyase, a new pyridoxal phosphate-dependent enzyme ⬇️

artículo científico

Octreotide inhibition of flushing and colonic motor dysfunction in carcinoid syndrome

artículo científico publicado el 1 de diciembre de 1997

On the passing of Gerald C. Mueller, MD, PhD (1920–2010).

artículo científico publicado en 2011

Oncogenes and human neoplasia

artículo científico publicado en 1986

Optimum doses of irinotecan

artículo científico publicado en 1999

Organization and characterization of the rat class 3 aldehyde dehydrogenase gene.

artículo científico publicado en 1993

Osteoporotic bone disease in the pyridoxine-deficient rat

scientific article published on 01 December 1972

Ovariectomy promotes the growth of altered hepatic foci after withdrawal and reintroduction of phenobarbital during hepatocarcinogenesis in rats

artículo científico publicado el 1 de octubre de 1992

Oxaloacetate induces DNA synthesis and mitosis in primary cultured rat hepatocytes in the absence of EGF

scientific article published on 01 June 1993

Pathology of mouse models of intestinal cancer: consensus report and recommendations

artículo científico publicado en 2003

Pathways of progression in hepatocarcinogenesis

artículo científico publicado en 2001

Peptide vaccination of patients with metastatic melanoma: improved clinical outcome in patients demonstrating effective immunization

artículo científico publicado en 2006

Phase 1 trial of Vismodegib and Erlotinib combination in metastatic pancreatic cancer

scientific article published on 21 November 2019

Phase 1b/II study of cancer stemness inhibitor napabucasin in combination with FOLFIRI +/- bevacizumab (bev) in metastatic colorectal cancer (mCRC) patients (pts)

scientific article published on 01 June 2017

Phase 2 study of bevacizumab plus erlotinib in patients with advanced hepatocellular cancer ⬇️

artículo científico publicado el 27 de septiembre de 2011

Phase I and pharmacokinetic study of irinotecan and docetaxel in patients with advanced solid tumors: preliminary evidence of clinical activity

scientific article published on 01 March 2000

Phase I and pharmacokinetic study of two different schedules of oxaliplatin, irinotecan, Fluorouracil, and leucovorin in patients with solid tumors

artículo científico publicado en 2003

Phase I and pharmacologic study of sequences of gemcitabine and the multitargeted antifolate agent in patients with advanced solid tumors

scientific article published on 01 April 2000

Phase I dose-finding and pharmacokinetic trial of irinotecan hydrochloride (CPT-11) using a once-every-three-week dosing schedule for patients with advanced solid tumor malignancy.

artículo científico publicado en 2000

Phase I evaluation of preirradiation chemotherapy with carmustine and cisplatin and accelerated radiation therapy in patients with high-grade gliomas.

artículo científico publicado en 1999

Phase I study of immunotherapy of hepatic metastases of colorectal carcinoma by direct gene transfer of an allogeneic histocompatibility antigen, HLA-B7 ⬇️

artículo científico publicado el 1 de mayo de 1997

Phase I study of the matrix metalloproteinase inhibitor, BAY 12-9566.

artículo científico publicado en 2001

Phase I trial of dolastatin-10 (NSC 376128) in patients with advanced solid tumors

scientific article published on 01 March 1999

Phase I trial of gemcitabine and CPT-11 given weekly for four weeks every six weeks

artículo científico publicado en 2001

Phase I trial of sequential administration of raltitrexed (Tomudex) and 5-iodo-2'-deoxyuridine (IdUrd).

artículo científico publicado en 2001

Phase I trial of temozolomide (NSC 362856) in patients with advanced cancer

artículo científico publicado en 1997

Phase II enzyme expression in rat liver in response to the antiestrogen tamoxifen

artículo científico publicado en 1996

Phase II study of Erlotinib (OSI-774) in patients with advanced hepatocellular cancer

artículo científico publicado en 2005

Phase II study of erlotinib in patients with advanced biliary cancer

artículo científico publicado en 2006

Phase II trial of irinotecan in patients with metastatic colorectal carcinoma ⬇️

artículo científico publicado el 1 de agosto de 1997

Phase III clinical trial of the combination of cisplatin, dacarbazine, and carmustine with or without tamoxifen in patients with advanced malignant melanoma

artículo científico publicado en 1999

Phase III noninferiority trial comparing irinotecan with oxaliplatin, fluorouracil, and leucovorin in patients with advanced colorectal carcinoma previously treated with fluorouracil: N9841.

artículo científico publicado en 2009

Phenobarbital-inducible aldehyde dehydrogenase in the rat. cDNA sequence and regulation of the mRNA by phenobarbital in responsive rats

scientific journal article

Pilot study of continuous-infusion 5-fluorouracil, oral leucovorin, and upper-abdominal radiation therapy in patients with locally advanced residual or recurrent upper gastrointestinal or extrapelvic colon cancer

artículo científico publicado en 1997

Plasma insulin-like growth factors, insulin-like binding protein-3, and outcome in metastatic colorectal cancer: results from intergroup trial N9741.

artículo científico publicado en 2008

Ploidy and karyotype of hepatocytes isolated from enzyme-altered foci in two different protocols of multistage hepatocarcinogenesis in the rat.

artículo científico publicado en 1989

Ploidy and specific karyotypic changes during promotion with phenobarbital, 2,5,2',5'-tetrachlorobiphenyl, and/or 3,4,3'4'-tetrachlorobiphenyl in rat liver

artículo científico publicado en 1992

Pocket Proteins Suppress Head and Neck Cancer ⬇️

artículo científico publicado el 11 de enero de 2012

Polyadenylate-containing RNA of polyribosomes isolated from rat liver and Morris hepatoma 7800

scientific article published on 01 January 1974

Polyamine degradation in foetal and adult bovine serum

artículo científico publicado en 1982

Polyribosomal attachment to rat liver and hepatoma endoplasmic reticulum in vitro. A method for its study

artículo científico publicado en 1971

Polysome interaction in vitro with smooth microsomal membranes from rat liver ⬇️

artículo científico publicado el 3 de diciembre de 1971

Population pharmacokinetic model for irinotecan and two of its metabolites, SN-38 and SN-38 glucuronide

artículo científico publicado en 2002

Predominant modifier of extreme liver cancer susceptibility in C57BR/cdJ female mice localized to 6 Mb on chromosome 17.

artículo científico publicado en 2009

Preliminary characterization of the rat class 3 aldehyde dehydrogenase gene.

artículo científico publicado en 1993

Preoperative hepatic artery chemoembolization followed by orthotopic liver transplantation for hepatocellular carcinoma

artículo científico publicado en 1999

Preparation of ribonuclease-free DNase I and -amylase

artículo científico publicado en 1973

Primary culture of parenchymal liver cells on collagen membranes. Morphological and biochemical observations

artículo científico publicado el 1 de agosto de 1975

Priming tissue-specific cellular immunity in a phase I trial of autologous dendritic cells for prostate cancer.

artículo científico publicado en 2000

Progression: the terminal stage in carcinogenesis

artículo científico publicado en 1989

Prolien synthesis and degradation in a minimal deviation hepatoma ⬇️

artículo científico publicado en 1962

Proliferation-associated differences in the spatial and temporal expression of gap junction genes in rat liver ⬇️

artículo científico publicado el 1 de julio de 1995

Promotion by dietary phenobarbital of hepatocarcinogenesis by 2-methyl-N,N-dimethyl-4-aminoazobenzene in the rat ⬇️

artículo científico publicado el 1 de enero de 1979

Properties of incomplete carcinogens and promoters in hepatocarcinogenesis

artículo científico publicado en 1982

Protein Degradation in Normal and Beige (Chediak-Higashi) Mice ⬇️

artículo científico publicado el 1 de febrero de 1978

Protein Phosphorylation of the Smooth and Rough Endoplasmic Reticulum in Normal and Neoplastic Liver of the Rat ⬇️

artículo científico publicado el 1 de junio de 1976

Protein acetylation

artículo científico publicado en 1982

Protein synthesis on rat liver polysome-membrane complexes formed in vitro and disposition of the discharges chains

artículo científico publicado en 1973

Protein turnover in microsomal subfractions of liver and Morris hepatomas 7800 and 9618A

artículo científico publicado en 1973

Proto-oncogene activation during chemically induced hepatocarcinogenesis in rodents

artículo científico

Proto-oncogene activation in multistage murine hepatocarcinogenesis

artículo científico

Purification and characterization of a factor catalyzing the conversion of the multiple forms of tyrosine aminotransferase from rat liver ⬇️

artículo científico publicado el 10 de agosto de 1980

Purification and characterization of a new thiol proteinase from rat kidney

artículo científico publicado en 1981

Putrescine-oxidase activity in adult bovine serum and fetal bovine serum ⬇️

artículo científico publicado el 1 de abril de 1979

Quantitation of multistage carcinogenesis in rat liver

artículo científico publicado en 1996

Quantitative analysis of dose- and time-dependent promotion of four phenotypes of altered hepatic foci by 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Sprague-Dawley rats

artículo científico publicado en 1999

Quantitative analysis of the time-dependent development of glucose-6-phosphatase-deficient foci in the livers of mice treated neonatally with diethylnitrosamine

scientific article published on 01 May 1981

Quantitative comparison of initiation and mutation phenotypes in hepatocytes of the analbuminemic rat.

artículo científico publicado en 1993

Quantitative evaluation of the promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin of hepatocarcinogenesis from diethylnitrosamine

artículo científico publicado en 1980

Quantitative stereologic study of the effects of varying the time between initiation and promotion on four histochemical markers in rat liver during hepatocarcinogenesis

artículo científico publicado en 1990

Quantitative stereological analysis of the effects of age and sex on multistage hepatocarcinogenesis in the rat by use of four cytochemical markers

artículo científico publicado en 1990

Quantitative stereological evaluation of four histochemical markers of altered foci in multistage hepatocarcinogenesis in the rat.

artículo científico publicado en 1987

Quantitative stereological studies of a 'selection' protocol of hepatocarcinogenesis following initiation in neonatal male and female rats

artículo científico publicado en 1997

Randomized controlled trial of reduced-dose bolus fluorouracil plus leucovorin and irinotecan or infused fluorouracil plus leucovorin and oxaliplatin in patients with previously untreated metastatic colorectal cancer: a North American Intergroup Tri

artículo científico publicado en 2006

Rapamycin inhibits anal carcinogenesis in two preclinical animal models

artículo científico publicado en 2010

Rapid uptake of dietary cholesterol by hyperplastic liver nodules and primary hepatomas

artículo científico publicado en 1973

Rat liver and hepatoma polysome-membrane interaction in vitro

artículo científico publicado en 1966

Rat liver serine dehydratase. Bacterial expression and two folding domains as revealed by limited proteolysis

artículo científico publicado en 1999

Rat serine dehydratase gene codes for two species of mRNA of which only one is translated into serine dehydratase

artículo científico publicado en 1990

Recent advances in the mechanism of hepatic carcinogenesis

artículo científico publicado en 1970

Reestablishment of cell polarity of rat hepatocytes in primary culture

artículo científico publicado en 1993

Regression of metastatic carcinoid tumor after valvular surgery for carcinoid heart disease

artículo científico publicado en 1997

Regulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible expression of aldehyde dehydrogenase in hepatoma cells

artículo científico publicado el 1 de noviembre de 1992

Regulation of ATP-citrate lyase in primary cultures of adult rat hepatocytes ⬇️

artículo científico publicado el 10 de diciembre de 1979

Regulation of gene expression in primary cultures of adult rat hepatocytes on collagen gels ⬇️

artículo científico publicado el 1 de enero de 1980

Regulation of ornithine aminotransferase by cyclic AMP and glucose in primary cultures of adult rat hepatocytes

scientific article published on 01 March 1985

Regulation of ornithine aminotransferase mRNA levels in rat kidney by estrogen and thyroid hormone ⬇️

artículo científico publicado el 10 de febrero de 1983

Regulation of the expression of some genes for enzymes of glutathione metabolism in hepatotoxicity and hepatocarcinogenesis.

artículo científico publicado en 1989

Regulation of the expression of the serine dehydratase gene in the kidney and liver of the rat

scientific article published on 01 July 1990

Regulation of the synthesis of serine dehydratase isozymes

scientific article published on 01 January 1970

Regulatory effects of nicotinamide on tryptophan pyrrolase synthesis in rat liver in vivo

artículo científico publicado en 1968

Regulatory elements for the tissue-specific expression of the rat serine dehydratase-encoding gene

artículo científico publicado el 21 de octubre de 1992

Relation between fat malabsorption and transit abnormalities in human carcinoid diarrhea

artículo científico publicado en 1996

Relationships of bioassay data on chemicals to their toxic and carcinogenic risk for humans

artículo científico publicado en 1980

Report of a multicenter phase II trial testing a combination of biweekly bevacizumab and daily erlotinib in patients with unresectable biliary cancer: a phase II Consortium study

artículo científico publicado en 2010

Response of hepatic enzyme activities to castration and sarcoma 37 growth in different mouse genotypes

artículo científico publicado el 1 de agosto de 1972

Response of several hepatic adaptive enzymes to a shift from low to high protein diet in intact and adrenalectomized rats

artículo científico publicado en 1971

Reversal by aminoguanidine of the inhibition of proliferation of human fibroblasts by spermidine and spermine ⬇️

artículo científico publicado el 1 de julio de 1978

Reversible alteration in the expression of the gap junctional protein connexin 32 during tumor promotion in rat liver and its role during cell proliferation

artículo científico publicado en 1990

Review article: the stages of gastrointestinal carcinogenesis--application of rodent models to human disease

artículo científico publicado en 2000

Ribonuclease activity of pancreatic extracts

scientific article published on 01 December 1977

Role of Ultraviolet Radiation in Papillomavirus-Induced Disease

artículo científico publicado en 2016

Role of altered hepatic foci in the stages of carcinogenesis

artículo científico

Role of insulin, glucose, and cyclic GMP in the regulation of glucokinase in cultured hepatocytes

artículo científico publicado en 1981

SOME BIOCHEMICAL ESSENTIALS OF MALIGNANCY.

artículo científico publicado en 1963

STEREO: A program on a PC-Windows 95 platform for recording and evaluating quantitative stereologic investigations of multistage hepatocarcinogenesis in rodents ⬇️

artículo científico publicado el 1 de abril de 1998

STUDIES ON THE INDUCTION AND REPRESSION OF ENZYMES IN RAT LIVER. 3. INDUCTION OF ORNITHINE DELTA-TRANSAMINASE AND THREONINE DEHYDRASE BY ORAL INTUBATION OF FREE AMINO ACIDS

artículo científico publicado en 1965

STUDIES ON THE INDUCTION AND REPRESSION OF ENZYMES IN RAT LIVER. I. INDUCTION OF THREONINE DEHYDRASE AND ORNITHINE-DELTA-TRANSAMINASE BY ORAL INTUBATION OF CASEIN HYDROLYSATE

artículo científico

STUDIES ON THE INDUCTION AND REPRESSION OF ENZYMES IN RAT LIVER. II. CARBOHYDRATE REPRESSION OF DIETARY AND HORMONAL INDUCTION OF THREONINE DEHYDRASE AND ORNITHINE DELTA-TRANSAMINASE

artículo científico publicado en 1964

SUBSTRATE AND HORMONAL INTERACTIONS IN THE REGULATION OF ENZYME LEVELS IN RAT HEPATOMAS

scientific article published on 01 January 1963

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

artículo científico publicado en 2012

Safety and activity of temsirolimus and bevacizumab in patients with advanced renal cell carcinoma previously treated with tyrosine kinase inhibitors: a phase 2 consortium study

artículo científico publicado en 2015

Safety, pharmacokinetics, and pharmacodynamic properties of oral DEBIO1143 (AT-406) in patients with advanced cancer: results of a first-in-man study.

artículo científico publicado en 2015

Selective loss of nucleoside carrier expression in rat hepatocarcinomas.

artículo científico publicado en 2000

Separation of putrescine oxidase and spermidine oxidase in foetal bovine serum with the aid of a specific radioactive assay of spermidine oxidase

artículo científico publicado en 1980

Sequence of the precursor to rat ornithine aminotransferase deduced from a cDNA clone

scientific journal article

Sequence of the rat serine dehydratase gene

artículo científico publicado en 1988

Serum ribonuclease levels in patients with cystic fibrosis

artículo científico publicado el 1 de abril de 1978

Short-term fasting and the reversal of the stage of promotion in rat hepatocarcinogenesis: role of cell replication, apoptosis, and gene expression

artículo científico publicado en 1999

Small cell colonies appear in the primary culture of adult rat hepatocytes in the presence of nicotinamide and epidermal growth factor

artículo científico publicado en 1992

Sodium butyrate preserves aspects of the differentiated phenotype of normal adult rat hepatocytes in culture

artículo científico publicado en 1988

Some aspects of the developmental biology of neoplasia

artículo científico publicado en 1968

Some biochemical and histochemical properties of human liver serine dehydratase

artículo científico publicado en 2005

Some enzyme patterns of Morris hepatoma 9618A under controlled feeding schedules

scientific article published on 01 September 1969

Specific chromosomal changes in albumin simian virus 40 T antigen transgenic rat liver neoplasms ⬇️

artículo científico publicado el 15 de agosto de 1997

Specific gene expression during compensatory renal hypertrophy in the rat

artículo científico publicado en 1987

Spermidine oxidase in human pregnancy serum. Probable identity with diamine oxidase

artículo científico publicado en 1982

Squamous epithelial hyperplasia and carcinoma in mice transgenic for the human papillomavirus type 16 E7 oncogene.

artículo científico publicado en 1996

Stage of tumor progression, progressor agents, and human risk

artículo científico publicado en 1993

Stage-specific gene expression during hepatocarcinogenesis in the rat.

artículo científico publicado en 1996

Static and dynamic aspects of amino acid pools in rat liver and Morris hepatomas 9618A and 7800

artículo científico publicado en 1974

Stimulation of DNA synthesis in primary cultures of adult rat hepatocytes by sodium butyrate

artículo científico publicado en 1987

Stimulatory effect of dietary lipid and cholestyramine on hepatic HMG CoA reductase

artículo científico publicado en 1972

Structure and function of rat liver polysome populations. I. Complexity, frequency distribution, and degree of uniqueness of free and membrane-bound polysomal polyadenylate-containing RNA populations

artículo científico publicado en 1981

Structure and function of rat liver polysome populations. II. Characterization of polyadenylate-containing mRNA associated with subpopulations of membrane-bound particles

artículo científico publicado en 1982

Structure of the 5' flanking region of class 3 aldehyde dehydrogenase in the rat.

artículo científico publicado en 1994

Structure–Activity Relationships for Triphenylethylene Antiestrogens on Hepatic Phase-I and Phase-II Enzyme Expression ⬇️

artículo científico publicado el 1 de agosto de 1998

Studies of tamoxifen as a promoter of hepatocarcinogenesis in female Fischer F344 rats

artículo científico publicado en 1994

Studies on a 32S component of nuclear RNA.

artículo científico publicado en 1967

Studies on basic charged molecules and cell membranes in cystic fibrosis

scholarly article by P J Benke et al published 1 September 1971 in Proceedings of the Society for Experimental Biology and Medicine

Studies on the Mechanism of Enzyme Induction in Rat Liver ⬇️

artículo científico publicado en 1961

Studies on the conversion of multiple forms of tyrosine aminotransferase in rat liver ⬇️

artículo científico publicado el 1 de noviembre de 1976

Studies on the induction and repression of enzymes in rat liver. Characteristics of the L-tryptophan and cortisone-mediated induction of serine dehydratase in the livers of intact and adrenalectomized rats

artículo científico publicado en 1975

Studies on the induction and repression of enzymes in rat liver. Characterization and metabolic regulation of multiple forms of tyrosine aminotransferase

artículo científico publicado en 1973

Studies on the induction and repression of enzymes in rat liver. IV. Effects of cortisone and phenobarbital

artículo científico publicado en 1966

Studies on the induction and repression of enzymes in rat liver. V. Regulation of the rate of synthesis and degradation of serine dehydratase by dietary amino acids and glucose

artículo científico publicado en 1968

Studies on the induction and repression of enzymes in rat liver. VI. Some properties and the metabolic regulation of two isozymic forms of serine dehydratase

article by Inoue H et al published 1 April 1971 in Journal of Biological Chemistry

Studies on the mechanism of 5-fluoroorotic acid inhibition of serine dehydratase induction

artículo científico publicado en 1974

Studies on the mechanism of carbohydrate repression in rat liver

artículo científico publicado en 1966

Studies on the mechanism of template stability. I. The effect of actinomycin on the base composition and sedimentation of 32P-labeled RNA in rat liver

artículo científico publicado en 1966

Studies on the mechanism of template stability: cytoplasmic DNA-like RNA in hepatocellular carcinomas

artículo científico publicado en 1970

Studies on the mechanism of the stimulation of tyrosine aminotransferase activity in vivo by pyrimidine analogs: the role of enzyme synthesis and degradation

artículo científico publicado en 1973

Studies on the role of adenosine 3',5'-monophosphate during glucose repression in rat liver

scientific article published on 01 October 1973

Studies on the synthesis of plasma membrane proteins of fibroblasts from patients with cystic fibrosis ⬇️

artículo científico publicado el 1 de agosto de 1975

Study of the separate and combined effects of the non-planar 2,5,2',5'- and the planar 3,4,3',4'-tetrachlorobiphenyl in liver and lymphocytes in vivo

artículo científico publicado en 1991

Superinduction of 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible expression of aldehyde dehydrogenase by the inhibition of protein synthesis

artículo científico publicado en 1991

Survey of some enzyme patterns in transplantable Reuber mouse hepatomas.

artículo científico publicado en 1971

Symposium: Cell-carcinogen interaction in tissue culture. Introduction ⬇️

artículo científico publicado el 1 de diciembre de 1976

Systematic oscillations in metabolic activity in rat liver and hepatomas. Survey of normal diploid and other hepatoma lines

artículo científico publicado en 1969

Systematic oscillations in metabolic activity in rat liver and hepatomas: effect of hydrocortisone, glucagon, and adrenalectomy on diploid and other hepatoma lines

scientific article published on 01 November 1969

Systematic oscillations in metabolic activity in rat liver and in hepatomas. I. Morris hepatoma No. 7793

artículo científico publicado en 1966

Systematic oscillations in tyrosine transaminase and other metabolic functions in liver of normal and adrenalectomized rats on controlled feeding schedules

artículo científico publicado en 1968

THE AUTOMATED ASSAY OF COMPLETE ENZYME REACTION RATES. I. METHODS AND RESULTS

scientific article published on 01 December 1964

Tamoxifen induces hepatic aneuploidy and mitotic spindle disruption after a single in vivo administration to female Sprague-Dawley rats

artículo científico publicado en 1994

Template stability of some enzymes in rat liver and hepatoma

artículo científico publicado en 1965

Teratogenic effects of 5-bromodexyuridine on the external morphology of Drosophila melanogaster

artículo científico publicado en 1973

The McArdle Laboratory for Cancer Research

scientific article published on 01 March 1987

The McArdle Laboratory for Cancer Research: the first fifty years

scientific article published on 01 January 1990

The Membron: A Functional Hypothesis for the Translational Regulation of Genetic Expression ⬇️

artículo científico publicado el 1 de enero de 1974

The N-hydroxy metabolites of N-methyl-4-aminoazobenzene and related dyes as proximate carcinogens in the rat and mouse ⬇️

artículo científico publicado el 1 de septiembre de 1979

The aryl hydrocarbon receptor is required for developmental closure of the ductus venosus in the neonatal mouse.

artículo científico publicado en 2004

The association in vitro of polyribosomes with ribonuclease-treated derivatives of hepatic rough endoplasmic reticulum. Characteristics of the membrane binding sites and factors influencing association ⬇️

artículo científico publicado el 1 de noviembre de 1971

The automated assay of complete enzyme reaction rates. II. Digital readout and data processing of linear rates

artículo científico publicado en 1968

The bicarbonate ion is essential for efficient DNA synthesis by primary cultured rat hepatocytes

scientific article published on 01 July 1991

The binding of cyclic nucleotides to membranes of the endoplasmic reticulum of normal and neoplastic rat liver ⬇️

artículo científico publicado el 1 de julio de 1976

The biochemical morphology and morphogenesis of hepatomas.

artículo científico publicado en 1968

The comparative enzymology and cell origin of rat hepatomas. I. Deoxycytidylate deaminase and thymine degradation

artículo científico publicado en 1960

The comparative enzymology and cell origin of rat hepatomas. II. Glutamate dehydrogenase, choline oxidase, and glucose-6-phosphatase

artículo científico publicado en 1960

The comparative enzymology and cell origin of rat hepatomas. III. Some enzymes of amino acid metabolism

artículo científico

The control of DNA synthesis in primary cultures of hepatocytes from adult and young rats: interactions of extracellular matrix components, epidermal growth factor, and the cell cycle

scientific article published on 01 February 1987

The effect of amino acid composition of serum-free medium on DNA synthesis in primary hepatocyte cultures in the presence of epidermal growth factor

artículo científico publicado en 1995

The effect of choline and methionine deficiencies on the number and volume percentage of altered hepatic foci in the presence or absence of diethylnitrosamine initiation in rat liver

artículo científico publicado en 1990

The effect of gamma radiation and actinomycin on cortisone induction of liver enzymes

artículo científico publicado en 1972

The effect of nicotinamide on unscheduled DNA synthesis in cultured hepatocytes

artículo científico publicado en 1980

The effect of pyrimidine analogues and tryptophan on enzyme synthesis and degradation in rat liver

artículo científico publicado en 1970

The effect of short-term fasting, phenobarbital and refeeding on apoptotic loss, cell replication and gene expression in rat liver during the promotion stage ⬇️

artículo científico publicado el 1 de agosto de 1998

The effect of sodium butyrate on tyrosine aminotransferase induction in primary cultures of normal adult rat hepatocytes

artículo científico publicado en 1988

The effect of spermidine and spermine on proliferation in vitro of fibroblasts from normal and cystic fibrosis patients

artículo científico publicado el 1 de mayo de 1976

The effect of tamoxifen and two of its non-isomerizable fixed-ring analogs on multistage rat hepatocarcinogenesis

artículo científico publicado en 1996

The effect of the dose of diethylnitrosamine on the initiation of altered hepatic foci in neonatal female rats

artículo científico publicado en 1993

The effect of the format of administration and the total dose of phenobarbital on altered hepatic foci following initiation in female rats with diethylnitrosamine

artículo científico publicado en 1991

The effect of two periods of short-term fasting during the promotion stage of hepatocarcinogenesis in rats: the role of apoptosis and cell proliferation

artículo científico publicado en 1997

The effect of various treatments in vitro and in vivo on the binding of 125I-labeled anti-rat serum albumin Fab' to rat tissue polyribosomes

artículo científico publicado el 10 de agosto de 1976

The effects of dose and duration of administration on the promotion index of phenobarbital in multistage hepatocarcinogenesis in the rat.

artículo científico publicado en 1988

The expression and metabolic activity of cytochrome P-450 isozymes in control and phenobarbital-induced primary cultures of rat hepatocytes

scientific article published on 01 May 1988

The expression of the myc proto-oncogene in a dimethylsulfoxide resistant HL-60 cell line

artículo científico publicado en 1984

The human papillomavirus type 16 E6 gene alone is sufficient to induce carcinomas in transgenic animals

artículo científico publicado en 1999

The in vitro synthesis of protein

artículo científico publicado en 1955

The initiation-promotion-progression model of rat hepatocarcinogenesis

artículo científico publicado en 1993

The instability of tumor promotion in relation to human cancer risk

artículo científico publicado en 1995

The interaction of external and internal controls on enzyme levels and hepatoma.

artículo científico publicado en 1965

The interconversion of multiple forms of tyrosine aminotransferase

artículo científico publicado en 1975

The interconversion of multiple forms of tyrosine aminotransferase ⬇️

artículo científico publicado el 22 de julio de 1975

The mechanism of thioacetamide-induced apoptosis in the L37 albumin-SV40 T-antigen transgenic rat hepatocyte-derived cell line occurs without DNA fragmentation ⬇️

artículo científico publicado el 1 de octubre de 1998

The metabolism of O-phosphorylethanolamine in animal tissues. I. O-phosphorylethanolamine phospho-lyase: partial purification and characterization

artículo científico publicado en 1970

The metabolism of O-phosphorylethanolamine in animal tissues. II. Metabolic regulation of O-phosphorylethanolamine phospho-lyase in vivo

artículo científico publicado en 1970

The molecular biology of carcinogenesis

artículo científico publicado en 1993

The molecular determinants of carcinogenesis

artículo científico publicado en 1986

The multistage nature of chemically induced hepatocarcinogenesis in the rat.

artículo científico publicado en 1994

The natural history and dose-response characteristics of enzyme-altered foci in rat liver following phenobarbital and diethylnitrosamine administration

scientific article published on 01 January 1984

The natural history of carcinogenesis: implications of experimental carcinogenesis in the genesis of human cancer

artículo científico publicado en 1981

The natural history of neoplasia. Newer insights into an old problem ⬇️

artículo científico publicado el 1 de noviembre de 1977

The natural history of neoplastic development:The relation of experimental models to human cancer ⬇️

artículo científico publicado el 15 de marzo de 1982

The ornithine aminotransferase gene in gyrate atrophy of the retina: analysis of expression and gross structure of this gene in cultured fibroblasts

artículo científico publicado en 1989

The oxidation of glycolic acid by a liver enzyme

artículo científico publicado en 1954

The phenotypic stability of altered hepatic foci: effect of the short-term withdrawal of phenobarbital and of the long-term feeding of purified diets after the withdrawal of phenobarbital

artículo científico publicado en 1986

The phenotypic stability of altered hepatic foci: effects of withdrawal and subsequent readministration of phenobarbital.

artículo científico publicado en 1986

The pleiotropic phenotype of Apc mutations in the mouse: allele specificity and effects of the genetic background.

artículo científico publicado en 2008

The quantitation of altered hepatic foci during multistage hepatocarcinogenesis in the rat: Transforming growth factor α expression as a marker for the stage of progression ⬇️

artículo científico publicado el 29 de junio de 1995

The quantitative analysis and stability of histochemical markers of altered hepatic foci in rat liver following initiation by diethylnitrosamine administration and promotion with phenobarbital

artículo científico publicado en 1985

The regulation of 4 forms of tyrosine aminotransferase in adult and developing rat liver.

artículo científico publicado en 1971

The regulation of beta-hydroxy-beta-methylglutaryl coenzyme A reductase in Morris hepatomas 5123C, 7800, and 9618A.

artículo científico publicado en 1971

The regulation of ornithine aminotransferase synthesis by glucagon in the rat ⬇️

artículo científico publicado el 1 de mayo de 1976

The regulation of serine dehydratase and glucose-6-phosphatase in hyperplastic nodules of rat liver during diethylnitrosamine and N-2-fluorenylacetamide feeding ⬇️

artículo científico publicado el 1 de abril de 1975

The role of hormones in glucose repression in rat liver

artículo científico publicado en 1969

The role of receptors in multistage carcinogenesis

artículo científico publicado en 1995

The role of the stages of initiation and promotion in phenotypic diversity during hepatocarcinogenesis in the rat.

artículo científico publicado en 1992

The selectivity and stoicheiometry of membrane binding sites for polyribosomes, ribosomes and ribosomal subunits in vitro ⬇️

artículo científico publicado el 1 de marzo de 1975

The significance of selected biochemical markers in the characterization of putative initiated cell populations in rodent liver

artículo científico publicado en 1985

The stability of events in the natural history of neoplasia ⬇️

artículo científico publicado el 1 de diciembre de 1977

The stability of the neoplastic state: introduction ⬇️

artículo científico publicado el 1 de diciembre de 1977

The stages of initiation and promotion in hepatocarcinogenesis

artículo científico publicado en 1980

The synthesis and degradation of rat liver and kidney fructose bisphosphatase in Vivo ⬇️

artículo científico publicado el 1 de mayo de 1979

The tamoxifen controversy--clinical chemopreventive agent and experimental carcinogen

artículo científico publicado en 1995

The translational inhibitor cycloheximide represses growth factor depletion-induced apoptosis in an alb-SV40T transgenic rat liver cell line

artículo científico publicado en 1996

Three-dimensional reconstruction from serial sections in PC-Windows platform by using 3D_Viewer.

artículo científico publicado en 2004

Transcriptional control of ornithine aminotransferase synthesis in rat kidney by estrogen and thyroid hormone

artículo científico publicado en 1984

Transcriptional regulation and localization of the tissue-specific induction of epoxide hydrolase by lead acetate in rat kidney

artículo científico publicado en 1991

Transcriptional regulation of c-myc during chemically induced differentiation of HL-60 cultures

artículo científico publicado en 1985

Transgene expression and repression in transgenic rats bearing the phosphoenolpyruvate carboxykinase-simian virus 40 T antigen or the phosphoenolpyruvate carboxykinase-transforming growth factor-alpha constructs

artículo científico publicado en 1999

Transgenic hepatocarcinogenesis in the rat

artículo científico publicado en 1994

Translational and pretranslational control of ornithine aminotransferase synthesis in rat liver ⬇️

artículo científico publicado el 25 de mayo de 1983

Translational regulatory mechanisms in neoplasia in vivo

artículo científico publicado el 1 de enero de 1976

Transport of labelled compounds in control and cystic-fibrosis cells in vitro.

artículo científico publicado en 1972

Treatment of colorectal peritoneal carcinomatosis with systemic chemotherapy: a pooled analysis of north central cancer treatment group phase III trials N9741 and N9841.

artículo científico publicado en 2011

Treatment of neuroendocrine cancer metastatic to the liver: the role of ablative techniques.

artículo científico publicado en 2005

Triggering the cellular change to neoplasia ⬇️

artículo científico publicado el 1 de abril de 1984

Tumor promotion as a target for estrogen/antiestrogen effects in rat hepatocarcinogenesis ⬇️

artículo científico publicado el 1 de enero de 1991

Tumor-promoting barbiturates act on DNA repair of cultured hepatocytes

artículo científico publicado en 1986

Turnover of 3'-polyadenylate-containing RNA in livers from aged, partially hepatectomized, neonatal, and Morris 5123C hepatoma-bearing rats

scientific article published on 01 May 1980

U.S.-Japan Cooperative Cancer Research Program Conference. Glutathione S-transferase and carcinogenesis

artículo científico publicado en 1988

US pivotal studies of irinotecan in colorectal carcinoma

artículo científico publicado el 1 de agosto de 1998

Ultrastructural and biochemical characteristics of endoplasmic reticulum fractions of the Morris 7800 and Reuber H-35 hepatomas

artículo científico publicado en 1970

Ultrastructure of adult rat hepatocytes cultured on floating collagen membranes ⬇️

artículo científico publicado el 1 de junio de 1978

Unscheduled DNA synthesis in cells from N-2-fluorenylacetamide-induced hyperplastic nodules of rat liver maintained in a primary culture system ⬇️

artículo científico publicado el 1 de diciembre de 1975

Unscheduled DNA synthesis induced by procarcinogens in suspensions and primary cultures of hepatocytes on collagen membranes ⬇️

artículo científico publicado el 1 de julio de 1978

Updated efficacy and toxicity analysis of irinotecan and oxaliplatin (IROX) : intergroup trial N9741 in first-line treatment of metastatic colorectal cancer

artículo científico publicado en 2007

Ureteral obstruction in cancer patients: a qualitative study

artículo científico publicado en 2015

Use of KW-2189, a DNA minor groove-binding agent, in patients with hepatocellular carcinoma: a north central cancer treatment group (NCCTG) phase II clinical trial

artículo científico publicado en 2007

Use of a low-speed, iso-density percoll centrifugation method to increase the viability of isolated rat hepatocyte preparations

artículo científico publicado en 1986

Use of primary cultures of adult rat hepatocytes on collagen gel-nylon mesh to evaluate carcinogen-induced unscheduled DNA synthesis

artículo científico publicado en 1980

Use of rat liver altered focus models for testing chemicals that have completed two-year carcinogenicity studies

artículo científico publicado en 1989

Variability in the oral bioavailability of all-trans-retinoic acid

artículo científico publicado en 1993

Variation of hepatic malic enzyme capacity with hepatoma susceptibility in mice of different genotypes

scientific article published on 01 September 1972

Vitamin D status in patients with stage IV colorectal cancer: findings from Intergroup trial N9741.

artículo científico publicado en 2011

Whole Blood mRNA Expression-Based Prognosis of Metastatic Renal Cell Carcinoma

artículo científico publicado en 2017

all-trans retinoic acid: a dose-seeking study in solid tumors

scientific article published on 01 December 1993

alpha 2 micro-Globulin in the rat. The regulation of the appearance of multiple forms in vivo and in primary cultures of adult hepatocytes ⬇️

artículo científico publicado el 10 de octubre de 1979

p53 Loss synergizes with estrogen and papillomaviral oncogenes to induce cervical and breast cancers

artículo científico publicado en 2008

γ-Glutamyltranspeptidase-positive (GGT+) hepatocytes from carcinogen-treated rats isolated by magnetic beads ⬇️

artículo científico publicado el 1 de julio de 1991

Lista de obras de

3′,5′-cyclic AMP and the release of polysone-bound proteins in vitro ⬇️

A Mouse Model for Human Anal Cancer ⬇️

A North Central Cancer Treatment Group Phase II trial of 9-aminocamptothecin in previously untreated patients with measurable metastatic colorectal carcinoma

A Phase I study of bizelesin (NSC 615291) in patients with advanced solid tumors.

A Phase I trial of the farnesyl protein transferase inhibitor R115777 in combination with gemcitabine and cisplatin in patients with advanced cancer

A Phase II study of high-dose paclitaxel in patients with advanced neuroendocrine tumors

A Prospective Genome-Wide Study of Prostate Cancer Metastases Reveals Association of Wnt Pathway Activation and Increased Cell Cycle Proliferation with Primary Resistance to Abiraterone Acetate-Prednisone.

A clonal growth model: time-course simulations of liver foci growth following penta- or hexachlorobenzene treatment in a medium-term bioassay.

A comparison of polysomal messenger ribonucleoprotein particles from normal and neoplastic rat liver ⬇️

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

A method for the comparative study of replicative DNA synthesis in GGT-positive and GGT-negative hepatocytes in primary culture isolated from carcinogen-treated rats

A method to quantitate the relative initiating and promoting potencies of hepatocarcinogenic agents in their dose-response relationships to altered hepatic foci

A new thiol proteinase from rat liver

A partial characterization of human fibroblast plasma membranes isolated by the fluorescein mercuric acetate method of Barland and Schroeder

A phase 2 consortium (P2C) trial of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) for advanced adenocarcinoma of the pancreas

A phase I and pharmacokinetic study of a powder-filled capsule formulation of oral irinotecan (CPT-11) given daily for 5 days every 3 weeks in patients with advanced solid tumors

A phase I and pharmacologic study of pyrazoloacridine (NSC 366140) and carboplatin in patients with advanced cancer

A phase I and pharmacologic study of sequences of the proteasome inhibitor, bortezomib (PS-341, Velcade), in combination with paclitaxel and carboplatin in patients with advanced malignancies

A phase I and pharmacologic trial of two schedules of the proteasome inhibitor, PS-341 (bortezomib, velcade), in patients with advanced cancer

A phase I study of radiation therapy and twice-weekly gemcitabine and cisplatin in patients with locally advanced pancreatic cancer

A phase I study of sequential irinotecan and 5-fluorouracil/leucovorin

A phase I trial of ISIS 2503, an antisense inhibitor of H-ras, in combination with gemcitabine in patients with advanced cancer.

A phase I trial of the novel farnesyl protein transferase inhibitor, BMS-214662, in combination with paclitaxel and carboplatin in patients with advanced cancer.

A phase IB study of the pharmacokinetics of gemcitabine and pemetrexed, when administered in rapid sequence to patients with advanced solid tumors

A phase II safety and efficacy study of the vascular endothelial growth factor receptor tyrosine kinase inhibitor pazopanib in patients with metastatic urothelial cancer

A phase II study of ABT-510 (thrombospondin-1 analog) for the treatment of metastatic melanoma

A phase II study of intravenous 6-thioguanine (NSC-752) in advanced colorectal carcinoma

A phase II trial of 17-allylamino-17- demethoxygeldanamycin in patients with hormone-refractory metastatic prostate cancer

A phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with hormone-refractory metastatic prostate cancer

A potent modifier of liver cancer risk on distal mouse chromosome 1: linkage analysis and characterization of congenic lines.

A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer.

A role for HPV16 E5 in cervical carcinogenesis

A semipurified diet that suppresses phenobarbital promotion of hepatocarcinogenesis in the rat

A software package to improve image quality and isolation of objects of interest for quantitative stereology studies of rat hepatocarcinogenesis

ADP-ribosyltransferase activity in cultured hepatocytes. Interactions with DNA repair ⬇️

ALTERED TEMPLATE STABILITY: THE MOLECULAR MASK OF MALIGNANCY?

Abnormal cholesterol uptake, storage, and synthesis in the livers of 2-acetylaminofluorene-fed rats

Abnormal proteins in Drosophila melanogaster subsequent to 5-bromodeoxyuridine administration

Accumulation of actin microfilaments in adult rat hepatocytes cultured on collagen gel/nylon mesh

Acetylated polyamines as substrates for human pregnancy serum diamine oxidase

Acetylation of nascent polypeptide chains on rat liver polyribosomes in vivo and in vitro ⬇️

Acetylation of ribosome-associated proteins in vitro by an acetyltransferase bound to rat liver ribosomes ⬇️

Action of actinomycin D on tryptophan uptake in the adrenalectomized rat and its effect on induction of tryptophan pyrrolase and tyrosine transaminase in liver

Activities of benzphetamine N-demethylase and aryl hydrocarbon hydroxylase in cells isolated from gamma-glutamyl transpeptidase-positive foci and surrounding liver

Adjuvant external beam radiation therapy with concurrent chemotherapy in the management of gallbladder carcinoma

Adventures in hepatocarcinogenesis

Aging and cancer: some general thoughts

Aging lowers steady-state antioxidant enzyme and stress protein expression in primary hepatocytes

Alteration of ribosomal precursor RNA in Novikoff hepatoma cells by 5-azacytidine. Studies on methylation of 45S and 32S RNA.

Alterations in enzymes of amino acid catabolism in livers of rats bearing the Morris 7800 hepatoma ⬇️

Alterations in specific gene expression and focal neoplastic growth during spontaneous hepatocarcinogenesis in albumin-SV40 T antigen transgenic rats

Alterations in the maturation and structure of ribosomal precursor RNA in Novikoff hepatoma cells induced by 5-fluorocytidine

Altered hepatic foci: their role in murine hepatocarcinogenesis

Amino acid-rich medium (Leibovitz L-15) enhances and prolongs proliferation of primary cultured rat hepatocytes in the absence of serum.

An approach to the determination of the relative potencies of chemical agents during the stages of initiation and promotion in multistage hepatocarcinogenesis in the rat.

An approach to the development of a short-term whole-animal bioassay to distinguish initiating agents (incomplete carcinogens), promoting agents, complete carcinogens, and noncarcinogens in rat liver

An energy-dependent activation of trypttophan pyrrolase

An enzymic study on the cellular origin of the DUNNING and the NOVIKOFF hepatomas in the rat ⬇️

An examination of rat liver smooth endoplasmic reticulum membranes for the presence of associated messenger RNA

An improved stereologic method for three-dimensional estimation of particle size distribution from observations in two dimensions and its application

An initiation-promotion assay in rat liver as a potential complement to the 2-year carcinogenesis bioassay

An international, multicenter phase II trial of bortezomib in patients with hepatocellular carcinoma.

Analbuminemic rats

Androgen Receptor Variant AR-V9 Is Coexpressed with AR-V7 in Prostate Cancer Metastases and Predicts Abiraterone Resistance.

Animal models of neoplastic development

Application of quantitative stereology to the evaluation of enzyme-altered foci in rat liver.

Application of quantitative stereology to the evaluation of phenotypically heterogeneous enzyme-altered foci in the rat liver

BIOCHEMICAL LESIONS IN MINIMAL DEVIATION HEPATOMAS

Biallelic expression of the H19 gene during spontaneous hepatocarcinogenesis in the albumin SV40 T antigen transgenic rat

Biochemical and immunologic studies on the native and deglycosylated forms of gamma-glutamyltranspeptidase of rat kidney

Biochemical characterisation of stages of hepatocarcinogenesis after a single dose of diethylnitrosamine ⬇️

Biochemical events during initiation of rat hepatocarcinogenesis

Biochemical markers associated with the stages of promotion and progression during hepatocarcinogenesis in the rat ⬇️

Bioinformatics approaches for cross-species liver cancer analysis based on microarray gene expression profiling

Biological and Enzymatic Events in Chemical Carcinogenesis ⬇️

Biological markers characterizing the development of preneoplastic and neoplastic lesions in rodent liver

Breast cancer

Building quantitative stereology data files with scion image, a public domain image processing and analysis software

Cancer advisory board