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Lista de obras de Stephan R. Targan

2007 annual research and education meeting of the Spondyloarthritis Research and Therapy Network (SPARTAN).

artículo científico publicado en 2008

6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease.

artículo científico publicado en 2002

6-thioguanine can cause serious liver injury in inflammatory bowel disease patients

artículo científico publicado en 2003

A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF.

artículo científico publicado en 2016

A Multidisciplinary Approach to Biopsychosocial Care for Adults With Inflammatory Bowel Disease: A Pilot Study

artículo científico publicado en 2018

A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition

artículo científico publicado en 2016

A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study of Brodalumab in Patients With Moderate-to-Severe Crohn's Disease

artículo científico publicado en 2016

A case of steroid-dependent myeloid granulocytic sarcoma masquerading as Crohn's disease

artículo científico publicado en 2011

A distal region in the interferon-gamma gene is a site of epigenetic remodeling and transcriptional regulation by interleukin-2.

artículo científico publicado en 2004

A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease

artículo científico publicado en 1990

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

artículo científico publicado en 2006

A genome-wide search identifies potential new susceptibility loci for Crohn's disease

artículo científico publicado en 1999

A new syndrome of Crohn's disease and pachydermoperiostosis in a family

scientific article published on 01 January 1997

A novel NOD2/CARD15 haplotype conferring risk for Crohn disease in Ashkenazi Jews

artículo científico publicado en 2003

A phase I study of visilizumab, a humanized anti-CD3 monoclonal antibody, in severe steroid-refractory ulcerative colitis

artículo científico publicado en 2007

A pilot study of adalimumab in infliximab-allergic patients

artículo científico publicado en 2004

A prospective analysis of clinical variables, serologic factors, and outcome of ileal pouch-anal anastomosis in patients with backwash ileitis

scientific article published on July 2010

A prospective evaluation of the long-term outcome of ileal pouch-anal anastomosis in patients with inflammatory bowel disease-unclassified and indeterminate colitis

artículo científico publicado en 2009

A prospective multivariate analysis of clinical factors associated with pouchitis after ileal pouch-anal anastomosis

artículo científico publicado en 2007

A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

artículo científico publicado en 2016

A role for BATF3 in TH9 differentiation and T-cell-driven mucosal pathologies

artículo científico publicado en 2019

A role for TNF-alpha and mucosal T helper-1 cytokines in the pathogenesis of Crohn's disease

scientific article published on 01 December 1997

A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group.

artículo científico publicado en 1997

A soluble factor produced by lamina propria mononuclear cells is required for TNF-alpha enhancement of IFN-gamma production by T cells

scientific article published on 01 October 1999

A validated web-based tool to display individualised Crohn's disease predicted outcomes based on clinical, serologic and genetic variables

artículo científico publicado en 2015

A147 RESPONSE AND REMISSION AFTER 16 WEEKS OF USTEKINUMAB– AN ALL PATIENTS ANALYSIS FROM THE UNITI CROHN’S STUDIES

A85 EFFICACY AND SAFETY OF DOSE ADJUSTMENT AND DELAYED RESPONSE TO USTEKINUMAB IN MODERATE–SEVERE CROHN’S DISEASE: RESULTS FROM THE IM-UNITI MAINTENANCE STUDY

ANCA pattern and LTA haplotype relationship to clinical responses to anti-TNF antibody treatment in Crohn's disease

artículo científico publicado en 2001

ANTI-TUMOR NECROSIS FACTOR-α THERAPY IN CROHN'S DISEASE: A MAGIC BULLET FINALLY HITS ITS MARK.

artículo científico publicado en 1996

Abatacept for Crohn's disease and ulcerative colitis

artículo científico publicado en 2012

Activation of human NKCC by moderate exercise: increased frequency of NK cells with enhanced capability of effector--target lytic interactions ⬇️

artículo científico publicado el 1 de agosto de 1981

Additional evidence of linkage between Crohn's disease and a putative locus on chromosome 12.

artículo científico publicado en 1999

Age of diagnosis influences serologic responses in children with Crohn's disease: a possible clue to etiology?

scientific article published on May 2009

Altered intestinal ACE2 levels are associated with inflammation, severe disease and response to anti-cytokine therapy in IBD

artículo científico publicado en 2020

American gastroenterological association consensus development conference on the use of biologics in the treatment of inflammatory bowel disease, June 21-23, 2006.

artículo científico publicado en 2007

An engineered human antibody to TNF (CDP571) for active Crohn's disease: a randomized double-blind placebo-controlled trial

artículo científico publicado en 2001

An open-label pilot study of low-dose thalidomide in chronically active, steroid-dependent Crohn's disease.

artículo científico publicado en 1999

An open-label pilot study using thioguanine as a therapeutic alternative in Crohn's disease patients resistant to 6-mercaptopurine therapy

artículo científico publicado en 2001

Analysis of intestinal lymphocytes in mouse colitis mediated by transfer of CD4+, CD45RBhigh T cells to SCID recipients

scientific article published on 01 April 1997

Analysis of sequential substages of the natural killer cell lethal hit

scientific article published on 01 January 1985

Andrographis paniculata extract (HMPL-004) for active ulcerative colitis

artículo científico publicado en 2012

Anti-CD2O chimeric monoclonal antibody (rituximab) treatment of immune-mediated thrombocytopenia associated with Crohn's disease

artículo científico publicado en 2003

Anti-CD3 antibody visilizumab is not effective in patients with intravenous corticosteroid-refractory ulcerative colitis

artículo científico publicado en 2010

Anti-flagellin (CBir1) phenotypic and genetic Crohn's disease associations.

artículo científico publicado en 2007

Anti-neutrophil cytoplasmic antibodies in ulcerative colitis

artículo científico publicado en 1991

Anti-outer membrane of porin C and anti-I2 antibodies in indeterminate colitis

artículo científico publicado en 2006

Antibiotics for Treatment of Clostridium difficile Infection in Hospitalized Patients with Inflammatory Bowel Disease

artículo científico publicado en 2014

Antibodies to CBir1 flagellin define a unique response that is associated independently with complicated Crohn's disease.

artículo científico publicado en 2005

Antibodies to I2 predict clinical response to fecal diversion in Crohn's disease

artículo científico publicado en 2006

Antineutrophil cytoplasmic antibody correlates with chronic pouchitis after ileal pouch-anal anastomosis

scientific article published on 01 May 1995

Antineutrophil cytoplasmic antibody subtypes in children and adolescents after ileal pouch-anal anastomosis for ulcerative colitis

scientific article published on 01 April 1998

Assessing health status in inflammatory bowel disease using a novel single-item numeric rating scale

artículo científico publicado en 2012

Assessing inflammatory bowel disease-associated antibodies in Caucasian and First Nations cohorts.

artículo científico publicado en 2011

Association of Ribonuclease T2 Gene Polymorphisms With Decreased Expression and Clinical Characteristics of Severity in Crohn's Disease

artículo científico publicado en 2017

Association of antibody responses to microbial antigens and complications of small bowel Crohn's disease

artículo científico publicado en 2004

Association of antineutrophil cytoplasmic antibodies with resistance to treatment of left-sided ulcerative colitis: results of a pilot study

scientific article published on 01 May 1996

B lymphocyte-induced maturation protein-1 contributes to intestinal mucosa homeostasis by limiting the number of IL-17-producing CD4+ T cells.

artículo científico publicado en 2012

Bacterial flagellin is a dominant antigen in Crohn disease.

artículo científico publicado en 2004

Biologic therapy of inflammatory bowel disease.

artículo científico publicado en 2002

Blockade of cytotoxic T-lymphocyte antigen-4 by ipilimumab results in dysregulation of gastrointestinal immunity in patients with advanced melanoma ⬇️

artículo científico publicado el 24 de noviembre de 2010

Both preoperative perinuclear antineutrophil cytoplasmic antibody and anti-CBir1 expression in ulcerative colitis patients influence pouchitis development after ileal pouch-anal anastomosis

artículo científico publicado en 2008

CC chemokine receptor 9 expression defines a subset of peripheral blood lymphocytes with mucosal T cell phenotype and Th1 or T-regulatory 1 cytokine profile

artículo científico publicado en 2003

CCR9-positive lymphocytes and thymus-expressed chemokine distinguish small bowel from colonic Crohn's disease.

artículo científico publicado en 2001

CD161 DEFINES EFFECTOR T CELLS THAT EXPRESS LIGHT AND RESPOND TO TL1A-DR3 SIGNALING.

artículo científico publicado en 2011

CD2 mediates activation of the IFN‐γ intronic STAT binding region in mucosal T cells ⬇️

artículo científico publicado el 1 de mayo de 2003

CD28 costimulation augments IL-2 secretion of activated lamina propria T cells by increasing mRNA stability without enhancing IL-2 gene transactivation

scientific article published on 01 June 1999

CD56 marks an effector T cell subset in the human intestine

artículo científico publicado en 2007

Case report: evidence for transplacental transfer of maternally administered infliximab to the newborn

artículo científico publicado en 2006

Cathelicidin signaling via the Toll-like receptor protects against colitis in mice

artículo científico publicado en 2011

Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor

artículo científico publicado en 2016

Certolizumab pegol

artículo científico publicado en 2008

Challenges in IBD Research: updating the scientific agendas

artículo científico publicado en 2003

Characterization of genetic loci that affect susceptibility to inflammatory bowel diseases in African Americans

artículo científico publicado en 2015

Clinical Factors Associated with the Development of Crohn's Disease in Inflammatory Bowel Disease-unclassified Patients Undergoing Ileal Pouch-anal Anastomosis

artículo científico publicado en 2016

Clinical utility of serodiagnostic testing in suspected pediatric inflammatory bowel disease

scientific article published on 01 March 2001

Clinical, serologic, and genetic factors associated with pyoderma gangrenosum and erythema nodosum in inflammatory bowel disease patients

artículo científico publicado en 2014

Colectomy with Permanent End Ileostomy Is More Cost-Effective than Ileal Pouch-Anal Anastomosis for Crohn's Colitis

artículo científico publicado en 2015

Colonic Phenotypes Are Associated with Poorer Response to Anti-TNF Therapies in Patients with IBD.

artículo científico publicado en 2017

Colonoscopy during an attack of severe ulcerative colitis

scholarly article by F Shanahan et al published September 1991 in The American Journal of Gastroenterology

Colorectal cancer screening and surveillance in Crohn's colitis

artículo científico publicado en 2012

Combination of genetic and quantitative serological immune markers are associated with complicated Crohnʼs disease behavior ⬇️

artículo científico publicado el 9 de marzo de 2011

Combination of innate and adaptive immune alterations increased the likelihood of fibrostenosis in Crohn's disease

artículo científico publicado en 2010

Combined Immunosuppression Impairs Immunogenicity to Tetanus and Pertussis Vaccination Among Patients with Inflammatory Bowel Disease

artículo científico publicado en 2015

Constitutive TL1A (TNFSF15) Expression on Lymphoid or Myeloid Cells Leads to Mild Intestinal Inflammation and Fibrosis ⬇️

artículo científico publicado el 11 de enero de 2011

Constitutive TL1A expression under colitogenic conditions modulates the severity and location of gut mucosal inflammation and induces fibrostenosis

artículo científico publicado en 2011

Controversies in ulcerative colitis: a survey comparing decision making of experts versus community gastroenterologists

artículo científico publicado en 2008

Correction: Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population

correction of a scientific article; published on 30 May 2019

Crohn's disease-associated genetic marker is seen in medically unresponsive ulcerative colitis patients and may be associated with pouch-specific complications

artículo científico publicado en 1999

Crohn's ileitis after liver transplantation from a living related donor with Crohn's disease

artículo científico publicado en 2004

Current limitations of IBD treatment: where do we go from here?

artículo científico publicado en 2006

Cytokine and anti-cytokine therapies in prevention or treatment of fibrosis in IBD

artículo científico publicado en 2016

Cytotoxic lymphocytes in human intestinal mucosa

Daclizumab, a humanised monoclonal antibody to the interleukin 2 receptor (CD25), for the treatment of moderately to severely active ulcerative colitis: a randomised, double blind, placebo controlled, dose ranging trial

artículo científico publicado en 2006

Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis.

artículo científico publicado en 2017

Defective generation of tetanus-specific antibody-producing B cells after in vivo immunization of Crohn's disease and ulcerative colitis patients

scientific article published on 01 June 1985

Defective memory B cell formation in patients with inflammatory bowel disease following tetanus toxoid booster immunization.

artículo científico publicado en 1987

Defects in mucosal immunity leading to ulcerative colitis

artículo científico publicado en 2005

Definition of a secondary target cell trigger during natural killer cell cytotoxicity: possible role of phospholipase A2

scientific article published on 01 December 1987

Definition of ocular antigens in ciliary body and retinal ganglion cells by the marker antibody pANCA.

artículo científico publicado en 1999

Detection of antisynthetic mannoside antibodies (ASigmaMA) reveals heterogeneity in the ASCA response of Crohn's disease patients and contributes to differential diagnosis, stratification, and prediction

artículo científico publicado en 2007

Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD

artículo científico publicado en 2020

Diagnostic accuracy of serological assays in pediatric inflammatory bowel disease

artículo científico publicado en 1998

Differences in the management of Crohn's disease among experts and community providers, based on a national survey of sample case vignettes

artículo científico publicado en 2007

Differential Levels of Tl1a Affect the Expansion and Function of Regulatory T Cells in Modulating Murine Colitis

artículo científico publicado en 2016

Direct signaling of TL1A-DR3 on fibroblasts induces intestinal fibrosis in vivo

artículo científico publicado en 2020

Distinct IFNG methylation in a subset of ulcerative colitis patients based on reactivity to microbial antigens

artículo científico publicado en 2011

Distinct Methylation of IFNG in the Gut

artículo científico publicado en 2009

Distinct associations of HLA class II genes with inflammatory bowel disease.

artículo científico publicado en 1993

Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNF-alpha and ligation of Fas antigen ⬇️

artículo científico publicado el 1 de noviembre de 1995

Does infliximab influence surgical morbidity of ileal pouch-anal anastomosis in patients with ulcerative colitis?

artículo científico publicado en 2007

Does preoperative immunosuppression influence unplanned hospital readmission after surgery in patients with Crohn's disease?

artículo científico publicado en 2012

Dominant role for TL1A/DR3 pathway in IL-12 plus IL-18-induced IFN-gamma production by peripheral blood and mucosal CCR9+ T lymphocytes

artículo científico publicado en 2005

Double-Balloon Endoscopy in Crohn Disease: A Tertiary Referral Center Experience

artículo científico publicado en 2020

Early hepatic nodular hyperplasia and submicroscopic fibrosis associated with 6-thioguanine therapy in inflammatory bowel disease.

artículo científico publicado en 2004

Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease.

artículo científico publicado en 1999

Efficacy of mycophenolate mofetil in patients failing 6-mercaptopurine or azathioprine therapy for Crohn's disease

scientific article published on 01 February 2000

Elevated flagellin-specific immunoglobulins in Crohn's disease

artículo científico publicado en 2004

Elevated platelet count before ileal pouch-anal anastomosis for ulcerative colitis is associated with the development of chronic pouchitis

artículo científico publicado en 2005

Elevated serum anti-flagellin antibodies implicate subclinical bowel inflammation in ankylosing spondylitis: an observational study.

scientific article published on 26 October 2013

Enhanced CBir1-specific innate and adaptive immune responses in Crohn's disease

artículo científico publicado en 2008

Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips.

artículo científico publicado en 2017

Enhanced neutrophil chemiluminescence in familial Mediterranean fever

artículo científico publicado en 1988

Enhanced peripheral blood T-cell cytotoxicity in inflammatory bowel disease.

artículo científico publicado en 1989

Enhancer role of STAT5 in CD2 activation of IFN-gamma gene expression

artículo científico publicado en 2004

Epithelial endoplasmic reticulum stress orchestrates a protective IgA response

scientific article published on 01 March 2019

Erratum: Corrigendum: Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scholarly article published in Nature Genetics

Erratum: Corrigendum: The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD With the European Crohn's and Colitis Organization: When to Start, When to Stop, Which Drug to Choose and How to Predict Respo

article

Erratum: Corrigendum: Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study

scholarly article published in Nature Genetics

Erratum: Genome-wide association identifies multiple ulcerative colitis susceptibility loci

scholarly article published in Nature Genetics

Erratum: Sustained TL1A (TNFSF15) expression on both lymphoid and myeloid cells leads to mild spontaneous intestinal inflammation and fibrosis (DOI: 10.1556/EuJMI.3.2013.1.2)

artículo científico publicado en 2013

Evaluation of Serologic Disease Markers in a Population-Based Cohort of Patients with Ulcerative Colitis and Crohn's Disease

article

Evidence for involvement of serine proteases in the late stages of the natural killer cell lytic reaction

artículo científico publicado en 1986

Ex vivo induction of mRNA in human whole blood as a new platform of drug and dietary supplement development

artículo científico publicado en 2008

Ex vivo simulation of IgG Fc and T-cell receptor functions: an application to inflammatory bowel disease.

artículo científico publicado en 2008

Expression and regulation of the chemokine receptor CXCR3 on lymphocytes from normal and inflammatory bowel disease mucosa.

artículo científico publicado en 2004

Expression of a novel autoantibody defined by the VH3-15 gene in inflammatory bowel disease and Campylobacter jejuni enterocolitis

artículo científico publicado en 1994

Extended Dose Ipilimumab with a Peptide Vaccine: Immune Correlates Associated with Clinical Benefit in Patients with Resected High-Risk Stage IIIc/IV Melanoma ⬇️

artículo científico publicado el 24 de noviembre de 2010

Factors predictive of response to cyclosporin treatment for severe, steroid-resistant ulcerative colitis

artículo científico publicado en 2000

Familial empirical risks for inflammatory bowel disease: differences between Jews and non-Jews

artículo científico publicado en 1993

Familial expression of anti-Escherichia coli outer membrane porin C in relatives of patients with Crohn's disease

artículo científico publicado en 2006

Familial expression of anti-Saccharomyces cerevisiae mannan antibodies in affected and unaffected relatives of patients with Crohn's disease

artículo científico publicado en 2000

Family history and serology predict Crohn's disease after ileal pouch-anal anastomosis for ulcerative colitis

artículo científico publicado en 2007

Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

artículo científico publicado en 2010

Functional signaling of membrane-bound TL1A induces IFN-gamma expression

artículo científico publicado en 2010

Future biologic targets for IBD: potentials and pitfalls

artículo científico publicado en 2010

Future therapeutic approaches for inflammatory bowel diseases

artículo científico publicado en 2011

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease

artículo científico publicado en 2016

Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease

artículo científico publicado en 2009

Genetic markers may predict disease behavior in patients with ulcerative colitis

artículo científico publicado en 1997

Genetic predictors of medically refractory ulcerative colitis

scientific journal article

Genetic variants synthesize to produce paneth cell phenotypes that define subtypes of Crohn's disease.

artículo científico publicado en 2013

Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease

artículo científico publicado en 2010

Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease.

artículo científico publicado en 2016

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

artículo científico publicado en 2008

Genome-wide association identifies multiple ulcerative colitis susceptibility loci

artículo científico publicado en 2010

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

artículo científico publicado en 2007

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

artículo científico publicado en 2010

Glycosylation of Immunoglobulin G Associates With Clinical Features of Inflammatory Bowel Diseases

artículo científico publicado en 2018

HLA class II haplotype associations with inflammatory bowel disease in Jewish (Ashkenazi) and non-Jewish caucasian populations

artículo científico publicado en 2000

HMPL-004 (Andrographis paniculata extract) prevents development of murine colitis by inhibiting T-cell proliferation and TH1/TH17 responses

artículo científico publicado en 2013

Hermansky-Pudlak syndrome: an immunologic assessment of 15 cases

artículo científico publicado en 1988

High incidence of anergy in inflammatory bowel disease patients limits the usefulness of PPD screening before infliximab therapy

artículo científico publicado en 2004

High level perinuclear antineutrophil cytoplasmic antibody (pANCA) in ulcerative colitis patients before colectomy predicts the development of chronic pouchitis after ileal pouch-anal anastomosis

artículo científico publicado en 2001

High levels of Crohn's disease-associated anti-microbial antibodies are present and independent of colitis in chronic granulomatous disease

artículo científico publicado en 2011

High-frequency haplotypes in the X chromosome locus TLR8 are associated with both CD and UC in females

scientific article published on March 2009

High-level serum antibodies to bacterial antigens are associated with antibiotic-induced clinical remission in Crohn's disease: a pilot study

artículo científico publicado en 2004

High-titer antineutrophil cytoplasmic antibodies in type-1 autoimmune hepatitis ⬇️

artículo científico publicado el 1 de abril de 1995

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

artículo científico publicado en 2012

Human NK cells licensed by killer Ig receptor genes have an altered cytokine program that modifies CD4+ T cell function

artículo científico publicado en 2014

Human intestinal epithelial cells express interleukin-10 through Toll-like receptor 4-mediated epithelial-macrophage crosstalk

artículo científico publicado en 2014

Human monoclonal antibodies against Clostridium difficile toxins A and B inhibit inflammatory and histologic responses to the toxins in human colon and peripheral blood monocytes

artículo científico publicado en 2013

Human mucosal T-cell cytotoxicity.

artículo científico publicado en 1988

Human mucosal cytotoxic effector cells

artículo científico publicado en 1987

Hypoalbuminemia and Bandemia Predict Failure of Infliximab Rescue Therapy in Acute Severe Ulcerative Colitis

artículo científico publicado en 2020

IBD-associated TL1A gene (TNFSF15) haplotypes determine increased expression of TL1A protein

artículo científico publicado en 2009

IFNG rs1861494 polymorphism is associated with IBD disease severity and functional changes in both IFNG methylation and protein secretion

artículo científico publicado en 2014

IL-23 receptor (IL-23R) gene protects against pediatric Crohn's disease

artículo científico publicado en 2007

IL23R haplotypes provide a large population attributable risk for Crohn's disease

artículo científico publicado en 2008

Identification of a novel bacterial sequence associated with Crohn's disease

artículo científico publicado en 2000

Identification of a novel mycobacterial histone H1 homologue (HupB) as an antigenic target of pANCA monoclonal antibody and serum immunoglobulin A from patients with Crohn's disease

artículo científico publicado en 1999

Identification of a prodromal period in Crohn's disease but not ulcerative colitis

artículo científico publicado en 2000

Identification of histone H1 as a cognate antigen of the ulcerative colitis-associated marker antibody pANCA.

artículo científico publicado en 2000

Ileal Gene Expression Data from Crohn's Disease Small Bowel Resections Indicate Distinct Clinical Subgroups

artículo científico publicado en 2019

Immunologic mechanisms in intestinal diseases

artículo científico publicado en 1987

Immunopathogenesis of inflammatory bowel disease

artículo científico publicado en 2008

Immunosuppression impairs response to pneumococcal polysaccharide vaccination in patients with inflammatory bowel disease

artículo científico publicado en 2009

Increased immune reactivity predicts aggressive complicating Crohn's disease in children

artículo científico publicado en 2008

Increased neutrophil receptors for and response to the proinflammatory bacterial peptide formyl-methionyl-leucyl-phenylalanine in Crohn's disease.

artículo científico publicado en 1989

Inflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiome

Inflammatory bowel disease diagnosis, evaluation and classification: state-of-the art approach

artículo científico publicado en 2007

Inflammatory bowel disease serologies in ankylosing spondylitis patients: a pilot study

artículo científico publicado en 2009

Infliximab for the treatment of fistulas in patients with Crohn's disease

artículo científico publicado en 1999

Infliximab in the treatment of medically refractory indeterminate colitis

artículo científico publicado en 2003

Infliximab in the treatment of severe, steroid-refractory ulcerative colitis: a pilot study.

artículo científico publicado en 2001

Infliximab induces potent anti-inflammatory and local immunomodulatory activity but no systemic immune suppression in patients with Crohn's disease

scientific article published on 01 April 2001

Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis

artículo científico publicado en 2014

Inhibition of cytotoxicity by sulfasalazine. II. Sulfasalazine and sulfapyridine inhibit different stages of the NK and NKCF lytic processes

artículo científico publicado en 1986

Initial experience with wireless capsule enteroscopy in the diagnosis and management of inflammatory bowel disease.

artículo científico publicado en 2004

Insights into IBD Pathogenesis

artículo científico publicado en 2009

Insights into TL1A and IBD Pathogenesis ⬇️

artículo científico publicado el 1 de enero de 2011

Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population

preprint published 25 September 2016

Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.

artículo científico publicado en 2018

Intercellular adhesion molecule 1 gene associations with immunologic subsets of inflammatory bowel disease

artículo científico publicado en 1995

Intestinal immunity and inflammation: recent progress

artículo científico publicado en 1986

Introductory Words About TL1A/DR3 ⬇️

artículo científico publicado el 1 de enero de 2011

K562 killing by K, IL 2-responsive NK, and T cells involves different effector cell post-binding trigger mechanisms

LIGHT expression by mucosal T cells may regulate IFN-gamma expression in the intestine

artículo científico publicado en 2004

LIGHT is constitutively expressed on T and NK cells in the human gut and can be induced by CD2-mediated signaling

artículo científico publicado en 2005

Lack of an association between polymorphisms of the T-cell receptor alpha-chain and ulcerative colitis

artículo científico publicado en 1989

Lack of effect of intravenous administration on time to respond to azathioprine for steroid-treated Crohn's disease

article

Late-Onset Crohn's Disease Is A Subgroup Distinct in Genetic and Behavioral Risk Factors With UC-Like Characteristics

artículo científico publicado en 2018

Linkage of Crohn's disease to the major histocompatibility complex region is detected by multiple non-parametric analyses

artículo científico publicado en 1999

Linkage of Crohn's disease-related serological phenotypes: NFKB1 haplotypes are associated with anti-CBir1 and ASCA, and show reduced NF-kappaB activation

artículo científico publicado en 2008

Long-term efficacy and safety of ustekinumab for Crohn's disease through the second year of therapy.

artículo científico publicado en 2018

Long-term outcomes of thalidomide in refractory Crohn's disease

artículo científico publicado en 2014

MAGI2 genetic variation and inflammatory bowel disease

artículo científico publicado en 2009

Malassezia Is Associated with Crohn's Disease and Exacerbates Colitis in Mouse Models

artículo científico publicado en 2019

Marker antibody expression stratifies Crohn's disease into immunologically homogeneous subgroups with distinct clinical characteristics

artículo científico publicado en 2000

Markers of intestinal inflammation in patients with ankylosing spondylitis: a pilot study

artículo científico publicado en 2012

Mast cell and neuroendocrine cytoplasmic autoantigen(s) detected by monoclonal pANCA antibodies

artículo científico publicado en 2000

Measurement of tumor necrosis factor alpha mRNA in small numbers of cells by quantitative polymerase chain reaction

artículo científico publicado en 1993

Medical treatment of inflammatory bowel disease.

artículo científico publicado en 1992

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scientific journal article

Microbial induction of inflammatory bowel disease associated gene TL1A (TNFSF15) in antigen presenting cells

artículo científico publicado en 2009

Microbiota activation and regulation of innate and adaptive immunity

artículo científico publicado en 2014

Microbiota-Induced TNF-like Ligand 1A Drives Group 3 Innate Lymphoid Cell-Mediated Barrier Protection and Intestinal T Cell Activation during Colitis

artículo científico publicado en 2018

Modeling Intestinal Epithelial Response to Interferon-γ in Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids

artículo científico publicado en 2020

Modulation of ongoing human immunoglobulin synthesis by natural killer cells

artículo científico publicado en 1987

Molecular Approaches to the Role of the Microbiota in Inflammatory Bowel Disease

artículo científico publicado en 2006

Molecular cloning of a Bacteroides caccae TonB-linked outer membrane protein identified by an inflammatory bowel disease marker antibody

artículo científico publicado en 2001

Molecular imaging of murine intestinal inflammation with 2-deoxy-2-[18F]fluoro-D-glucose and positron emission tomography.

artículo científico publicado en 2008

Molecular patterns in human ulcerative colitis and correlation with response to infliximab

artículo científico publicado en 2014

Morbidity of subtotal colectomy in patients with severe ulcerative colitis unresponsive to cyclosporin

artículo científico publicado en 1995

Multidimensional prognostic risk assessment identifies association between IL12B variation and surgery in Crohn's disease

artículo científico publicado en 2013

Multiparameter analysis of immunogenetic mechanisms in clinical diagnosis and management of inflammatory bowel disease

artículo científico publicado en 2006

Multiple activating and repressive cis-promoter regions regulate TNFSF15 expression in human primary mononuclear cells

scientific article published on 30 April 2013

Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease

artículo científico publicado en 2002

Myeloid ATG16L1 Facilitates Host-Bacteria Interactions in Maintaining Intestinal Homeostasis.

artículo científico publicado en 2017

NK and T cell subsets regulate antibody production by human in vivo antigen-induced lymphoblastoid B cells ⬇️

artículo científico publicado el 1 de febrero de 1984

NOD2 variants and antibody response to microbial antigens in Crohn's disease patients and their unaffected relatives.

artículo científico publicado en 2006

Natalizumab Induction and Maintenance Therapy for Crohn's Disease

artículo científico publicado en 2005

Natalizumab for the treatment of active Crohn's disease: results of the ENCORE Trial

artículo científico publicado en 2007

Neutrophil autoantibodies as disease markers for ulcerative colitis

artículo científico publicado en 1991

Neutrophil autoantibodies in ulcerative colitis: Familial aggregation and genetic heterogeneity ⬇️

artículo científico publicado el 1 de agosto de 1992

Neutrophil cytoplasmic antibodies: a link between primary sclerosing cholangitis and ulcerative colitis

artículo científico publicado en 1991

New enema treatments for inflammatory bowel disease

artículo científico publicado en 1988

Nonbloody Diarrhea but Not Significant Weight Loss at Diagnosis Is Associated with the Development of Denovo Crohn's Disease After Ileal Pouch-anal Anastomosis for Ulcerative Colitis

artículo científico publicado en 2015

O-001 A Multicenter, Double-Blind, Placebo-Controlled Phase3 Study of Ustekinumab, a Human IL-12/23P40 mAB, in Moderate-Service Crohnʼs Disease Refractory to Anti-TFNα

OC-005 A Multicenter, Double-Blind, Placebo (PBO)-Controlled Ph3 Study of Ustekinumab (UST), A Human IL-12/23P40 MAB, in Moderate-Severe Crohn’s Disease (CD) Refractory to anti-TNFΑ: UNITI-1

Ocular Manifestations in Inflammatory Bowel Disease Are Associated with Other Extra-intestinal Manifestations, Gender, and Genes Implicated in Other Immune-related Traits.

artículo científico publicado en 2015

Oral mesalamine (Asacol) for mildly to moderately active ulcerative colitis. A multicenter study.

artículo científico publicado en 1991

Outcome of cytomegalovirus infections in patients with inflammatory bowel disease

artículo científico publicado en 2001

Outcomes with Anti-Tumour Necrosis Factor-Alpha Therapy and Serology in Patients with Denovo Crohn's Disease After Ileal Pouch Anal Anastomosis

artículo científico publicado en 2016

Patients with inflammatory bowel disease are at risk for vaccine-preventable illnesses.

artículo científico publicado en 2006

Pattern recognition receptor and autophagy gene variants are associated with development of antimicrobial antibodies in Crohn's disease

artículo científico publicado en 2012

Perianal Crohn's Disease is Associated with Distal Colonic Disease, Stricturing Disease Behavior, IBD-Associated Serologies and Genetic Variation in the JAK-STAT Pathway

artículo científico publicado en 2016

Perinuclear anti-neutrophil cytoplasmic antibodies are spontaneously produced by mucosal B cells of ulcerative colitis patients

scientific article published on 01 September 1995

Perinuclear antineutrophil cytoplasmic antibodies in patients with Crohn's disease define a clinical subgroup

artículo científico publicado en 1996

Phage display cloning and characterization of an immunogenetic marker (perinuclear anti-neutrophil cytoplasmic antibody) in ulcerative colitis

artículo científico publicado en 1996

Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease

artículo científico publicado en 2000

Phenotype and effector function of CC chemokine receptor 9-expressing lymphocytes in small intestinal Crohn's disease.

artículo científico publicado en 2007

Plasma N-Glycan Signatures Are Associated With Features of Inflammatory Bowel Diseases

artículo científico publicado en 2018

Potent inhibition of cytokine production from intestinal lamina propria T cells by phosphodiesterase-4 inhibitory thalidomide analogues

artículo científico publicado en 2001

Potential role for TL1A, the new TNF-family member and potent costimulator of IFN-gamma, in mucosal inflammation

artículo científico publicado en 2004

Pouchitis disease course after orthotopic liver transplantation in patients with primary sclerosing cholangitis and an ileal pouch-anal anastomosis

artículo científico publicado en 1995

Pre-Pouch Ileitis is Associated with Development of Crohn's Disease-Like Complications and Pouch Failure

artículo científico publicado en 2020

Predicting a change in diagnosis from ulcerative colitis to Crohn's disease: a nested, case-control study

artículo científico publicado en 2007

Preoperative wireless capsule endoscopy does not predict outcome after ileal pouch-anal anastomosis

artículo científico publicado en 2010

Prevalence and Associations of Avascular Necrosis of the Hip in a Large Well-characterized Cohort of Patients With Inflammatory Bowel Disease

artículo científico publicado en 2019

Prospective randomized open-label multicenter phase I/II dose escalation trial of visilizumab (HuM291) in severe steroid-refractory ulcerative colitis

artículo científico publicado en 2010

Pyoderma Gangrenosum among Patients with Inflammatory Bowel Disease: A Descriptive Cohort Study

artículo científico publicado en 2015

Randomised clinical trial: herbal extract HMPL-004 in active ulcerative colitis - a double-blind comparison with sustained release mesalazine

scientific article published on 30 November 2010

Recent advances in IBD pathogenesis: genetics and immunobiology

artículo científico publicado en 2008

Recent understanding of IBD pathogenesis: implications for future therapies

artículo científico publicado en 2006

Reduced expression of COVID-19 host receptor, ACE2 is associated with small bowel inflammation, more severe disease, and response to anti-TNF therapy in Crohn′s disease

artículo científico publicado en 2020

Relative Preservation of Treg Function in Tl1A-TG Mice Under Germ-Free Condition

Reliable generation of induced pluripotent stem cells from human lymphoblastoid cell lines

artículo científico publicado en 2014

Rigorous histopathological assessment of the colectomy specimen in patients with inflammatory bowel disease unclassified does not predict outcome after ileal pouch-anal anastomosis

artículo científico publicado en 2009

Role of antineutrophil cytoplasmic antibodies in an ethnically distinct population: Korean patients with ulcerative colitis.

artículo científico publicado en 1995

Role of the CD45 (T-200) molecule in anti-CD3-triggered T cell-mediated cytotoxicity

artículo científico publicado en 1988

SUSTAINED TL1A (TNFSF15) EXPRESSION ON BOTH LYMPHOID AND MYELOID CELLS LEADS TO MILD SPONTANEOUS INTESTINAL INFLAMMATION AND FIBROSIS.

artículo científico publicado en 2013

Safety and efficacy of adalimumab (D2E7) in Crohn's disease patients with an attenuated response to infliximab

artículo científico publicado en 2005

Segregation of pANCA antigenic recognition by DNase treatment of neutrophils: ulcerative colitis, type 1 autoimmune hepatitis, and primary sclerosing cholangitis

artículo científico publicado en 1995

Selected loss of tolerance evidenced by Crohn's disease-associated immune responses to auto- and microbial antigens

artículo científico publicado en 2002

Sero-reactivity to microbial components in Crohn's disease is associated with disease severity and progression, but not NOD2/CARD15 genotype

artículo científico publicado en 2004

Serologic responses in indeterminate colitis patients before ileal pouch-anal anastomosis may determine those at risk for continuous pouch inflammation

artículo científico publicado en 2005

Serologic, Genetic, and Clinical Associations with Increased Healthcare Resource Utilization in Inflammatory Bowel Disease.

artículo científico publicado en 2017

Serum immune responses predict rapid disease progression among children with Crohn's disease: immune responses predict disease progression

artículo científico publicado en 2006

Split-dose administration of thiopurine drugs: a novel and effective strategy for managing preferential 6-MMP metabolism

artículo científico

State of the art: IBD therapy and clinical trials in IBD.

artículo científico publicado en 2005

Studies on the mechanism of the human natural killer cell lethal hit: a new method for rapid physical isolation of lethally hit K562 targets and inhibition of cytolysis by reduced temperature or trypsin

artículo científico publicado en 1984

Substance P induces CCN1 expression via histone deacetylase activity in human colonic epithelial cells

artículo científico publicado en 2011

Sulfasalazine and salicylate-induced exacerbation of ulcerative colitis

artículo científico publicado en 1987

Sulfasalazine-Induced Exacerbation of Ulcerative Colitis ⬇️

artículo científico publicado el 18 de febrero de 1982

Surgical outcome of ileal pouch-anal anastomosis when used intentionally for well-defined Crohn's disease

artículo científico publicado en 2013

Susceptibility locus for inflammatory bowel disease on chromosome 16 has a role in Crohn's disease, but not in ulcerative colitis

artículo científico publicado en 1996

TL1A (TNFSF15) regulates the development of chronic colitis by modulating both T-helper 1 and T-helper 17 activation.

artículo científico publicado en 2008

TL1A blocking ameliorates intestinal fibrosis in the T cell transfer model of chronic colitis in mice

artículo científico publicado en 2017

TL1A selectively enhances IL-12/IL-18-induced NK cell cytotoxicity against NK-resistant tumor targets

artículo científico publicado en 2010

TL1A synergizes with IL-12 and IL-18 to enhance IFN-gamma production in human T cells and NK cells

artículo científico publicado en 2004

TLR8-mediated activation of human monocytes inhibits TL1A expression

artículo científico publicado en 2009

TNFRSF1B Is Associated with ANCA in IBD.

artículo científico publicado en 2016

TNFSF15 is an ethnic-specific IBD gene

artículo científico publicado en 2007

The "lazy" NK cells of Chediak-Higashi syndrome.

artículo científico publicado en 1983

The CD8+ Leu-7+ subset of T cells in Crohn's disease: distinction between cytotoxic and covert suppressor functions

artículo científico publicado en 1990

The Effects of Ustekinumab on Health-related Quality of Life in Patients With Moderate to Severe Crohn's Disease

artículo científico publicado en 2018

The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organization: when to start, when to stop, which drug to choose, and how to predict response?

artículo científico publicado en 2010

The T cell costimulator TL1A is induced by FcgammaR signaling in human monocytes and dendritic cells

artículo científico publicado en 2007

The TNF family member TL1A induces IL-22 secretion in committed human Th17 cells via IL-9 induction

artículo científico publicado en 2016

The antimicrobial peptide cathelicidin modulates Clostridium difficile-associated colitis and toxin A-mediated enteritis in mice.

artículo científico publicado en 2012

The effect of 6-mercaptopurine on natural killer-cell activities in Crohn's disease

artículo científico publicado en 1985

The impact of preoperative serum anti-TNFα therapy levels on early postoperative outcomes in inflammatory bowel disease surgery

artículo científico publicado en 2015

The presence of anti-neutrophil antibodies reflects clinical and genetic heterogeneity within inflammatory bowel disease

scientific article published on 01 February 1998

The spectrum of gastrointestinal toxicity and effect on disease activity of selective cyclooxygenase-2 inhibitors in patients with inflammatory bowel disease.

artículo científico publicado en 2004

Thioguanine: a potential alternate thiopurine for IBD patients allergic to 6-mercaptopurine or azathioprine

artículo científico publicado en 2003

Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology

artículo científico publicado en 2005

Transient cytokine-induced liver injury following administration of the humanized anti-CD3 antibody visilizumab (HuM291) in Crohn's disease

artículo científico publicado en 2009

Treatment With Infliximab Is Associated With Increased Markers of Bone Formation in Patients With Crohn??s Disease

scientific article published on 01 January 2006

Triggered human mucosal T cells release tumour necrosis factor-alpha and interferon-gamma which kill human colonic epithelial cells

artículo científico publicado en 1991

Tumor necrosis factor microsatellites define a Crohn's disease-associated haplotype on chromosome 6.

artículo científico publicado en 1996

Ulcerative colitis and total alopecia in a mother and her son

artículo científico publicado en 1993

Ulcerative colitis-linked antineutrophil cytoplasmic antibody in the cotton-top tamarin model of colitis

artículo científico publicado en 1992

Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study

artículo científico publicado en 2009

Ulcerative colitis: a genetically heterogeneous disorder defined by genetic (HLA class II) and subclinical (antineutrophil cytoplasmic antibodies) markers

artículo científico publicado en 1993

Use of animal models in elucidating disease pathogenesis in IBD.

artículo científico publicado en 2014

Ustekinumab as Induction and Maintenance Therapy for Crohn’s Disease

artículo científico publicado en 2016

Ustekinumab as Induction and Maintenance Therapy for Ulcerative Colitis

artículo científico publicado en 2019

Ustekinumab induction and maintenance therapy in refractory Crohn's disease

artículo científico publicado en 2012

Ustekinumab is effective and safe for ulcerative colitis through 2 years of maintenance therapy

artículo científico publicado en 2020

Variants in ZNF365 isoform D are associated with Crohn's disease ⬇️

artículo científico publicado el 21 de enero de 2011

Weeding out the facts: the reality about cannabis and Crohn's disease

artículo científico publicado en 2013

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