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Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation.

artículo científico publicado en 2015

Amyloid-β induced toxicity involves ganglioside expression and is sensitive to GM1 neuroprotective action.

artículo científico publicado en 2011

Beta-amyloid peptide toxicity in organotypic hippocampal slice culture involves Akt/PKB, GSK-3beta, and PTEN.

artículo científico publicado en 2006

Brain-Defective Insulin Signaling Is Associated to Late Cognitive Impairment in Post-Septic Mice.

artículo científico publicado en 2016

Challenges for Alzheimer's Disease Therapy: Insights from Novel Mechanisms Beyond Memory Defects

artículo científico publicado en 2018

Characterization of trans-resveratrol-loaded lipid-core nanocapsules and tissue distribution studies in rats

artículo científico publicado en 2010

Chronic stress and lithium treatments alter hippocampal glutamate uptake and release in the rat and potentiate necrotic cellular death after oxygen and glucose deprivation

artículo científico publicado en 2011

Estradiol protects against oxygen and glucose deprivation in rat hippocampal organotypic cultures and activates Akt and inactivates GSK-3beta.

artículo científico publicado en 2005

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models

artículo científico publicado en 2019

Free and nanoencapsulated curcumin suppress β-amyloid-induced cognitive impairments in rats: involvement of BDNF and Akt/GSK-3β signaling pathway

artículo científico publicado en 2013

Indomethacin-loaded lipid-core nanocapsules reduce the damage triggered by Aβ1-42 in Alzheimer's disease models.

artículo científico publicado en 2012

Lipid-core nanocapsules improve the effects of resveratrol against Abeta-induced neuroinflammation.

artículo científico publicado en 2013

Metabolic Dysfunction in Alzheimer's Disease: From Basic Neurobiology to Clinical Approaches

artículo científico publicado en 2018

Monoolein-based nanoparticles for drug delivery to the central nervous system: A platform for Lysosomal Storage Disorder treatment

article

Nanoparticles containing β-cyclodextrin potentially useful for the treatment of Niemann-Pick C

artículo científico publicado en 2020

Neuroprotection and protein damage prevention by estradiol replacement in rat hippocampal slices exposed to oxygen-glucose deprivation

artículo científico publicado en 2005

Neuroprotective effects of resveratrol against Aβ administration in rats are improved by lipid-core nanocapsules

artículo científico publicado en 2013

Protective effect of resveratrol against oxygen-glucose deprivation in organotypic hippocampal slice cultures: Involvement of PI3-K pathway

artículo científico publicado en 2006

Protective effects of indomethacin-loaded nanocapsules against oxygen-glucose deprivation in organotypic hippocampal slice cultures: involvement of neuroinflammation.

artículo científico publicado en 2010

Protective profile of oxcarbazepine against oxygen-glucose deprivation in organotypic hippocampal slice culture could involve PI3K cell signaling pathway.

artículo científico publicado en 2009

Resveratrol-loaded lipid-core nanocapsules treatment reduces in vitro and in vivo glioma growth.

artículo científico publicado en 2013

Selective cytotoxicity of indomethacin and indomethacin ethyl ester-loaded nanocapsules against glioma cell lines: an in vitro study

artículo científico publicado en 2008

TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's β-amyloid oligomers in mice and monkeys.

artículo científico publicado en 2013

The antiproliferative effect of indomethacin-loaded lipid-core nanocapsules in glioma cells is mediated by cell cycle regulation, differentiation, and the inhibition of survival pathways

artículo científico publicado en 2013

The curry spice curcumin attenuates beta-amyloid-induced toxicity through beta-catenin and PI3K signaling in rat organotypic hippocampal slice culture

artículo científico publicado el 14 de mayo de 2013

The effects of estradiol on estrogen receptor and glutamate transporter expression in organotypic hippocampal cultures exposed to oxygen--glucose deprivation

artículo científico publicado en 2006