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Lista de obras de Jaspal S Kooner

52 Genetic Loci Influencing Myocardial Mass

artículo científico publicado en 2016

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

artículo científico publicado en 2018

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

artículo científico publicado en 2017

A Replication Study of GWAS-Derived Lipid Genes in Asian Indians: The Chromosomal Region 11q23.3 Harbors Loci Contributing to Triglycerides ⬇️

artículo científico publicado el 18 de mayo de 2012

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies

artículo científico publicado en 2015

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

artículo científico publicado en 2015

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

artículo científico publicado en 2016

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

artículo científico publicado en 2016

Alcohol consumption is associated with widespread changes in blood DNA methylation: Analysis of cross-sectional and longitudinal data

artículo científico publicado en 2019

Analysis with the exome array identifies multiple new independent variants in lipid loci

artículo científico publicado en 2016

Association analyses based on false discovery rate implicate new loci for coronary artery disease ⬇️

artículo científico

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Associations of genetic variants in/near body mass index-associated genes with type 2 diabetes: a systematic meta-analysis

artículo científico publicado en 2014

Attenuated systemic microvascular function in men with coronary artery disease is associated with angina but not explained by atherosclerosis.

artículo científico publicado en 2013

Attenuation of microvascular function in those with cardiovascular disease is similar in patients of Indian Asian and European descent

artículo científico publicado en 2010

Author Correction: Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps

artículo científico publicado en 2018

Bio-Repository of DNA in stroke (BRAINS): a study protocol

artículo científico publicado en 2011

Biological, clinical and population relevance of 95 loci for blood lipids

artículo científico publicado en 2010

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

artículo científico publicado en 2017

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease

artículo científico publicado en 2013

Common genetic variation near MC4R is associated with waist circumference and insulin resistance

artículo científico publicado en 2008

Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians

artículo científico publicado en 2009

Common variants associated with plasma triglycerides and risk for coronary artery disease

artículo científico publicado en 2013

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

artículo científico publicado en 2010

Common variants at 30 loci contribute to polygenic dyslipidemia

artículo científico publicado en 2009

Comparing methods for performing trans-ethnic meta-analysis of genome-wide association studies

artículo científico publicado en 2013

Contrast-enhanced ultrasonography vs B-mode ultrasound for visualization of intima-media thickness and detection of plaques in human carotid arteries

artículo científico publicado en 2017

Contribution of lower physical activity levels to higher risk of insulin resistance and associated metabolic disturbances in South Asians compared to Europeans

article

Coronary heart disease in Indian Asians

artículo científico publicado en 2014

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

artículo científico publicado en 2009

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

artículo científico publicado en 2017

DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

artículo científico publicado en 2021

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Diabetes, insulin resistance and vascular disease among Indian Asians and Europeans

artículo científico publicado en 2002

Directional dominance on stature and cognition in diverse human populations

artículo científico publicado en 2015

Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps

artículo científico publicado en 2016

Discovery and refinement of loci associated with lipid levels

artículo científico publicado en 2013

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

artículo científico publicado en 2020

Disentangling the genetics of lean mass

article

Does subclinical atherosclerosis burden identify the increased risk of cardiovascular disease mortality among United Kingdom Indian Asians? A population study ⬇️

artículo científico publicado el 9 de agosto de 2011

Elevated Levels of Organochlorine Pesticides in South Asian Immigrants Are Associated With an Increased Risk of Diabetes

article

Epigenetic Link Between Statin Therapy and Type 2 Diabetes

scientific article published on 07 February 2020

Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study

scientific article published on 10 September 2019

Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study

artículo científico publicado en 2015

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

artículo científico publicado en 2016

Erratum to: A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies.

artículo científico publicado en 2016

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

artículo científico publicado en 2017

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2018

Estimation of central aortic pressure by SphygmoCor requires intra-arterial peripheral pressures

scientific article published on 01 August 2003

Ethnic and gender differences in the relationship between hostility and metabolic and autonomic risk factors for coronary heart disease.

artículo científico publicado en 2010

Ethnicity differences in genetic susceptibility to ulcerative colitis: a comparison of Indian asians and white northern Europeans

artículo científico publicado en 2013

Ethnicity-related differences in left ventricular function, structure and geometry: a population study of UK Indian Asian and European white subjects

artículo científico publicado en 2009

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

article by Jason Flannick et al published 22 May 2019 in Nature

Exome-wide association study of plasma lipids in >300,000 individuals

artículo científico publicado en 2017

Fine-scale estimation of location of birth from genome-wide single-nucleotide polymorphism data

artículo científico publicado en 2011

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease

artículo científico publicado en 2009

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes

artículo científico publicado en 2014

Genetic loci influencing kidney function and chronic kidney disease

artículo científico publicado en 2010

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

artículo científico publicado en 2011

Genetic variants influencing circulating lipid levels and risk of coronary artery disease

artículo científico publicado en 2010

Genetic variation in SCN10A influences cardiac conduction

artículo científico publicado en 2010

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

artículo científico publicado en 2011

Genetically determined height and coronary artery disease

artículo científico publicado en 2015

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

artículo científico publicado en 2018

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

artículo científico publicado en 2013

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

artículo científico publicado en 2017

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

scientific journal article

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

artículo científico publicado en 2011

Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels ⬇️

artículo científico publicado en 2016

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

artículo científico publicado en 2009

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

artículo científico publicado en 2012

Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India

artículo científico publicado en 2013

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

artículo científico publicado en 2011

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

artículo científico publicado en 2011

Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels

artículo científico publicado en 2009

Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

artículo científico publicado en 2011

Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene

artículo científico publicado en 2010

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

artículo científico publicado en 2017

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides

artículo científico publicado en 2008

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

artículo científico publicado en 2014

Guidelines in cardiac clinical practice: evaluation of their methodological quality using the AGREE II instrument.

artículo científico publicado en 2013

Heparin-induced thrombocytopenia (HIT) as an unusual cause of acute stent thrombosis

artículo científico publicado en 2009

Homocysteine and Coronary Heart Disease: Meta-analysis of MTHFR Case-Control Studies, Avoiding Publication Bias ⬇️

artículo científico publicado el 21 de febrero de 2012

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

artículo científico publicado en 2017

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

artículo científico publicado en 2017

Indian Asian men have less peripheral arterial disease than European men for equivalent levels of coronary disease

article

Interethnic analyses of blood pressure loci in populations of East Asian and European descent

artículo científico publicado en 2018

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

artículo científico publicado en 2012

Investigation of Genetic Variation Underlying Central Obesity amongst South Asians

artículo científico publicado en 2016

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

artículo científico publicado en 2016

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

artículo científico publicado en 2017

Large-scale association analysis identifies new risk loci for coronary artery disease

artículo científico publicado en 2012

Localisation of SCN10A gene product Na(v)1.8 and novel pain-related ion channels in human heart

artículo científico publicado en 2011

Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions

artículo científico publicado en 2017

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

artículo científico publicado en 2014

Management of Acute Coronary Syndromes During the Coronavirus Disease 2019 Pandemic: Deviations from Guidelines and Pragmatic Considerations for Patients and Healthcare Workers

scientific article published on 01 April 2020

Measurement of pulse wave velocity: site matters

artículo científico publicado en 2007

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

artículo científico publicado en 2010

Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations

artículo científico publicado en 2012

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

artículo científico publicado en 2016

Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations

artículo científico publicado en 2013

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

artículo científico publicado en 2019

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

article

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

artículo científico publicado en 2018

Multidetector computed tomography of a giant left mainstem aneurysm ⬇️

artículo científico publicado el 12 de octubre de 2011

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

artículo científico publicado en 2013

Myocardial beta-adrenoceptor density one month after acute myocardial infarction predicts left ventricular volumes at six months.

artículo científico publicado en 2002

Myocardial beta-adrenoceptor down-regulation early after infarction is associated with long-term incidence of congestive heart failure

artículo científico publicado en 2010

NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality

artículo científico

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

artículo científico publicado en 2017

New gene functions in megakaryopoiesis and platelet formation

artículo científico publicado en 2011

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

New insights into the relationship of left ventricular geometry and left ventricular mass with cardiac function: A population study of hypertensive subjects

scientific article published on 19 November 2009

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

artículo científico publicado en 2016

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis ⬇️

scientific article published on 12 October 2016

Normal value of carotid intima-media thickness--a surrogate marker of atherosclerosis: quantitative assessment by B-mode carotid ultrasound

artículo científico publicado en 2007

Normative reference values for the tissue Doppler imaging parameters of left ventricular function: a population-based study

artículo científico publicado en 2009

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

artículo científico publicado en 2017

Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index

artículo científico publicado en 2014

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

artículo científico publicado en 2018

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Polymorphisms in the WNK1 gene are associated with blood pressure variation and urinary potassium excretion

artículo científico publicado en 2009

Population-Based Reference Values for 3D Echocardiographic LV Volumes and Ejection Fraction ⬇️

artículo científico publicado el 1 de diciembre de 2012

Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes

artículo científico publicado en 2008

Prevalence of coronary artery calcium scores and silent myocardial ischaemia was similar in Indian Asians and European whites in a cross-sectional study of asymptomatic subjects from a UK population (LOLIPOP-IPC) ⬇️

artículo científico publicado el 9 de abril de 2011

Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics

article

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Psychosocial factors related to cardiovascular disease risk in UK South Asian men: a preliminary study.

artículo científico publicado en 2007

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

artículo científico publicado en 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

artículo científico publicado en 2018

SLC2A9 is a high-capacity urate transporter in humans

artículo científico publicado en 2008

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2017

Serum metabolic signatures of coronary and carotid atherosclerosis and subsequent cardiovascular disease

artículo científico publicado en 2019

Seventy-five genetic loci influencing the human red blood cell

artículo científico publicado en 2012

South Asian men have different patterns of coronary artery disease when compared with European men.

artículo científico publicado en 2007

South Asians have adverse cerebrovascular haemodynamics, despite equivalent blood pressure, compared with Europeans. This is due to their greater hyperglycaemia

artículo científico publicado en 2011

South Asians have elevated postexercise blood pressure and myocardial oxygen consumption compared to Europeans despite equivalent resting pressure

artículo científico publicado en 2012

Subgroup differences in psychosocial factors relating to coronary heart disease in the UK South Asian population

artículo científico publicado en 2010

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

artículo científico publicado en 2019

The CXCL16 A181V Mutation Selectively Inhibits Monocyte Adhesion to CXCR6 but Is Not Associated With Human Coronary Heart Disease ⬇️

artículo científico publicado el 13 de enero de 2011

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research

artículo científico publicado en 2008

The South Asian genome.

artículo científico publicado en 2014

The distinct relationships of carotid plaque disease and carotid intima-media thickness with left ventricular function

artículo científico publicado en 2010

The genetic architecture of type 2 diabetes

artículo científico publicado en 2016

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

Training a model for estimating leukocyte composition using whole-blood DNA methylation and cell counts as reference.

artículo científico publicado en 2016

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

artículo científico publicado en 2015

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms

artículo científico publicado en 2016

Transcriptional diversity during lineage commitment of human blood progenitors

artículo científico publicado en 2014

Tubercular myocarditis presenting with ventricular tachycardia.

artículo científico publicado en 2008

Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits

artículo científico publicado en 2017

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