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3D-biohybrid systems: applications in drug screening

scientific article published on 01 February 2002

A Novel 3D Label-Free Monitoring System of hES-Derived Cardiomyocyte Clusters: A Step Forward to In Vitro Cardiotoxicity Testing

artículo científico publicado el 8 de julio de 2013

A cell-based impedance assay for monitoring transient receptor potential (TRP) ion channel activity

artículo científico publicado en 2010

A microelectrode-based sensor for label-free in vitro detection of ischemic effects on cardiomyocytes

artículo científico publicado en 2009

A multidimensional impedance platform for the real-time analysis of single and combination drug pharmacology in patient-derived viable melanoma models

artículo científico publicado en 2018

A novel 384-multiwell microelectrode array for the impedimetric monitoring of Tau protein induced neurodegenerative processes

artículo científico publicado en 2016

A novel 96-well multielectrode array based impedimetric monitoring platform for comparative drug efficacy analysis on 2D and 3D brain tumor cultures

artículo científico publicado en 2014

A novel microfluidic microelectrode chip for a significantly enhanced monitoring of NPY-receptor activation in live mode

artículo científico publicado en 2017

A novel organotypic tauopathy model on a new microcavity chip for bioelectronic label-free and real time monitoring

artículo científico publicado en 2010

Age-related gene expression analysis in enteric ganglia of human colon after laser microdissection

artículo científico publicado en 2014

An electrode array for electrochemical immuno-sensing using the example of impedimetric tenascin C detection

artículo científico publicado el 13 de julio de 2011

An impedimetric microelectrode-based array sensor for label-free detection of tau hyperphosphorylation in human cells

artículo científico publicado en 2009

Biosensing and drug delivery at the microscale : novel devices for controlled and responsive drug delivery

scientific article published on January 2010

Cells on a chip--the use of electric properties for highly sensitive monitoring of blood-derived factors involved in angiotensin II type 1 receptor signalling

artículo científico publicado en 2005

Comparative label-free monitoring of immunotoxin efficacy in 2D and 3D mamma carcinoma in vitro models by impedance spectroscopy

artículo científico publicado en 2013

Comprehensive human stem cell differentiation in a 2D and 3D mode to cardiomyocytes for long-term cultivation and multiparametric monitoring on a multimodal microelectrode array setup

scientific article published on 29 October 2018

Continuous purification of reaction products by micro free-flow electrophoresis enabled by large area deep-UV fluorescence imaging.

artículo científico publicado en 2017

Correction: The anti-tumorigenic activity of A2M-A lesson from the naked mole-rat

artículo científico publicado en 2018

Crystallization of ectonucleotide phosphodiesterase/pyrophosphatase-3 and orientation of the SMB domains in the full-length ectodomain

artículo científico publicado en 2018

Cytomics and nanobioengineering.

artículo científico publicado en 2008

DIGE Proteome Analysis Reveals Suitability of Ischemic Cardiac In Vitro Model for Studying Cellular Response to Acute Ischemia and Regeneration

artículo científico publicado el 22 de febrero de 2012

Direct chemosensitivity monitoring ex vivo on undissociated melanoma tumor tissue by impedance spectroscopy

artículo científico publicado en 2014

Drug testing on 3D in vitro tissues trapped on a microcavity chip

artículo científico publicado en 2008

Electrochemical live monitoring of tumor cell migration out of micro-tumors on an innovative multiwell high-dense microelectrode array

scientific article published on 25 September 2019

Exogenous application of persephin influences phosphatidylinositol-3 kinase and MAPK/ERK signalling and enhances proliferation during early development in retinospheres

artículo científico publicado en 2008

FEM-based design of optical transparent indium tin oxide multielectrode arrays for multiparametric, high sensitive cell based assays

artículo científico publicado en 2018

First report on the effect of thrombin and factor Xa on cardiomyocytes in a three-dimensional cell culture model

scientific article published on 30 December 2008

Generation of carrier peptides for the delivery of nucleic acid drugs in primary cells

artículo científico publicado en 2008

Immunocytochemical analysis of glycogen phosphorylase isozymes in the developing and adult retina of the domestic chicken (Gallus domesticus).

artículo científico publicado en 2007

Impedance spectroscopy based measurement system for quantitative and label-free real-time monitoring of tauopathy in hippocampal slice cultures

artículo científico publicado el 23 de diciembre de 2011

Impedance spectroscopy—An outstanding method for label-free and real-time discrimination between brain and tumor tissue in vivo

artículo científico publicado el 16 de febrero de 2013

Impedimetric real-time monitoring of neural pluripotent stem cell differentiation process on microelectrode arrays

artículo científico publicado en 2016

In vitro field potential monitoring on a multi-microelectrode array for the electrophysiological long-term screening of neural stem cell maturation.

artículo científico publicado en 2017

In vivo intravascular electric impedance spectroscopy using a new catheter with integrated microelectrodes

artículo científico publicado en 2004

Induced Tauopathy in a Novel 3D-Culture Model Mediates Neurodegenerative Processes: A Real-Time Study on Biochips

artículo científico publicado el 7 de noviembre de 2012

Induced cross-resistance of BRAF melanoma cells to standard chemotherapeutic dacarbazine after chronic PLX4032 treatment

artículo científico publicado en 2019

Knock-down of GFRalpha4 expression by RNA interference affects the development of retinal cell types in three-dimensional histiotypic retinal spheres

artículo científico publicado en 2006

Microcavity array (MCA)-based biosensor chip for functional drug screening of 3D tissue models

artículo científico publicado en 2008

Microelectrode chip based real time monitoring of vital MCF-7 mamma carcinoma cells by impedance spectroscopy

artículo científico publicado en 2008

Neurturin, a member of the glial cell line-derived neurotrophic factor family, affects the development of acetylcholinesterase-positive cells in a three-dimensional model system of retinogenesis

artículo científico publicado en 2008

New insights into the biology of preeclampsia

artículo científico publicado en 2006

Novel 96-well quantitative bioelectrocatalytic analysis platform reveals highly efficient direct electrode regeneration of cytochrome P450 BM3 on indium tin oxide

artículo científico publicado en 2016

Of layers and spheres: the reaggregate approach in tissue engineering

artículo científico publicado en 2002

Peptide-Mediated Specific Immobilization of Catalytically Active Cytochrome P450 BM3 Variant

artículo científico publicado en 2016

Quantitative characterization of capsaicin-induced TRPV1 ion channel activation in HEK293 cells by impedance spectroscopy

artículo científico publicado en 2016

Quantitative impedimetric NPY-receptor activation monitoring and signal pathway profiling in living cells

artículo científico publicado en 2014

Real-time measurement of PMA-induced cellular alterations by microelectrode array-based impedance spectroscopy

artículo científico publicado en 2006

Real-time monitoring of relaxation and contractility of smooth muscle cells on a novel biohybrid chip

artículo científico publicado el 8 de septiembre de 2010

Spatial and temporal expression patterns of GDNF family receptor alpha4 in the developing chicken retina

artículo científico publicado en 2004

Spheroids of granulosa cells provide an in vitro model for programmed cell death coupled to steroidogenesis

artículo científico publicado en 2008

Synaptic transmission and short-term plasticity at the calyx of Held synapse revealed by multielectrode array recordings.

artículo científico publicado en 2008

The anti-tumorigenic activity of A2M-A lesson from the naked mole-rat

artículo científico publicado en 2017

The transcription factor Yin Yang 1 is an activator of BACE1 expression

scientific journal article