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Lista de obras de Peter Scheurich

A TNF receptor 2 selective agonist rescues human neurons from oxidative stress-induced cell death

artículo científico publicado en 2011

A humanized tumor necrosis factor receptor 1 (TNFR1)-specific antagonistic antibody for selective inhibition of tumor necrosis factor (TNF) action

artículo científico publicado en 2008

A maximum likelihood estimator for parameter distributions in heterogeneous cell populations

article by Jan Hasenauer et al published May 2010 in Procedia Computer Science

A permissive role for tumor necrosis factor in vascular endothelial growth factor-induced vascular permeability.

artículo científico publicado en 2001

A single-chain TNF receptor antagonist is an effective inhibitor of TNF mediated cytotoxicity.

artículo científico publicado en 1995

A visual analytics approach for models of heterogeneous cell populations

artículo científico publicado en 2012

ATROSAB, a humanized antagonistic anti-tumor necrosis factor receptor one-specific antibody

artículo científico publicado el 1 de noviembre de 2010

An anti-TNFR1 scFv-HSA fusion protein as selective antagonist of TNF action

artículo científico publicado el 4 de septiembre de 2013

Analysis of heterogeneous cell populations: A density-based modeling and identification framework

article

Analysis of interleukin 2 receptor sites on activated T cells

scientific article published on 01 May 1983

Analysis of lymphokine producing T helper cells at the clonal level

artículo científico publicado el 1 de mayo de 1983

Antagonistic TNF receptor one-specific antibody (ATROSAB): receptor binding and in vitro bioactivity

artículo científico publicado en 2013

Antagonistic control of tumor necrosis factor receptors by protein kinases A and C. Enhancement of TNF receptor synthesis by protein kinase A and transmodulation of receptors by protein kinase C.

artículo científico publicado en 1989

Antagonists of TNF action: clinical experience and new developments

artículo científico publicado el 1 de marzo de 2009

Apoptotic crosstalk of TNF receptors: TNF-R2-induces depletion of TRAF2 and IAP proteins and accelerates TNF-R1-dependent activation of caspase-8

artículo científico publicado en 2002

Bcl-2-mediated control of TRAIL-induced apoptotic response in the non-small lung cancer cell line NCI-H460 is effective at late caspase processing steps

artículo científico publicado en 2018

Biological effects of gamma-interferon on human tumor cells: quantity and affinity of cell membrane receptors for gamma-IFN in relation to growth inhibition and induction of HLA-DR expression

artículo científico publicado en 1985

Bistability analyses of a caspase activation model for receptor-induced apoptosis

artículo científico publicado en 2004

Both tumor necrosis factor receptors, TNFR60 and TNFR80, are involved in signaling endothelial tissue factor expression by juxtacrine tumor necrosis factor alpha

artículo científico publicado en 1995

Caspase-mediated cleavage converts the tumor necrosis factor (TNF) receptor-associated factor (TRAF)-1 from a selective modulator of TNF receptor signaling to a general inhibitor of NF-kappaB activation

artículo científico publicado en 2003

Cationic cell-penetrating peptides interfere with TNF signalling by induction of TNF receptor internalization

artículo científico publicado en 2005

Coexpression of the human TNF receptors TR60 and TR80 in insect cells: analysis of receptor complex formation

artículo científico publicado en 1994

Conference

artículo científico publicado en 1998

Continuous autotropic signaling by membrane-expressed tumor necrosis factor

artículo científico publicado en 1999

Control of receptor-induced signaling complex formation by the kinetics of ligand/receptor interaction

artículo científico publicado en 2002

Critical involvement of transmembrane tumor necrosis factor-alpha in endothelial programmed cell death mediated by ionizing radiation and bacterial endotoxin

artículo científico publicado en 1995

Death wins against life in a spatially extended model of the caspase-3/8 feedback loop

artículo científico publicado en 2012

Density-based modeling and identification of biochemical networks in cell populations

Development of resistance to tumour necrosis factor (TNF alpha) in KYM-1 cells involves both TNF receptors

artículo científico publicado en 1993

Differential activation of TRAIL-R1 and -2 by soluble and membrane TRAIL allows selective surface antigen-directed activation of TRAIL-R2 by a soluble TRAIL derivative

scientific article published on 01 July 2001

Differential gamma-interferon response of human colon carcinoma cells: inhibition of proliferation and modulation of immunogenicity as independent effects of gamma-interferon on tumor cell growth

scientific article published on 01 August 1985

Dissection of the proliferative and differentiative signals controlling murine cytotoxic T lymphocyte responses

artículo científico publicado en 1982

Dominant negative effects of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 4 on TRAIL receptor 1 signaling by formation of heteromeric complexes

artículo científico publicado en 2014

Dominant-negative FADD inhibits TNFR60-, Fas/Apo1- and TRAIL-R/Apo2-mediated cell death but not gene induction

artículo científico publicado en 1998

Downregulation of tumor necrosis factor (TNF) sensitivity via modulation of TNF binding capacity by protein kinase C activators

artículo científico publicado en 1987

Dual function of cysteine rich domain (CRD) 1 of TNF receptor type 1: conformational stabilization of CRD2 and control of receptor responsiveness

artículo científico publicado en 2010

Early events during primary activation of T cells: antigen receptor cross-linking and interleukin 1 initiate proliferative response of human T cells

artículo científico publicado en 1985

Endogenous membrane tumor necrosis factor (TNF) is a potent amplifier of TNF receptor 1-mediated apoptosis

artículo científico publicado en 2002

Enhanced MYCN oncogene expression in human neuroblastoma cells results in increased susceptibility to growth inhibition by TNF alpha

artículo científico publicado en 1990

Enhancement of TNF receptor p60-mediated cytotoxicity by TNF receptor p80: requirement of the TNF receptor-associated factor-2 binding site

scientific article published on 01 March 1997

Evidence that tumor necrosis factor alpha (TNF)-induced activation of neutrophil respiratory burst on biologic surfaces is mediated by the p55 TNF receptor

artículo científico publicado en 1994

Expression of complete human IFN-gamma receptor and its extracellular domain in insect cells: purification and characterization of the recombinant proteins.

artículo científico

Fas-associated death domain protein (FADD) and caspase-8 mediate up-regulation of c-Fos by Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) via a FLICE inhibitory protein (FLIP)-regulated pathway

artículo científico publicado en 2001

Fluorescence correlation spectroscopy reveals topological segregation of the two tumor necrosis factor membrane receptors

artículo científico publicado en 2010

Global Uncertainty Analysis for a Model of TNF-Induced NF-κB Signalling

Glycosylation of the human interferon-gamma receptor. N-linked carbohydrates contribute to structural heterogeneity and are required for ligand binding

artículo científico publicado en 1990

Heterogeneity reduces sensitivity of cell death for TNF-stimuli

artículo científico publicado en 2011

High affinity human IFN-gamma-binding capacity is encoded by a single receptor gene located in proximity to c-ros on human chromosome region 6q16 to 6q22

scientific article published on 01 August 1988

IFN-gamma receptors on human tumor cells: relationship between receptor ligand interactions and induction of IFN-gamma response

artículo científico publicado en 1986

Identification of a 60-kD tumor necrosis factor (TNF) receptor as the major signal transducing component in TNF responses

artículo científico publicado en 1990

Identification of a TRAF (TNF receptor-associated factor) gene in Caenorhabditis elegans

artículo científico publicado en 1998

Identification of models of heterogeneous cell populations from population snapshot data

artículo científico publicado en 2011

Immunoregulatory activity of recombinant human tumor necrosis factor (TNF)-alpha: induction of TNF receptors on human T cells and TNF-alpha-mediated enhancement of T cell responses

scientific article published on 01 March 1987

Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF.

artículo científico publicado en 1999

Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD)

artículo científico publicado en 2000

Intracellular localization and transcriptional regulation of tumor necrosis factor (TNF) receptor-associated factor 4 (TRAF4)

artículo científico publicado en 2002

Ligand-induced internalization of TNF receptor 2 mediated by a di-leucin motif is dispensable for activation of the NFκB pathway

artículo científico publicado en 2010

Ligands working as receptors: reverse signaling by members of the TNF superfamily enhance the plasticity of the immune system

artículo científico publicado en 2004

Mechanisms of TNF resistance: identification of membrane phosphoproteins associated with a dominant resistant phenotype in lymphoid-myeloid somatic cell hybrids

artículo científico publicado en 1988

Membrane tumor necrosis factor (TNF) induced cooperative signaling of TNFR60 and TNFR80 favors induction of cell death rather than virus production in HIV-infected T cells

artículo científico publicado en 1997

Molecular Cloning and Expression of Human and Rat Tumor Necrosis Factor Receptor Chain (p60) and Its Soluble Derivative, Tumor Necrosis Factor-Binding Protein

artículo científico publicado el 1 de diciembre de 1990

Monovalent TNF receptor 1-selective antibody with improved affinity and neutralizing activity

scientific article published on 02 October 2018

Murine T cell subsets and interleukins: relationships between cytotoxic T cells, helper T cells and accessory cells

artículo científico publicado el 1 de octubre de 1982

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling

artículo científico publicado en 2001

NFkappaB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP.

artículo científico publicado en 2004

Nanoscale arrangement of apoptotic ligands reveals a demand for a minimal lateral distance for efficient death receptor activation

artículo científico publicado en 2009

Nanotube Action between Human Mesothelial Cells Reveals Novel Aspects of Inflammatory Responses

artículo científico publicado el 27 de diciembre de 2011

Non-apoptotic Fas signaling.

artículo científico publicado en 2003

Noncytocidal mechanisms of action of tumor necrosis factor-alpha on human tumor cells: enhancement of HLA gene expression synergistic with interferon-gamma.

artículo científico publicado en 1986

ON/OFF and beyond--a boolean model of apoptosis

artículo científico publicado en 2009

Oncogenic stress induced by acute hyper-activation of Bcr-Abl leads to cell death upon induction of excessive aerobic glycolysis

artículo científico publicado en 2011

Organization of the human tumour necrosis factor receptor-associated factor 1 (TRAF1) gene and mapping to chromosome 9q33–34

artículo científico publicado el 11 de agosto de 1997

Postnatal development of functional T cell subsets in the mouse: a frequency analysis of mitogen reactive precursors of proliferating, of cytotoxic and of IL 2 producing T cells

artículo científico publicado en 1985

Quantification and characterization of high-affinity membrane receptors for tumor necrosis factor on human leukemic cell lines

scientific article published on 01 July 1986

Quantitation and characterization of gamma-interferon receptors on human tumor cells

artículo científico publicado en 1986

Quantitative representation of all T cells committed to develop into cytotoxic effector cells and/or interleukin 2 activity-producing helper cells within murine T lymphocyte subsets

artículo científico publicado el 1 de enero de 1984

Rapid modulation of tumor necrosis factor membrane receptors by activators of protein kinase C

artículo científico publicado en 1986

Response to bistability in apoptosis: roles of bax, bcl-2, and mitochondrial permeability transition pores

artículo científico publicado en 2007

Reverse signaling through transmembrane TNF confers resistance to lipopolysaccharide in human monocytes and macrophages

artículo científico publicado en 2000

Role of the 75-kDa TNF receptor in TNF-induced activation of neutrophil respiratory burst

artículo científico publicado en 1999

Segregation of APO‐1/Fas antigen‐ and tumor necrosis factor receptor‐mediated apoptosis

artículo científico publicado el 1 de octubre de 1994

Selective Blocking of TNF Receptor 1 Attenuates Peritoneal Dialysis Fluid Induced Inflammation of the Peritoneum in Mice

artículo científico publicado en 2016

Sensitivity analysis of programmed cell death and implications for crosstalk phenomena during Tumor Necrosis Factor stimulation

Sensitivity analysis of programmed cell death and implications for crosstalk phenomena during Tumor Necrosis Factor stimulation

Sequential therapy with recombinant interferons gamma and alpha in patients with unfavorable prognosis of chronic myelocytic leukemia: clinical responsiveness to recombinant IFN-alpha correlates with the degree of receptor down-regulation

artículo científico publicado en 1989

Single chain TNF derivatives with individually mutated receptor binding sites reveal differential stoichiometry of ligand receptor complex formation for TNFR1 and TNFR2

artículo científico publicado en 2010

Single-chain TNF, a TNF derivative with enhanced stability and antitumoral activity

artículo científico publicado en 2008

Specific membrane receptors for human interferon-gamma (IFN-gamma).

artículo científico publicado en 1987

Steady state and (bi-) stability evaluation of simple protease signalling networks

artículo científico publicado en 2007

Stress-induced TRAILR2 expression overcomes TRAIL resistance in cancer cell spheroids

scientific article published on 20 May 2020

Synergistic induction of endothelial tissue factor by tumor necrosis factor and vascular endothelial growth factor: functional analysis of the tumor necrosis factor receptors

artículo científico publicado en 1996

T-T cell interactions during in vitro cytotoxic T cell responses. VI. The role of T cell-derived colony-stimulating factor in helper T cell activation

artículo científico publicado en 1984

T-T cell interactions during in vitro cytotoxic T lymphocyte responses. V. Precursor frequencies and specificity of alloreactive helper T cells

artículo científico publicado el 1 de julio de 1982

TNF Signaling in Peritoneal Mesothelial Cells: Pivotal Role of cFLIPL.

artículo científico publicado en 2017

TNF receptor associated factors in cytokine signaling.

artículo científico publicado en 1999

TNF receptors TR60 and TR80 can mediate apoptosis via induction of distinct signal pathways

artículo científico publicado en 1994

TNF signal transduction and TNF-responsive genes

artículo científico publicado el 1 de enero de 1992

TNF-related apoptosis inducing ligand (TRAIL) and its receptors in tumor surveillance and cancer therapy

artículo científico publicado en 2002

TNFR1-induced activation of the classical NF-κB pathway

artículo científico publicado en 2011

TNFR80-dependent enhancement of TNFR60-induced cell death is mediated by TNFR-associated factor 2 and is specific for TNFR60

scientific article published on 01 September 1998

TR60 and TR80 tumor necrosis factor (TNF)-receptors can independently mediate cytolysis

artículo científico publicado en 1993

TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways

artículo científico publicado en 1998

TWEAK can induce cell death via endogenous TNF and TNF receptor 1.

artículo científico publicado en 1999

Targeted lipid-coated nanoparticles: delivery of tumor necrosis factor-functionalized particles to tumor cells

artículo científico publicado en 2009

The Met-196 -> Arg variation of human tumor necrosis factor receptor 2 (TNFR2) affects TNF-alpha-induced apoptosis by impaired NF-kappaB signaling and target gene expression

artículo científico publicado en 2004

The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators

artículo científico publicado en 2001

The Transmembrane Domains of TNF-Related Apoptosis-Inducing Ligand (TRAIL) Receptors 1 and 2 Co-Regulate Apoptotic Signaling Capacity

artículo científico publicado el 3 de agosto de 2012

The Tumor Necrosis Factor Receptor Stalk Regions Define Responsiveness to Soluble versus Membrane-Bound Ligand

artículo científico publicado el 30 de abril de 2012

The human tumor necrosis factor (TNF) receptor-associated factor 1 gene (TRAF1) is up-regulated by cytokines of the TNF ligand family and modulates TNF-induced activation of NF-kappaB and c-Jun N-terminal kinase

artículo científico publicado en 1999

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

scientific journal article

The tumor necrosis factor-related apoptosis-inducing ligand receptors TRAIL-R1 and TRAIL-R2 have distinct cross-linking requirements for initiation of apoptosis and are non-redundant in JNK activation

artículo científico publicado en 2000

The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor

artículo científico publicado el 20 de enero de 1998

Tumor necrosis factor (TNF) alpha: control of TNF-sensitivity and molecular mechanisms of TNF-mediated growth inhibition

artículo científico publicado en 1987

Tumor necrosis factor (TNF) and phorbol ester induce TNF-related apoptosis-inducing ligand (TRAIL) under critical involvement of NF-kappa B essential modulator (NEMO)/IKKgamma

artículo científico publicado en 2001

Tumor necrosis factor (TNF) receptor type 2 mediates thymocyte proliferation independently of TNF receptor type 1

artículo científico publicado en 1998

Tumor necrosis factor (TNF)-functionalized nanostructured particles for the stimulation of membrane TNF-specific cell responses

artículo científico publicado en 2005

Tumor necrosis factor and lymphotoxin gene expression in human tumor cell lines.

artículo científico publicado en 1988

Tumor necrosis factor enhances HLA-A,B,C and HLA-DR gene expression in human tumor cells

artículo científico publicado en 1987

Tumor necrosis factor receptor-associated factor (TRAF) 1 regulates CD40-induced TRAF2-mediated NF-kappaB activation

artículo científico publicado en 2003

Tumor necrosis factor receptor-associated factor (TRAF) 2 and its role in TNF signaling.

artículo científico publicado en 2001

Tumor necrosis factor receptor-associated factor-1 enhances proinflammatory TNF receptor-2 signaling and modifies TNFR1-TNFR2 cooperation

artículo científico publicado en 2009

Tumor necrosis factor signal transduction. Tissue-specific serine phosphorylation of a 26-kDa cytosolic protein.

artículo científico publicado en 1989

Tumor necrosis factor signaling.

artículo científico publicado en 2003

Tumor necrosis factor-induced changes of gene expression in U937 cells. Differentiation-dependent plasticity of the responsive state

artículo científico publicado en 1988

Tumor necrosis factor-receptor 2 is up-regulated on lamina propria T cells in Crohn's disease and promotes experimental colitis in vivo

artículo científico publicado en 2002

Tumour necrosis factor signal transduction

artículo científico publicado en 1990

p53 upregulates cFLIP, inhibits transcription of NF-kappaB-regulated genes and induces caspase-8-independent cell death in DLD-1 cells

artículo científico publicado en 2001