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A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression

scientific article published on 11 March 2009

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

artículo científico publicado en 2012

An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients

artículo científico publicado en 2013

Antiretroviral intensification and valproic acid lack sustained effect on residual HIV-1 viremia or resting CD4+ cell infection

artículo científico publicado en 2010

Assessing the impact of AGS-004, a dendritic cell-based immunotherapy, and vorinostat on persistent HIV-1 Infection

artículo científico publicado en 2020

BET bromodomain inhibition as a novel strategy for reactivation of HIV-1

artículo científico publicado en 2012

Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation.

artículo científico publicado en 2017

Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy

artículo científico publicado en 2014

Cellular gene modulation of HIV infected CD4 T cells in response to serial treatment with the histone deacetylase (HDAC) inhibitor vorinostat

artículo científico publicado en 2020

Clonal sequences recovered from plasma from patients with residual HIV-1 viremia and on intensified antiretroviral therapy are identical to replicating viral RNAs recovered from circulating resting CD4+ T cells

artículo científico publicado en 2011

Coaxing HIV-1 from resting CD4 T cells: histone deacetylase inhibition allows latent viral expression

artículo científico publicado en 2004

Corrigendum: The differential short- and long-term effects of HIV-1 latency-reversing agents on T cell function

artículo científico publicado en 2016

Curing HIV: Seeking to Target and Clear Persistent Infection

artículo científico publicado en 2020

Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells

artículo científico publicado en 2015

Eliminating Persistent HIV Infection: Getting to the End of the Rainbow

article

Emerging strategies to deplete the HIV reservoir

artículo científico publicado en 2014

Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2.

artículo científico publicado en 2011

Eradicating HIV-1 infection: seeking to clear a persistent pathogen

artículo científico publicado en 2014

Erratum: Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

artículo científico publicado en 2012

Evaluation of EED Inhibitors as a Class of PRC2-Targeted Small Molecules for HIV Latency Reversal

artículo científico publicado en 2020

Expanded cytotoxic T-cell lymphocytes target the latent HIV reservoir

artículo científico publicado en 2015

Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid

artículo científico publicado en 2009

Expression of latent human immunodeficiency type 1 is induced by novel and selective histone deacetylase inhibitors

scientific article published on September 2009

H3K27 Demethylation at the Proviral Promoter Sensitizes Latent HIV to the Effects of Vorinostat in Ex Vivo Cultures of Resting CD4+ T Cells

artículo científico publicado en 2015

HDAC inhibition induces HIV-1 protein and enables immune-based clearance following latency reversal

artículo científico publicado en 2017

HIV latency is reversed by ACSS2-driven histone crotonylation

artículo científico publicado en 2018

HIV-1 infection, response to treatment and establishment of viral latency in a novel humanized T cell-only mouse (TOM) model

artículo científico publicado en 2013

HIV-Specific T Cell Responses Are Highly Stable on Antiretroviral Therapy

artículo científico publicado en 2019

HIV-Specific, Ex Vivo Expanded T Cell Therapy: Feasibility, Safety, and Efficacy in ART-Suppressed HIV-Infected Individuals

article

HLA-B*57 elite suppressor and chronic progressor HIV-1 isolates replicate vigorously and cause CD4+ T cell depletion in humanized BLT mice

scientific article published on 03 January 2014

Human Immunodeficiency Virus Type 1 RNA Detected in the Central Nervous System (CNS) After Years of Suppressive Antiretroviral Therapy Can Originate from a Replicating CNS Reservoir or Clonally Expanded Cells

artículo científico publicado en 2019

Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection

artículo científico publicado en 2012

Immunogenicity of AGS-004 Dendritic Cell Therapy in Patients Treated During Acute HIV Infection

artículo científico publicado en 2017

Impact of biological sex on immune activation and frequency of the latent HIV reservoir during suppressive antiretroviral therapy

artículo científico publicado en 2020

In vivo analysis of the effect of panobinostat on cell-associated HIV RNA and DNA levels and latent HIV infection

artículo científico publicado en 2016

In-vivo administration of histone deacetylase inhibitors does not impair natural killer cell function in HIV+ individuals

scientific article published on 01 March 2019

Interval dosing with the HDAC inhibitor vorinostat effectively reverses HIV latency

artículo científico publicado en 2017

Latent HIV-1 infection of resting CD4⁺ T cells in the humanized Rag2⁻/⁻ γc⁻/⁻ mouse

artículo científico publicado en 2011

Longitudinal dynamics of intact HIV proviral DNA and outgrowth virus frequencies in a cohort of ART-treated individuals

artículo científico publicado en 2020

Measuring the Inducible, Replication-Competent HIV Reservoir Using an Ultra-Sensitive p24 Readout, the Digital ELISA Viral Outgrowth Assay

artículo científico publicado en 2020

Measuring the contribution of γδ T cells to the persistent HIV reservoir

scientific article published on 01 March 2020

New Frontiers in Measuring and Characterizing the HIV Reservoir

scientific article published on 18 December 2019

Peripheral Vγ9Vδ2 T Cells Are a Novel Reservoir of Latent HIV Infection

artículo científico publicado en 2015

Pharmaceutical approaches to eradication of persistent HIV infection

artículo científico publicado en 2009

Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir

artículo científico publicado en 2020

Precise Quantitation of the Latent HIV-1 Reservoir: Implications for Eradication Strategies

artículo científico publicado en 2015

Proviral Latency, Persistent Human Immunodeficiency Virus Infection, and the Development of Latency Reversing Agents.

artículo científico publicado en 2017

Quantification of the Latent HIV-1 Reservoir Using Ultra Deep Sequencing and Primer ID in a Viral Outgrowth Assay

artículo científico publicado en 2016

Quantitation of replication-competent HIV-1 in populations of resting CD4+ T cells

artículo científico publicado en 2014

Reactivation of latent HIV-1 in central memory CD4⁺ T cells through TLR-1/2 stimulation

artículo científico publicado en 2013

SLDAssay: A software package and web tool for analyzing limiting dilution assays

artículo científico publicado en 2017

Selective HDAC inhibition for the disruption of latent HIV-1 infection

artículo científico publicado en 2014

Sequence evaluation and comparative analysis of novel assays for intact proviral HIV-1 DNA

artículo científico publicado en 2020

Staphylococcus aureus Infection in Humanized Mice: A New Model to Study Pathogenicity Associated With Human Immune Response

artículo científico publicado en 2015

Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo

scientific article published on 22 January 2020

Targeted cytotoxic therapy kills persisting HIV infected cells during ART

artículo científico publicado en 2014

The HIV-1 latent reservoir is largely sensitive to circulating T cells

artículo científico publicado en 2020

The Replication-Competent HIV-1 Latent Reservoir is Primarily Established Near the Time of Therapy Initiation: Supplemental Material for Abrahams et al

article

The differential short- and long-term effects of HIV-1 latency-reversing agents on T cell function

artículo científico publicado en 2016

The replication-competent HIV-1 latent reservoir is primarily established near the time of therapy initiation

artículo científico publicado en 2019

Vorinostat Renders the Replication-Competent Latent Reservoir of Human Immunodeficiency Virus (HIV) Vulnerable to Clearance by CD8 T Cells

artículo científico publicado en 2017