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A chronic increase in physical activity inhibits fed-state mTOR/S6K1 signaling and reduces IRS-1 serine phosphorylation in rat skeletal muscle.

scientific article published on February 2008

A moderate acute increase in physical activity enhances nutritive flow and the muscle protein anabolic response to mixed nutrient intake in older adults.

artículo científico publicado en 2012

Addition of carbohydrate or alanine to an essential amino acid mixture does not enhance human skeletal muscle protein anabolism

artículo científico publicado en 2013

Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target of rapamycin signaling

artículo científico publicado en 2007

Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis.

artículo científico publicado en 2011

Amino acids are necessary for the insulin-induced activation of mTOR/S6K1 signaling and protein synthesis in healthy and insulin resistant human skeletal muscle

artículo científico publicado en 2008

An increase in essential amino acid availability upregulates amino acid transporter expression in human skeletal muscle

artículo científico publicado en 2010

Blood flow restriction exercise stimulates mTORC1 signaling and muscle protein synthesis in older men

artículo científico publicado en 2010

Chronic paraplegia-induced muscle atrophy downregulates the mTOR/S6K1 signaling pathway

scientific journal article

Effect of a High-Protein, High-Fiber Beverage Preload on Subjective Appetite Ratings and Subsequent Ad Libitum Energy Intake in Overweight Men and Women: A Randomized, Double-Blind Placebo-Controlled, Crossover Study

artículo científico publicado en 2018

Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women

artículo científico publicado en 2015

Essential amino acid and carbohydrate ingestion before resistance exercise does not enhance postexercise muscle protein synthesis

artículo científico publicado en 2008

Essential amino acids increase microRNA-499, -208b, and -23a and downregulate myostatin and myocyte enhancer factor 2C mRNA expression in human skeletal muscle

scientific article published on 14 October 2009

Excess leucine intake enhances muscle anabolic signaling but not net protein anabolism in young men and women

artículo científico publicado en 2010

Gene and protein expression associated with protein synthesis and breakdown in paraplegic skeletal muscle.

artículo científico publicado en 2008

Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans

artículo científico publicado en 2015

Insulin Stimulates Human Skeletal Muscle Protein Synthesis via an Indirect Mechanism Involving Endothelial-Dependent Vasodilation and Mammalian Target of Rapamycin Complex 1 Signaling.

artículo científico publicado en 2010

Insulin stimulates human skeletal muscle protein synthesis via an indirect mechanism involving endothelial-dependent vasodilation and mammalian target of rapamycin complex 1 signaling

artículo científico publicado en 2010

Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle.

artículo científico publicado en 2007

Mammalian target of rapamycin complex 1 activation is required for the stimulation of human skeletal muscle protein synthesis by essential amino acids

artículo científico publicado en 2011

Muscle protein breakdown has a minor role in the protein anabolic response to essential amino acid and carbohydrate intake following resistance exercise.

artículo científico publicado en 2010

Nutrient signalling in the regulation of human muscle protein synthesis

artículo científico publicado en 2007

Nutritional and contractile regulation of human skeletal muscle protein synthesis and mTORC1 signaling

artículo científico publicado en 2009

Physiological mechanisms of sustained fumagillin-induced weight loss.

artículo científico publicado en 2018

Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis

artículo científico publicado en 2009

Resistance exercise increases human skeletal muscle AS160/TBC1D4 phosphorylation in association with enhanced leg glucose uptake during postexercise recovery.

artículo científico publicado en 2008

Resistance exercise increases leg muscle protein synthesis and mTOR signalling independent of sex

artículo científico publicado en 2010

Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise.

artículo científico publicado en 2011

Skeletal muscle autophagy and protein breakdown following resistance exercise are similar in younger and older adults

artículo científico publicado en 2012

Supraphysiological hyperinsulinaemia is necessary to stimulate skeletal muscle protein anabolism in older adults: evidence of a true age-related insulin resistance of muscle protein metabolism.

artículo científico publicado en 2009