Lista de obras -

1-Mb resolution array-based comparative genomic hybridization using a BAC clone set optimized for cancer gene analysis

artículo científico publicado en 2004

A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines

artículo científico publicado en 2017

A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer

artículo científico publicado en 2020

ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context

artículo científico publicado en 2006

ATARiS: computational quantification of gene suppression phenotypes from multisample RNAi screens

artículo científico publicado en 2012

Abstract 2608: Global integration of knowledgebases for clinical interpretation of cancer variants

Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

artículo científico publicado en 2019

Assessing the clinical utility of cancer genomic and proteomic data across tumor types.

artículo científico publicado en 2014

BREAST CANCER HISTOPATHOLOGY IMAGE ANALYSIS PIPELINE FOR TUMOR PURITY ESTIMATION.

artículo científico publicado en 2017

Boolean calculations made easy (for ribozymes).

artículo científico publicado en 2005

CGHAnalyzer: a stand-alone software package for cancer genome analysis using array-based DNA copy number data

artículo científico publicado en 2005

CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer

artículo científico publicado en 2017

CTNNB1 mutations and overexpression of Wnt/beta-catenin target genes in WT1-mutant Wilms' tumors

artículo científico publicado en 2004

ChIP-on-chip significance analysis reveals large-scale binding and regulation by human transcription factor oncogenes

scholarly article

ChIP-on-chip significance analysis reveals ubiquitous transcription factor binding.

artículo científico publicado en 2007

Chemical Genomics Identifies Small-Molecule MCL1 Repressors and BCL-xL as a Predictor of MCL1 Dependency ⬇️

artículo científico publicado el 17 de abril de 2012

Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis

artículo científico publicado en 2017

Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection

scientific article published on 06 November 2018

Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection

artículo científico publicado en 2015

Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy

article

Deep learning based Nucleus Classification in pancreas histological images.

artículo científico publicado en 2017

Drug susceptibility prediction against a panel of drugs using kernelized Bayesian multitask learning

artículo científico publicado en 2014

Empirical Bayes analysis of quantitative proteomics experiments

artículo científico publicado en 2009

Enabling transparent and collaborative computational analysis of 12 tumor types within The Cancer Genome Atlas

artículo científico publicado en 2013

Functional kinomics identifies candidate therapeutic targets in head and neck cancer

artículo científico publicado en 2014

Functional precision medicine identifies novel druggable targets and therapeutic options in head and neck cancer.

artículo científico publicado en 2018

Genome-Wide Discovery of Modulators of Transcriptional Interactions in Human B Lymphocytes

Genome-wide identification of post-translational modulators of transcription factor activity in human B cells.

artículo científico publicado en 2009

Germline contamination and leakage in whole genome somatic single nucleotide variant detection.

artículo científico publicado en 2018

Global optimization of somatic variant identification in cancer genomes with a global community challenge

artículo científico publicado en 2014

High-resolution detection and mapping of genomic DNA alterations in neuroblastoma

artículo científico publicado en 2005

Identifying the proteins to which small-molecule probes and drugs bind in cells

scholarly article

Improving breast cancer survival analysis through competition-based multidimensional modeling

artículo científico publicado en 2013

Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium

artículo científico publicado en 2016

Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells.

artículo científico publicado en 2009

Integrative Analysis on Histopathological Image for Identifying Cellular Heterogeneity

artículo científico publicado en 2017

Localized Data Fusion for Kernel k-Means Clustering with Application to Cancer Biology ⬇️

artículo científico publicado en 2014

Modeling gene-wise dependencies improves the identification of drug response biomarkers in cancer studies

artículo científico publicado en 2017

Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

artículo científico publicado en 2014

Multiplexed immunohistochemistry image analysis using sparse coding

artículo científico publicado en 2017

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

artículo científico publicado en 2006

PEG10 is a c-MYC target gene in cancer cells

artículo científico publicado en 2006

Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism

artículo científico publicado en 2018

Population-level distribution and putative immunogenicity of cancer neoepitopes

artículo científico publicado en 2018

Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis.

artículo científico publicado en 2017

Quantitative analysis of histological tissue image based on cytological profiles and spatial statistics

artículo científico publicado en 2016

Reverse engineering cellular networks.

artículo científico

SHIFT: speedy histopathological-to-immunofluorescent translation of whole slide images using conditional generative adversarial networks

Simulation studies as designed experiments: the comparison of penalized regression models in the "large p, small n" setting

artículo científico publicado en 2014

Stepwise group sparse regression (SGSR): gene-set-based pharmacogenomic predictive models with stepwise selection of functional priors

artículo científico publicado en 2015

Svpluscnv: analysis and visualization of complex structural variation data

artículo científico publicado en 2020

Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer

artículo científico publicado en 2013

Systematic assessment of analytical methods for drug sensitivity prediction from cancer cell line data

artículo científico publicado en 2014

TBIO-27. GABRIELLA MILLER KIDS FIRST DATA RESOURCE CENTER ADVANCING GENETIC RESEARCH IN CHILDHOOD CANCER AND STRUCTURAL BIRTH DEFECTS THROUGH LARGE SCALE INTEGRATED DATA-DRIVEN DISCOVERY AND CLOUD-BASED PLATFORMS FOR COLLABORATIVE ANALYSIS

The NIH BD2K center for big data in translational genomics

artículo científico publicado en 2015

The Stream algorithm: computationally efficient ridge-regression via Bayesian model averaging, and applications to pharmacogenomic prediction of cancer cell line sensitivity

artículo científico publicado en 2014

The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition

artículo científico publicado en 2015

Theory and limitations of genetic network inference from microarray data

artículo científico publicado en 2007

Toward better benchmarking: challenge-based methods assessment in cancer genomics

artículo científico publicado en 2014

Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemia

artículo científico publicado en 2006

Valection: design optimization for validation and verification studies

scholarly article by Christopher I Cooper published in September 2018

hARACNe: improving the accuracy of regulatory model reverse engineering via higher-order data processing inequality tests

artículo científico publicado en 2013

Lista de obras de

1-Mb resolution array-based comparative genomic hybridization using a BAC clone set optimized for cancer gene analysis

A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines

A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer

ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context

ATARiS: computational quantification of gene suppression phenotypes from multisample RNAi screens

Abstract 2608: Global integration of knowledgebases for clinical interpretation of cancer variants

Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

Assessing the clinical utility of cancer genomic and proteomic data across tumor types.

BREAST CANCER HISTOPATHOLOGY IMAGE ANALYSIS PIPELINE FOR TUMOR PURITY ESTIMATION.

Boolean calculations made easy (for ribozymes).

CGHAnalyzer: a stand-alone software package for cancer genome analysis using array-based DNA copy number data

CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer

CTNNB1 mutations and overexpression of Wnt/beta-catenin target genes in WT1-mutant Wilms' tumors

ChIP-on-chip significance analysis reveals large-scale binding and regulation by human transcription factor oncogenes

ChIP-on-chip significance analysis reveals ubiquitous transcription factor binding.

Chemical Genomics Identifies Small-Molecule MCL1 Repressors and BCL-xL as a Predictor of MCL1 Dependency ⬇️

Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis

Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection

Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection

Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy

Deep learning based Nucleus Classification in pancreas histological images.

Drug susceptibility prediction against a panel of drugs using kernelized Bayesian multitask learning

Empirical Bayes analysis of quantitative proteomics experiments

Enabling transparent and collaborative computational analysis of 12 tumor types within The Cancer Genome Atlas

Functional kinomics identifies candidate therapeutic targets in head and neck cancer

Functional precision medicine identifies novel druggable targets and therapeutic options in head and neck cancer.

Genome-Wide Discovery of Modulators of Transcriptional Interactions in Human B Lymphocytes

Genome-wide identification of post-translational modulators of transcription factor activity in human B cells.

Germline contamination and leakage in whole genome somatic single nucleotide variant detection.

Global optimization of somatic variant identification in cancer genomes with a global community challenge

High-resolution detection and mapping of genomic DNA alterations in neuroblastoma

Identifying the proteins to which small-molecule probes and drugs bind in cells

Improving breast cancer survival analysis through competition-based multidimensional modeling

Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium

Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells.

Integrative Analysis on Histopathological Image for Identifying Cellular Heterogeneity

Localized Data Fusion for Kernel k-Means Clustering with Application to Cancer Biology ⬇️

Modeling gene-wise dependencies improves the identification of drug response biomarkers in cancer studies

Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

Multiplexed immunohistochemistry image analysis using sparse coding

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

PEG10 is a c-MYC target gene in cancer cells

Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism

Population-level distribution and putative immunogenicity of cancer neoepitopes

Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis.

Quantitative analysis of histological tissue image based on cytological profiles and spatial statistics

Reverse engineering cellular networks.

SHIFT: speedy histopathological-to-immunofluorescent translation of whole slide images using conditional generative adversarial networks

Simulation studies as designed experiments: the comparison of penalized regression models in the "large p, small n" setting

Stepwise group sparse regression (SGSR): gene-set-based pharmacogenomic predictive models with stepwise selection of functional priors

Svpluscnv: analysis and visualization of complex structural variation data

Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer

Systematic assessment of analytical methods for drug sensitivity prediction from cancer cell line data

TBIO-27. GABRIELLA MILLER KIDS FIRST DATA RESOURCE CENTER ADVANCING GENETIC RESEARCH IN CHILDHOOD CANCER AND STRUCTURAL BIRTH DEFECTS THROUGH LARGE SCALE INTEGRATED DATA-DRIVEN DISCOVERY AND CLOUD-BASED PLATFORMS FOR COLLABORATIVE ANALYSIS

The NIH BD2K center for big data in translational genomics

The Stream algorithm: computationally efficient ridge-regression via Bayesian model averaging, and applications to pharmacogenomic prediction of cancer cell line sensitivity

The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition

Theory and limitations of genetic network inference from microarray data

Toward better benchmarking: challenge-based methods assessment in cancer genomics

Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemia

Valection: design optimization for validation and verification studies

hARACNe: improving the accuracy of regulatory model reverse engineering via higher-order data processing inequality tests