Lista de obras -

6-Phosphogluconate Dehydrogenase Links Cytosolic Carbohydrate Metabolism to Protein Secretion via Modulation of Glutathione Levels

scientific article published on 13 June 2019

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

artículo científico publicado en 2016

Ablation of insulin receptor substrates 1 and 2 suppresses Kras-driven lung tumorigenesis.

artículo científico publicado en 2018

Absolute Quantification of Matrix Metabolites Reveals the Dynamics of Mitochondrial Metabolism

artículo científico publicado en 2016

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

artículo científico publicado en 2015

Bacteria regulate choanoflagellate development with lipid activators, inhibitors, and synergists

article

Bacterial lipids activate, synergize, and inhibit a developmental switch in choanoflagellates

artículo científico publicado en 2016

Bionectriol A, a polyketide glycoside from the fungus Bionectria sp. associated with the fungus-growing ant, Apterostigma dentigerum ⬇️

artículo científico publicado en 2009

Cholesterol-Independent SREBP-1 Maturation Is Linked to ARF1 Inactivation

artículo científico publicado en 2016

Corrigendum: A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate.

artículo científico publicado en 2016

Critical role for arginase 2 in obesity-associated pancreatic cancer

artículo científico publicado en 2017

Cytoplasmic ATP hydrolysis powers transport of lipopolysaccharide across the periplasm in E. coli

scientific journal article

Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition

artículo científico publicado en 2014

Disruption of Sphingolipid Biosynthesis Blocks Phagocytosis of Candida albicans

artículo científico publicado en 2015

Dynamic redox balance directs the oocyte-to-embryo transition via developmentally controlled reactive cysteine changes

article published in the Proceedings of the National Academy of Sciences of the United States of America

Enhanced phosphocholine metabolism is essential for terminal erythropoiesis

Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin

artículo científico publicado en 2016

Extracellular RNAs Are Associated With Insulin Resistance and Metabolic Phenotypes

artículo científico publicado en 2017

Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging

artículo científico publicado en 2018

Histidine catabolism is a major determinant of methotrexate sensitivity

scientific article published in Nature

JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition

artículo científico publicado en 2018

JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition.

artículo científico publicado en 2018

LACTB is a tumour suppressor that modulates lipid metabolism and cell state

artículo científico publicado en 2017

Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes.

artículo científico publicado en 2017

Metabolic Reprogramming of Pancreatic Cancer Mediated by CDK4/6 Inhibition Elicits Unique Vulnerabilities

artículo científico publicado en 2016

Metabolic Reprogramming of Pancreatic Cancer Mediated by CDK4/6 Inhibition Elicits Unique Vulnerabilities

scientific article published on 01 July 2020

PIK3CA mutant tumors depend on oxoglutarate dehydrogenase

artículo científico publicado en 2017

Periodic production of retinoic acid by meiotic and somatic cells coordinates four transitions in mouse spermatogenesis.

artículo científico publicado en 2017

Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites

artículo científico publicado en 2014

Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase.

artículo científico publicado en 2017

Rapid immunopurification of mitochondria for metabolite profiling and absolute quantification of matrix metabolites

artículo científico publicado en 2017

Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer

scientific article published on 06 December 2019

Regulated assembly of the transenvelope protein complex required for lipopolysaccharide export

artículo científico publicado en 2012

SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.

artículo científico publicado en 2015

Sequence variation in G-protein-coupled receptors: analysis of single nucleotide polymorphisms

artículo científico publicado en 2005

Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death

artículo científico publicado en 2019

Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming.

artículo científico publicado en 2017

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells.

artículo científico publicado en 2015

Targeting tumor phenotypic plasticity and metabolic remodeling in adaptive cross-drug tolerance

scientific article published on 20 August 2019

The complex that inserts lipopolysaccharide into the bacterial outer membrane forms a two-protein plug-and-barrel

artículo científico publicado en 2011

The protein synthesis inhibitor blasticidin s enters mammalian cells via leucine-rich repeat-containing protein 8D.

artículo científico publicado en 2014

Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers

artículo científico publicado en 2016

Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential

artículo científico publicado en 2016

mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient.

artículo científico publicado en 2017

mTORC1 is Required for Brown Adipose Tissue Recruitment and Metabolic Adaptation to Cold.

artículo científico publicado en 2016

Lista de obras de

6-Phosphogluconate Dehydrogenase Links Cytosolic Carbohydrate Metabolism to Protein Secretion via Modulation of Glutathione Levels

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

Ablation of insulin receptor substrates 1 and 2 suppresses Kras-driven lung tumorigenesis.

Absolute Quantification of Matrix Metabolites Reveals the Dynamics of Mitochondrial Metabolism

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

Bacteria regulate choanoflagellate development with lipid activators, inhibitors, and synergists

Bacterial lipids activate, synergize, and inhibit a developmental switch in choanoflagellates

Bionectriol A, a polyketide glycoside from the fungus Bionectria sp. associated with the fungus-growing ant, Apterostigma dentigerum ⬇️

Cholesterol-Independent SREBP-1 Maturation Is Linked to ARF1 Inactivation

Corrigendum: A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate.

Critical role for arginase 2 in obesity-associated pancreatic cancer

Cytoplasmic ATP hydrolysis powers transport of lipopolysaccharide across the periplasm in E. coli

Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition

Disruption of Sphingolipid Biosynthesis Blocks Phagocytosis of Candida albicans

Dynamic redox balance directs the oocyte-to-embryo transition via developmentally controlled reactive cysteine changes

Enhanced phosphocholine metabolism is essential for terminal erythropoiesis

Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin

Extracellular RNAs Are Associated With Insulin Resistance and Metabolic Phenotypes

Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging

Histidine catabolism is a major determinant of methotrexate sensitivity

JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition

JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition.

LACTB is a tumour suppressor that modulates lipid metabolism and cell state

Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes.

Metabolic Reprogramming of Pancreatic Cancer Mediated by CDK4/6 Inhibition Elicits Unique Vulnerabilities

Metabolic Reprogramming of Pancreatic Cancer Mediated by CDK4/6 Inhibition Elicits Unique Vulnerabilities

PIK3CA mutant tumors depend on oxoglutarate dehydrogenase

Periodic production of retinoic acid by meiotic and somatic cells coordinates four transitions in mouse spermatogenesis.

Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites

Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase.

Rapid immunopurification of mitochondria for metabolite profiling and absolute quantification of matrix metabolites

Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer

Regulated assembly of the transenvelope protein complex required for lipopolysaccharide export

SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.

Sequence variation in G-protein-coupled receptors: analysis of single nucleotide polymorphisms

Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death

Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming.

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells.

Targeting tumor phenotypic plasticity and metabolic remodeling in adaptive cross-drug tolerance

The complex that inserts lipopolysaccharide into the bacterial outer membrane forms a two-protein plug-and-barrel

The protein synthesis inhibitor blasticidin s enters mammalian cells via leucine-rich repeat-containing protein 8D.

Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers

Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential

mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient.

mTORC1 is Required for Brown Adipose Tissue Recruitment and Metabolic Adaptation to Cold.