Lista de obras -

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

artículo científico publicado en 2011

A soluble α-synuclein construct forms a dynamic tetramer

artículo científico publicado en 2011

Correction: Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue.

artículo científico publicado en 2012

Detection of endogenous S1292 LRRK2 autophosphorylation in mouse tissue as a readout for kinase activity.

artículo científico publicado en 2018

Differences in Stability, Activity and Mutation Effects Between Human and Mouse Leucine-Rich Repeat Kinase 2

artículo científico publicado en 2018

Divergent Effects of G2019S and R1441C LRRK2 Mutations on LRRK2 and Rab10 Phosphorylations in Mouse Tissues

artículo científico publicado en 2020

Extracellular clusterin limits the uptake of α-synuclein fibrils by murine and human astrocytes

artículo científico publicado en 2020

Hexokinase activity is required for recruitment of parkin to depolarized mitochondria

artículo científico publicado en 2014

LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies

artículo científico publicado en 2020

Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4

scientific article published on 27 October 2018

Molecular changes in the absence of severe pathology in the pulvinar in dementia with Lewy bodies

scientific article published on 23 March 2018

Mutations in LRRK2/dardarin associated with Parkinson disease are more toxic than equivalent mutations in the homologous kinase LRRK1.

artículo científico publicado en 2007

Pathogenic LRRK2 mutations do not alter gene expression in cell model systems or human brain tissue

artículo científico publicado en 2011

Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7

artículo científico publicado en 2014

The G2385R risk factor for Parkinson's disease enhances CHIP-dependent intracellular degradation of LRRK2.

artículo científico publicado en 2017

The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutation

artículo científico publicado en 2012

The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation

artículo científico publicado en 2008

The Parkinson's Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network

artículo científico publicado en 2020

The Parkinson's disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylation

artículo científico publicado en 2010

Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils

artículo científico publicado en 2019

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

artículo científico publicado en 2014

Lista de obras de

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

A soluble α-synuclein construct forms a dynamic tetramer

Correction: Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue.

Detection of endogenous S1292 LRRK2 autophosphorylation in mouse tissue as a readout for kinase activity.

Differences in Stability, Activity and Mutation Effects Between Human and Mouse Leucine-Rich Repeat Kinase 2

Divergent Effects of G2019S and R1441C LRRK2 Mutations on LRRK2 and Rab10 Phosphorylations in Mouse Tissues

Extracellular clusterin limits the uptake of α-synuclein fibrils by murine and human astrocytes

Hexokinase activity is required for recruitment of parkin to depolarized mitochondria

LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies

Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4

Molecular changes in the absence of severe pathology in the pulvinar in dementia with Lewy bodies

Mutations in LRRK2/dardarin associated with Parkinson disease are more toxic than equivalent mutations in the homologous kinase LRRK1.

Pathogenic LRRK2 mutations do not alter gene expression in cell model systems or human brain tissue

Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7

The G2385R risk factor for Parkinson's disease enhances CHIP-dependent intracellular degradation of LRRK2.

The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutation

The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation

The Parkinson's Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network

The Parkinson's disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylation

Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease