Lista de obras -

A clonal hypereosinophilic syndrome with specific and effective therapy: a report of two cases

artículo científico publicado en 2006

A new MALDI-TOF-based assay for monitoring JAK2 V617F mutation level in patients undergoing allogeneic stem cell transplantation (allo SCT) for classic myeloproliferative disorders (MPD).

artículo científico publicado en 2007

A role for common fragile site induction in amplification of human oncogenes

artículo científico publicado en 2002

Absence of negative growth regulation in three new murine radiation-induced myeloid leukemia cell lines with deletion of chromosome 2

artículo científico publicado en 1992

Acquisition of a Ph chromosome with minor BCR/ABL fusion in treatment-related myelodysplastic syndrome with chromosome 7 abnormalities in a patient treated for Hodgkin disease

artículo científico publicado en 2005

Amplification of band q22 of chromosome 21, including AML1, in older children with acute lymphoblastic leukemia: an emerging molecular cytogenetic subgroup

artículo científico publicado en 2003

Apaf1 in chronic myelogenous leukemia (CML) progression: reduced Apaf1 expression is correlated with a H179R p53 mutation during clinical blast crisis.

artículo científico publicado en 2007

Assessment of the response to imatinib in chronic myeloid leukemia patients--comparison between the FISH, multiplex and RT-PCR methods.

artículo científico publicado en 2004

BCR-ABL transcripts are not detected in cord blood or the peripheral blood of the newborn child whose mother developed chronic myeloid leukemia while pregnant.

artículo científico publicado en 2009

COMBO-FISH for focussed fluorescence labelling of gene domains: 3D-analysis of the genome architecture of abl and bcr in human blood cells

artículo científico publicado en 2005

Cellular and molecular characteristics of an immortalized ataxia-telangiectasia (group AB) cell line

artículo científico publicado en 1989

Characterizing T cells in SCID patients presenting with reactive or residual T lymphocytes.

artículo científico publicado en 2012

Chimerism testing and detection of minimal residual disease after allogeneic hematopoietic transplantation using the bioView (Duet) combined morphological and cytogenetical analysis

artículo científico publicado en 2002

Chromosomal mapping of the murine c-abl proto-oncogene by in situ hybridization

artículo científico publicado en 1990

Chromosomal numerical aberrations in apparently normal oral mucosa of heavy smokers affected by lung cancer

artículo científico publicado en 2009

Chromosomal numerical aberrations in oral lichen planus

artículo científico publicado en 2009

Chromosome 13q deletion and IgH abnormalities may be both masked by near-tetraploidy in a high proportion of multiple myeloma patients: a combined morphology and I-FISH analysis.

artículo científico publicado en 2007

Clonal expansion and not cell interconversion is the basis for the neuroblast and nonneuronal types of the SK-N-SH neuroblastoma cell line ⬇️

artículo científico publicado el 1 de mayo de 2003

Clonal expansion of a new MLL rearrangement in the absence of leukemia

artículo científico publicado en 2005

Co-existence of clonal expanded autologous and transplacental-acquired maternal T cells in recombination activating gene-deficient severe combined immunodeficiency

artículo científico publicado en 2014

Co-existence of multiple subclones in TEL-AML1 at diagnosis of acute lymphoblastic leukaemia in association with submicroscopic deletion of AML1.

artículo científico publicado en 2005

Coexistence of several unbalanced translocations in a case of neuroblastoma: the contribution of multicolor spectral karyotyping

artículo científico

Combined analysis of morphology and fluorescence in situ hybridization in follow-up of minimal residual disease in a child with Philadelphia-positive acute lymphoblastic leukemia

artículo científico publicado en 2002

Comparison of triple helical COMBO-FISH and standard FISH by means of quantitative microscopic image analysis of abl/bcr positions in cell nuclei

artículo científico

Correlation between losses of IGH or its segments and deletions of 13q14 in t(11;14) (q13;q32) multiple myeloma

artículo científico publicado en 2010

Could rhG-CSF induction of tetraploidy contribute to leukemogenesis in healthy donors?

artículo científico publicado en 2007

Cytogenetic studies on B-cell leukemias of AKR origin

artículo científico publicado en 1987

Deletion of chromosome 2 is an early event in the development of radiation-induced myeloid leukemia in SJL/J mice

scientific article published on 01 August 1988

Demonstration of Thymopoietin Transcripts in Different Hematopoietic Cell Lines ⬇️

artículo científico publicado el 1 de enero de 1995

Detection of non-diploid cells in premalignant and malignant oral lesions using combined morphological and FISH analysis - a new method for early detection of suspicious oral lesions

artículo científico publicado en 2007

Detection of unidentified chromosome abnormalities in human neuroblastoma by spectral karyotyping (SKY).

artículo científico

Determination of chromosome 13 status in bone marrow cells of patients with multiple myeloma using combined morphologic and fluorescence in situ hybridization analysis

artículo científico publicado en 2004

Diagnosis of Relapsed Burkitt's Lymphoma in a Urine Sample: an Unusual "FISHing" Expedition

artículo científico publicado en 2015

Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient

artículo científico publicado en 2009

Evolution of p53 in hypoxia-stressed Spalax mimics human tumor mutation

scholarly article

Evolutionary regulation of the blind subterranean mole rat, Spalax, revealed by genome-wide gene expression

artículo científico publicado en 2005

Fast‐FISH Detection and Semi‐Automated Image Analysis of Numerical Chromosome Aberrations in Hematological Malignancies ⬇️

artículo científico publicado el 1 de enero de 1998

Fluorescence lifetime imaging of DAPI-stained nuclei as a novel diagnostic tool for the detection and classification of B-cell chronic lymphocytic leukemia

artículo científico publicado en 2016

Gene expression profiles of AML derived stem cells; similarity to hematopoietic stem cells

artículo científico publicado en 2006

Hairy cell leukemia-variant without typical morphology and with near-tetraploid DNA content.

artículo científico publicado en 2016

Hexasomy of chromosome 8 and trisomy of chromosome 11 characterize two karyotypically independent clones in a case of acute non-lymphocytic leukemia. Conventional cytogenetic and FISH investigation.

artículo científico publicado en 1995

Hyperphosphatemia during spontaneous tumor lysis syndrome culminate in severe hypophosphatemia at the time of blast crisis of Phneg CML to acute myelomoncytic leukemia

artículo científico publicado en 2012

Identification of a region in glycoprotein IIIa involved in subunit association with glycoprotein IIb: further lessons from Iraqi-Jewish Glanzmann thrombasthenia

artículo científico publicado en 2001

Immature leukemic CD34+CXCR4+ cells from CML patients have lower integrin-dependent migration and adhesion in response to the chemokine SDF-1.

artículo científico publicado en 2002

In vitro proliferative advantage of bone marrow cells with tetrasomy 8 in Ewing sarcoma

artículo científico publicado en 1996

Induction of polyploidy by nuclear fusion mechanism upon decreased expression of the nuclear envelope protein LAP2β in the human osteosarcoma cell line U2OS.

artículo científico publicado en 2014

Interphase fluorescence in situ hybridization detection of chromosome 17 and 17q region gains in neuroblastoma: are they secondary events?

scientific article published on 01 September 2002

Involvement of der(12)t(12;21)(p13;q22) and as well as additional rearrangements of chromosome 12 homolog in ETV6/RUNX1-positive acute lymphoblastic leukemia

artículo científico publicado en 2009

Is fluorescence in-situ hybridization sufficient in patients with myelodysplastic syndromes and insufficient cytogenetic testing?

artículo científico publicado en 2018

Karyotypic evolution pathways in medulloblastoma/primitive neuroectodermal tumor determined with a combination of spectral karyotyping, G-banding, and fluorescence in situ hybridization.

artículo científico publicado en 2004

Large-scale analysis of chromosomal aberrations in cancer karyotypes reveals two distinct paths to aneuploidy ⬇️

artículo científico publicado el 29 de junio de 2011

Malignant transformation of normal enterocytes following downregulation of Bak expression

scientific journal article

Multilineage hematopoietic engraftment after allogeneic peripheral blood stem cell transplantation without conditioning in SCID patients

artículo científico publicado en 2004

Multiple Myeloma Presenting in Patients Younger than 50 Years of Age: A Single Institution Experience

artículo científico publicado en 2020

Neural expression and chromosomal mapping of Neu differentiation factor to 8p12-p21

artículo científico publicado en 1993

New insights to the MLL recombinome of acute leukemias

artículo científico publicado en 2009

Newly diagnosed multiple myeloma patients carrying monoallelic deletion of the whole locus of immunoglobulin heavy chain gene have a better prognosis compared to those with t(4;14) and t(14;16)

scientific article published on 06 February 2019

Noninvasive detection of aneuploid cells in laryngeal epithelial precursor lesions

artículo científico publicado en 2011

Oral lichen planus patients exhibit consistent chromosomal numerical aberrations: A follow-up analysis

artículo científico publicado en 2015

P53 in blind subterranean mole rats--loss-of-function versus gain-of-function activities on newly cloned Spalax target genes

artículo científico publicado en 2006

Philadelphia-chromosome-positive T-lymphoblastic leukemia: acute leukemia or chronic myelogenous leukemia blastic crisis

artículo científico publicado en 2005

Polyploidization of Murine Mesenchymal Cells Is Associated with Suppression of the Long Noncoding RNA H19 and Reduced Tumorigenicity ⬇️

artículo científico publicado el 9 de octubre de 2012

Post-essential thrombocythemia myelofibrosis and chronic myelomonocytic leukemia can co-exist with complex cytogenetic abnormalities

artículo científico publicado en 2010

Preleukemia in experimental leukemogenesis.

artículo científico publicado en 1989

Preleukemia in long-term plasmacytoma-regressor mice

artículo científico publicado el 29 de mayo de 1998

Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cells via TopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangements.

artículo científico publicado en 2016

Reciprocal relationship between a Ph-negative clone with trisomy 8 associated with severe myelodysplasia and a Ph-positive clone following imatinib treatment in a patient with accelerated-phase chronic myelogenous leukemia (CML).

artículo científico publicado en 2004

Reduced expression of plakoglobin correlates with adverse outcome in patients with neuroblastoma.

artículo científico publicado en 2001

SKY analysis of childhood neural tumors and cell lines demonstrates a susceptibility of aberrant chromosomes to further rearrangements.

artículo científico publicado en 2006

SKY detection of chromosome rearrangements in two cases of tMDS with a complex karyotype

artículo científico publicado en 2002

SKY reveals a high frequency of unbalanced translocations involving chromosome 6 in t(12;21)-positive acute lymphoblastic leukemia

scientific article published on 06 April 2007

SMURF2 prevents detrimental changes to chromatin, protecting human dermal fibroblasts from chromosomal instability and tumorigenesis

artículo científico publicado en 2020

Severe eosinophilia in children: a diagnostic dilemma.

artículo científico publicado en 2013

Simultaneous detection of deletions of 9q and 22q in a subgroup of chronic myelocytic leukemia Philadelphia-positive patients by a novel probe

artículo científico publicado en 2003

Standardization criteria for the detection of BCR/ABL fusion in interphase nuclei of chronic myelogenous leukemia patients by fluorescence in situ hybridization

artículo científico publicado en 2000

Subgroup of patients with Philadelphia-positive chronic myelogenous leukemia characterized by a deletion of 9q proximal to ABL gene: expression profiling, resistance to interferon therapy, and poor prognosis.

artículo científico publicado en 2001

Sustained Response to Imatinib in a Pediatric Patient with Concurrent Myeloproliferative Disease and Lymphoblastic Lymphoma Associated with a CCDC88C-PDGFRB Fusion Gene

scientific article published on 06 February 2019

Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer

artículo científico publicado en 2017

Tetraploid myeloid cells in donors of peripheral blood stem cells treated with rhG-CSF

artículo científico publicado en 2003

The MLL recombinome of acute leukemias in 2013.

artículo científico publicado en 2013

The MLL recombinome of acute leukemias in 2017.

artículo científico

The SIL gene is essential for mitotic entry and survival of cancer cells.

artículo científico publicado en 2007

The increased expression of 14q32 small nucleolar RNA transcripts in promyelocytic leukemia cells is not dependent on PML–RARA fusion gene ⬇️

artículo científico publicado el 12 de octubre de 2012

The multiparametric scanning system for evaluation of minimal residual disease in hematological malignancies

artículo científico publicado en 2004

The presence of a single PML-RARA isoform lacking exon 5 in FISH-negative APL samples

artículo científico publicado en 2007

Therapy-related acute myeloid leukemia with t(2;11)(q37;q23) after treatment for osteosarcoma.

artículo científico publicado en 2010

Three-dimensional spectral precision distance microscopy of chromatin nanostructures after triple-colour DNA labelling: a study of the BCR region on chromosome 22 and the Philadelphia chromosome

artículo científico publicado en 2000

Translocation t(11;14) in newly diagnosed patients with multiple myeloma: Is it always favorable?

artículo científico publicado en 2016

Treatment with interferon alpha prior to discontinuation of imatinib in patients with chronic myeloid leukemia

artículo científico publicado en 2011

Lista de obras de

A clonal hypereosinophilic syndrome with specific and effective therapy: a report of two cases

A new MALDI-TOF-based assay for monitoring JAK2 V617F mutation level in patients undergoing allogeneic stem cell transplantation (allo SCT) for classic myeloproliferative disorders (MPD).

A role for common fragile site induction in amplification of human oncogenes

Absence of negative growth regulation in three new murine radiation-induced myeloid leukemia cell lines with deletion of chromosome 2

Acquisition of a Ph chromosome with minor BCR/ABL fusion in treatment-related myelodysplastic syndrome with chromosome 7 abnormalities in a patient treated for Hodgkin disease

Amplification of band q22 of chromosome 21, including AML1, in older children with acute lymphoblastic leukemia: an emerging molecular cytogenetic subgroup

Apaf1 in chronic myelogenous leukemia (CML) progression: reduced Apaf1 expression is correlated with a H179R p53 mutation during clinical blast crisis.

Assessment of the response to imatinib in chronic myeloid leukemia patients--comparison between the FISH, multiplex and RT-PCR methods.

BCR-ABL transcripts are not detected in cord blood or the peripheral blood of the newborn child whose mother developed chronic myeloid leukemia while pregnant.

COMBO-FISH for focussed fluorescence labelling of gene domains: 3D-analysis of the genome architecture of abl and bcr in human blood cells

Cellular and molecular characteristics of an immortalized ataxia-telangiectasia (group AB) cell line

Characterizing T cells in SCID patients presenting with reactive or residual T lymphocytes.

Chimerism testing and detection of minimal residual disease after allogeneic hematopoietic transplantation using the bioView (Duet) combined morphological and cytogenetical analysis

Chromosomal mapping of the murine c-abl proto-oncogene by in situ hybridization

Chromosomal numerical aberrations in apparently normal oral mucosa of heavy smokers affected by lung cancer

Chromosomal numerical aberrations in oral lichen planus

Chromosome 13q deletion and IgH abnormalities may be both masked by near-tetraploidy in a high proportion of multiple myeloma patients: a combined morphology and I-FISH analysis.

Clonal expansion and not cell interconversion is the basis for the neuroblast and nonneuronal types of the SK-N-SH neuroblastoma cell line ⬇️

Clonal expansion of a new MLL rearrangement in the absence of leukemia

Co-existence of clonal expanded autologous and transplacental-acquired maternal T cells in recombination activating gene-deficient severe combined immunodeficiency

Co-existence of multiple subclones in TEL-AML1 at diagnosis of acute lymphoblastic leukaemia in association with submicroscopic deletion of AML1.

Coexistence of several unbalanced translocations in a case of neuroblastoma: the contribution of multicolor spectral karyotyping

Combined analysis of morphology and fluorescence in situ hybridization in follow-up of minimal residual disease in a child with Philadelphia-positive acute lymphoblastic leukemia

Comparison of triple helical COMBO-FISH and standard FISH by means of quantitative microscopic image analysis of abl/bcr positions in cell nuclei

Correlation between losses of IGH or its segments and deletions of 13q14 in t(11;14) (q13;q32) multiple myeloma

Could rhG-CSF induction of tetraploidy contribute to leukemogenesis in healthy donors?

Cytogenetic studies on B-cell leukemias of AKR origin

Deletion of chromosome 2 is an early event in the development of radiation-induced myeloid leukemia in SJL/J mice

Demonstration of Thymopoietin Transcripts in Different Hematopoietic Cell Lines ⬇️

Detection of non-diploid cells in premalignant and malignant oral lesions using combined morphological and FISH analysis - a new method for early detection of suspicious oral lesions

Detection of unidentified chromosome abnormalities in human neuroblastoma by spectral karyotyping (SKY).

Determination of chromosome 13 status in bone marrow cells of patients with multiple myeloma using combined morphologic and fluorescence in situ hybridization analysis

Diagnosis of Relapsed Burkitt's Lymphoma in a Urine Sample: an Unusual "FISHing" Expedition

Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient

Evolution of p53 in hypoxia-stressed Spalax mimics human tumor mutation

Evolutionary regulation of the blind subterranean mole rat, Spalax, revealed by genome-wide gene expression

Fast‐FISH Detection and Semi‐Automated Image Analysis of Numerical Chromosome Aberrations in Hematological Malignancies ⬇️

Fluorescence lifetime imaging of DAPI-stained nuclei as a novel diagnostic tool for the detection and classification of B-cell chronic lymphocytic leukemia

Gene expression profiles of AML derived stem cells; similarity to hematopoietic stem cells

Hairy cell leukemia-variant without typical morphology and with near-tetraploid DNA content.

Hexasomy of chromosome 8 and trisomy of chromosome 11 characterize two karyotypically independent clones in a case of acute non-lymphocytic leukemia. Conventional cytogenetic and FISH investigation.

Hyperphosphatemia during spontaneous tumor lysis syndrome culminate in severe hypophosphatemia at the time of blast crisis of Phneg CML to acute myelomoncytic leukemia

Identification of a region in glycoprotein IIIa involved in subunit association with glycoprotein IIb: further lessons from Iraqi-Jewish Glanzmann thrombasthenia

Immature leukemic CD34+CXCR4+ cells from CML patients have lower integrin-dependent migration and adhesion in response to the chemokine SDF-1.

In vitro proliferative advantage of bone marrow cells with tetrasomy 8 in Ewing sarcoma

Induction of polyploidy by nuclear fusion mechanism upon decreased expression of the nuclear envelope protein LAP2β in the human osteosarcoma cell line U2OS.

Interphase fluorescence in situ hybridization detection of chromosome 17 and 17q region gains in neuroblastoma: are they secondary events?

Involvement of der(12)t(12;21)(p13;q22) and as well as additional rearrangements of chromosome 12 homolog in ETV6/RUNX1-positive acute lymphoblastic leukemia

Is fluorescence in-situ hybridization sufficient in patients with myelodysplastic syndromes and insufficient cytogenetic testing?

Karyotypic evolution pathways in medulloblastoma/primitive neuroectodermal tumor determined with a combination of spectral karyotyping, G-banding, and fluorescence in situ hybridization.

Large-scale analysis of chromosomal aberrations in cancer karyotypes reveals two distinct paths to aneuploidy ⬇️

Malignant transformation of normal enterocytes following downregulation of Bak expression

Multilineage hematopoietic engraftment after allogeneic peripheral blood stem cell transplantation without conditioning in SCID patients

Multiple Myeloma Presenting in Patients Younger than 50 Years of Age: A Single Institution Experience

Neural expression and chromosomal mapping of Neu differentiation factor to 8p12-p21

New insights to the MLL recombinome of acute leukemias

Newly diagnosed multiple myeloma patients carrying monoallelic deletion of the whole locus of immunoglobulin heavy chain gene have a better prognosis compared to those with t(4;14) and t(14;16)

Noninvasive detection of aneuploid cells in laryngeal epithelial precursor lesions

Oral lichen planus patients exhibit consistent chromosomal numerical aberrations: A follow-up analysis

P53 in blind subterranean mole rats--loss-of-function versus gain-of-function activities on newly cloned Spalax target genes

Philadelphia-chromosome-positive T-lymphoblastic leukemia: acute leukemia or chronic myelogenous leukemia blastic crisis

Polyploidization of Murine Mesenchymal Cells Is Associated with Suppression of the Long Noncoding RNA H19 and Reduced Tumorigenicity ⬇️

Post-essential thrombocythemia myelofibrosis and chronic myelomonocytic leukemia can co-exist with complex cytogenetic abnormalities

Preleukemia in experimental leukemogenesis.

Preleukemia in long-term plasmacytoma-regressor mice

Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cells via TopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangements.

Reciprocal relationship between a Ph-negative clone with trisomy 8 associated with severe myelodysplasia and a Ph-positive clone following imatinib treatment in a patient with accelerated-phase chronic myelogenous leukemia (CML).

Reduced expression of plakoglobin correlates with adverse outcome in patients with neuroblastoma.

SKY analysis of childhood neural tumors and cell lines demonstrates a susceptibility of aberrant chromosomes to further rearrangements.

SKY detection of chromosome rearrangements in two cases of tMDS with a complex karyotype

SKY reveals a high frequency of unbalanced translocations involving chromosome 6 in t(12;21)-positive acute lymphoblastic leukemia

SMURF2 prevents detrimental changes to chromatin, protecting human dermal fibroblasts from chromosomal instability and tumorigenesis

Severe eosinophilia in children: a diagnostic dilemma.

Simultaneous detection of deletions of 9q and 22q in a subgroup of chronic myelocytic leukemia Philadelphia-positive patients by a novel probe

Standardization criteria for the detection of BCR/ABL fusion in interphase nuclei of chronic myelogenous leukemia patients by fluorescence in situ hybridization

Subgroup of patients with Philadelphia-positive chronic myelogenous leukemia characterized by a deletion of 9q proximal to ABL gene: expression profiling, resistance to interferon therapy, and poor prognosis.

Sustained Response to Imatinib in a Pediatric Patient with Concurrent Myeloproliferative Disease and Lymphoblastic Lymphoma Associated with a CCDC88C-PDGFRB Fusion Gene

Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer

Tetraploid myeloid cells in donors of peripheral blood stem cells treated with rhG-CSF