Lista de obras -

5-Azacytidine, a DNA methyltransferase inhibitor, induces ATR-mediated DNA double-strand break responses, apoptosis, and synergistic cytotoxicity with doxorubicin and bortezomib against multiple myeloma cells.

artículo científico publicado en 2007

A Systematic Analysis of Peptide Linker Length and Liposomal Polyethylene Glycol Coating on Cellular Uptake of Peptide-Targeted Liposomes ⬇️

artículo científico publicado el 5 de marzo de 2013

A dual-color fluorescence imaging-based system for the dissection of antiangiogenic and chemotherapeutic activity of molecules

artículo científico publicado en 2004

Aggresome induction by proteasome inhibitor bortezomib and alpha-tubulin hyperacetylation by tubulin deacetylase (TDAC) inhibitor LBH589 are synergistic in myeloma cells

artículo científico publicado en 2006

Antibody purification via affinity membrane chromatography method utilizing nucleotide binding site targeting with a small molecule.

artículo científico publicado en 2016

BIRB 796 enhances cytotoxicity triggered by bortezomib, heat shock protein (Hsp) 90 inhibitor, and dexamethasone via inhibition of p38 mitogen-activated protein kinase/Hsp27 pathway in multiple myeloma cell lines and inhibits paracrine tumour growth

artículo científico publicado en 2006

Biologic sequelae of I{kappa}B kinase (IKK) inhibition in multiple myeloma: therapeutic implications

artículo científico publicado en 2009

Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma

artículo científico publicado en 2012

Covalent Heterobivalent Inhibitor Design for Inhibition of IgE-Dependent Penicillin Allergy in a Murine Model

scientific article published on 17 May 2019

Delineation of the Chemical Pathways Underlying Nitric Oxide-Induced Homologous Recombination in Mammalian Cells

artículo científico publicado en 2005

Design of a heterobivalent ligand to inhibit IgE clustering on mast cells

artículo científico publicado en 2011

Design of a heterotetravalent synthetic allergen that reflects epitope heterogeneity and IgE antibody variability to study mast cell degranulation ⬇️

artículo científico publicado el 1 de enero de 2013

Designer covalent heterobivalent inhibitors prevent IgE-dependent responses to peanut allergen

scientific article published on 08 April 2019

Determination of Crucial Immunogenic Epitopes in Major Peanut Allergy Protein, Ara h2, via Novel Nanoallergen Platform

artículo científico publicado en 2017

Didox, a ribonucleotide reductase inhibitor, induces apoptosis and inhibits DNA repair in multiple myeloma cells

artículo científico publicado en 2006

Dual Carfilzomib and Doxorubicin-Loaded Liposomal Nanoparticles for Synergistic Efficacy in Multiple Myeloma

artículo científico publicado en 2016

Dual-receptor targeted strategy in nanoparticle design achieves tumor cell selectivity through cooperativity

scientific article published on 01 March 2019

Engineering peptide-targeted liposomal nanoparticles optimized for improved selectivity for HER2-positive breast cancer cells to achieve enhanced in vivo efficacy

artículo científico publicado en 2020

Enhancement of antibody selectivity via bicyclic complex formation

artículo científico

Erratum: In vivo and in vitro cytotoxicity of R-etodolac with dexamethasone in glucocorticoid-resistant multiple myeloma cells

artículo científico

Fatty acid synthase is a novel therapeutic target in multiple myeloma

artículo científico publicado en 2008

Glycome and transcriptome regulation of vasculogenesis

artículo científico publicado en 2009

High dose of Zoledronic acid inhibits both osteoclasts and osteoblasts in an In Vivo mouse model

High-dose zoledronic acid impacts bone remodeling with effects on osteoblastic lineage and bone mechanical properties

artículo científico publicado en 2009

Identification of a moderate affinity CD22 binding peptide and in vitro optimization of peptide-targeted nanoparticles for selective uptake by CD22+ B-cell malignancies

artículo científico publicado en 2020

Improved Peptide-Targeted Liposome Design Through Optimized Peptide Hydrophilicity, Ethylene Glycol Linker Length, and Peptide Density

artículo científico publicado en 2015

In vivo and in vitro cytotoxicity of R-etodolac with dexamethasone in glucocorticoid-resistant multiple myeloma cells.

artículo científico publicado en 2006

In vivo evaluation of CD38 and CD138 as targets for nanoparticle-based drug delivery in multiple myeloma

scientific article published on 02 November 2020

Inhibition of Akt induces significant downregulation of survivin and cytotoxicity in human multiple myeloma cells

artículo científico publicado en 2007

Inhibition of weak-affinity epitope-IgE interactions prevents mast cell degranulation

artículo científico publicado en 2013

JS-K has potent anti-angiogenic activity in vitro and inhibits tumour angiogenesis in a multiple myeloma model in vivo.

artículo científico publicado en 2010

JS-K, a GST-activated nitric oxide generator, induces DNA double-strand breaks, activates DNA damage response pathways, and induces apoptosis in vitro and in vivo in human multiple myeloma cells

artículo científico publicado en 2007

Ligand-targeted liposome design: challenges and fundamental considerations.

artículo científico publicado en 2013

Liposomal bortezomib nanoparticles via boronic ester prodrug formulation for improved therapeutic efficacy in vivo.

artículo científico publicado en 2014

Liposomal carfilzomib nanoparticles effectively target multiple myeloma cells and demonstrate enhanced efficacy in vivo.

artículo científico publicado en 2014

MLN3897, a novel CCR1 inhibitor, impairs osteoclastogenesis and inhibits the interaction of multiple myeloma cells and osteoclasts.

artículo científico publicado en 2007

Micellar nanoparticle formation via electrostatic interactions for delivering multinuclear platinum(II) drugs

artículo científico publicado en 2013

Molecular cloning of the heparin/heparan sulfate delta 4,5 unsaturated glycuronidase from Flavobacterium heparinum, its recombinant expression in Escherichia coli, and biochemical determination of its unique substrate specificity

artículo científico publicado en 2002

Nanoallergens: A multivalent platform for studying and evaluating potency of allergen epitopes in cellular degranulation

artículo científico publicado en 2016

Novel etodolac analog SDX-308 (CEP-18082) induces cytotoxicity in multiple myeloma cells associated with inhibition of beta-catenin/TCF pathway.

artículo científico publicado en 2007

Optimizing design parameters of a peptide targeted liposomal nanoparticle in an in vivo multiple myeloma disease model after initial evaluation in vitro

scientific article published on 29 August 2019

Oriented surface immobilization of antibodies at the conserved nucleotide binding site for enhanced antigen detection.

artículo científico publicado en 2012

PI3K/p110{delta} is a novel therapeutic target in multiple myeloma

artículo científico publicado en 2010

Photosensitive Pt(IV)-azide prodrug-loaded nanoparticles exhibit controlled drug release and enhanced efficacy in vivo

artículo científico publicado en 2014

Preclinical activity of P276-00, a novel small-molecule cyclin-dependent kinase inhibitor in the therapy of multiple myeloma

artículo científico publicado en 2009

Rationally engineered nanoparticles target multiple myeloma cells, overcome cell-adhesion-mediated drug resistance, and show enhanced efficacy in vivo ⬇️

artículo científico publicado el 20 de abril de 2012

SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK

artículo científico publicado en 2008

Selective photocrosslinking of functional ligands to antibodies via the conserved nucleotide binding site

artículo científico publicado en 2013

Site-specific conjugation of an antibody on a gold nanoparticle surface for one-step diagnosis of prostate specific antigen with dynamic light scattering.

artículo científico publicado en 2017

Small-molecule-based affinity chromatography method for antibody purification via nucleotide binding site targeting

artículo científico publicado en 2012

Supramolecular Assemblies for Macrophage Activation in Cancer Therapy

artículo científico publicado en 2018

Synthetic Allergen Design Reveals the Significance of Moderate Affinity Epitopes in Mast Cell Degranulation ⬇️

artículo científico publicado el 21 de agosto de 2012

Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system

artículo científico publicado en 2005

The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia

artículo científico publicado en 2007

The monoclonal antibody nBT062 conjugated to cytotoxic Maytansinoids has selective cytotoxicity against CD138-positive multiple myeloma cells in vitro and in vivo

artículo científico publicado en 2009

Theoretical Analysis of Substituent Effects on Building Blocks of Conducting Polymers: 3,4'-Substituted Bithiophenes

artículo científico publicado en 1999

Threshold effects of nitric oxide-induced toxicity and cellular responses in wild-type and p53-null human lymphoblastoid cells

artículo científico publicado en 2006

p38 mitogen-activated protein kinase inhibitor LY2228820 enhances bortezomib-induced cytotoxicity and inhibits osteoclastogenesis in multiple myeloma; therapeutic implications.

artículo científico publicado en 2008

Lista de obras de

5-Azacytidine, a DNA methyltransferase inhibitor, induces ATR-mediated DNA double-strand break responses, apoptosis, and synergistic cytotoxicity with doxorubicin and bortezomib against multiple myeloma cells.

A Systematic Analysis of Peptide Linker Length and Liposomal Polyethylene Glycol Coating on Cellular Uptake of Peptide-Targeted Liposomes ⬇️

A dual-color fluorescence imaging-based system for the dissection of antiangiogenic and chemotherapeutic activity of molecules

Aggresome induction by proteasome inhibitor bortezomib and alpha-tubulin hyperacetylation by tubulin deacetylase (TDAC) inhibitor LBH589 are synergistic in myeloma cells

Antibody purification via affinity membrane chromatography method utilizing nucleotide binding site targeting with a small molecule.

BIRB 796 enhances cytotoxicity triggered by bortezomib, heat shock protein (Hsp) 90 inhibitor, and dexamethasone via inhibition of p38 mitogen-activated protein kinase/Hsp27 pathway in multiple myeloma cell lines and inhibits paracrine tumour growth

Biologic sequelae of I{kappa}B kinase (IKK) inhibition in multiple myeloma: therapeutic implications

Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma

Covalent Heterobivalent Inhibitor Design for Inhibition of IgE-Dependent Penicillin Allergy in a Murine Model

Delineation of the Chemical Pathways Underlying Nitric Oxide-Induced Homologous Recombination in Mammalian Cells

Design of a heterobivalent ligand to inhibit IgE clustering on mast cells

Design of a heterotetravalent synthetic allergen that reflects epitope heterogeneity and IgE antibody variability to study mast cell degranulation ⬇️

Designer covalent heterobivalent inhibitors prevent IgE-dependent responses to peanut allergen

Determination of Crucial Immunogenic Epitopes in Major Peanut Allergy Protein, Ara h2, via Novel Nanoallergen Platform

Didox, a ribonucleotide reductase inhibitor, induces apoptosis and inhibits DNA repair in multiple myeloma cells

Dual Carfilzomib and Doxorubicin-Loaded Liposomal Nanoparticles for Synergistic Efficacy in Multiple Myeloma

Dual-receptor targeted strategy in nanoparticle design achieves tumor cell selectivity through cooperativity

Engineering peptide-targeted liposomal nanoparticles optimized for improved selectivity for HER2-positive breast cancer cells to achieve enhanced in vivo efficacy

Enhancement of antibody selectivity via bicyclic complex formation

Erratum: In vivo and in vitro cytotoxicity of R-etodolac with dexamethasone in glucocorticoid-resistant multiple myeloma cells

Fatty acid synthase is a novel therapeutic target in multiple myeloma

Glycome and transcriptome regulation of vasculogenesis

High dose of Zoledronic acid inhibits both osteoclasts and osteoblasts in an In Vivo mouse model

High-dose zoledronic acid impacts bone remodeling with effects on osteoblastic lineage and bone mechanical properties

Identification of a moderate affinity CD22 binding peptide and in vitro optimization of peptide-targeted nanoparticles for selective uptake by CD22+ B-cell malignancies

Improved Peptide-Targeted Liposome Design Through Optimized Peptide Hydrophilicity, Ethylene Glycol Linker Length, and Peptide Density

In vivo and in vitro cytotoxicity of R-etodolac with dexamethasone in glucocorticoid-resistant multiple myeloma cells.

In vivo evaluation of CD38 and CD138 as targets for nanoparticle-based drug delivery in multiple myeloma

Inhibition of Akt induces significant downregulation of survivin and cytotoxicity in human multiple myeloma cells

Inhibition of weak-affinity epitope-IgE interactions prevents mast cell degranulation

JS-K has potent anti-angiogenic activity in vitro and inhibits tumour angiogenesis in a multiple myeloma model in vivo.

JS-K, a GST-activated nitric oxide generator, induces DNA double-strand breaks, activates DNA damage response pathways, and induces apoptosis in vitro and in vivo in human multiple myeloma cells

Ligand-targeted liposome design: challenges and fundamental considerations.

Liposomal bortezomib nanoparticles via boronic ester prodrug formulation for improved therapeutic efficacy in vivo.

Liposomal carfilzomib nanoparticles effectively target multiple myeloma cells and demonstrate enhanced efficacy in vivo.

MLN3897, a novel CCR1 inhibitor, impairs osteoclastogenesis and inhibits the interaction of multiple myeloma cells and osteoclasts.

Micellar nanoparticle formation via electrostatic interactions for delivering multinuclear platinum(II) drugs

Molecular cloning of the heparin/heparan sulfate delta 4,5 unsaturated glycuronidase from Flavobacterium heparinum, its recombinant expression in Escherichia coli, and biochemical determination of its unique substrate specificity

Nanoallergens: A multivalent platform for studying and evaluating potency of allergen epitopes in cellular degranulation

Novel etodolac analog SDX-308 (CEP-18082) induces cytotoxicity in multiple myeloma cells associated with inhibition of beta-catenin/TCF pathway.

Optimizing design parameters of a peptide targeted liposomal nanoparticle in an in vivo multiple myeloma disease model after initial evaluation in vitro

Oriented surface immobilization of antibodies at the conserved nucleotide binding site for enhanced antigen detection.

PI3K/p110{delta} is a novel therapeutic target in multiple myeloma

Photosensitive Pt(IV)-azide prodrug-loaded nanoparticles exhibit controlled drug release and enhanced efficacy in vivo

Preclinical activity of P276-00, a novel small-molecule cyclin-dependent kinase inhibitor in the therapy of multiple myeloma

Rationally engineered nanoparticles target multiple myeloma cells, overcome cell-adhesion-mediated drug resistance, and show enhanced efficacy in vivo ⬇️

SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK

Selective photocrosslinking of functional ligands to antibodies via the conserved nucleotide binding site

Site-specific conjugation of an antibody on a gold nanoparticle surface for one-step diagnosis of prostate specific antigen with dynamic light scattering.

Small-molecule-based affinity chromatography method for antibody purification via nucleotide binding site targeting

Supramolecular Assemblies for Macrophage Activation in Cancer Therapy

Synthetic Allergen Design Reveals the Significance of Moderate Affinity Epitopes in Mast Cell Degranulation ⬇️

Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system

The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia

The monoclonal antibody nBT062 conjugated to cytotoxic Maytansinoids has selective cytotoxicity against CD138-positive multiple myeloma cells in vitro and in vivo

Theoretical Analysis of Substituent Effects on Building Blocks of Conducting Polymers: 3,4'-Substituted Bithiophenes

Threshold effects of nitric oxide-induced toxicity and cellular responses in wild-type and p53-null human lymphoblastoid cells

p38 mitogen-activated protein kinase inhibitor LY2228820 enhances bortezomib-induced cytotoxicity and inhibits osteoclastogenesis in multiple myeloma; therapeutic implications.