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Characterization of the Blood-Brain Barrier Integrity and the Brain Transport of SN-38 in an Orthotopic Xenograft Rat Model of Diffuse Intrinsic Pontine Glioma

artículo científico publicado en 2020

DIPG-43. PROLONGED CONVECTION-ENHANCED DELIVERY IN THE PONS WITH SN-38 LOADED NANOPARTICLES AND IRINOTECAN.

artículo científico publicado en 2017

DIPG-49. STAT3 AS A THERAPEUTIC TARGET IN DIPG

EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

artículo científico publicado en 2017

Glucosylated nanomicelles target glucose-avid pediatric patient-derived sarcomas.

artículo científico publicado en 2018

HG-67PRECLINICAL EFFICACY OF ALK2 INHIBITORS IN ACVR1 MUTANT DIPG.

artículo científico publicado en 2016

HG-96FUNCTIONAL INTEGRITY OF THE BLOOD-BRAIN BARRIER IN H3.3K27M DIPG XENOGRAFTS.

artículo científico publicado en 2016

HG-99A PATIENT-DERIVED PAEDIATRIC HIGH GRADE GLIOMA AND DIPG CELL CULTURE PANEL RECAPITULATING THE GENOTYPIC AND PHENOTYPIC DIVERSITY OF THE DISEASE.

artículo científico publicado en 2016

Increased delivery of chemotherapy to the vitreous by inhibition of the blood-retinal barrier.

artículo científico publicado en 2017

PDTM-31. DRUG SCREENING LINKED TO MOLECULAR PROFILING IDENTIFIES NOVEL DEPENDENCIES IN PATIENT-DERIVED PRIMARY CULTURES OF PAEDIATRIC HIGH GRADE GLIOMA AND DIPG

article by Alan Mackay et al published 5 November 2018 in Neuro-Oncology

Pre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma Models

artículo científico publicado en 2017

Preclinical platform of retinoblastoma xenografts recapitulating human disease and molecular markers of dissemination.

artículo científico publicado en 2016

Targeted drug distribution in tumor extracellular fluid of GD2-expressing neuroblastoma patient-derived xenografts using SN-38-loaded nanoparticles conjugated to the monoclonal antibody 3F8.

artículo científico publicado en 2017

Therapeutic targeting of the RB1 pathway in retinoblastoma with the oncolytic adenovirus VCN-01

artículo científico publicado en 2019

Treatment-driven selection of chemoresistant Ewing sarcoma tumors with limited drug distribution

scientific article published on 01 June 2020

WNT-activated embryonal tumors of the pineal region: ectopic medulloblastomas or a novel pineoblastoma subgroup?

artículo científico publicado en 2020

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