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2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease

scientific article published on 30 April 2019

Application of Q2MM to predictions in stereoselective synthesis

scholarly article by Anthony R Rosales et al published 24 July 2018 in Chemical Communications

Chemistry. Striking a balance to control stereochemistry

scientific article published on 01 September 2011

Conformational and SAR analysis of NAALADase and PSMA inhibitors

artículo científico publicado en 2003

Design and synthesis of a crosslinker for studying intracellular steroid trafficking pathways

artículo científico publicado en 2015

Design, Synthesis, and Evaluation of a Luminescent Cholesterol Mimic

artículo científico publicado en 2020

Development of a Q2MM Force Field for the Asymmetric Rhodium Catalyzed Hydrogenation of Enamides

artículo científico publicado en 2008

Development of carbamate-tethered coumarins as phototriggers for caged nicotinamide

artículo científico publicado en 2013

Diastereoselectivity in Lewis-acid-catalyzed Mukaiyama aldol reactions: a DFT study

artículo científico publicado en 2012

Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts

artículo científico publicado el 21 de marzo de 2011

Identification of novel inhibitors for a low molecular weight protein tyrosine phosphatase via virtual screening

artículo científico publicado en 2010

Inhibition of Histone Deacetylases 1, 2, and 3 Enhances Clearance of Cholesterol Accumulation in Niemann-Pick C1 Fibroblasts

artículo científico publicado en 2021

Inhibition of histone deacetylases: a pharmacological approach to the treatment of non-cancer disorders.

scientific article published on January 2009

Inhibition studies with rationally designed inhibitors of the human low molecular weight protein tyrosine phosphatase

artículo científico publicado en 2004

Intramolecular hydroamination of aminoalkynes with silver-phenanthroline catalysts

artículo científico publicado en 2008

Investigation of N-aryl-3-alkylidenepyrrolinones as potential Niemann-Pick type C disease therapeutics

artículo científico publicado en 2009

Mild and efficient desymmetrization of diynes via hydroamination: application to the synthesis of (+/-)-monomorine I.

artículo científico publicado en 2010

Ni-Catalyzed Alkenylation of Ketone Enolates under Mild Conditions: Catalyst Identification and Optimization

artículo científico publicado en 2015

On the function of the 14 A long internal cavity of histone deacetylase-like protein: implications for the design of histone deacetylase inhibitors

artículo científico publicado en 2004

Palladium-catalyzed alkenylation of ketone enolates under mild conditions

artículo científico publicado en 2014

Prediction of enantioselectivity in rhodium catalyzed hydrogenations

artículo científico publicado en 2009

QSAR studies of PC-3 cell line inhibition activity of TSA and SAHA-like hydroxamic acids

artículo científico publicado en 2004

Quantitative comparison of the efficacy of various compounds in lowering intracellular cholesterol levels in Niemann-Pick type C fibroblasts

artículo científico publicado en 2012

Single-Flask Multicomponent Palladium-Catalyzed α,γ-Coupling of Ketone Enolates: Facile Preparation of Complex Carbon Scaffolds.

artículo científico publicado en 2015

Single-Flask Multicomponent Synthesis of Highly Substituted α-Pyrones via a Sequential Enolate Arylation and Alkenylation Strategy

artículo científico publicado en 2016

Stereoselectivity in (Acyloxy)borane-Catalyzed Mukaiyama Aldol Reactions

artículo científico publicado en 2016

Stereoselectivity in Asymmetric Catalysis: The Case of Ruthenium-Catalyzed Ketone Hydrogenation

artículo científico publicado en 2014

Syntheses of conformationally constricted molecules as potential NAALADase/PSMA inhibitors

artículo científico publicado en 2004

Synthesis and photochemical behavior of coumarin-caged cholesterol.

artículo científico publicado en 2013

Synthesis of 4-methyldienoates using a vinylogous Horner-Wadsworth-Emmons reagent. Application to the synthesis of trichostatic acid

artículo científico publicado en 2010

Synthesis of primary aryl amines through a copper-assisted aromatic substitution reaction with sodium azide

artículo científico publicado en 2010

Synthesis, photophysical, photochemical, and computational studies of coumarin-labeled nicotinamide derivatives

artículo científico publicado en 2012

Synthesis, structure, and metal complexation behavior of a new type of functionalized chiral phenanthroline derivative

artículo científico publicado en 2008

Thiadiazole carbamates: potent inhibitors of lysosomal acid lipase and potential Niemann-Pick type C disease therapeutics

artículo científico publicado en 2010

Toward selective histone deacetylase inhibitor design: homology modeling, docking studies, and molecular dynamics simulations of human class I histone deacetylases

artículo científico

Transition State Force Field for the Asymmetric Redox Relay Heck Reaction

scientific article published on 05 April 2020

Treatment of Niemann--pick type C disease by histone deacetylase inhibitors.

artículo científico publicado en 2013

Zinc binding in HDAC inhibitors: a DFT study

scientific article published on 19 June 2007

pHP-Tethered N-Acyl Carbamate: A Photocage for Nicotinamide.

artículo científico publicado en 2018