Lista de obras -

A G protein-coupled receptor at work: the rhodopsin model.

artículo científico publicado en 2009

A ligand channel through the G protein coupled receptor opsin

artículo científico publicado en 2009

A photo-cross-linking strategy to map sites of protein-protein interactions

artículo científico publicado en 2010

An approach to quality management in structural biology: biophysical selection of proteins for successful crystallization.

artículo científico publicado en 2008

Arrestin and its splice variant Arr1-370A (p44). Mechanism and biological role of their interaction with rhodopsin

artículo científico publicado en 2002

Arrestin-Rhodopsin Binding Stoichiometry in Isolated Rod Outer Segment Membranes Depends on the Percentage of Activated Receptors ⬇️

artículo científico publicado el 17 de diciembre de 2010

Asymmetric properties of rod cGMP Phosphodiesterase 6 (PDE6): structural and functional analysis.

artículo científico publicado en 2015

Biochemical and physiological properties of rhodopsin regenerated with 11-cis-6-ring- and 7-ring-retinals

artículo científico publicado en 2002

Building functional modules from molecular interactions

artículo científico publicado en 2006

Calcium-dependent assembly of centrin-G-protein complex in photoreceptor cells

artículo científico publicado en 2002

Conformational Dynamics During GPCR - G Protein Coupling

article published in 2014

Conformational equilibria of light-activated rhodopsin in nanodiscs

artículo científico publicado en 2017

Conserved Tyr223(5.58) plays different roles in the activation and G-protein interaction of rhodopsin.

artículo científico publicado en 2011

Constraints on the conformation of the cytoplasmic face of dark-adapted and light-excited rhodopsin inferred from antirhodopsin antibody imprints.

artículo científico publicado en 2003

Crystal structure of a common GPCR-binding interface for G protein and arrestin

artículo científico publicado en 2014

Crystal structure of metarhodopsin II

artículo científico publicado en 2011

Crystal structure of opsin in its G-protein-interacting conformation

artículo científico publicado en 2008

Crystal structure of pre-activated arrestin p44

artículo científico publicado en 2013

Crystal structure of the ligand-free G-protein-coupled receptor opsin

artículo científico publicado en 2008

Crystallization and preliminary X-ray studies of mouse centrin1

artículo científico publicado en 2005

Deactivation and proton transfer in light-induced metarhodopsin II/metarhodopsin III conversion: a time-resolved fourier transform infrared spectroscopic study

artículo científico publicado en 2007

Differential expression and interaction with the visual G-protein transducin of centrin isoforms in mammalian photoreceptor cells

scientific journal article

Effect of channel mutations on the uptake and release of the retinal ligand in opsin.

artículo científico publicado en 2012

Effect of cholesterol and surfactant protein B on the viscosity of phospholipid mixtures

artículo científico publicado en 2002

Erratum: Distinct loops in arrestin differentially regulate ligand binding within the GPCR opsin.

artículo científico publicado en 2012

Explicit spatiotemporal simulation of receptor-G protein coupling in rod cell disk membranes

artículo científico publicado en 2014

Formation and decay of the arrestin·rhodopsin complex in native disc membranes

artículo científico publicado en 2015

Féry Infrared Spectrometer for Single-Shot Analysis of Protein Dynamics

scientific article published on 02 December 2019

High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation

artículo científico publicado en 2008

Insights into functional aspects of centrins from the structure of N-terminally extended mouse centrin 1.

artículo científico publicado en 2006

Interaction with transducin depletes metarhodopsin III: a regulated retinal storage in visual signal transduction?

artículo científico publicado en 2004

It takes two transducins to activate the cGMP-phosphodiesterase 6 in retinal rods

artículo científico publicado en 2018

Ligand channeling within a G-protein-coupled receptor. The entry and exit of retinals in native opsin

artículo científico publicado en 2003

Monomeric G protein-coupled receptor rhodopsin in solution activates its G protein transducin at the diffusion limit

artículo científico publicado en 2007

N-terminal and C-terminal domains of arrestin both contribute in binding to rhodopsin

artículo científico

Not just signal shutoff: the protective role of arrestin-1 in rod cells

artículo científico publicado en 2014

Opsin, a structural model for olfactory receptors?

artículo científico publicado en 2013

Partial agonism in a G Protein-coupled receptor: role of the retinal ring structure in rhodopsin activation

artículo científico publicado en 2005

Phototransduction gain at the G-protein, transducin, and effector protein, phosphodiesterase-6, stages in retinal rods

artículo científico publicado en 2019

Position of transmembrane helix 6 determines receptor G protein coupling specificity

artículo científico publicado en 2014

Preliminary X-ray characterization of the ribonuclease P (C5 protein) from Escherichia coli: expression, crystallization and cryoconditions

artículo científico publicado en 2003

Response to comment "Transient complexes between dark rhodopsin and transducin: circumstantial evidence or physiological necessity?" by D. Dell'Orco and K.-W. Koch

artículo científico publicado en 2015

Retinol dehydrogenase (RDH12) protects photoreceptors from light-induced degeneration in mice

artículo científico publicado en 2006

Rhodopsin and 9-demethyl-retinal analog: effect of a partial agonist on displacement of transmembrane helix 6 in class A G protein-coupled receptors

artículo científico publicado en 2007

Rhodopsin and 9-demethyl-retinal analog: effect of a partial agonist on displacement of transmembrane helix 6 in class A G protein-coupled receptors. VOLUME 283 (2008) PAGES 4967-4974.

artículo científico publicado en 2008

Rhodopsin-transducin coupling: role of the Galpha C-terminus in nucleotide exchange catalysis.

artículo científico publicado en 2006

Role of Structural Dynamics at the Receptor G Protein Interface for Signal Transduction

artículo científico publicado en 2015

Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation

artículo científico publicado en 2003

Secondary binding sites of retinoids in opsin: characterization and role in regeneration ⬇️

artículo científico publicado el 1 de diciembre de 2003

Sequence of interactions in receptor-G protein coupling.

artículo científico publicado en 2004

Sequence of late molecular events in the activation of rhodopsin

artículo científico publicado en 2007

Signal transduction in the visual cascade involves specific lipid-protein interactions

artículo científico publicado en 2003

Signal transfer from GPCRs to G proteins: role of the G alpha N-terminal region in rhodopsin-transducin coupling.

artículo científico publicado en 2006

Signaling states of rhodopsin. Formation of the storage form, metarhodopsin III, from active metarhodopsin II

artículo científico publicado en 2002

Spatial and Temporal Aspects of Signaling by G-Protein-Coupled Receptors

artículo científico publicado en 2015

Structural and kinetic modeling of an activating helix switch in the rhodopsin-transducin interface

scholarly article

Structure-based biophysical analysis of the interaction of rhodopsin with G protein and arrestin

artículo científico publicado en 2015

The Activation Pathway of Human Rhodopsin in Comparison to Bovine Rhodopsin

artículo científico publicado en 2015

The arrestin-1 finger loop interacts with two distinct conformations of active rhodopsin

artículo científico publicado en 2018

Transition of rhodopsin into the active metarhodopsin II state opens a new light-induced pathway linked to Schiff base isomerization

artículo científico publicado en 2004

Viruses as vesicular carriers of the viral genome: a functional module perspective.

scientific article published on 25 January 2010

Lista de obras de

A G protein-coupled receptor at work: the rhodopsin model.

A ligand channel through the G protein coupled receptor opsin

A photo-cross-linking strategy to map sites of protein-protein interactions

An approach to quality management in structural biology: biophysical selection of proteins for successful crystallization.

Arrestin and its splice variant Arr1-370A (p44). Mechanism and biological role of their interaction with rhodopsin

Arrestin-Rhodopsin Binding Stoichiometry in Isolated Rod Outer Segment Membranes Depends on the Percentage of Activated Receptors ⬇️

Asymmetric properties of rod cGMP Phosphodiesterase 6 (PDE6): structural and functional analysis.

Biochemical and physiological properties of rhodopsin regenerated with 11-cis-6-ring- and 7-ring-retinals

Building functional modules from molecular interactions

Calcium-dependent assembly of centrin-G-protein complex in photoreceptor cells

Conformational Dynamics During GPCR - G Protein Coupling

Conformational equilibria of light-activated rhodopsin in nanodiscs

Conserved Tyr223(5.58) plays different roles in the activation and G-protein interaction of rhodopsin.

Constraints on the conformation of the cytoplasmic face of dark-adapted and light-excited rhodopsin inferred from antirhodopsin antibody imprints.

Crystal structure of a common GPCR-binding interface for G protein and arrestin

Crystal structure of metarhodopsin II

Crystal structure of opsin in its G-protein-interacting conformation

Crystal structure of pre-activated arrestin p44

Crystal structure of the ligand-free G-protein-coupled receptor opsin

Crystallization and preliminary X-ray studies of mouse centrin1

Deactivation and proton transfer in light-induced metarhodopsin II/metarhodopsin III conversion: a time-resolved fourier transform infrared spectroscopic study

Differential expression and interaction with the visual G-protein transducin of centrin isoforms in mammalian photoreceptor cells

Effect of channel mutations on the uptake and release of the retinal ligand in opsin.

Effect of cholesterol and surfactant protein B on the viscosity of phospholipid mixtures

Erratum: Distinct loops in arrestin differentially regulate ligand binding within the GPCR opsin.

Explicit spatiotemporal simulation of receptor-G protein coupling in rod cell disk membranes

Formation and decay of the arrestin·rhodopsin complex in native disc membranes

Féry Infrared Spectrometer for Single-Shot Analysis of Protein Dynamics

High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation

Insights into functional aspects of centrins from the structure of N-terminally extended mouse centrin 1.

Interaction with transducin depletes metarhodopsin III: a regulated retinal storage in visual signal transduction?

It takes two transducins to activate the cGMP-phosphodiesterase 6 in retinal rods

Ligand channeling within a G-protein-coupled receptor. The entry and exit of retinals in native opsin

Monomeric G protein-coupled receptor rhodopsin in solution activates its G protein transducin at the diffusion limit

N-terminal and C-terminal domains of arrestin both contribute in binding to rhodopsin

Not just signal shutoff: the protective role of arrestin-1 in rod cells

Opsin, a structural model for olfactory receptors?

Partial agonism in a G Protein-coupled receptor: role of the retinal ring structure in rhodopsin activation

Phototransduction gain at the G-protein, transducin, and effector protein, phosphodiesterase-6, stages in retinal rods

Position of transmembrane helix 6 determines receptor G protein coupling specificity

Preliminary X-ray characterization of the ribonuclease P (C5 protein) from Escherichia coli: expression, crystallization and cryoconditions

Response to comment "Transient complexes between dark rhodopsin and transducin: circumstantial evidence or physiological necessity?" by D. Dell'Orco and K.-W. Koch

Retinol dehydrogenase (RDH12) protects photoreceptors from light-induced degeneration in mice

Rhodopsin and 9-demethyl-retinal analog: effect of a partial agonist on displacement of transmembrane helix 6 in class A G protein-coupled receptors

Rhodopsin and 9-demethyl-retinal analog: effect of a partial agonist on displacement of transmembrane helix 6 in class A G protein-coupled receptors. VOLUME 283 (2008) PAGES 4967-4974.

Rhodopsin-transducin coupling: role of the Galpha C-terminus in nucleotide exchange catalysis.

Role of Structural Dynamics at the Receptor G Protein Interface for Signal Transduction

Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation

Secondary binding sites of retinoids in opsin: characterization and role in regeneration ⬇️

Sequence of interactions in receptor-G protein coupling.

Sequence of late molecular events in the activation of rhodopsin

Signal transduction in the visual cascade involves specific lipid-protein interactions

Signal transfer from GPCRs to G proteins: role of the G alpha N-terminal region in rhodopsin-transducin coupling.

Signaling states of rhodopsin. Formation of the storage form, metarhodopsin III, from active metarhodopsin II

Spatial and Temporal Aspects of Signaling by G-Protein-Coupled Receptors

Structural and kinetic modeling of an activating helix switch in the rhodopsin-transducin interface

Structure-based biophysical analysis of the interaction of rhodopsin with G protein and arrestin

The Activation Pathway of Human Rhodopsin in Comparison to Bovine Rhodopsin

The arrestin-1 finger loop interacts with two distinct conformations of active rhodopsin

Transition of rhodopsin into the active metarhodopsin II state opens a new light-induced pathway linked to Schiff base isomerization

Viruses as vesicular carriers of the viral genome: a functional module perspective.