Lista de obras -

A liposomal RNA vaccine inducing neoantigen-specific CD4+ T cells augments the antitumor activity of local radiotherapy in mice

scientific article published on 22 June 2020

A non-functional neoepitope specific CD8+ T-cell response induced by tumor derived antigen exposure in vivo

scientific article published on 24 December 2018

A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis

artículo científico publicado en 2021

Actively personalized vaccination trial for newly diagnosed glioblastoma

scientific article published on 19 December 2018

An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma

artículo científico publicado en 2020

Antitumor vaccination with synthetic mRNA: strategies for in vitro and in vivo preclinical studies.

artículo científico

CIMT 2013: advancing targeted therapies--report on the 11th Annual Meeting of the Association for Cancer Immunotherapy, May 14-16 2013, Mainz, Germany ⬇️

artículo científico publicado el 22 de julio de 2013

CIMT 2014: Next waves in cancer immunotherapy--report on the 12th annual meeting of the Association for Cancer Immunotherapy: May 6–8 2014, Mainz, Germany

artículo científico publicado en 2014

CIMT 2015: The right patient for the right therapy - Report on the 13th annual meeting of the Association for Cancer Immunotherapy

artículo científico publicado en 2015

CIMT 2016: Mechanisms of efficacy in cancer immunotherapy - Report on the 14th Annual Meeting of the Association for Cancer Immunotherapy May 10-12 2016, Mainz, Germany.

artículo científico publicado en 2016

Cancer classification using the Immunoscore: a worldwide task force

artículo científico publicado en 2012

Confidence-based somatic mutation evaluation and prioritization

artículo científico publicado en 2012

Current Developments in Actively Personalized Cancer Vaccination with a Focus on RNA as the Drug Format

artículo científico

Determinants of intracellular RNA pharmacokinetics: Implications for RNA-based immunotherapeutics

article

Dexamethasone premedication suppresses vaccine-induced immune responses against cancer

scientific article published on 13 May 2020

Discovery and Subtyping of Neo-Epitope Specific T-Cell Responses for Cancer Immunotherapy: Addressing the Mutanome.

artículo científico publicado en 2017

Erratum: Mutant MHC class II epitopes drive therapeutic immune responses to cancer

artículo científico publicado en 2015

Exploiting the mutanome for tumor vaccination.

artículo científico publicado en 2012

FLT3 Ligand as a Molecular Adjuvant for Naked RNA Vaccines

artículo científico publicado en 2016

FLT3 ligand enhances the cancer therapeutic potency of naked RNA vaccines.

artículo científico publicado en 2011

Functional TCR retrieval from single antigen-specific human T cells reveals multiple novel epitopes.

artículo científico publicado en 2014

Generation of TCR-engineered T cells and their use to control the performance of T cell assays

artículo científico publicado en 2015

HPV16 RNA-LPX vaccine mediates complete regression of aggressively growing HPV-positive mouse tumors and establishes protective T cell memory

artículo científico publicado en 2019

Highly specific auto-antibodies against claudin-18 isoform 2 induced by a chimeric HBcAg virus-like particle vaccine kill tumor cells and inhibit the growth of lung metastases.

artículo científico publicado en 2011

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma

artículo científico publicado en 2018

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma

artículo científico publicado en 2019

Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma

artículo científico publicado en 2014

Improvement of in vivo expression of genes delivered by self-amplifying RNA using Vaccinia Virus immune evasion proteins

artículo científico publicado en 2017

Increased Antigen Presentation Efficiency by Coupling Antigens to MHC Class I Trafficking Signals

artículo científico publicado en 2008

Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity.

artículo científico publicado en 2010

Intravenous delivery of the toll-like receptor 7 agonist SC1 confers tumor control by inducing a CD8+ T cell response

artículo científico publicado en 2019

Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models

artículo científico publicado en 2021

Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells.

artículo científico publicado en 2006

Mutanome directed cancer immunotherapy

artículo científico

Mutant MHC class II epitopes drive therapeutic immune responses to cancer

artículo científico publicado en 2015

Mutated tumor alleles are expressed according to their DNA frequency

artículo científico publicado en 2014

Past, present and future of immunology in Mainz

artículo científico publicado en 2016

Personalized Neo-Epitope Vaccines for Cancer Treatment

scientific article published on 01 January 2020

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

artículo científico publicado en 2017

Publisher Correction: Actively personalized vaccination trial for newly diagnosed glioblastoma

scientific article published on 01 February 2019

Simultaneous ex vivo quantification of antigen-specific CD4+ and CD8+ T cell responses using in vitro transcribed RNA

article

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

artículo científico publicado en 2016

Targeting the Heterogeneity of Cancer with Individualized Neoepitope Vaccines.

artículo científico publicado en 2016

Targeting the tumor mutanome for personalized vaccination therapy

artículo científico publicado en 2012

The European Regulatory Environment of RNA-Based Vaccines

artículo científico publicado en 2017

The regulatory landscape for actively personalized cancer immunotherapies

article published in 2013

Tumor vaccination using messenger RNA: prospects of a future therapy

artículo científico publicado en 2011

Uptake of synthetic naked RNA by skin-resident dendritic cells via macropinocytosis allows antigen expression and induction of T-cell responses in mice

artículo científico publicado en 2016

Withdrawal: Identification of tumor antigens among the HLA peptidomes of glioblastoma tumors and plasma

artículo científico publicado en 2019

mRNA: A Versatile Molecule for Cancer Vaccines.

artículo científico publicado en 2016

mTOR inhibition improves antitumor effects of vaccination with antigen-encoding RNA.

artículo científico publicado en 2013

Lista de obras de

A liposomal RNA vaccine inducing neoantigen-specific CD4+ T cells augments the antitumor activity of local radiotherapy in mice

A non-functional neoepitope specific CD8+ T-cell response induced by tumor derived antigen exposure in vivo

A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis

Actively personalized vaccination trial for newly diagnosed glioblastoma

An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma

Antitumor vaccination with synthetic mRNA: strategies for in vitro and in vivo preclinical studies.

CIMT 2013: advancing targeted therapies--report on the 11th Annual Meeting of the Association for Cancer Immunotherapy, May 14-16 2013, Mainz, Germany ⬇️

CIMT 2014: Next waves in cancer immunotherapy--report on the 12th annual meeting of the Association for Cancer Immunotherapy: May 6–8 2014, Mainz, Germany

CIMT 2015: The right patient for the right therapy - Report on the 13th annual meeting of the Association for Cancer Immunotherapy

CIMT 2016: Mechanisms of efficacy in cancer immunotherapy - Report on the 14th Annual Meeting of the Association for Cancer Immunotherapy May 10-12 2016, Mainz, Germany.

Cancer classification using the Immunoscore: a worldwide task force

Confidence-based somatic mutation evaluation and prioritization

Current Developments in Actively Personalized Cancer Vaccination with a Focus on RNA as the Drug Format

Determinants of intracellular RNA pharmacokinetics: Implications for RNA-based immunotherapeutics

Dexamethasone premedication suppresses vaccine-induced immune responses against cancer

Discovery and Subtyping of Neo-Epitope Specific T-Cell Responses for Cancer Immunotherapy: Addressing the Mutanome.

Erratum: Mutant MHC class II epitopes drive therapeutic immune responses to cancer

Exploiting the mutanome for tumor vaccination.

FLT3 Ligand as a Molecular Adjuvant for Naked RNA Vaccines

FLT3 ligand enhances the cancer therapeutic potency of naked RNA vaccines.

Functional TCR retrieval from single antigen-specific human T cells reveals multiple novel epitopes.

Generation of TCR-engineered T cells and their use to control the performance of T cell assays

HPV16 RNA-LPX vaccine mediates complete regression of aggressively growing HPV-positive mouse tumors and establishes protective T cell memory

Highly specific auto-antibodies against claudin-18 isoform 2 induced by a chimeric HBcAg virus-like particle vaccine kill tumor cells and inhibit the growth of lung metastases.

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma

Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma

Improvement of in vivo expression of genes delivered by self-amplifying RNA using Vaccinia Virus immune evasion proteins

Increased Antigen Presentation Efficiency by Coupling Antigens to MHC Class I Trafficking Signals

Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity.

Intravenous delivery of the toll-like receptor 7 agonist SC1 confers tumor control by inducing a CD8+ T cell response

Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models

Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells.

Mutanome directed cancer immunotherapy

Mutant MHC class II epitopes drive therapeutic immune responses to cancer

Mutated tumor alleles are expressed according to their DNA frequency

Past, present and future of immunology in Mainz

Personalized Neo-Epitope Vaccines for Cancer Treatment

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

Publisher Correction: Actively personalized vaccination trial for newly diagnosed glioblastoma

Simultaneous ex vivo quantification of antigen-specific CD4+ and CD8+ T cell responses using in vitro transcribed RNA

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

Targeting the Heterogeneity of Cancer with Individualized Neoepitope Vaccines.

Targeting the tumor mutanome for personalized vaccination therapy

The European Regulatory Environment of RNA-Based Vaccines

The regulatory landscape for actively personalized cancer immunotherapies

Tumor vaccination using messenger RNA: prospects of a future therapy

Uptake of synthetic naked RNA by skin-resident dendritic cells via macropinocytosis allows antigen expression and induction of T-cell responses in mice

Withdrawal: Identification of tumor antigens among the HLA peptidomes of glioblastoma tumors and plasma

mRNA: A Versatile Molecule for Cancer Vaccines.

mTOR inhibition improves antitumor effects of vaccination with antigen-encoding RNA.