Lista de obras -

A chimeric pre-ubiquitinated EGF receptor is constitutively endocytosed in a clathrin-dependent, but kinase-independent manner

artículo científico publicado en 2011

Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits

artículo científico publicado en 2006

Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor

scientific article published on 08 June 2006

CD7 expression by CD34+ cells in CML patients, of prognostic significance?

artículo científico publicado en 2003

CIN85 regulates ubiquitination and degradative endosomal sorting of the EGF receptor

artículo científico publicado en 2011

Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits

artículo científico publicado en 2004

Cetuximab in combination with anti-human IgG antibodies efficiently down-regulates the EGF receptor by macropinocytosis.

artículo científico publicado en 2012

Cholesterol is important in control of EGF receptor kinase activity but EGF receptors are not concentrated in caveolae

artículo científico publicado en 2002

Differential Roles of Grb2 and AP‐2 in p38MAPK‐ and EGF‐Induced EGFR Internalization ⬇️

artículo científico publicado el 17 de enero de 2012

Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation

artículo científico publicado en 2004

Dysregulation of Ack1 inhibits down-regulation of the EGF receptor

artículo científico publicado en 2008

EGF-induced activation of the EGF receptor does not trigger mobilization of caveolae

artículo científico publicado en 2006

Epidermal growth factor receptor and cancer: control of oncogenic signalling by endocytosis

artículo científico publicado en 2008

Epsin 1 is involved in recruitment of ubiquitinated EGF receptors into clathrin-coated pits

artículo científico publicado en 2008

Expression of epidermal growth factor receptor or ErbB3 facilitates geldanamycin-induced down-regulation of ErbB2.

artículo científico publicado en 2009

Geldanamycin-induced down-regulation of ErbB2 from the plasma membrane is clathrin dependent but proteasomal activity independent

artículo científico publicado en 2008

Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2.

artículo científico publicado en 2005

Internalization and intracellular sorting of the EGF receptor: a model for understanding the mechanisms of receptor trafficking

artículo científico publicado en 2009

Nimotuzumab and cetuximab block ligand-independent EGF receptor signaling efficiently at different concentrations.

artículo científico publicado en 2011

Pertuzumab Increases 17-AAG-Induced Degradation of ErbB2, and This Effect Is Further Increased by Combining Pertuzumab with Trastuzumab

artículo científico publicado en 2012

Pertuzumab counteracts the inhibitory effect of ErbB2 on degradation of ErbB3.

artículo científico publicado en 2013

Pertuzumab increases epidermal growth factor receptor down-regulation by counteracting epidermal growth factor receptor-ErbB2 heterodimerization

artículo científico publicado en 2009

Phosphorylation of Hrs downstream of the epidermal growth factor receptor

artículo científico publicado en 2002

Preubiquitinated chimeric ErbB2 is constitutively endocytosed and subsequently degraded in lysosomes.

artículo científico publicado en 2012

The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis

artículo científico publicado en 2007

The inhibitory effect of ErbB2 on epidermal growth factor-induced formation of clathrin-coated pits correlates with retention of epidermal growth factor receptor-ErbB2 oligomeric complexes at the plasma membrane

artículo científico publicado en 2005

The oncoprotein ErbB3 is endocytosed in the absence of added ligand in a clathrin-dependent manner

artículo científico publicado en 2012

Ubiquitin binding in endocytosis--how tight should it be and where does it happen?

artículo científico publicado en 2006

Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies

artículo científico publicado en 2002

Lista de obras de

A chimeric pre-ubiquitinated EGF receptor is constitutively endocytosed in a clathrin-dependent, but kinase-independent manner

Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits

Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor

CD7 expression by CD34+ cells in CML patients, of prognostic significance?

CIN85 regulates ubiquitination and degradative endosomal sorting of the EGF receptor

Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits

Cetuximab in combination with anti-human IgG antibodies efficiently down-regulates the EGF receptor by macropinocytosis.

Cholesterol is important in control of EGF receptor kinase activity but EGF receptors are not concentrated in caveolae

Differential Roles of Grb2 and AP‐2 in p38MAPK‐ and EGF‐Induced EGFR Internalization ⬇️

Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation

Dysregulation of Ack1 inhibits down-regulation of the EGF receptor

EGF-induced activation of the EGF receptor does not trigger mobilization of caveolae

Epidermal growth factor receptor and cancer: control of oncogenic signalling by endocytosis

Epsin 1 is involved in recruitment of ubiquitinated EGF receptors into clathrin-coated pits

Expression of epidermal growth factor receptor or ErbB3 facilitates geldanamycin-induced down-regulation of ErbB2.

Geldanamycin-induced down-regulation of ErbB2 from the plasma membrane is clathrin dependent but proteasomal activity independent

Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2.

Internalization and intracellular sorting of the EGF receptor: a model for understanding the mechanisms of receptor trafficking

Nimotuzumab and cetuximab block ligand-independent EGF receptor signaling efficiently at different concentrations.

Pertuzumab Increases 17-AAG-Induced Degradation of ErbB2, and This Effect Is Further Increased by Combining Pertuzumab with Trastuzumab

Pertuzumab counteracts the inhibitory effect of ErbB2 on degradation of ErbB3.

Pertuzumab increases epidermal growth factor receptor down-regulation by counteracting epidermal growth factor receptor-ErbB2 heterodimerization

Phosphorylation of Hrs downstream of the epidermal growth factor receptor

Preubiquitinated chimeric ErbB2 is constitutively endocytosed and subsequently degraded in lysosomes.

The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis

The inhibitory effect of ErbB2 on epidermal growth factor-induced formation of clathrin-coated pits correlates with retention of epidermal growth factor receptor-ErbB2 oligomeric complexes at the plasma membrane

The oncoprotein ErbB3 is endocytosed in the absence of added ligand in a clathrin-dependent manner

Ubiquitin binding in endocytosis--how tight should it be and where does it happen?

Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies