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(1→3)-β-d-Glucan in Cerebrospinal Fluid as a Biomarker for Candida and Aspergillus Infections of the Central Nervous System in Pediatric Patients

artículo científico publicado en 2015

2381. Ceftolozane/Tazobactam in the Treatment of Experimental Pseudomonas aeruginosa Pneumonia in Persistently Neutropenic Rabbits: Impact on Strains With Genetically Defined Resistance

2600. Mannose-Binding Lectin Polymorphisms are Important Modulating Factors in Community- and Hospital-Acquired Pneumonia Caused by Legionella spp

A Real-Time PCR Assay for Rapid Detection and Quantification of Exserohilum rostratum, a Causative Pathogen of Fungal Meningitis Associated with Injection of Contaminated Methylprednisolone

artículo científico publicado el 9 de enero de 2013

Amphotericin B Penetrates into the Central Nervous System Through Focal Disruption of the Blood Brain Barrier in Experimental Hematogenous Candida Meningoencephalitis

artículo científico publicado en 2019

Amphotericin B formulations exert additive antifungal activity in combination with pulmonary alveolar macrophages and polymorphonuclear leukocytes against Aspergillus fumigatus

artículo científico publicado en 2002

Anidulafungin for neonatal hematogenous Candida meningoencephalitis: identification of candidate regimens for humans using a translational pharmacological approach.

artículo científico publicado en 2011

Antifungal activity of gepinacin-scaffold GPI anchor biosynthesis inhibitors with improved metabolic stability

artículo científico publicado en 2020

Antifungal efficacy of caspofungin (MK-0991) in experimental pulmonary aspergillosis in persistently neutropenic rabbits: pharmacokinetics, drug disposition, and relationship to galactomannan antigenemia

artículo científico publicado en 2002

Antifungal efficacy of isavuconazole and liposomal amphotericin B in a rabbit model of Exserohilum rostratum meningoencephalitis: A preclinical paradigm for management of CNS phaeohyphomycosis

artículo científico publicado en 2020

Automated and manual methods of DNA extraction for Aspergillus fumigatus and Rhizopus oryzae analyzed by quantitative real-time PCR

artículo científico publicado en 2008

Candida Arthritis: Analysis of 112 Pediatric and Adult Cases

artículo científico publicado en 2015

Ceftolozane-Tazobactam in the Treatment of Experimental Pseudomonas aeruginosa Pneumonia in Persistently Neutropenic Rabbits: Impact on Strains with Genetically Defined Mechanisms of Resistance

scientific article published on 23 August 2019

Cerebrospinal fluid and plasma (1-->3)-beta-D-glucan as surrogate markers for detection and monitoring of therapeutic response in experimental hematogenous Candida meningoencephalitis

artículo científico publicado en 2008

Characterization and comparison of galactomannan enzyme immunoassay and quantitative real-time PCR assay for detection of Aspergillus fumigatus in bronchoalveolar lavage fluid from experimental invasive pulmonary aspergillosis

artículo científico publicado en 2006

Clinical Pharmacokinetics and Pharmacodynamics of Isavuconazole

artículo científico publicado en 2018

Combination Therapy with Ibrexafungerp (formerly SCY-078), a First-in-Class Triterpenoid Inhibitor of (1→3)-β-D-Glucan Synthesis, and Isavuconazole for Treatment of Experimental Invasive Pulmonary Aspergillosis

scientific article published on 16 March 2020

Combination Therapy with Isavuconazole and Micafungin for Treatment of Experimental Invasive Pulmonary Aspergillosis

artículo científico publicado en 2017

Combination therapy in treatment of experimental pulmonary aspergillosis: in vitro and in vivo correlations of the concentration- and dose- dependent interactions between anidulafungin and voriconazole by Bliss independence drug interaction analysis

artículo científico publicado en 2009

Combination therapy in treatment of experimental pulmonary aspergillosis: synergistic interaction between an antifungal triazole and an echinocandin

artículo científico publicado en 2003

Comparative antifungal activities and plasma pharmacokinetics of micafungin (FK463) against disseminated candidiasis and invasive pulmonary aspergillosis in persistently neutropenic rabbits

artículo científico publicado en 2002

Comparative drug disposition, urinary pharmacokinetics, and renal effects of multilamellar liposomal nystatin and amphotericin B deoxycholate in rabbits

artículo científico publicado en 2003

Compartmental pharmacokinetics and tissue distribution of the antifungal triazole ravuconazole following intravenous administration of its di-lysine phosphoester prodrug (BMS-379224) in rabbits

artículo científico publicado en 2005

Compartmentalized intrapulmonary pharmacokinetics of amphotericin B and its lipid formulations

artículo científico publicado en 2006

Deoxycholate amphotericin B and amphotericin B lipid complex exert additive antifungal activity in combination with pulmonary alveolar macrophages against Fusarium solani

artículo científico publicado en 2006

Detection of a molecular biomarker for zygomycetes by quantitative PCR assays of plasma, bronchoalveolar lavage, and lung tissue in a rabbit model of experimental pulmonary zygomycosis

artículo científico publicado en 2008

Detection of galactomannan antigenemia in patients receiving piperacillin-tazobactam and correlations between in vitro, in vivo, and clinical properties of the drug-antigen interaction

artículo científico publicado en 2004

Development and validation of a quantitative real-time PCR assay using fluorescence resonance energy transfer technology for detection of Aspergillus fumigatus in experimental invasive pulmonary aspergillosis

artículo científico publicado en 2003

Diagnostic imaging of experimental invasive pulmonary aspergillosis

artículo científico publicado en 2009

Early serum (1→3)‐β‐D‐glucan levels in patients with burn injury

artículo científico publicado el 19 de julio de 2011

Echinocandins: The Expanding Antifungal Armamentarium

artículo científico

Effect of amphotericin B and micafungin combination on survival, histopathology, and fungal burden in experimental aspergillosis in the p47phox-/- mouse model of chronic granulomatous disease.

artículo científico publicado en 2006

Effects of host response and antifungal therapy on serum and BAL levels of galactomannan and (1→3)-β-D-glucan in experimental invasive pulmonary aspergillosis

artículo científico publicado en 2015

Efficacy and Pharmacokinetics of Fosmanogepix (APX001) in the Treatment of <i>Candida</i> Endophthalmitis and Hematogenous Meningoencephalitis in Non-neutropenic Rabbits

scientific article published on 23 December 2020

Efficacy and safety of generic amphotericin B in experimental pulmonary aspergillosis

artículo científico publicado en 2005

Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans

artículo científico publicado en 2004

Efficacy, plasma pharmacokinetics, and safety of icofungipen, an inhibitor of Candida isoleucyl-tRNA synthetase, in treatment of experimental disseminated candidiasis in persistently neutropenic rabbits

artículo científico publicado en 2005

Efficacy, safety, and plasma pharmacokinetics of escalating dosages of intravenously administered ravuconazole lysine phosphoester for treatment of experimental pulmonary aspergillosis in persistently neutropenic rabbits

artículo científico publicado en 2004

Endpoint Assessment in Rabbit Models of Invasive Pulmonary Aspergillosis and Mucormycosis

artículo científico publicado en 2017

Environmental monitoring for Aspergillus fumigatus in association with an immunosuppressed rabbit model of pulmonary aspergillosis.

scientific article published on September 2013

Experimental pulmonary aspergillosis due to Aspergillus terreus: pathogenesis and treatment of an emerging fungal pathogen resistant to amphotericin B.

artículo científico publicado en 2003

Fungal Infections of the Central Nervous System in Children

artículo científico publicado en 2017

Galactomannan antigenemia after infusion of gluconate-containing Plasma-Lyte

artículo científico publicado en 2011

Galactomannan antigenemia in pediatric oncology patients with invasive aspergillosis

artículo científico publicado en 2008

Galactoxylomannan does not exhibit cross-reactivity in the platelia Aspergillus enzyme immunoassay

artículo científico publicado en 2007

Histoplasmosis-associated cross-reactivity in the BioRad Platelia Aspergillus enzyme immunoassay

artículo científico publicado en 2007

Host biomarkers of invasive pulmonary aspergillosis to monitor therapeutic response

artículo científico publicado en 2014

In vitro combination of isavuconazole with micafungin or amphotericin B deoxycholate against medically important molds

artículo científico publicado en 2014

In vitro combination therapy with isavuconazole against Candida spp.

artículo científico publicado en 2017

Increased virulence of Cunninghamella bertholletiae in experimental pulmonary mucormycosis: correlation with circulating molecular biomarkers, sporangiospore germination and hyphal metabolism

artículo científico publicado en 2012

Intermittent Dosing of Micafungin Is Effective for Treatment of Experimental Disseminated Candidiasis in Persistently Neutropenic Rabbits

artículo científico publicado en 2015

Macrophage colony-stimulating factor enhances phagocytosis and oxidative burst of mononuclear phagocytes againstPenicillium marneffeiconidia

artículo científico publicado el 15 de mayo de 2003

Modeling Invasive Aspergillosis: How Close Are Predicted Antifungal Targets?

scientific article published on 30 September 2020

Molecular Characterization of Uropathogenic Escherichia coli Reveals Emergence of Drug Resistant O15, O22 and O25 Serogroups

artículo científico publicado en 2019

Molecular Detection and Species-Specific Identification of Medically Important Aspergillus Species by Real-Time PCR in Experimental Invasive Pulmonary Aspergillosis

artículo científico publicado el 5 de octubre de 2011

Multidimensional volumetric imaging of pulmonary infiltrates for measuring therapeutic response to antifungal therapy in experimental invasive pulmonary aspergillosis

artículo científico publicado en 2006

Nucleic acid amplification methodologies for the detection of pulmonary mold infections

artículo científico publicado en 2017

Pathogenesis of Aspergillus fumigatus and the kinetics of galactomannan in an in vitro model of early invasive pulmonary aspergillosis: implications for antifungal therapy

artículo científico publicado en 2006

Pharmacodynamics of Posaconazole in Experimental Invasive Pulmonary Aspergillosis: Utility of Serum Galactomannan as a Dynamic Endpoint of Antifungal Efficacy

artículo científico publicado en 2020

Pharmacodynamics of amphotericin B deoxycholate, amphotericin B lipid complex, and liposomal amphotericin B against Aspergillus fumigatus

artículo científico publicado en 2015

Pharmacodynamics of isavuconazole in experimental invasive pulmonary aspergillosis: implications for clinical breakpoints

artículo científico publicado en 2016

Pharmacokinetics and Comprehensive Analysis of the Tissue Distribution of Eravacycline in Rabbits

scholarly article by Vidmantas Petraitis et al published September 2018 in Antimicrobial Agents and Chemotherapy

Pharmacokinetics and Concentration-Dependent Efficacy of Isavuconazole for Treatment of Experimental Invasive Pulmonary Aspergillosis

artículo científico publicado en 2016

Pharmacokinetics and Efficacy of Ceftazidime-Avibactam in the Treatment of Experimental Pneumonia Caused by Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae in Persistently Neutropenic Rabbits

artículo científico publicado en 2020

Pharmacokinetics and Tissue Distribution of Minocycline following Intravenous Administration in Rabbits.

artículo científico publicado en 2017

Pharmacokinetics of Ceftazidime/Avibactam Following Intravenous Administration in Rabbits: Developing the Preclinical Foundation for Treatment of KPC-Kp Pneumonia in Immunocompromised Patients.

artículo científico publicado en 2017

Posaconazole Alone and in Combination with Caspofungin for Treatment of Experimental Exserohilum rostratum Meningoencephalitis: Developing New Strategies for Treatment of Phaeohyphomycosis of the Central Nervous System

artículo científico publicado en 2020

Protein expression profiles distinguish between experimental invasive pulmonary aspergillosis and Pseudomonas pneumonia

artículo científico publicado en 2010

Quantitative multiplexed detection of common pulmonary fungal pathogens by labeled primer polymerase chain reaction

artículo científico publicado en 2014

Role of NADPH oxidase versus neutrophil proteases in antimicrobial host defense

artículo científico publicado en 2011

Successful treatment of Aspergillus ventriculitis through voriconazole adaptive pharmacotherapy, immunomodulation, and therapeutic monitoring of cerebrospinal fluid (1→3)-β-D-glucan

artículo científico publicado en 2016

Synthesis, ADMET Properties, and In Vitro Antimicrobial and Antibiofilm Activity of 5-Nitro-2-thiophenecarbaldehyde N-((E)-(5-Nitrothienyl)methylidene)hydrazone (KTU-286) against Staphylococcus aureus with Defined Resistance Mechanisms

scientific article published on 17 September 2020

The initial 96 hours of invasive pulmonary aspergillosis: histopathology, comparative kinetics of galactomannan and (1->3) β-d-glucan and consequences of delayed antifungal therapy

artículo científico publicado en 2010

The pharmacokinetics and pharmacodynamics of micafungin in experimental hematogenous Candida meningoencephalitis: implications for echinocandin therapy in neonates

artículo científico publicado en 2008

Translational Development and Application of (1→3)-β-d-Glucan for Diagnosis and Therapeutic Monitoring of Invasive Mycoses

artículo científico

Triazole-polyene antagonism in experimental invasive pulmonary aspergillosis: in vitro and in vivo correlation

scientific article published on 28 August 2006

Use of quantitative real-time PCR to study the kinetics of extracellular DNA released from Candida albicans, with implications for diagnosis of invasive Candidiasis

artículo científico publicado en 2006