Lista de obras -

A Flow-Cytometry-Based Approach to Facilitate Quantification, Size Estimation and Characterization of Sub-visible Particles in Protein Solutions

artículo científico publicado en 2015

A caution on the use of murine hemophilia models for comparative immunogenicity studies of FVIII products with different protein compositions

scientific article published on 01 June 2003

Affinity of FVIII-specific antibodies reveals major differences between neutralizing and nonneutralizing antibodies in humans

artículo científico publicado en 2014

Anti-factor VIII IgA as a potential marker of poor prognosis in acquired hemophilia A: results from the GTH-AH 01/2010 study.

artículo científico publicado en 2016

B-cell memory against factor VIII.

artículo científico publicado en 2016

BAX 335 hemophilia B gene therapy clinical trial results - potential impact of CpG sequences on gene expression

artículo científico publicado en 2020

Blockade of the costimulatory CD28-B7 family signal axis enables repeated application of AAV8 gene vectors

artículo científico publicado en 2020

CD4+ T-cell epitopes associated with antibody responses after intravenously and subcutaneously applied human FVIII in humanized hemophilic E17 HLA-DRB1*1501 mice

artículo científico publicado en 2012

Cell surface adhesion molecules and cytokine profiles in primary progressive multiple sclerosis

artículo científico publicado en 2007

Concurrent influenza vaccination reduces anti-FVIII antibody responses in murine hemophilia A.

artículo científico publicado en 2016

Current and future approaches to inhibitor management and aversion

artículo científico publicado en 2006

Detection of Biologically Relevant Low-Titer Neutralizing Antibodies Against Adeno-Associated Virus Require Sensitive In Vitro Assays

artículo científico publicado en 2019

Development of a transgenic mouse model with immune tolerance for human coagulation factor VIIa

artículo científico publicado en 2013

Dexamethasone promotes durable factor VIII -specific tolerance in hemophilia A mice via thymic mechanisms.

artículo científico publicado en 2018

Distinct characteristics of antibody responses against factor VIII in healthy individuals and in different cohorts of hemophilia A patients.

artículo científico publicado en 2012

Evaluation of Factor VIII Polysialylation: Identification of a Longer-Acting Experimental Therapy in Mice and Monkeys

artículo científico publicado en 2019

FVIII-binding IgG modulates FVIII half-life in patients with severe and moderate hemophilia A without inhibitors

artículo científico publicado en 2016

High-dose factor VIII inhibits factor VIII-specific memory B cells in hemophilia A with factor VIII inhibitors

artículo científico publicado en 2005

How Full-Length FVIII Benefits from Its Heterogeneity - Insights into the Role of the B-Domain

scholarly article by Julia Anzengruber et al published 1 April 2019 in Pharmaceutical Research

IVIG induces apoptotic cell death in CD56 NK cells resulting in inhibition of ADCC effector activity of human PBMC

artículo científico publicado en 2018

Immunoglobulins stimulate cultured Schwann cell maturation and promote their potential to induce axonal outgrowth

artículo científico publicado en 2015

Induction of immune tolerance by oral IVIG

artículo científico publicado en 2006

Intravenous Immunoglobulins Are a Therapeutic Option in the Treatment of Multiple Sclerosis Relapse ⬇️

artículo científico publicado el 1 de marzo de 2011

Long-term persistence of anti-factor VIII antibody-secreting cells in hemophilic mice after treatment with human factor VIII

artículo científico publicado en 2002

Maintenance and break of immune tolerance against human factor VIII in a new transgenic hemophilic mouse model

artículo científico publicado en 2011

Mechanisms of action of immune tolerance induction against factor VIII in patients with congenital haemophilia A and factor VIII inhibitors

artículo científico publicado en 2007

Minimal Essential Human Factor VIII Alterations Enhance Secretion and Gene Therapy Efficiency

artículo científico publicado en 2020

Models for assessing immunogenicity and efficacy of new therapeutics for the treatment of haemophilia

artículo científico publicado en 2012

Nonacog gamma, a novel recombinant factor IX with low factor IXa content for treatment and prophylaxis of bleeding episodes

artículo científico publicado en 2015

PEGylated Biopharmaceuticals: Current Experience and Considerations for Nonclinical Development

artículo científico publicado en 2015

Prevalence of Anti-Adeno-Associated Virus Immune Responses in International Cohorts of Healthy Donors

artículo científico publicado en 2019

Preventing restimulation of memory B cells in hemophilia A: a potential new strategy for the treatment of antibody-dependent immune disorders

artículo científico publicado en 2004

Recombinant factor VIII and factor VIII-von Willebrand factor complex do not present danger signals for human dendritic cells

artículo científico publicado en 2006

Risky business of inhibitors: HLA haplotypes, gene polymorphisms, and immune responses

artículo científico publicado en 2014

Single cell analysis of factor VIII-specific T cells in hemophilic mice after treatment with human factor VIII

artículo científico publicado en 2002

Stimulation and inhibition of FVIII-specific memory B-cell responses by CpG-B (ODN 1826), a ligand for Toll-like receptor 9 ⬇️

artículo científico publicado el 6 de enero de 2011

T cell–independent restimulation of FVIII-specific murine memory B cells is facilitated by dendritic cells together with toll-like receptor 7 agonist ⬇️

artículo científico publicado el 25 de julio de 2011

The capacity of the TNF family members 4-1BBL, OX40L, CD70, GITRL, CD30L and LIGHT to costimulate human T cells

artículo científico publicado en 2008

Therapeutic activities of intravenous immunoglobulins in multiple sclerosis involve modulation of chemokine expression

artículo científico publicado en 2009

Tolerance to factor VIII in a transgenic mouse expressing human factor VIII cDNA carrying an Arg(593) to Cys substitution

artículo científico publicado en 2006

Lista de obras de

A Flow-Cytometry-Based Approach to Facilitate Quantification, Size Estimation and Characterization of Sub-visible Particles in Protein Solutions

A caution on the use of murine hemophilia models for comparative immunogenicity studies of FVIII products with different protein compositions

Affinity of FVIII-specific antibodies reveals major differences between neutralizing and nonneutralizing antibodies in humans

Anti-factor VIII IgA as a potential marker of poor prognosis in acquired hemophilia A: results from the GTH-AH 01/2010 study.

B-cell memory against factor VIII.

BAX 335 hemophilia B gene therapy clinical trial results - potential impact of CpG sequences on gene expression

Blockade of the costimulatory CD28-B7 family signal axis enables repeated application of AAV8 gene vectors

CD4+ T-cell epitopes associated with antibody responses after intravenously and subcutaneously applied human FVIII in humanized hemophilic E17 HLA-DRB1*1501 mice

Cell surface adhesion molecules and cytokine profiles in primary progressive multiple sclerosis

Concurrent influenza vaccination reduces anti-FVIII antibody responses in murine hemophilia A.

Current and future approaches to inhibitor management and aversion

Detection of Biologically Relevant Low-Titer Neutralizing Antibodies Against Adeno-Associated Virus Require Sensitive In Vitro Assays

Development of a transgenic mouse model with immune tolerance for human coagulation factor VIIa

Dexamethasone promotes durable factor VIII -specific tolerance in hemophilia A mice via thymic mechanisms.

Distinct characteristics of antibody responses against factor VIII in healthy individuals and in different cohorts of hemophilia A patients.

Evaluation of Factor VIII Polysialylation: Identification of a Longer-Acting Experimental Therapy in Mice and Monkeys

FVIII-binding IgG modulates FVIII half-life in patients with severe and moderate hemophilia A without inhibitors

High-dose factor VIII inhibits factor VIII-specific memory B cells in hemophilia A with factor VIII inhibitors

How Full-Length FVIII Benefits from Its Heterogeneity - Insights into the Role of the B-Domain

IVIG induces apoptotic cell death in CD56 NK cells resulting in inhibition of ADCC effector activity of human PBMC

Immunoglobulins stimulate cultured Schwann cell maturation and promote their potential to induce axonal outgrowth

Induction of immune tolerance by oral IVIG

Intravenous Immunoglobulins Are a Therapeutic Option in the Treatment of Multiple Sclerosis Relapse ⬇️

Long-term persistence of anti-factor VIII antibody-secreting cells in hemophilic mice after treatment with human factor VIII

Maintenance and break of immune tolerance against human factor VIII in a new transgenic hemophilic mouse model

Mechanisms of action of immune tolerance induction against factor VIII in patients with congenital haemophilia A and factor VIII inhibitors

Minimal Essential Human Factor VIII Alterations Enhance Secretion and Gene Therapy Efficiency

Models for assessing immunogenicity and efficacy of new therapeutics for the treatment of haemophilia

Nonacog gamma, a novel recombinant factor IX with low factor IXa content for treatment and prophylaxis of bleeding episodes

PEGylated Biopharmaceuticals: Current Experience and Considerations for Nonclinical Development

Prevalence of Anti-Adeno-Associated Virus Immune Responses in International Cohorts of Healthy Donors

Preventing restimulation of memory B cells in hemophilia A: a potential new strategy for the treatment of antibody-dependent immune disorders

Recombinant factor VIII and factor VIII-von Willebrand factor complex do not present danger signals for human dendritic cells

Risky business of inhibitors: HLA haplotypes, gene polymorphisms, and immune responses

Single cell analysis of factor VIII-specific T cells in hemophilic mice after treatment with human factor VIII

Stimulation and inhibition of FVIII-specific memory B-cell responses by CpG-B (ODN 1826), a ligand for Toll-like receptor 9 ⬇️

T cell–independent restimulation of FVIII-specific murine memory B cells is facilitated by dendritic cells together with toll-like receptor 7 agonist ⬇️

The capacity of the TNF family members 4-1BBL, OX40L, CD70, GITRL, CD30L and LIGHT to costimulate human T cells

Therapeutic activities of intravenous immunoglobulins in multiple sclerosis involve modulation of chemokine expression

Tolerance to factor VIII in a transgenic mouse expressing human factor VIII cDNA carrying an Arg(593) to Cys substitution