Lista de obras -

A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages

artículo científico publicado en 2014

A testing strategy to predict risk for drug-induced liver injury in humans using high-content screen assays and the 'rule-of-two' model

artículo científico publicado en 2014

An integrated bioinformatics infrastructure essential for advancing pharmacogenomics and personalized medicine in the context of the FDA's Critical Path Initiative

artículo científico

An investigation of biomarkers derived from legacy microarray data for their utility in the RNA-seq era

artículo científico publicado en 2014

ArrayTrack--supporting toxicogenomic research at the U.S. Food and Drug Administration National Center for Toxicological Research

artículo científico publicado en 2003

ArrayTrack: An FDA and Public Genomic Tool

artículo científico

ArrayTrack: an FDA and public genomic tool

artículo científico publicado en 2009

Assessing QSAR Limitations - A Regulatory Perspective

Assessing batch effects of genotype calling algorithm BRLMM for the Affymetrix GeneChip Human Mapping 500 K array set using 270 HapMap samples

artículo científico publicado en 2008

Assessing technical performance in differential gene expression experiments with external spike-in RNA control ratio mixtures

artículo científico publicado en 2014

Assessment of prediction confidence and domain extrapolation of two structure-activity relationship models for predicting estrogen receptor binding activity

artículo científico publicado en 2004

Classification of cDNA array genes that have a highly significant discriminative power due to their unique distribution in four brain regions

scientific article published on 01 October 2004

Comparing next-generation sequencing and microarray technologies in a toxicological study of the effects of aristolochic acid on rat kidneys

artículo científico publicado en 2011

Comparison of RNA-seq and microarray-based models for clinical endpoint prediction

artículo científico publicado en 2015

Comprehensive RNA-Seq transcriptomic profiling across 11 organs, 4 ages, and 2 sexes of Fischer 344 rats

artículo científico publicado en 2014

Comprehensively identifying and characterizing the missing gene sequences in human reference genome with integrated analytic approaches

artículo científico publicado en 2013

Correction to: Similarities and differences between variants called with human reference genome HG19 or HG38

scholarly article published in BMC Bioinformatics

Correlation analysis of external RNA controls reveals its utility for assessment of microarray assay

artículo científico publicado en 2008

Critical role of bioinformatics in translating huge amounts of next-generation sequencing data into personalized medicine

artículo científico publicado en 2013

Cross-platform comparability of microarray technology: intra-platform consistency and appropriate data analysis procedures are essential

artículo científico publicado en 2005

Cross-platform ultradeep transcriptomic profiling of human reference RNA samples by RNA-Seq

artículo científico publicado en 2014

DNA microarrays are predictive of cancer prognosis: a re-evaluation

scientific article published on 12 January 2010

Development of public toxicogenomics software for microarray data management and analysis

artículo científico publicado en 2004

Differential gene expression in mouse primary hepatocytes exposed to the peroxisome proliferator-activated receptor alpha agonists

artículo científico publicado en 2006

Dissecting the Characteristics and Dynamics of Human Protein Complexes at Transcriptome Cascade Using RNA-Seq Data

artículo científico publicado en 2013

Emerging technologies for food and drug safety

artículo científico publicado en 2018

Estimating relative noise to signal in DNA microarray data

artículo científico publicado en 2013

Evaluating variations of genotype calling: a potential source of spurious associations in genome-wide association studies

artículo científico publicado en 2010

Evaluation of external RNA controls for the assessment of microarray performance

artículo científico publicado en 2006

Evaluation of gene expression data generated from expired Affymetrix GeneChip® microarrays using MAQC reference RNA samples

artículo científico publicado en 2010

Gaining Confidence on Molecular Classification through Consensus Modeling and Validation

artículo científico publicado en 2006

Incorporating the human gene annotations in different databases significantly improved transcriptomic and genetic analyses

artículo científico publicado en 2013

Integrating time-course microarray gene expression profiles with cytotoxicity for identification of biomarkers in primary rat hepatocytes exposed to cadmium

artículo científico publicado en 2005

Investigation of reproducibility of differentially expressed genes in DNA microarrays through statistical simulation

artículo científico publicado en 2009

Machine Learning Methods for Predicting HLA-Peptide Binding Activity

artículo científico publicado en 2015

Microarray scanner calibration curves: characteristics and implications

artículo científico publicado en 2005

Mold(2), molecular descriptors from 2D structures for chemoinformatics and toxicoinformatics

artículo científico publicado en 2008

Molecular biomarkers: a US FDA effort

artículo científico publicado en 2010

Molecular docking to identify associations between drugs and class I human leukocyte antigens for predicting idiosyncratic drug reactions.

artículo científico publicado en 2015

Multi-class cancer classification by total principal component regression (TPCR) using microarray gene expression data

artículo científico publicado en 2005

Multi-class tumor classification by discriminant partial least squares using microarray gene expression data and assessment of classification models

artículo científico publicado en 2004

Multiclass Decision Forest--a novel pattern recognition method for multiclass classification in microarray data analysis

artículo científico publicado en 2004

Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans

artículo científico publicado en 2017

Next-generation sequencing and its applications in molecular diagnostics

artículo científico publicado en 2011

Performance comparison of one-color and two-color platforms within the MicroArray Quality Control (MAQC) project

artículo científico publicado en 2006

Phytoestrogens and mycoestrogens bind to the rat uterine estrogen receptor

scientific article published on 01 April 2002

Prediction of estrogen receptor binding for 58,000 chemicals using an integrated system of a tree-based model with structural alerts

artículo científico publicado en 2002

QA/QC issues to aid regulatory acceptance of microarray gene expression data

artículo científico publicado en 2007

QA/QC: challenges and pitfalls facing the microarray community and regulatory agencies

artículo científico publicado en 2004

Quality control and quality assessment of data from surface-enhanced laser desorption/ionization (SELDI) time-of flight (TOF) mass spectrometry (MS).

artículo científico publicado en 2005

Rat toxicogenomic study reveals analytical consistency across microarray platforms

artículo científico publicado en 2006

Reproducible and reliable microarray results through quality control: good laboratory proficiency and appropriate data analysis practices are essential

artículo científico publicado en 2007

Selecting a single model or combining multiple models for microarray-based classifier development?--a comparative analysis based on large and diverse datasets generated from the MAQC-II project

artículo científico publicado en 2011

Self-self hybridization as an alternative experiment design to dye swap for two-color microarrays

scientific article published on 01 January 2007

Sequencing XMET genes to promote genotype-guided risk assessment and precision medicine

artículo científico publicado en 2019

Significant variations in alternative splicing patterns and expression profiles between human-mouse orthologs in early embryos

artículo científico publicado en 2016

Similarities and differences between variants called with human reference genome HG19 or HG38

Structure-activity relationship approaches and applications

artículo científico publicado en 2003

Technical reproducibility of genotyping SNP arrays used in genome-wide association studies

artículo científico publicado en 2012

The EDKB: an established knowledge base for endocrine disrupting chemicals

artículo científico publicado en 2010

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

artículo científico publicado en 2006

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

artículo científico publicado en 2010

The accurate prediction of protein family from amino acid sequence by measuring features of sequence fragments

artículo científico publicado en 2009

The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies

artículo científico publicado en 2008

The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance

artículo científico publicado en 2014

The international MAQC Society launches to enhance reproducibility of high-throughput technologies

artículo científico publicado en 2017

Towards the development of an omics data analysis framework

artículo científico publicado en 2020

Transcriptomic profiling of rat liver samples in a comprehensive study design by RNA-Seq

artículo científico publicado en 2014

Understanding and predicting binding between human leukocyte antigens (HLAs) and peptides by network analysis

artículo científico publicado en 2015

Using decision forest to classify prostate cancer samples on the basis of SELDI-TOF MS data: assessing chance correlation and prediction confidence

artículo científico publicado en 2004

Very Important Pool (VIP) genes--an application for microarray-based molecular signatures

artículo científico publicado en 2008

Voluntary exploratory data submissions to the US FDA and the EMA: experience and impact

artículo científico publicado en 2010

Lista de obras de

A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages

A testing strategy to predict risk for drug-induced liver injury in humans using high-content screen assays and the 'rule-of-two' model

An integrated bioinformatics infrastructure essential for advancing pharmacogenomics and personalized medicine in the context of the FDA's Critical Path Initiative

An investigation of biomarkers derived from legacy microarray data for their utility in the RNA-seq era

ArrayTrack--supporting toxicogenomic research at the U.S. Food and Drug Administration National Center for Toxicological Research

ArrayTrack: An FDA and Public Genomic Tool

ArrayTrack: an FDA and public genomic tool

Assessing QSAR Limitations - A Regulatory Perspective

Assessing batch effects of genotype calling algorithm BRLMM for the Affymetrix GeneChip Human Mapping 500 K array set using 270 HapMap samples

Assessing technical performance in differential gene expression experiments with external spike-in RNA control ratio mixtures

Assessment of prediction confidence and domain extrapolation of two structure-activity relationship models for predicting estrogen receptor binding activity

Classification of cDNA array genes that have a highly significant discriminative power due to their unique distribution in four brain regions

Comparing next-generation sequencing and microarray technologies in a toxicological study of the effects of aristolochic acid on rat kidneys

Comparison of RNA-seq and microarray-based models for clinical endpoint prediction

Comprehensive RNA-Seq transcriptomic profiling across 11 organs, 4 ages, and 2 sexes of Fischer 344 rats

Comprehensively identifying and characterizing the missing gene sequences in human reference genome with integrated analytic approaches

Correction to: Similarities and differences between variants called with human reference genome HG19 or HG38

Correlation analysis of external RNA controls reveals its utility for assessment of microarray assay

Critical role of bioinformatics in translating huge amounts of next-generation sequencing data into personalized medicine

Cross-platform comparability of microarray technology: intra-platform consistency and appropriate data analysis procedures are essential

Cross-platform ultradeep transcriptomic profiling of human reference RNA samples by RNA-Seq

DNA microarrays are predictive of cancer prognosis: a re-evaluation

Development of public toxicogenomics software for microarray data management and analysis

Differential gene expression in mouse primary hepatocytes exposed to the peroxisome proliferator-activated receptor alpha agonists

Dissecting the Characteristics and Dynamics of Human Protein Complexes at Transcriptome Cascade Using RNA-Seq Data

Emerging technologies for food and drug safety

Estimating relative noise to signal in DNA microarray data

Evaluating variations of genotype calling: a potential source of spurious associations in genome-wide association studies

Evaluation of external RNA controls for the assessment of microarray performance

Evaluation of gene expression data generated from expired Affymetrix GeneChip® microarrays using MAQC reference RNA samples

Gaining Confidence on Molecular Classification through Consensus Modeling and Validation

Incorporating the human gene annotations in different databases significantly improved transcriptomic and genetic analyses

Integrating time-course microarray gene expression profiles with cytotoxicity for identification of biomarkers in primary rat hepatocytes exposed to cadmium

Investigation of reproducibility of differentially expressed genes in DNA microarrays through statistical simulation

Machine Learning Methods for Predicting HLA-Peptide Binding Activity

Microarray scanner calibration curves: characteristics and implications

Mold(2), molecular descriptors from 2D structures for chemoinformatics and toxicoinformatics

Molecular biomarkers: a US FDA effort

Molecular docking to identify associations between drugs and class I human leukocyte antigens for predicting idiosyncratic drug reactions.

Multi-class cancer classification by total principal component regression (TPCR) using microarray gene expression data

Multi-class tumor classification by discriminant partial least squares using microarray gene expression data and assessment of classification models

Multiclass Decision Forest--a novel pattern recognition method for multiclass classification in microarray data analysis

Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans

Next-generation sequencing and its applications in molecular diagnostics

Performance comparison of one-color and two-color platforms within the MicroArray Quality Control (MAQC) project

Phytoestrogens and mycoestrogens bind to the rat uterine estrogen receptor

Prediction of estrogen receptor binding for 58,000 chemicals using an integrated system of a tree-based model with structural alerts

QA/QC issues to aid regulatory acceptance of microarray gene expression data

QA/QC: challenges and pitfalls facing the microarray community and regulatory agencies

Quality control and quality assessment of data from surface-enhanced laser desorption/ionization (SELDI) time-of flight (TOF) mass spectrometry (MS).

Rat toxicogenomic study reveals analytical consistency across microarray platforms

Reproducible and reliable microarray results through quality control: good laboratory proficiency and appropriate data analysis practices are essential

Selecting a single model or combining multiple models for microarray-based classifier development?--a comparative analysis based on large and diverse datasets generated from the MAQC-II project

Self-self hybridization as an alternative experiment design to dye swap for two-color microarrays

Sequencing XMET genes to promote genotype-guided risk assessment and precision medicine

Significant variations in alternative splicing patterns and expression profiles between human-mouse orthologs in early embryos

Similarities and differences between variants called with human reference genome HG19 or HG38

Structure-activity relationship approaches and applications

Technical reproducibility of genotyping SNP arrays used in genome-wide association studies

The EDKB: an established knowledge base for endocrine disrupting chemicals

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

The accurate prediction of protein family from amino acid sequence by measuring features of sequence fragments

The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies

The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance

The international MAQC Society launches to enhance reproducibility of high-throughput technologies

Towards the development of an omics data analysis framework

Transcriptomic profiling of rat liver samples in a comprehensive study design by RNA-Seq

Understanding and predicting binding between human leukocyte antigens (HLAs) and peptides by network analysis

Using decision forest to classify prostate cancer samples on the basis of SELDI-TOF MS data: assessing chance correlation and prediction confidence

Very Important Pool (VIP) genes--an application for microarray-based molecular signatures

Voluntary exploratory data submissions to the US FDA and the EMA: experience and impact