Lista de obras - Eduardo N Chini - Dominio Público Uruguay

A High Dose of Isoniazid Disturbs Endobiotic Homeostasis in Mouse Liver

artículo científico publicado en 2016

A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD Decline

scholarly article by Mariana G Tarragó published in May 2018

A methionine-Mettl3-N6-methyladenosine axis promotes polycystic kidney disease

artículo científico publicado en 2021

A novel form of Deleted in breast cancer 1 (DBC1) lacking the N-terminal domain does not bind SIRT1 and is dynamically regulated in vivo

artículo científico publicado en 2019

Abscisic acid controls calcium-dependent egress and development in Toxoplasma gondii

artículo científico publicado en 2008

Agonist-induced cyclic ADP ribose production in airway smooth muscle.

artículo científico publicado en 2006

Altered behavioral and metabolic circadian rhythms in mice with disrupted NAD+ oscillation

artículo científico publicado en 2011

CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism.

artículo científico publicado en 2016

CD38 as a regulator of cellular NAD: a novel potential pharmacological target for metabolic conditions

artículo científico publicado en 2009

CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels

artículo científico publicado en 2020

CD38 expression, function, and gene resequencing in a human lymphoblastoid cell line-based model system

artículo científico publicado en 2010

CD38 is the major enzyme responsible for synthesis of nicotinic acid-adenine dinucleotide phosphate in mammalian tissues

artículo científico publicado en 2002

Calcium regulation and signaling in apicomplexan parasites.

artículo científico publicado en 2008

Cardiomyopathy and Worsened Ischemic Heart Failure in SM22-α Cre-Mediated Neuropilin-1 Null Mice: Dysregulation of PGC1α and Mitochondrial Homeostasis.

artículo científico publicado en 2015

Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity.

artículo científico publicado en 2015

Complications after unintentional intra-arterial injection of drugs: risks, outcomes, and management strategies

artículo científico publicado en 2005

Correction: SIRT1 Activity Is Linked to Its Brain Region-Specific Phosphorylation and Is Impaired in Huntington's Disease Mice

artículo científico publicado en 2016

Critical Role of Astrocyte NAD+ Glycohydrolase in Myelin Injury and Regeneration

artículo científico publicado en 2021

DBC1 (Deleted in Breast Cancer 1) modulates the stability and function of the nuclear receptor Rev-erbα ⬇️

artículo científico publicado el 1 de mayo de 2013

DBC1 is a suppressor of B cell activation by negatively regulating alternative NF-κB transcriptional activity.

artículo científico publicado en 2014

Deleted in Breast Cancer 1 Suppresses B Cell Activation through RelB and Is Regulated by IKKα Phosphorylation.

artículo científico publicado en 2015

Deleted in Breast Cancer 1 regulates cellular senescence during obesity

artículo científico publicado en 2014

Deleted in breast cancer 1 (DBC1) protein regulates hepatic gluconeogenesis

scientific article published on 10 January 2014

Deleted in breast cancer 1 limits adipose tissue fat accumulation and plays a key role in the development of metabolic syndrome phenotype

artículo científico publicado en 2014

Deleted in breast cancer-1 (DBC-1) in the interface between metabolism, aging and cancer ⬇️

artículo científico publicado el 23 de agosto de 2013

Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice

artículo científico publicado en 2010

Dietary restriction: standing up for sirtuins

artículo científico publicado en 2010

Differential effects of volatile anesthetics on M3 muscarinic receptor coupling to the Galphaq heterotrimeric G protein

artículo científico publicado en 2006

Effect of halothane on cADP-ribose-induced Ca(2+) release system in tracheal smooth muscle.

artículo científico publicado en 2002

Endurance capacity, not body size, determines physical activity levels: role of skeletal muscle PEPCK.

artículo científico publicado en 2009

Erratum to: Loss of HSulf-1 promotes altered lipid metabolism in ovarian cancer

artículo científico publicado en 2014

Evidence that the cADPR signalling pathway controls calcium-mediated microneme secretion in Toxoplasma gondii

artículo científico publicado en 2005

Flavonoid apigenin is an inhibitor of the NAD+ ase CD38: implications for cellular NAD+ metabolism, protein acetylation, and treatment of metabolic syndrome

artículo científico publicado en 2012

Food Restriction Ameliorates the Development of Polycystic Kidney Disease

artículo científico publicado en 2015

Genetic deletion of CD38 confers post-ischemic myocardial protection through preserved pyridine nucleotides.

artículo científico publicado en 2018

Growth hormone signaling in muscle and adipose tissue of obese human subjects: associations with measures of body composition and interaction with resveratrol treatment

artículo científico publicado en 2014

HDAC3 Is Negatively Regulated by the Nuclear Protein DBC1 ⬇️

artículo científico publicado el 28 de octubre de 2010

HSulf-1 deficiency dictates a metabolic reprograming of glycolysis and TCA cycle in ovarian cancer

artículo científico publicado en 2015

Hypertensive crisis in a patient undergoing percutaneous radiofrequency ablation of an adrenal mass under general anesthesia

artículo científico publicado en 2004

Implications of the PAPP-A-IGFBP-IGF-1 pathway in the pathogenesis and treatment of polycystic kidney disease

scientific article published on 19 June 2020

Integrin ligands mobilize Ca2+ from ryanodine receptor-gated stores and lysosome-related acidic organelles in pulmonary arterial smooth muscle cells

artículo científico publicado en 2006

Interactions between intracellular Ca2+ stores: Ca2+ released from the NAADP pool potentiates cADPR-induced Ca2+ release

artículo científico publicado en 2002

Krüppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes of the young

artículo científico publicado en 2013

Loss of HSulf-1 promotes altered lipid metabolism in ovarian cancer

artículo científico publicado en 2014

Measuring CD38 Hydrolase and Cyclase Activities: 1,N6-Ethenonicotinamide Adenine Dinucleotide (ε-NAD) and Nicotinamide Guanine Dinucleotide (NGD) Fluorescence-based Methods

artículo científico publicado en 2018

Metabolism of cyclic ADP-ribose: Zinc is an endogenous modulator of the cyclase/NAD glycohydrolase ratio of a CD38-like enzyme from human seminal fluid

artículo científico publicado en 2004

Metalloproteinase PAPP-A regulation of IGF-1 contributes to polycystic kidney disease pathogenesis

artículo científico publicado en 2020

NAADP as a second messenger: neither CD38 nor base-exchange reaction are necessary for in vivo generation of NAADP in myometrial cells

artículo científico publicado en 2006

NAD and the aging process: Role in life, death and everything in between

artículo científico publicado en 2016

Nicotinic acid adenine dinucleotide phosphate: a new intracellular second messenger?

artículo científico publicado en 2002

Of Mice and Men: NAD+ Boosting with Niacin Provides Hope for Mitochondrial Myopathy Patients

artículo científico publicado en 2020

Phenotypic Characterization of Mice Carrying Homozygous Deletion of KLF11, a Gene in Which Mutations Cause Human Neonatal and MODY VII Diabetes

artículo científico publicado en 2015

Plants, endosymbionts and parasites: Abscisic acid and calcium signaling

artículo científico publicado en 2008

Postoperative outcome of patients with narcolepsy. A retrospective analysis

artículo científico publicado en 2005

Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer

artículo científico publicado en 2017

Reduction in soluble guanylyl cyclase-specific activity following prolonged treatment of porcine pulmonary artery with nitric oxide

artículo científico publicado en 2007

Regulation of SIRT 1 mediated NAD dependent deacetylation: a novel role for the multifunctional enzyme CD38

artículo científico publicado en 2006

Regulation of intracellular levels of NAD: a novel role for CD38.

artículo científico publicado en 2006

Resveratrol delays Wallerian degeneration in a NAD+ and DBC1 dependent manner ⬇️

artículo científico publicado el 16 de noviembre de 2013

Rho GTPase effectors and NAD metabolism in cancer immune suppression.

artículo científico publicado en 2017

Role of CD38 in myometrial Ca2+ transients: modulation by progesterone

artículo científico publicado en 2004

Role of deleted in breast cancer 1 (DBC1) protein in SIRT1 deacetylase activation induced by protein kinase A and AMP-activated protein kinase.

artículo científico publicado en 2012

Role of the second-messenger cyclic-adenosine 5'-diphosphate-ribose on adrenocorticotropin secretion from pituitary cells.

artículo científico publicado en 2005

Role of transient receptor potential C3 in TNF-alpha-enhanced calcium influx in human airway myocytes

artículo científico publicado en 2006

SIRT1 Activity Is Linked to Its Brain Region-Specific Phosphorylation and Is Impaired in Huntington's Disease Mice

artículo científico publicado en 2016

SIRT1-Activating Compounds (STAC) Negatively Regulate Pancreatic Cancer Cell Growth and Viability Through a SIRT1 Lysosomal-Dependent Pathway

artículo científico publicado en 2015

Spontaneous activity, economy of activity, and resistance to diet-induced obesity in rats bred for high intrinsic aerobic capacity

artículo científico publicado en 2010

Targeting CD38 Enhances the Antileukemic Activity of Ibrutinib in Chronic Lymphocytic Leukemia

scientific article published on 02 April 2019

Targeting CD38 is lethal to Breg-like chronic lymphocytic leukemia cells and Tregs, but restores CD8+ T-cell responses

scientific article published on 01 May 2020

Targeting CD38-dependent NAD+ metabolism to mitigate multiple organ fibrosis

artículo científico publicado en 2020

Targeting of NAD metabolism in pancreatic cancer cells: potential novel therapy for pancreatic tumors.

scientific article published on 11 September 2013

Targeting senescent cells alleviates obesity-induced metabolic dysfunction

artículo científico publicado en 2019

The Multi-faceted Ecto-enzyme CD38: Roles in Immunomodulation, Cancer, Aging, and Metabolic Diseases

artículo científico publicado en 2019

The NADase CD38 is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD decline

artículo científico publicado en 2019

The NADase enzyme CD38: an emerging pharmacological target for systemic sclerosis, systemic lupus erythematosus and rheumatoid arthritis

scientific article published on 15 September 2020

The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism.

artículo científico publicado en 2017

The Pharmacology of CD38/NADase: An Emerging Target in Cancer and Diseases of Aging

artículo científico publicado en 2018

The cyclic-ADP-ribose signaling pathway in human myometrium

artículo científico publicado en 2002

The enzyme CD38 (a NAD glycohydrolase, EC 3.2.2.5) is necessary for the development of diet-induced obesity

artículo científico publicado en 2007

The role of cyclic-ADP-ribose-signaling pathway in oxytocin-induced Ca2+ transients in human myometrium cells.

artículo científico publicado en 2003

Tissue-resident CD8+ T cells drive age-associated chronic lung sequelae after viral pneumonia

artículo científico publicado en 2020

Tissue-resident CD8+ T cells drive age-associated chronic lung sequelae following viral pneumonia

artículo científico publicado en 2020

To be or not to be ... nicotinic acid adenine dinucleotide phosphate (NAADP): a new intracellular second messenger?

artículo científico publicado en 2004

Two Different Methods of Quantification of Oxidized Nicotinamide Adenine Dinucleotide (NAD+) and Reduced Nicotinamide Adenine Dinucleotide (NADH) Intracellular Levels: Enzymatic Coupled Cycling Assay and Ultra-performance Liquid Chromatography (UPLC

artículo científico publicado en 2018

Wnt-induced, TRP53-mediated Cell Cycle Arrest of Precursors Underlies Interstitial Cell of Cajal Depletion during Aging

scientific article published on 06 August 2020

Lista de obras de Eduardo N Chini

A High Dose of Isoniazid Disturbs Endobiotic Homeostasis in Mouse Liver

A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD Decline

A methionine-Mettl3-N<sup>6</sup>-methyladenosine axis promotes polycystic kidney disease

A novel form of Deleted in breast cancer 1 (DBC1) lacking the N-terminal domain does not bind SIRT1 and is dynamically regulated in vivo

Abscisic acid controls calcium-dependent egress and development in Toxoplasma gondii

Agonist-induced cyclic ADP ribose production in airway smooth muscle.

Altered behavioral and metabolic circadian rhythms in mice with disrupted NAD+ oscillation

CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism.

CD38 as a regulator of cellular NAD: a novel potential pharmacological target for metabolic conditions

CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels

CD38 expression, function, and gene resequencing in a human lymphoblastoid cell line-based model system

CD38 is the major enzyme responsible for synthesis of nicotinic acid-adenine dinucleotide phosphate in mammalian tissues

Calcium regulation and signaling in apicomplexan parasites.

Cardiomyopathy and Worsened Ischemic Heart Failure in SM22-α Cre-Mediated Neuropilin-1 Null Mice: Dysregulation of PGC1α and Mitochondrial Homeostasis.

Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity.

Complications after unintentional intra-arterial injection of drugs: risks, outcomes, and management strategies

Correction: SIRT1 Activity Is Linked to Its Brain Region-Specific Phosphorylation and Is Impaired in Huntington's Disease Mice

Critical Role of Astrocyte NAD<sup>+</sup> Glycohydrolase in Myelin Injury and Regeneration

DBC1 (Deleted in Breast Cancer 1) modulates the stability and function of the nuclear receptor Rev-erbα ⬇️

DBC1 is a suppressor of B cell activation by negatively regulating alternative NF-κB transcriptional activity.

Deleted in Breast Cancer 1 Suppresses B Cell Activation through RelB and Is Regulated by IKKα Phosphorylation.

Deleted in Breast Cancer 1 regulates cellular senescence during obesity

Deleted in breast cancer 1 (DBC1) protein regulates hepatic gluconeogenesis

Deleted in breast cancer 1 limits adipose tissue fat accumulation and plays a key role in the development of metabolic syndrome phenotype

Deleted in breast cancer-1 (DBC-1) in the interface between metabolism, aging and cancer ⬇️

Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice

Dietary restriction: standing up for sirtuins

Differential effects of volatile anesthetics on M3 muscarinic receptor coupling to the Galphaq heterotrimeric G protein

Effect of halothane on cADP-ribose-induced Ca(2+) release system in tracheal smooth muscle.

Endurance capacity, not body size, determines physical activity levels: role of skeletal muscle PEPCK.

Erratum to: Loss of HSulf-1 promotes altered lipid metabolism in ovarian cancer

Evidence that the cADPR signalling pathway controls calcium-mediated microneme secretion in Toxoplasma gondii

Flavonoid apigenin is an inhibitor of the NAD+ ase CD38: implications for cellular NAD+ metabolism, protein acetylation, and treatment of metabolic syndrome

Food Restriction Ameliorates the Development of Polycystic Kidney Disease

Genetic deletion of CD38 confers post-ischemic myocardial protection through preserved pyridine nucleotides.

Growth hormone signaling in muscle and adipose tissue of obese human subjects: associations with measures of body composition and interaction with resveratrol treatment

HDAC3 Is Negatively Regulated by the Nuclear Protein DBC1 ⬇️

HSulf-1 deficiency dictates a metabolic reprograming of glycolysis and TCA cycle in ovarian cancer

Hypertensive crisis in a patient undergoing percutaneous radiofrequency ablation of an adrenal mass under general anesthesia

Implications of the PAPP-A-IGFBP-IGF-1 pathway in the pathogenesis and treatment of polycystic kidney disease

Integrin ligands mobilize Ca2+ from ryanodine receptor-gated stores and lysosome-related acidic organelles in pulmonary arterial smooth muscle cells

Interactions between intracellular Ca2+ stores: Ca2+ released from the NAADP pool potentiates cADPR-induced Ca2+ release

Krüppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes of the young

Loss of HSulf-1 promotes altered lipid metabolism in ovarian cancer

Measuring CD38 Hydrolase and Cyclase Activities: 1,N6-Ethenonicotinamide Adenine Dinucleotide (ε-NAD) and Nicotinamide Guanine Dinucleotide (NGD) Fluorescence-based Methods

Metabolism of cyclic ADP-ribose: Zinc is an endogenous modulator of the cyclase/NAD glycohydrolase ratio of a CD38-like enzyme from human seminal fluid

Metalloproteinase PAPP-A regulation of IGF-1 contributes to polycystic kidney disease pathogenesis

NAADP as a second messenger: neither CD38 nor base-exchange reaction are necessary for in vivo generation of NAADP in myometrial cells

NAD and the aging process: Role in life, death and everything in between

Nicotinic acid adenine dinucleotide phosphate: a new intracellular second messenger?

Of Mice and Men: NAD+ Boosting with Niacin Provides Hope for Mitochondrial Myopathy Patients

Phenotypic Characterization of Mice Carrying Homozygous Deletion of KLF11, a Gene in Which Mutations Cause Human Neonatal and MODY VII Diabetes

Plants, endosymbionts and parasites: Abscisic acid and calcium signaling

Postoperative outcome of patients with narcolepsy. A retrospective analysis

Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer

Reduction in soluble guanylyl cyclase-specific activity following prolonged treatment of porcine pulmonary artery with nitric oxide

Regulation of SIRT 1 mediated NAD dependent deacetylation: a novel role for the multifunctional enzyme CD38

Regulation of intracellular levels of NAD: a novel role for CD38.

Resveratrol delays Wallerian degeneration in a NAD+ and DBC1 dependent manner ⬇️

Rho GTPase effectors and NAD metabolism in cancer immune suppression.

Role of CD38 in myometrial Ca2+ transients: modulation by progesterone

Role of deleted in breast cancer 1 (DBC1) protein in SIRT1 deacetylase activation induced by protein kinase A and AMP-activated protein kinase.

Role of the second-messenger cyclic-adenosine 5'-diphosphate-ribose on adrenocorticotropin secretion from pituitary cells.

Role of transient receptor potential C3 in TNF-alpha-enhanced calcium influx in human airway myocytes

SIRT1 Activity Is Linked to Its Brain Region-Specific Phosphorylation and Is Impaired in Huntington's Disease Mice

SIRT1-Activating Compounds (STAC) Negatively Regulate Pancreatic Cancer Cell Growth and Viability Through a SIRT1 Lysosomal-Dependent Pathway

Spontaneous activity, economy of activity, and resistance to diet-induced obesity in rats bred for high intrinsic aerobic capacity

Targeting CD38 Enhances the Antileukemic Activity of Ibrutinib in Chronic Lymphocytic Leukemia

Targeting CD38 is lethal to Breg-like chronic lymphocytic leukemia cells and Tregs, but restores CD8+ T-cell responses

Targeting CD38-dependent NAD<sup>+</sup> metabolism to mitigate multiple organ fibrosis

Targeting of NAD metabolism in pancreatic cancer cells: potential novel therapy for pancreatic tumors.

Targeting senescent cells alleviates obesity-induced metabolic dysfunction

The Multi-faceted Ecto-enzyme CD38: Roles in Immunomodulation, Cancer, Aging, and Metabolic Diseases

The NADase CD38 is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD decline

The NADase enzyme CD38: an emerging pharmacological target for systemic sclerosis, systemic lupus erythematosus and rheumatoid arthritis

The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism.

The Pharmacology of CD38/NADase: An Emerging Target in Cancer and Diseases of Aging

The cyclic-ADP-ribose signaling pathway in human myometrium

The enzyme CD38 (a NAD glycohydrolase, EC 3.2.2.5) is necessary for the development of diet-induced obesity