Lista de obras -

3',4'-Bis-difluoromethoxycinnamoylanthranilate (FT061): an orally-active antifibrotic agent that reduces albuminuria in a rat model of progressive diabetic nephropathy.

artículo científico publicado en 2013

3′,4′-Dihydroxyflavonol Antioxidant Attenuates Diastolic Dysfunction and Cardiac Remodeling in Streptozotocin-Induced Diabetic m(Ren2)27 Rats ⬇️

artículo científico publicado el 28 de julio de 2011

A new anti-fibrotic drug attenuates cardiac remodeling and systolic dysfunction following experimental myocardial infarction

artículo científico publicado en 2012

A purpose-synthesised anti-fibrotic agent attenuates experimental kidney diseases in the rat

artículo científico publicado en 2012

Aliskiren increases bradykinin and tissue kallikrein mRNA levels in the heart

artículo científico publicado en 2011

Atrial Remodeling in an Ovine Model of Anthracycline-Induced Nonischemic Cardiomyopathy: Remodeling of the Same Sort

artículo científico publicado en 2011

Atrial arrhythmia in ageing spontaneously hypertensive rats: unraveling the substrate in hypertension and ageing

artículo científico publicado en 2013

Cardiac Repair With a Novel Population of Mesenchymal Stem Cells Resident in the Human Heart

artículo científico publicado en 2015

Cells expressing the stem cell factor receptor, c-kit, contribute to neoangiogenesis in diabetes

artículo científico publicado en 2005

Characterization of cardiac remodeling in a large animal "one-kidney, one-clip" hypertensive model

artículo científico publicado en 2010

Chloride channel ClC-5 binds to aspartyl aminopeptidase to regulate renal albumin endocytosis

scientific article published on 13 January 2015

Culture-modified bone marrow cells attenuate cardiac and renal injury in a chronic kidney disease rat model via a novel antifibrotic mechanism

artículo científico publicado en 2010

Effects on protein kinase C-beta inhibition on glomerular vascular endothelial growth factor expression and endothelial cells in advanced experimental diabetic nephropathy

scientific article published on 23 May 2007

Evaluation and optimization of antifibrotic activity of cinnamoyl anthranilates

artículo científico publicado en 2009

Expression, localization, and function of the thioredoxin system in diabetic nephropathy

artículo científico publicado en 2009

FT011, a Novel Cardiorenal Protective Drug, Reduces Inflammation, Gliosis and Vascular Injury in Rats with Diabetic Retinopathy

artículo científico publicado en 2015

FT23, an orally active antifibrotic compound, attenuates structural and functional abnormalities in an experimental model of diabetic cardiomyopathy

artículo científico publicado en 2012

Fas-induced apoptosis is a feature of progressive diabetic nephropathy in transgenic (mRen-2)27 rats: attenuation with renin-angiotensin blockade

artículo científico publicado en 2004

High glucose induces Smad activation via the transcriptional coregulator p300 and contributes to cardiac fibrosis and hypertrophy

artículo científico publicado en 2014

High glucose induces macrophage inflammatory protein-3 alpha in renal proximal tubule cells via a transforming growth factor-beta 1 dependent mechanism

artículo científico publicado en 2007

High glucose-induced thioredoxin-interacting protein in renal proximal tubule cells is independent of transforming growth factor-beta1.

artículo científico publicado en 2007

Hypertension and atrial fibrillation: evidence of progressive atrial remodeling with electrostructural correlate in a conscious chronically instrumented ovine model

artículo científico publicado en 2010

Impaired cardiac anti-oxidant activity in diabetes: human and correlative experimental studies

artículo científico publicado en 2014

In vivo visualization of albumin degradation in the proximal tubule

artículo científico publicado en 2008

Inhibition of protein kinase C reduces left ventricular fibrosis and dysfunction following myocardial infarction

artículo científico publicado en 2005

Inhibition of the epidermal growth factor receptor preserves podocytes and attenuates albuminuria in experimental diabetic nephropathy ⬇️

artículo científico publicado el 1 de agosto de 2011

Intervention with tranilast attenuates renal pathology and albuminuria in advanced experimental diabetic nephropathy

scientific article published on 01 January 2003

Macrophage infiltration and cellular proliferation in the non-ischemic kidney and heart following prolonged unilateral renal ischemia

scientific article published on 15 June 2007

Mast cell infiltration and chemokine expression in progressive renal disease

artículo científico publicado en 2003

Myocardial infarction impairs renal function, induces renal interstitial fibrosis, and increases renal KIM-1 expression: implications for cardiorenal syndrome

artículo científico publicado en 2012

Nitrosative Stress as a Modulator of Inflammatory Change in a Model of Takotsubo Syndrome

artículo científico publicado en 2018

Obesity results in progressive atrial structural and electrical remodeling: Implications for atrial fibrillation

artículo científico publicado en 2012

Protein kinase C beta inhibition attenuates the progression of experimental diabetic nephropathy in the presence of continued hypertension

artículo científico publicado en 2003

Protein kinase C-beta inhibition attenuates the progression of nephropathy in non-diabetic kidney disease

artículo científico publicado en 2009

Protein kinase Cbeta inhibition attenuates osteopontin expression, macrophage recruitment, and tubulointerstitial injury in advanced experimental diabetic nephropathy

artículo científico publicado en 2005

Relaxin ameliorates fibrosis in experimental diabetic cardiomyopathy

artículo científico publicado en 2008

Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of hypertension and diabetic nephropathy

artículo científico publicado en 2006

Role of Kruppel-like factor 6 in transforming growth factor-beta1-induced epithelial-mesenchymal transition of proximal tubule cells

artículo científico publicado en 2008

Role of the eNOS-NO system in regulating the antiproteinuric effects of VEGF receptor 2 inhibition in diabetes

artículo científico publicado en 2013

Short-term hypertension is associated with the development of atrial fibrillation substrate: a study in an ovine hypertensive model.

artículo científico publicado en 2009

Soluble epoxide hydrolase inhibition exerts beneficial anti-remodeling actions post-myocardial infarction

artículo científico publicado en 2012

Targeted inhibition of activin receptor-like kinase 5 signaling attenuates cardiac dysfunction following myocardial infarction

artículo científico publicado en 2010

The anti-fibrotic hormone relaxin is not reno-protective, despite being active, in an experimental model of type 1 diabetes

scientific article published on 01 September 2013

The differential regulation of Smad7 in kidney tubule cells by connective tissue growth factor and transforming growth factor-beta1.

artículo científico

Thioredoxin-interacting protein: a potential therapeutic target for treatment of progressive fibrosis in diabetic nephropathy.

artículo científico publicado en 2015

Tranilast ameliorates experimental mesangial proliferative glomerulonephritis

artículo científico publicado en 2008

Tranilast attenuates cardiac matrix deposition in experimental diabetes: role of transforming growth factor-beta

artículo científico publicado en 2005

Tranilast attenuates diastolic dysfunction and structural injury in experimental diabetic cardiomyopathy

scientific article published on 24 August 2007

Tranilast attenuates structural and functional aspects of renal injury in the remnant kidney model

artículo científico publicado en 2004

Tranilast attenuates the up-regulation of thioredoxin-interacting protein and oxidative stress in an experimental model of diabetic nephropathy.

artículo científico publicado en 2010

Transforming growth factor-beta in human diabetic nephropathy: effects of ACE inhibition.

artículo científico publicado en 2006

Widespread Coronary Dysfunction in the Absence of HDL Receptor SR-B1 in an Ischemic Cardiomyopathy Mouse Model

artículo científico publicado en 2017

Lista de obras de

3',4'-Bis-difluoromethoxycinnamoylanthranilate (FT061): an orally-active antifibrotic agent that reduces albuminuria in a rat model of progressive diabetic nephropathy.

3′,4′-Dihydroxyflavonol Antioxidant Attenuates Diastolic Dysfunction and Cardiac Remodeling in Streptozotocin-Induced Diabetic m(Ren2)27 Rats ⬇️

A new anti-fibrotic drug attenuates cardiac remodeling and systolic dysfunction following experimental myocardial infarction

A purpose-synthesised anti-fibrotic agent attenuates experimental kidney diseases in the rat

Aliskiren increases bradykinin and tissue kallikrein mRNA levels in the heart

Atrial Remodeling in an Ovine Model of Anthracycline-Induced Nonischemic Cardiomyopathy: Remodeling of the Same Sort

Atrial arrhythmia in ageing spontaneously hypertensive rats: unraveling the substrate in hypertension and ageing

Cardiac Repair With a Novel Population of Mesenchymal Stem Cells Resident in the Human Heart

Cells expressing the stem cell factor receptor, c-kit, contribute to neoangiogenesis in diabetes

Characterization of cardiac remodeling in a large animal "one-kidney, one-clip" hypertensive model

Chloride channel ClC-5 binds to aspartyl aminopeptidase to regulate renal albumin endocytosis

Culture-modified bone marrow cells attenuate cardiac and renal injury in a chronic kidney disease rat model via a novel antifibrotic mechanism

Effects on protein kinase C-beta inhibition on glomerular vascular endothelial growth factor expression and endothelial cells in advanced experimental diabetic nephropathy

Evaluation and optimization of antifibrotic activity of cinnamoyl anthranilates

Expression, localization, and function of the thioredoxin system in diabetic nephropathy

FT011, a Novel Cardiorenal Protective Drug, Reduces Inflammation, Gliosis and Vascular Injury in Rats with Diabetic Retinopathy

FT23, an orally active antifibrotic compound, attenuates structural and functional abnormalities in an experimental model of diabetic cardiomyopathy

Fas-induced apoptosis is a feature of progressive diabetic nephropathy in transgenic (mRen-2)27 rats: attenuation with renin-angiotensin blockade

High glucose induces Smad activation via the transcriptional coregulator p300 and contributes to cardiac fibrosis and hypertrophy

High glucose induces macrophage inflammatory protein-3 alpha in renal proximal tubule cells via a transforming growth factor-beta 1 dependent mechanism

High glucose-induced thioredoxin-interacting protein in renal proximal tubule cells is independent of transforming growth factor-beta1.

Hypertension and atrial fibrillation: evidence of progressive atrial remodeling with electrostructural correlate in a conscious chronically instrumented ovine model

Impaired cardiac anti-oxidant activity in diabetes: human and correlative experimental studies

In vivo visualization of albumin degradation in the proximal tubule

Inhibition of protein kinase C reduces left ventricular fibrosis and dysfunction following myocardial infarction

Inhibition of the epidermal growth factor receptor preserves podocytes and attenuates albuminuria in experimental diabetic nephropathy ⬇️

Intervention with tranilast attenuates renal pathology and albuminuria in advanced experimental diabetic nephropathy

Macrophage infiltration and cellular proliferation in the non-ischemic kidney and heart following prolonged unilateral renal ischemia

Mast cell infiltration and chemokine expression in progressive renal disease

Myocardial infarction impairs renal function, induces renal interstitial fibrosis, and increases renal KIM-1 expression: implications for cardiorenal syndrome

Nitrosative Stress as a Modulator of Inflammatory Change in a Model of Takotsubo Syndrome

Obesity results in progressive atrial structural and electrical remodeling: Implications for atrial fibrillation

Protein kinase C beta inhibition attenuates the progression of experimental diabetic nephropathy in the presence of continued hypertension

Protein kinase C-beta inhibition attenuates the progression of nephropathy in non-diabetic kidney disease

Protein kinase Cbeta inhibition attenuates osteopontin expression, macrophage recruitment, and tubulointerstitial injury in advanced experimental diabetic nephropathy

Relaxin ameliorates fibrosis in experimental diabetic cardiomyopathy

Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of hypertension and diabetic nephropathy

Role of Kruppel-like factor 6 in transforming growth factor-beta1-induced epithelial-mesenchymal transition of proximal tubule cells

Role of the eNOS-NO system in regulating the antiproteinuric effects of VEGF receptor 2 inhibition in diabetes

Short-term hypertension is associated with the development of atrial fibrillation substrate: a study in an ovine hypertensive model.

Soluble epoxide hydrolase inhibition exerts beneficial anti-remodeling actions post-myocardial infarction

Targeted inhibition of activin receptor-like kinase 5 signaling attenuates cardiac dysfunction following myocardial infarction

The anti-fibrotic hormone relaxin is not reno-protective, despite being active, in an experimental model of type 1 diabetes

The differential regulation of Smad7 in kidney tubule cells by connective tissue growth factor and transforming growth factor-beta1.

Thioredoxin-interacting protein: a potential therapeutic target for treatment of progressive fibrosis in diabetic nephropathy.

Tranilast ameliorates experimental mesangial proliferative glomerulonephritis

Tranilast attenuates cardiac matrix deposition in experimental diabetes: role of transforming growth factor-beta

Tranilast attenuates diastolic dysfunction and structural injury in experimental diabetic cardiomyopathy

Tranilast attenuates structural and functional aspects of renal injury in the remnant kidney model

Tranilast attenuates the up-regulation of thioredoxin-interacting protein and oxidative stress in an experimental model of diabetic nephropathy.

Transforming growth factor-beta in human diabetic nephropathy: effects of ACE inhibition.

Widespread Coronary Dysfunction in the Absence of HDL Receptor SR-B1 in an Ischemic Cardiomyopathy Mouse Model