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"Back to a false normality": new intriguing mechanisms of resistance to PARP inhibitors

artículo científico publicado en 2016

A headlight on liquid biopsies: a challenging tool for breast cancer management.

artículo científico publicado en 2016

A new germline mutation in BRCA1 gene in a sicilian family with ovarian cancer

article

Absence of germline CDKN2A mutation in Sicilian patients with familial malignant melanoma: Could it be a population-specific genetic signature?

artículo científico publicado en 2015

An update on the conquests and perspectives of cardio-oncology in the field of tumor angiogenesis-targeting TKI-based therapy

scientific article published on 07 May 2019

Analysis of germline gene copy number variants of patients with sporadic pancreatic adenocarcinoma reveals specific variations

scientific article published on 09 November 2013

Analysis of miRNA expression profile induced by short term starvation in breast cancer cells treated with doxorubicin

artículo científico publicado en 2017

Analysis of molecular mechanisms and anti-tumoural effects of zoledronic acid in breast cancer cells.

artículo científico publicado en 2012

Analysis of tissue and circulating microRNA expression during metaplastic transformation of the esophagus

artículo científico publicado en 2016

Anti-endothelin drugs in solid tumors

artículo científico publicado en 2010

BRCA1 genetic testing in 106 breast and ovarian cancer families from southern Italy (Sicily): a mutation analyses

article

Baseline plasma levels of soluble PD-1, PD-L1, and BTN3A1 predict response to nivolumab treatment in patients with metastatic renal cell carcinoma: a step toward a biomarker for therapeutic decisions

scientific article published on 27 October 2020

Beyond evidence-based data: scientific rationale and tumor behavior to drive sequential and personalized therapeutic strategies for the treatment of metastatic renal cell carcinoma

artículo científico publicado en 2016

Can KRAS and BRAF mutations limit the benefit of liver resection in metastatic colorectal cancer patients? A systematic review and meta-analysis.

artículo científico publicado en 2016

Can the microRNA expression profile help to identify novel targets for zoledronic acid in breast cancer?

artículo científico publicado en 2016

Circular RNA in Exosomes

artículo científico publicado en 2018

Conquests and perspectives of cardio-oncology in the field of tumor angiogenesis-targeting tyrosine kinase inhibitor-based therapy

artículo científico

Correction to: One shot NEPA plus dexamethasone to prevent chemotherapy-induced nausea and vomiting (CINV) in sarcoma patients receiving multiple-day chemotherapy

artículo científico publicado en 2019

Denosumab for bone health in prostate and breast cancer patients receiving endocrine therapy? A systematic review and a meta-analysis of randomized trials

artículo científico publicado en 2019

Detection of Germline Mutations in a Cohort of 139 Patients with Bilateral Breast Cancer by Multi-Gene Panel Testing: Impact of Pathogenic Variants in Other Genes beyond BRCA1/2

scientific article published on 25 August 2020

Dietary restriction: could it be considered as speed bump on tumor progression road?

artículo científico publicado en 2016

Driver mutations and differential sensitivity to targeted therapies: a new approach to the treatment of lung adenocarcinoma

artículo científico publicado en 2010

EGFR inhibition in NSCLC: New findings…. and opened questions?

artículo científico publicado en 2017

Effects of PPARγ agonists on the expression of leptin and vascular endothelial growth factor in breast cancer cells

artículo científico publicado en 2013

Effects of anti-miR-182 on TSP-1 expression in human colon cancer cells: there is a sense in antisense?

artículo científico

Expression of angiogenic regulators, VEGF and leptin, is regulated by the EGF/PI3K/STAT3 pathway in colorectal cancer cells.

artículo científico publicado en 2009

Farletuzumab for NSCLC: exploiting a well-known metabolic pathway for a new therapeutic strategy

artículo científico publicado en 2014

Genetic and molecular characterization of the human osteosarcoma 3AB-OS cancer stem cell line: a possible model for studying osteosarcoma origin and stemness.

artículo científico publicado en 2013

Germline copy number variation in the YTHDC2 gene: does it have a role in finding a novel potential molecular target involved in pancreatic adenocarcinoma susceptibility?

artículo científico publicado en 2014

HIF-1 is involved in the negative regulation of AURKA expression in breast cancer cell lines under hypoxic conditions

artículo científico publicado en 2013

Have p53 gene mutations and protein expression a different biological significance in colorectal cancer?

artículo científico publicado en 2002

HepatomiRNoma: The proposal of a new network of targets for diagnosis, prognosis and therapy in hepatocellular carcinoma

artículo científico publicado en 2015

Hereditary Breast and Ovarian Cancer in Families from Southern Italy (Sicily)-Prevalence and Geographic Distribution of Pathogenic Variants in BRCA1/2 Genes

artículo científico publicado en 2020

Hereditary ovarian cancer

scientific article published on 24 July 2008

Heterogeneity within and between primary colorectal carcinomas and matched metastases as revealed by analysis of Ki-ras and p53 mutations.

artículo científico publicado en 2004

How do skeletal morbidity rate and special toxicities affect 12-week versus 4-week schedule zoledronic acid efficacy? A systematic review and a meta-analysis of randomized trials

artículo científico publicado en 2019

How to Deal with Second Line Dilemma in Metastatic Colorectal Cancer? A Systematic Review and Meta-Analysis

artículo científico publicado en 2019

Hypoxia and human genome stability: downregulation of BRCA2 expression in breast cancer cell lines

artículo científico publicado en 2013

Immunotherapy for recurrent ovarian cancer: a further piece of the puzzle or a striking strategy?

artículo científico publicado en 2014

Impact of microRNAs in resistance to chemotherapy and novel targeted agents in non-small cell lung cancer.

artículo científico

Involvement of Non-coding RNAs in Chemo- and Radioresistance of Colorectal Cancer.

artículo científico publicado en 2016

Is BRCA1-5083del19, identified in breast cancer patients of Sicilian origin, a Calabrian founder mutation?

artículo científico publicado en 2008

Laser pressure catapulting (LPC): optimization LPC-system and genotyping of colorectal carcinomas.

artículo científico publicado en 2005

Male breast cancer

February 2010 review article in Critical Reviews in Oncology Hematology

Metastatic site location influences the diagnostic accuracy of ctDNA EGFR- mutation testing in NSCLC patients: a pooled analysis.

artículo científico publicado en 2018

Monoclonal antibodies and antibody fragments: state of the art and future perspectives in the treatment of non-haematological tumors

artículo científico publicado en 2011

Monoclonal antibodies for the treatment of non-haematological tumours: update of an expanding scenario.

artículo científico

Monoclonal antibodies for the treatment of non-hematological tumors: a safety review

scientific article published on 28 November 2018

Monoclonal antibodies in gastrointestinal cancers.

artículo científico

Moving the Target on the Optimal Adjuvant Strategy for Resected Pancreatic Cancers: A Systematic Review with Meta-Analysis

scientific article published on 26 February 2020

New findings on primary and acquired resistance to anti-EGFR therapy in metastatic colorectal cancer: do all roads lead to RAS?

artículo científico publicado en 2015

Nintedanib in NSCLC: evidence to date and place in therapy

artículo científico publicado en 2016

Nm23-H1 expression does not predict clinical survival in colorectal cancer patients

artículo científico publicado en 2003

Non-coding RNAs Functioning in Colorectal Cancer Stem Cells

artículo científico publicado en 2016

One shot NEPA plus dexamethasone to prevent multiple-day chemotherapy in sarcoma patients

scientific article published on 14 February 2019

PD-L1 expression as predictive biomarker in patients with NSCLC: a pooled analysis

artículo científico publicado en 2016

Pharmacogenomics in colorectal carcinomas: future perspectives in personalized therapy

artículo científico publicado en 2005

Prognostic and predictive biomarkers for targeted therapy in NSCLC: for whom the bell tolls?

artículo científico

Prognostic significance of p16INK4a alterations and 9p21 loss of heterozygosity in locally advanced laryngeal squamous cell carcinoma

scientific article published on 01 September 2002

Prognostic vs predictive molecular biomarkers in colorectal cancer: is KRAS and BRAF wild type status required for anti-EGFR therapy?

artículo científico publicado en 2010

Publisher Correction: The diagnostic accuracy of circulating tumor DNA for the detection of EGFR-T790M mutation in NSCLC: a systematic review and meta-analysis

scientific article published in Scientific Reports

Reply to: Denosumab for bone health in prostate and breast cancer patients receiving endocrine therapy? A systematic review and a meta-analysis of randomized trials (Galvano et al., J Bone Oncol 2019; 18:100252)

artículo científico publicado en 2020

Role of tumor-infiltrating lymphocytes in patients with solid tumors: Can a drop dig a stone?

artículo científico publicado en 2018

STAT proteins: From normal control of cellular events to tumorigenesis ⬇️

artículo científico publicado el 1 de noviembre de 2003

TP53 and p16INK4A, but not H-KI-Ras, are involved in tumorigenesis and progression of pleomorphic adenomas

artículo científico publicado en 2006

TP53 in gastric cancer: mutations in the l3 loop and LSH motif DNA-binding domains of TP53 predict poor outcome

artículo científico publicado en 2004

TP53 mutations and S-phase fraction but not DNA-ploidy are independent prognostic indicators in laryngeal squamous cell carcinoma

artículo científico publicado en 2006

Targeting apoptosis in solid tumors: the role of bortezomib from preclinical to clinical evidence.

artículo científico publicado en 2007

The TP53 colorectal cancer international collaborative study on the prognostic and predictive significance of p53 mutation: influence of tumor site, type of mutation, and adjuvant treatment

artículo científico publicado en 2005

The comparison of outcomes from tyrosine kinase inhibitor monotherapy in second- or third-line for advanced non-small-cell lung cancer patients with wild-type or unknown EGFR status

scientific article published on 16 March 2016

The diagnostic accuracy of circulating tumor DNA for the detection of EGFR-T790M mutation in NSCLC: a systematic review and meta-analysis

artículo científico publicado en 2018

The effects of enzalutamide and abiraterone on skeletal related events and bone radiological progression free survival in castration resistant prostate cancer patients: An indirect comparison of randomized controlled trials

artículo científico publicado en 2017

The long and winding road to useful predictive factors for anti-EGFR therapy in metastatic colorectal carcinoma: the KRAS/BRAF pathway

artículo científico publicado en 2009

The resistance related to targeted therapy in malignant pleural mesothelioma: Why has not the target been hit yet?

artículo científico publicado en 2016

The role of microRNAs in cancer: diagnostic and prognostic biomarkers and targets of therapies.

artículo científico

The significance of epidermal growth factor receptor uncommon mutations in non-small cell lung cancer: A systematic review and critical appraisal

artículo científico publicado en 2020

Triple negative breast cancer: shedding light onto the role of pi3k/akt/mtor pathway.

artículo científico publicado en 2016

What links BRAF to the heart function? New insights from the cardiotoxicity of BRAF inhibitors in cancer treatment

artículo científico publicado en 2015

miR-20b modulates VEGF expression by targeting HIF-1 alpha and STAT3 in MCF-7 breast cancer cells.

artículo científico publicado en 2010

p53 mutations in L3-loop zinc-binding domain, DNA-ploidy, and S phase fraction are independent prognostic indicators in colorectal cancer: a prospective study with a five-year follow-up.

artículo científico publicado en 2002

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