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"Lipidomics": Mass spectrometric and chemometric analyses of lipids

scientific article published on 14 June 2020

A Bifunctional Adsorber Particle for the Removal of Hydrophobic Uremic Toxins from Whole Blood of Renal Failure Patients

scientific article published on 03 July 2019

A bench to bedside view of uremic toxins

artículo científico publicado en 2008

A biomarker for severity of Alzheimer's disease: 1H-NMR resonances in cerebrospinal fluid correlate with performance in mini-mental-state-exam

artículo científico publicado en 2012

A possible new diagnostic biomarker in early diagnosis of Alzheimer's disease

artículo científico publicado en 2009

A urinary proteome-based classifier for the early detection of decline in glomerular filtration

artículo científico publicado en 2016

Absolute quantification of endogenous angiotensin II levels in human plasma using ESI-LC-MS/MS.

artículo científico publicado en 2014

Adenosine 5'-tetraphosphate is a highly potent purinergic endothelium-derived vasoconstrictor.

artículo científico publicado en 2008

Adsorption capacity of poly(ether imide) microparticles to uremic toxins

artículo científico publicado en 2015

Advances in urinary proteome analysis and biomarker discovery

artículo científico publicado en 2007

An in-vitro assay using human spermatozoa to detect toxicity of biologically active substances

artículo científico publicado en 2019

An optical method for serum calcium and phosphorus level assessment during hemodialysis

artículo científico publicado en 2015

Analysis of the releasable nucleotides of platelets

artículo científico publicado en 2004

Angioprotectin: an angiotensin II-like peptide causing vasodilatory effects

artículo científico publicado en 2011

Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation

scientific article published on 09 December 2019

Atheroprotective role of C5ar2 deficiency in apolipoprotein E-deficient mice

artículo científico publicado en 2015

Blockade of CCR3 retains the neutrophils, preserving their survival during healing after myocardial infarction

scientific article published on 30 June 2015

Blunted coronary vasodilator response to uridine adenosine tetraphosphate in post-infarct remodeled myocardium is due to reduced P1 receptor activation

article

Body fluid peptide and protein signatures in diabetic kidney diseases

artículo científico publicado en 2015

CE-MS analysis of the human urinary proteome for biomarker discovery and disease diagnostics

artículo científico publicado en 2008

CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4+ T-Cell-Dependent Control of Senescence

scientific article published on 30 January 2019

Carbamylated low-density lipoprotein induces endothelial dysfunction

artículo científico publicado en 2014

Cardiac FGF23: new insights into the role and function of FGF23 after acute myocardial infarction

artículo científico publicado en 2019

Cellular and Molecular Mechanisms of Chronic Kidney Disease with Diabetes Mellitus and Cardiovascular Diseases as Its Comorbidities

artículo científico publicado en 2015

Characterisation of advanced glycation endproducts in saliva from patients with diabetes mellitus

artículo científico publicado en 2004

Characterization of polymer membranes by MALDI mass-spectrometric imaging techniques

artículo científico publicado en 2013

Clinical proteomics: A need to define the field and to begin to set adequate standards

artículo científico publicado en 2007

Comparison of Depletion Strategies for the Enrichment of Low-Abundance Proteins in Urine

artículo científico publicado en 2015

Comparison of Urine and Plasma Peptidome Indicates Selectivity in Renal Peptide Handling

article by Pedro Magalhães et al published 23 April 2018 in Proteomics - Clinical Applications

Correction: Identification of a Potent Endothelium-Derived Angiogenic Factor.

artículo científico publicado en 2013

Detection of angiotensin II in supernatants of stimulated mononuclear leukocytes by matrix-assisted laser desorption ionization time-of-flight/time-of-flight mass analysis

artículo científico publicado en 2005

Detection of protease activities with the mass-spectrometry-assisted enzyme-screening (MES) system ⬇️

artículo científico publicado el 26 de septiembre de 2003

Development of In vitro endothelialized drug-eluting stent using human peripheral blood-derived endothelial progenitor cells

scientific article published on 15 July 2020

Development, establishment and validation of in vitro and ex vivo assays of vascular calcification

scientific article published on 16 June 2020

Diagnosis and Prediction of CKD Progression by Assessment of Urinary Peptides

artículo científico publicado en 2015

Differential Role for Activating FcγRIII in Neointima Formation After Arterial Injury and Diet-Induced Chronic Atherosclerosis in Apolipoprotein E-Deficient Mice

artículo científico publicado en 2020

Differential effects of uridine adenosine tetraphosphate on purinoceptors in the rat isolated perfused kidney.

artículo científico publicado en 2010

Diguanosine pentaphosphate: an endogenous activator of Rho-kinase possibly involved in blood pressure regulation

artículo científico publicado en 2006

Dinucleoside polyphosphates and uremia

artículo científico publicado en 2009

Dinucleoside polyphosphates: newly detected uraemic compounds with an impact on leucocyte oxidative burst

artículo científico publicado en 2010

Dinucleoside polyphosphates: strong endogenous agonists of the purinergic system.

artículo científico publicado en 2009

Dinucleotide polyphosphates contribute to purinergic signalling via inhibition of adenylate kinase activity

artículo científico publicado en 2008

Discovery and characterization of alamandine: a novel component of the renin-angiotensin system

artículo científico publicado en 2013

Does an apple a day put hypertension in play?

artículo científico publicado en 2008

Editorial on the Special Issue "Comorbidities in Chronic Kidney Disease"

artículo científico publicado en 2020

Effect of extracts of poly(ether imide) microparticles on cytotoxicity, ROS generation and proinflammatory effects on human monocytic (THP-1) cells

artículo científico publicado en 2015

Effects of dinucleoside polyphosphates on regulation of coronary vascular tone

artículo científico publicado en 2002

Effects of extracts prepared from modified porous poly(ether imide) microparticulate absorbers on cytotoxicity, macrophage differentiation and proinflammatory behavior of human monocytic (THP-1) cells.

artículo científico publicado en 2018

Emerging role of post-translational modifications in chronic kidney disease and cardiovascular disease.

artículo científico

Endogenous diadenosine tetraphosphate, diadenosine pentaphosphate, and diadenosine hexaphosphate in human myocardial tissue

artículo científico publicado en 2004

Endothelium and vascular smooth muscle cells in the context of uremia.

artículo científico publicado en 2009

Evaluation of the Zucker diabetic fatty (ZDF) rat as a model for human disease based on urinary peptidomic profiles

artículo científico publicado en 2012

FP279HIGH-RESOLUTION PLASMA PROTEOME ANALYSIS IDENTIFIES NEW CHANGES IN MOLECULAR MECHANISMS INVOLVED IN CHRONIC KIDNEY DISEASE

Gases as uremic toxins: is there something in the air?

artículo científico publicado en 2014

Glucagon-Like Peptide 1 and Its Cleavage Products Are Renoprotective in Murine Diabetic Nephropathy

artículo científico publicado en 2018

Golgin A4 in CSF and granulovacuolar degenerations of Alzheimer patients

article

Guanidino compounds as cause of cardiovascular damage in chronic kidney disease: an in vitro evaluation.

artículo científico publicado en 2010

High-density lipoprotein loses its anti-inflammatory capacity by accumulation of pro-inflammatory-serum amyloid A.

artículo científico publicado en 2012

Highly sensitive, selective and rapid LC-MS method for simultaneous quantification of diadenosine polyphosphates in human plasma

artículo científico publicado en 2014

Identification and characterization of adenosine 5'-tetraphosphate in human myocardial tissue.

artículo científico publicado en 2003

Identification and quantification of diadenosine polyphosphate concentrations in human plasma.

artículo científico publicado en 2003

Identification of a potent endothelium-derived angiogenic factor

artículo científico publicado en 2013

Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis

artículo científico publicado en 2017

Identification of the Vasoconstriction-Inhibiting Factor (VIF), a Potent Endogenous Cofactor of Angiotensin II Acting on the Angiotensin II Type 2 Receptor.

artículo científico publicado en 2015

Immunomodulator FTY720 Induces eNOS-dependent arterial vasodilatation via the lysophospholipid receptor S1P3.

artículo científico publicado en 2005

Impact of the uremic milieu on the osteogenic potential of mesenchymal stem cells

artículo científico publicado en 2015

Implementation of proteomic biomarkers: making it work

artículo científico publicado en 2012

Improving peptide relative quantification in MALDI-TOF MS for biomarker assessment

artículo científico publicado en 2013

Inconsistency of reported uremic toxin concentrations

artículo científico publicado en 2007

Increased uridine adenosine tetraphosphate concentrations in plasma of juvenile hypertensives.

artículo científico publicado en 2007

Induction of cerebral arteriogenesis leads to early-phase expression of protease inhibitors in growing collaterals of the brain

artículo científico publicado en 2008

Influence of nanoporous poly(ether imide) particle extracts on human aortic endothelial cells (HAECs).

artículo científico publicado en 2016

Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo.

artículo científico publicado en 2017

Interaction of human serum albumin with short polyelectrolytes: a study by calorimetry and computer simulations ⬇️

artículo científico publicado en 2015

Lipoproteins and lipids in cardiovascular disease: from mechanistic insights to therapeutic targeting

artículo científico publicado en 2020

Mass-spectrometric identification of a novel angiotensin peptide in human plasma.

artículo científico publicado en 2006

Measuring intradialyser transmembrane and hydrostatic pressures: pitfalls and relevance in haemodialysis and haemodiafiltration

artículo científico publicado en 2019

Mechanisms of cardiovascular complications in chronic kidney disease: research focus of the Transregional Research Consortium SFB TRR219 of the University Hospital Aachen (RWTH) and the Saarland University

artículo científico publicado en 2018

MicroRNAs in Chronic Kidney Disease: Four Candidates for Clinical Application

scientific article published on 07 September 2020

Mif-deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis.

artículo científico publicado en 2018

Minor Postoperative Increases of Creatinine Are Associated with Higher Mortality and Longer Hospital Length of Stay in Surgical Patients

artículo científico publicado en 2015

Modulation of NADPH oxidase activity by known uraemic retention solutes.

artículo científico publicado en 2014

Multicentre prospective validation of a urinary peptidome-based classifier for the diagnosis of type 2 diabetic nephropathy

artículo científico publicado en 2014

Native, Intact Glucagon-Like Peptide 1 Is a Natural Suppressor of Thrombus Growth Under Physiological Flow Conditions

artículo científico publicado en 2020

Naturally occurring human urinary peptides for use in diagnosis of chronic kidney disease

artículo científico publicado en 2010

Neutrophils Modulate Fibroblast Function and Promote Healing and Scar Formation after Murine Myocardial Infarction ⬇️

artículo científico publicado en 2020

New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis

artículo científico publicado en 2015

Non-activatable mutant of inhibitor of kappa B kinase α (IKKα) exerts vascular site-specific effects on atherosclerosis in Apoe-deficient mice

artículo científico publicado en 2019

Noninvasive diagnosis of chronic kidney diseases using urinary proteome analysis

artículo científico publicado en 2016

Normal and pathologic concentrations of uremic toxins ⬇️

artículo científico

Novel plasma peptide markers involved in the pathology of CKD identified using mass spectrometric approach

scientific article published on 05 August 2019

On the discovery of UREA. Identification, synthesis and observations that let to establishing the first uraemic retention solute

artículo científico publicado en 2016

Oxidative Stress in Chronic Kidney Disease

artículo científico publicado en 2016

Oxidized low-density lipoprotein in postmenopausal women

artículo científico publicado en 2014

PeptiCKDdb-peptide- and protein-centric database for the investigation of genesis and progression of chronic kidney disease

artículo científico publicado en 2016

Phenylacetic acid and arterial vascular properties in patients with chronic kidney disease stage 5 on hemodialysis therapy

scientific article published on 05 July 2007

Plasma proteomics classifiers improve risk prediction for renal disease in patients with hypertension or type 2 diabetes

artículo científico publicado en 2015

Platelet/Leukocyte activation, inflammation, and uremia

artículo científico publicado en 2009

Prediction of Chronic Kidney Disease Stage 3 by CKD273, a Urinary Proteomic Biomarker

artículo científico publicado en 2017

Principle and applications of the protein-purification-parameter screening system

artículo científico publicado en 2004

Prognostic clinical and molecular biomarkers of renal disease in type 2 diabetes

artículo científico

Proteomanalyse: Neue Wege zur verbesserten Behandlung der diabetischen Nephropathie

Proteomic Biomarkers to Guide Stratification for Covid-19 Treatment: Exemplifying a Path Forward Toward Implementation?

artículo científico publicado en 2020

Proteomic-Biostatistic Integrated Approach for Finding the Underlying Molecular Determinants of Hypertension in Human Plasma

artículo científico publicado en 2017

Proteomics in uremia and renal disease

artículo científico publicado en 2009

Proteomics of vitreous humor of patients with exudative age-related macular degeneration

artículo científico publicado en 2014

Recommendations for biomarker identification and qualification in clinical proteomics

artículo científico publicado en 2010

Reduced post-operative DPP4 activity associated with worse patient outcome after cardiac surgery

artículo científico publicado en 2018

Registration of Image Modalities for Analyses of Tissue Samples Using 3D Image Modelling

artículo científico publicado en 2020

Relationship between Magnesium and Clinical Biomarkers on Inhibition of Vascular Calcification ⬇️

artículo científico publicado el 15 de diciembre de 2011

Release of uremic retention solutes from protein binding by hypertonic predilution hemodiafiltration

artículo científico publicado en 2015

Removal of Protein‐Bound, Hydrophobic Uremic Toxins by a Combined Fractionated Plasma Separation and Adsorption Technique ⬇️

artículo científico publicado el 18 de enero de 2013

Review on uraemic toxins III: recommendations for handling uraemic retention solutes in vitro towards a standardized approach for research on uraemia

artículo científico publicado en 2007

Role of the CX3C chemokine receptor CX3CR1 in the pathogenesis of atherosclerosis after aortic transplantation

artículo científico publicado en 2017

Sample preparation of formalin-fixed paraffin-embedded tissue sections for MALDI-mass spectrometry imaging

scientific article published on 28 January 2020

Soluble vascular endothelial growth factor receptor-1 (sFLT-1) mediates downregulation of FLT-1 and prevents activated neutrophils from women with preeclampsia from additional migration by VEGF.

artículo científico publicado en 2005

Surface characterization of dialyzer polymer membranes by imaging ToF-SIMS and quantitative XPS line scans

artículo científico publicado en 2015

Targeting proinflammatory cytokines ameliorates calcifying phenotype conversion of vascular progenitors under uremic conditions in vitro

artículo científico publicado en 2018

The "artificial artery" as in vitro perfusion model

artículo científico publicado en 2013

The AN69 Hemofiltration Membrane Has a Decreasing Effect on the Intracellular Diadenosine Pentaphosphate Concentration of Platelets ⬇️

artículo científico publicado el 1 de enero de 2003

The Effect of Microgravity on Central Aortic Blood Pressure

The antioxidant acetylcysteine reduces cardiovascular events in patients with end-stage renal failure: a randomized, controlled trial

artículo científico publicado en 2003

The endothelium-derived contracting factor uridine adenosine tetraphosphate induces P2Y2-mediated pro-inflammatory signaling by monocyte chemoattractant protein-1 formation ⬇️

artículo científico publicado el 13 de abril de 2011

The enzymatic activity of the VEGFR2 receptor for the biosynthesis of dinucleoside polyphosphates

artículo científico publicado en 2013

The new SFB/TRR219 Research Centre.

artículo científico publicado en 2018

The role of EUTox in uremic toxin research

scientific article published on July 2009

The uraemic toxin phenylacetic acid impairs macrophage function.

artículo científico publicado en 2008

Up4A stimulates endothelium-independent contraction of isolated rat pulmonary artery

artículo científico publicado en 2008

Uremic Toxins Affecting Cardiovascular Calcification: A Systematic Review

scientific article published on 06 November 2020

Uremic Toxins and Ciprofloxacin Affect Human Tenocytes In Vitro

artículo científico publicado en 2020

Uremic toxins in acute kidney injury

artículo científico publicado en 2009

Uridine adenosine tetraphosphate (Up4A) is a strong inductor of smooth muscle cell migration via activation of the P2Y2 receptor and cross-communication to the PDGF receptor ⬇️

artículo científico publicado el 26 de diciembre de 2011

Uridine adenosine tetraphosphate activation of the purinergic receptor P2Y enhances in vitro vascular calcification

artículo científico publicado en 2011

Uridine adenosine tetraphosphate: a novel endothelium- derived vasoconstrictive factor

artículo científico publicado en 2005

Volatile Organic Compounds in Uremia ⬇️

artículo científico publicado el 25 de septiembre de 2012

α-1-Antitrypsin detected by MALDI imaging in the study of glomerulonephritis: Its relevance in chronic kidney disease progression

artículo científico publicado en 2016

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