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A JAK2/IDH1-mutant MPN clone unmasked by ivosidenib in an AML patient without antecedent MPN

artículo científico publicado en 2020

Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins

scientific article published on 14 June 2018

Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S

artículo científico publicado en 2014

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

artículo científico publicado en 2013

Clonal Hematopoiesis and Evolution to Hematopoietic Malignancies

artículo científico publicado en 2018

Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation

scientific article published on 05 September 2019

Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer

artículo científico publicado en 2016

Deconvoluting hepatic processing of carbon nanotubes

scientific article published on 29 July 2016

Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance

artículo científico publicado en 2020

Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers.

artículo científico publicado en 2017

Evaluating Clonal Hematopoiesis in Tumor-Infiltrating Leukocytes in Breast Cancer and Secondary Hematologic Malignancies

artículo científico publicado en 2020

Evolution of Cancer Stem-like Cells in Endocrine-Resistant Metastatic Breast Cancers Is Mediated by Stromal Microvesicles.

artículo científico publicado en 2017

Genetic and epigenetic evolution as a contributor to WT1-mutant leukemogenesis

artículo científico publicado en 2018

GlioVis data portal for visualization and analysis of brain tumor expression datasets

artículo científico publicado en 2016

Human iPSC-based modeling of late-onset disease via progerin-induced aging

artículo científico publicado en 2013

Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells

artículo científico publicado en 2020

Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis.

artículo científico publicado en 2017

Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis.

artículo científico publicado en 2018

Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies

artículo científico publicado en 2016

Microenvironment-derived factors driving metastatic plasticity in melanoma.

artículo científico publicado en 2017

Microglia promote glioblastoma via mTOR-mediated immunosuppression of the tumour microenvironment

scientific article published on 22 June 2020

PRMT5 inhibition modulates E2F1 methylation and gene regulatory networks leading to therapeutic efficacy in JAK2V617F mutant MPN

artículo científico publicado en 2020

Plasmacytoid dendritic cell expansion defines a distinct subset of RUNX1 mutated acute myeloid leukemia

scientific article published on 01 September 2020

STAT3 and STAT6 Signaling Pathways Synergize to Promote Cathepsin Secretion from Macrophages via IRE1α Activation

artículo científico publicado en 2016

Self-renewal of CD133(hi) cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer

artículo científico publicado en 2016

Single-cell mutation analysis of clonal evolution in myeloid malignancies

artículo científico publicado en 2020

TET2 in Normal and Malignant Hematopoiesis

artículo científico publicado en 2017

The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas

artículo científico publicado en 2016

Therapeutic targeting of tumor-associated macrophages and microglia in glioblastoma

artículo científico publicado en 2014

Underlying Causes and Therapeutic Targeting of the Inflammatory Tumor Microenvironment

artículo científico publicado en 2018

eIF2α kinases control chalone production in Dictyostelium discoideum

artículo científico publicado en 2011