Lista de obras -

A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.

artículo científico publicado en 2018

A short segment of the HIV-1 gp120 V1/V2 region is a major determinant of resistance to V1/V2 neutralizing antibodies

artículo científico publicado en 2012

Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

artículo científico publicado en 2011

Author Correction: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite

artículo científico publicado en 2019

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

artículo científico publicado en 2014

Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: antigenicity, biophysics, and immunogenicity ⬇️

artículo científico publicado en 2007

Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1

artículo científico publicado en 2011

Crystal Structure of PG16 and Chimeric Dissection with Somatically Related PG9: Structure-Function Analysis of Two Quaternary-Specific Antibodies That Effectively Neutralize HIV-1

artículo científico publicado en 2010

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

artículo científico publicado en 2015

Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.

artículo científico publicado en 2017

Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization

artículo científico publicado en 2013

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

artículo científico publicado en 2014

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

artículo científico publicado en 2016

Immunogenicity of a Prefusion HIV-1 Envelope Trimer in Complex with a Quaternary-Structure-Specific Antibody

artículo científico publicado en 2015

Immunotypes of a quaternary site of HIV-1 vulnerability and their recognition by antibodies

artículo científico publicado en 2011

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.

scientific article published on August 2016

Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.

artículo científico publicado en 2017

Mining the antibodyome for HIV-1-neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains

artículo científico publicado en 2013

N332-Directed broadly neutralizing antibodies use diverse modes of HIV-1 recognition: inferences from heavy-light chain complementation of function

artículo científico publicado en 2013

New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

artículo científico publicado en 2015

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation

artículo científico publicado en 2017

Residue-level prediction of HIV-1 antibody epitopes based on neutralization of diverse viral strains

artículo científico publicado en 2013

Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env.

artículo científico publicado en 2015

Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains

artículo científico publicado en 2017

Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

artículo científico publicado en 2013

Somatic Populations of PGT135-137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics

artículo científico publicado en 2012

Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

artículo científico publicado en 2009

Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection

artículo científico publicado en 2014

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

artículo científico publicado en 2015

Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

artículo científico publicado en 2013

Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation

scientific article published on 27 October 2020

Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit

artículo científico publicado en 2022

Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

artículo científico publicado en 2014

Structure of BMS-806, a Small-molecule HIV-1 Entry Inhibitor, Bound to BG505 SOSIP.664 HIV-1 Env Trimer.

artículo científico publicado en 2014

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

artículo científico publicado en 2011

Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility

artículo científico publicado en 2010

Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity

artículo científico publicado en 2017

Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

artículo científico publicado en 2016

Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody

artículo científico publicado en 2018

Transient Protein Expression Facilitates X-ray Structural Studies of HIV-1.

artículo científico publicado en 2014

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

artículo científico publicado en 2016

Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens.

artículo científico publicado en 2018

Uncleaved Soluble gp140 Constructs with Retained Native-like Trimer Conformation and Antigenicity.

artículo científico publicado en 2014

V1/V2 Neutralizing Epitope is Conserved in Divergent Non-M Groups of HIV-1

artículo científico publicado en 2015

Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability

scientific article published on 12 November 2019

Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

artículo científico publicado en 2013

Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop

artículo científico publicado en 2017

Lista de obras de

A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.

A short segment of the HIV-1 gp120 V1/V2 region is a major determinant of resistance to V1/V2 neutralizing antibodies

Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

Author Correction: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: antigenicity, biophysics, and immunogenicity ⬇️

Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1

Crystal Structure of PG16 and Chimeric Dissection with Somatically Related PG9: Structure-Function Analysis of Two Quaternary-Specific Antibodies That Effectively Neutralize HIV-1

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.

Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

Immunogenicity of a Prefusion HIV-1 Envelope Trimer in Complex with a Quaternary-Structure-Specific Antibody

Immunotypes of a quaternary site of HIV-1 vulnerability and their recognition by antibodies

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.

Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.

Mining the antibodyome for HIV-1-neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains

N332-Directed broadly neutralizing antibodies use diverse modes of HIV-1 recognition: inferences from heavy-light chain complementation of function

New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation

Residue-level prediction of HIV-1 antibody epitopes based on neutralization of diverse viral strains

Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env.

Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains

Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

Somatic Populations of PGT135-137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics

Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation

Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit

Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

Structure of BMS-806, a Small-molecule HIV-1 Entry Inhibitor, Bound to BG505 SOSIP.664 HIV-1 Env Trimer.

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility

Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity

Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody

Transient Protein Expression Facilitates X-ray Structural Studies of HIV-1.

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens.

Uncleaved Soluble gp140 Constructs with Retained Native-like Trimer Conformation and Antigenicity.

V1/V2 Neutralizing Epitope is Conserved in Divergent Non-M Groups of HIV-1

Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability

Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop