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Activation of gamma delta T cells by Borrelia burgdorferi is indirect via a TLR- and caspase-dependent pathway

artículo científico publicado en 2008

Activation of the p38 mitogen-activated protein kinase pathway arrests cell cycle progression and differentiation of immature thymocytes in vivo

artículo científico publicado en 2000

Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity

artículo científico publicado en 2008

Apoptosis regulators Fas and Bim synergistically control T-lymphocyte homeostatic proliferation

artículo científico publicado en 2010

Cellular FLIP long form augments caspase activity and death of T cells through heterodimerization with and activation of caspase-8.

artículo científico publicado en 2005

Cellular FLIP long form-transgenic mice manifest a Th2 cytokine bias and enhanced allergic airway inflammation

artículo científico publicado en 2004

Conference highlight: do T cells care about the mitogen-activated protein kinase signalling pathways?

artículo científico publicado en 2000

Down-modulation of CD2 delays deletion of superantigen-responsive T cells

artículo científico publicado el 1 de enero de 1998

Fas (CD95/APO-1) limits the expansion of T lymphocytes in an environment of limited T-cell antigen receptor/MHC contacts

artículo científico publicado el 25 de enero de 2011

Fas ligand deficiency impairs host inflammatory response against infection with the spirochete Borrelia burgdorferi

artículo científico publicado en 2006

Fine-Tuning of CD8(+) T Cell Mitochondrial Metabolism by the Respiratory Chain Repressor MCJ Dictates Protection to Influenza Virus

artículo científico publicado en 2016

Glycolysis Induces MCJ Expression That Links T Cell Proliferation With Caspase-3 Activity and Death

Glycolysis promotes caspase-3 activation in lipid rafts in T cells

artículo científico publicado en 2018

IL-15 maintains T-cell survival via S-nitrosylation-mediated inhibition of caspase-3

artículo científico publicado en 2014

IL-6 promotes the differentiation of a subset of naive CD8+ T cells into IL-21-producing B helper CD8+ T cells.

scientific article published on 26 September 2016

Increased caspase activity primes human Lyme arthritis synovial γδ T cells for proliferation and death

artículo científico publicado el 22 de septiembre de 2011

JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells

artículo científico publicado en 1996

MCJ/DnaJC15, an endogenous mitochondrial repressor of the respiratory chain that controls metabolic alterations

scientific journal article

Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance

artículo científico publicado en 2021

Necroptosis of Dendritic Cells Promotes Activation of γδ T Cells.

artículo científico publicado en 2016

Proliferating γδ T cells manifest high and spatially confined caspase‐3 activity

artículo científico publicado el 1 de abril de 2012

Protein disulfide isomerase-endoplasmic reticulum resident protein 57 regulates allergen-induced airways inflammation, fibrosis, and hyperresponsiveness

artículo científico publicado en 2015

Reduced immune response to Borrelia burgdorferi in the absence of γδ T cells.

artículo científico publicado en 2011

Selective DNA Demethylation Accompanies T Cell Homeostatic Proliferation and Gene Regulation in Lupus-Prone lpr Mice

artículo científico publicado en 2020

Serum amyloid A inhibits dendritic cell apoptosis to induce glucocorticoid resistance in CD4(+) T cells

artículo científico publicado en 2013

Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation

artículo científico publicado en 2020

Sonoporation as an Approach for siRNA delivery into T cells

scientific article published on 17 September 2019

Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL-lpr mice

scientific article published on 16 April 2020

The c-FLIPL cleavage product p43FLIP promotes activation of extracellular signal-regulated kinase (ERK), nuclear factor κB (NF-κB), and caspase-8 and T cell survival

artículo científico publicado en 2013

The caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes

artículo científico publicado en 2002

The death receptor Fas (CD95/APO-1) mediates the deletion of T lymphocytes undergoing homeostatic proliferation.

artículo científico publicado en 2005

The molecular signature of murine T cell homeostatic proliferation reveals both inflammatory and immune inhibition patterns

artículo científico publicado en 2017

c-FLIP(S) reduces activation of caspase and NF-kappaB pathways and decreases T cell survival

artículo científico publicado en 2008