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A NOVEL NEUROIMAGING APPROACH TO CAPTURE COGNITIVE RESERVE

A NOVEL NEUROIMAGING APPROACH TO CAPTURE COGNITIVE RESERVE

A neuroimaging approach to capture cognitive reserve: Application to Alzheimer's disease

artículo científico publicado en 2017

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

article by Sven J. van der Lee et al published 27 May 2019 in Acta Neuropathologica

A novel partial volume correction method for accurate quantification of [F] flortaucipir in the hippocampus

ATN classification and clinical progression in subjective cognitive decline: The SCIENCe project

artículo científico publicado en 2020

Accuracy of 3-dimensional reconstruction algorithms for the high-resolution research tomograph

artículo científico publicado en 2008

Alzheimer's biomarkers in daily practice (ABIDE) project: Rationale and design

artículo científico publicado en 2017

Amyloid and its association with default network integrity in Alzheimer's disease

artículo científico publicado en 2012

Amyloid burden and metabolic function in early-onset Alzheimer's disease: parietal lobe involvement

artículo científico publicado en 2012

Amyloid-β PET and CSF in an autopsy-confirmed cohort

artículo científico publicado en 2020

An exploratory clinical study of p38α kinase inhibition in Alzheimer's disease.

artículo científico publicado en 2018

Application of Machine Learning to Arterial Spin Labeling in Mild Cognitive Impairment and Alzheimer Disease.

artículo científico publicado en 2016

Applying the ATN scheme in a memory clinic population: The ABIDE project

scientific article published on 09 October 2019

Arterial spin labeling perfusion MRI at multiple delay times: a correlative study with H(2)(15)O positron emission tomography in patients with symptomatic carotid artery occlusion.

artículo científico publicado en 2009

Assessing Amyloid Pathology in Cognitively Normal Subjects using [F]Flutemetamol PET: Comparing Visual Reads and Quantitative Methods

scholarly article by Lyduine Collij et al published 12 October 2018 in The Journal of Nuclear Medicine

Assessment of the appropriate use criteria for amyloid PET in an unselected memory clinic cohort: The ABIDE project

scientific article published on 06 October 2019

Association of Amyloid Positron Emission Tomography With Changes in Diagnosis and Patient Treatment in an Unselected Memory Clinic Cohort: The ABIDE Project

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

artículo científico publicado en 2017

Association of amyloid pathology with memory performance and cognitive complaints in cognitively normal older adults: a monozygotic twin study

artículo científico publicado en 2019

Associations between quantitative [18F]flortaucipir tau PET and atrophy across the Alzheimer's disease spectrum

scientific article published on 04 July 2019

Atrophy patterns in early clinical stages across distinct phenotypes of Alzheimer's disease

artículo científico publicado en 2015

Atrophy, hypometabolism and clinical trajectories in patients with amyloid-negative Alzheimer's disease.

artículo científico publicado en 2016

Blood-brain barrier P-glycoprotein function in Alzheimer's disease

artículo científico publicado en 2011

Blood-brain barrier P-glycoprotein function in healthy subjects and Alzheimer's disease patients: effect of polymorphisms in the ABCB1 gene

artículo científico publicado en 2012

Brain network alterations in Alzheimer's disease measured by eigenvector centrality in fMRI are related to cognition and CSF biomarkers

artículo científico publicado en 2013

Brain network alterations in Alzheimer's disease measured by eigenvector centrality in fMRI are related to cognition and CSF biomarkers

scholarly article by Maja Binnewijzend et al published July 2013 in Alzheimer's and Dementia

Brain network alterations in Alzheimer's disease measured by eigenvector centrality in fMRI are related to cognition and cerebrospinal fluid biomarkers

scholarly article by Maja Binnewijzend et al published July 2013 in Alzheimer's and Dementia

Building a new paradigm for the early recognition of behavioral variant frontotemporal dementia: Late Onset Frontal Lobe Syndrome study

artículo científico publicado en 2013

Cerebral blood flow measured with 3D pseudocontinuous arterial spin-labeling MR imaging in Alzheimer disease and mild cognitive impairment: a marker for disease severity

artículo científico publicado en 2012

Cerebral perfusion and glucose metabolism in Alzheimer's disease and frontotemporal dementia: two sides of the same coin?

artículo científico publicado en 2015

Cerebral perfusion in the predementia stages of Alzheimer's disease

artículo científico publicado en 2015

Clinical phenotype, atrophy, and small vessel disease in ε2 carriers with Alzheimer disease

artículo científico publicado en 2018

Combination of plasma amyloid beta(1-42/1-40) and glial fibrillary acidic protein strongly associates with cerebral amyloid pathology

artículo científico publicado en 2020

Comparison of 3D-OP-OSEM and 3D-FBP reconstruction algorithms for High-Resolution Research Tomograph studies: effects of randoms estimation methods

artículo científico publicado en 2008

Comparison of HRRT and HR+ scanners for quantitative (R)-[11C]verapamil, [11C]raclopride and [11C]flumazenil brain studies

artículo científico publicado en 2015

Comparison of oxygen-15 PET and transcranial Doppler CO2-reactivity measurements in identifying haemodynamic compromise in patients with symptomatic occlusion of the internal carotid artery

artículo científico publicado en 2012

Comparison of simplified parametric methods for visual interpretation of 11C-Pittsburgh compound-B PET images

artículo científico publicado en 2014

Concordance between cerebrospinal fluid biomarkers and [11C]PIB PET in a memory clinic cohort

artículo científico publicado en 2014

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

scientific article published on 18 January 2020

Day-to-day test-retest variability of CBF, CMRO2, and OEF measurements using dynamic 15O PET studies.

artículo científico publicado en 2011

Delta 9-tetrahydrocannabinol induces dopamine release in the human striatum

artículo científico publicado en 2008

Dementia mimicking Alzheimer's disease Owing to a tau mutation: CSF and PET findings

artículo científico publicado en 2010

Design of the NL-ENIGMA study: Exploring the effect of Souvenaid on cerebral glucose metabolism in early Alzheimer's disease

artículo científico publicado en 2016

Detection of Alzheimer pathology in vivo using both 11C-PIB and 18F-FDDNP PET.

artículo científico publicado en 2009

Development of a tracer kinetic plasma input model for (R)-[11C]PK11195 brain studies

artículo científico publicado en 2005

Diagnostic Accuracy of MRI and Additional [18F]FDG-PET for Behavioral Variant Frontotemporal Dementia in Patients with Late Onset Behavioral Changes

artículo científico publicado en 2016

Diagnostic Accuracy of the Frontotemporal Dementia Consensus Criteria in the Late-Onset Frontal Lobe Syndrome

artículo científico publicado en 2016

Diagnostic impact of [18F]flutemetamol PET in early-onset dementia

artículo científico publicado en 2017

Differential effect of APOE genotype on amyloid load and glucose metabolism in AD dementia

artículo científico publicado en 2012

Differential effects of cognitive reserve and brain reserve on cognition in Alzheimer disease

artículo científico publicado en 2017

Distinct perfusion patterns in Alzheimer's disease, frontotemporal dementia and dementia with Lewy bodies

artículo científico publicado en 2014

Dopaminergic activity in Tourette syndrome and obsessive-compulsive disorder

artículo científico publicado en 2013

Early diagnosis of Alzheimer disease: the role of Positron Emission Tomography (PET)

artículo científico publicado en 2013

Evaluation of methods for generating parametric (R-[11C]PK11195 binding images

artículo científico publicado en 2007

Evaluation of reference regions for (R)-[(11)C]PK11195 studies in Alzheimer's disease and mild cognitive impairment.

artículo científico publicado en 2007

Evaluation of reference tissue models for the analysis of [11C](R)-PK11195 studies

artículo científico publicado en 2006

Evaluation of tracer kinetic models for analysis of [18F]FDDNP studies

artículo científico publicado en 2009

Evaluation of tracer kinetic models for quantification of P-glycoprotein function using (R)-[11C]verapamil and PET.

artículo científico publicado en 2006

First evaluation of [11C]R116301 as an in vivo tracer of NK1 receptors in man

artículo científico publicado en 2009

First in human evaluation of [F]PK-209, a PET ligand for the ion channel binding site of NMDA receptors

Gap filling strategies for 3-D-FBP reconstructions of High-Resolution Research Tomograph scans

artículo científico publicado en 2008

HRRT versus HR+ human brain PET studies: an interscanner test-retest study

artículo científico publicado en 2009

Heterogeneous Language Profiles in Patients with Primary Progressive Aphasia due to Alzheimer's Disease

artículo científico publicado en 2016

Hypometabolism of the posterior cingulate cortex is not restricted to Alzheimer's disease.

artículo científico publicado en 2018

Image derived input functions for dynamic High Resolution Research Tomograph PET brain studies

artículo científico publicado en 2008

Image-derived input functions for PET brain studies

artículo científico publicado en 2008

Impact of Imaging and Cerebrospinal Fluid Biomarkers on Behavioral Variant Frontotemporal Dementia Diagnosis within a Late-Onset Frontal Lobe Syndrome Cohort.

artículo científico publicado en 2015

Impact of New Scatter Correction Strategies on High-Resolution Research Tomograph Brain PET Studies

artículo científico publicado en 2016

Impact of attenuation correction strategies on the quantification of High Resolution Research Tomograph PET studies

artículo científico publicado en 2007

Impact of molecular imaging on the diagnostic process in a memory clinic

artículo científico publicado en 2012

Impact of wavelet based denoising of [11C](R)-PK11195 time activity curves on accuracy and precision of kinetic analysis.

artículo científico publicado en 2008

In vivo quantification of striatal dopamine D2 receptor occupancy by JNJ-37822681 using [11C]raclopride and positron emission tomography

artículo científico publicado en 2012

In vivo validation of reconstruction-based resolution recovery for human brain studies

artículo científico publicado en 2009

Increased cerebral (R)-[(11)C]PK11195 uptake and glutamate release in a rat model of traumatic brain injury: a longitudinal pilot study

artículo científico publicado en 2011

Intervention versus standard medical treatment in patients with symptomatic occlusion of the internal carotid artery: a randomised oxygen-15 PET study

artículo científico publicado en 2013

Is retinal vasculature a biomarker in amyloid proven Alzheimer's disease?

artículo científico publicado en 2019

Long-term effects of amyloid, hypometabolism, and atrophy on neuropsychological functions

artículo científico publicado en 2014

Longitudinal amyloid imaging using 11C-PiB: methodologic considerations

artículo científico publicado en 2013

Longitudinal imaging of Alzheimer pathology using [11C]PIB, [18F]FDDNP and [18F]FDG PET.

artículo científico publicado en 2012

Microglia activation in recent-onset schizophrenia: a quantitative (R)-[11C]PK11195 positron emission tomography study.

artículo científico publicado en 2008

Microglial activation in Alzheimer's disease: an (R)-[¹¹C]PK11195 positron emission tomography study

artículo científico publicado en 2012

Microglial activation in healthy aging

Mild cognitive impairment with suspected nonamyloid pathology (SNAP): Prediction of progression

artículo científico publicado en 2015

Model selection criteria for dynamic brain PET studies

artículo científico publicado en 2017

Molecular imaging in the diagnosis of Alzheimer's disease: visual assessment of [11C]PIB and [18F]FDDNP PET images

artículo científico publicado en 2010

Molecular markers of Alzheimer's Disease pathology and their relationship with default mode network integrity

scholarly article by Sofie Adriaanse et al published July 2011 in Alzheimer's and Dementia

Multi-tracer model for staging cortical amyloid deposition using PET imaging

artículo científico publicado en 2020

No evidence for additional blood-brain barrier P-glycoprotein dysfunction in Alzheimer's disease patients with microbleeds

artículo científico publicado en 2012

Nutritional status and structural brain changes in Alzheimer's disease: The NUDAD project

artículo científico publicado en 2020

Optimization of supervised cluster analysis for extracting reference tissue input curves in (R)-[(11)C]PK11195 brain PET studies

artículo científico publicado en 2012

Optimizing an online SPE–HPLC method for analysis of (R)-[11C]1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide [(R)-[11C]PK11195] and its metabolites in humans

artículo científico publicado en 2005

Optimizing patient care and research: the Amsterdam Dementia Cohort

artículo científico publicado en 2014

P-glycoprotein function at the blood-brain barrier: effects of age and gender

artículo científico publicado en 2012

Parametric Binding Images of the TSPO Ligand 18F-DPA-714.

artículo científico publicado en 2016

Parametric methods for [18F]flortaucipir PET

scientific article published on 20 December 2018

Partial volume correction of brain PET studies using iterative deconvolution in combination with HYPR denoising

artículo científico publicado en 2017

Peripheral metabolism of [(18)F]FDDNP and cerebral uptake of its labelled metabolites

artículo científico publicado en 2008

Plasma Amyloid as Prescreener for the Earliest Alzheimer Pathological Changes

artículo científico publicado en 2018

Preclinical evaluation of [(18)F]PK-209, a new PET ligand for imaging the ion-channel site of NMDA receptors

artículo científico publicado en 2014

Prediction of AD dementia by biomarkers following the NIA-AA and IWG diagnostic criteria in MCI patients from three European memory clinics

artículo científico publicado en 2015

Prediction of dementia in MCI patients based on core diagnostic markers for Alzheimer disease

artículo científico publicado en 2013

Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage

artículo científico publicado en 2015

Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis

artículo científico publicado en 2015

Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia

artículo científico publicado en 2018

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

artículo científico publicado en 2015

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.

artículo científico publicado en 2018

Prognostic value of Alzheimer's biomarkers in mild cognitive impairment: the effect of age at onset

artículo científico publicado en 2019

Quantification of 11C-Laniquidar Kinetics in the Brain

artículo científico publicado en 2015

Quantification of Tau Load Using [(18)F]AV1451 PET.

artículo científico publicado en 2017

Quantification of [18F]DPA-714 binding in the human brain: initial studies in healthy controls and Alzheimer's disease patients

artículo científico publicado en 2015

Quantification of [18F]florbetapir: A test–retest tracer kinetic modelling study

artículo científico publicado en 2018

Quantification of dopamine transporter binding using [18F]FP-beta-CIT and positron emission tomography

artículo científico publicado en 2006

Quantification of the neurokinin 1 receptor ligand [11C]R116301

artículo científico publicado en 2011

Quantification of the novel N-methyl-d-aspartate receptor ligand [11C]GMOM in man

artículo científico publicado en 2015

Quantitative PET and Histology of Brain Biopsy Reveal Lack of Selective Pittsburgh Compound-B Binding to Intracerebral Amyloidoma

artículo científico publicado en 2018

Reference tissue models and blood-brain barrier disruption: lessons from (R)-[11C]PK11195 in traumatic brain injury

artículo científico publicado en 2009

Regional functional connectivity changes in AD and MCI: dual regression applied to resting state fMRI

Relationship of cerebrospinal fluid markers to 11C-PiB and 18F-FDDNP binding

artículo científico publicado en 2009

Reproducibility of quantitative (R)-[11C]verapamil studies

artículo científico publicado en 2012

Resilience to cognitive impairment in the oldest-old: design of the EMIF-AD 90+ study

Resting-state fMRI changes in Alzheimer's disease and mild cognitive impairment

artículo científico publicado en 2011

Retinal thickness as a potential biomarker in patients with amyloid-proven early- and late-onset Alzheimer's disease.

artículo científico publicado en 2019

SPM analysis of parametric (R)-[11C]PK11195 binding images: plasma input versus reference tissue parametric methods

artículo científico publicado en 2007

Secondary prevention of Alzheimer's dementia: neuroimaging contributions

artículo científico publicado en 2018

Semi-quantitative cerebral blood flow parameters derived from non-invasive [(15)O]H2O PET studies.

artículo científico publicado en 2017

Simplified parametric methods for [11C]PIB studies

artículo científico publicado en 2008

Simplified parametric methods for [18F]FDDNP studies.

artículo científico publicado en 2009

Subjective Cognitive Impairment Cohort (SCIENCe): study design and first results

Synthesis and preclinical evaluation of carbon-11 labelled N-((5-(4-fluoro-2-[(11)C]methoxyphenyl)pyridin-3-yl)methyl)cyclopentanamine as a PET tracer for NR2B subunit-containing NMDA receptors

artículo científico publicado en 2014

Synthesis, structure activity relationship, radiolabeling and preclinical evaluation of high affinity ligands for the ion channel of the N-methyl-d-aspartate receptor as potential imaging probes for positron emission tomography

artículo científico publicado en 2014

Test-retest variability of quantitative [11C]PIB studies in Alzheimer's disease

artículo científico publicado en 2009

The Association of Glucose Metabolism and Eigenvector Centrality in Alzheimer's Disease

artículo científico publicado en 2015

The EMIF-AD PreclinAD study: study design and baseline cohort overview

article by Elles Konijnenberg et al published 4 August 2018 in Alzheimers Research & Therapy

The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features

artículo científico publicado en 2015

The dopamine stabilizer (-)-OSU6162 occupies a subpopulation of striatal dopamine D2/D3 receptors: an [(11)C]raclopride PET study in healthy human subjects

artículo científico publicado en 2014

The effect of amyloid pathology and glucose metabolism on cortical volume loss over time in Alzheimer's disease

artículo científico publicado en 2014

The frequency and influence of dementia risk factors in prodromal Alzheimer's disease

artículo científico publicado en 2017

Unbiased Approach to Counteract Upward Drift in Cerebrospinal Fluid Amyloid-β 1-42 Analysis Results

artículo científico publicado en 2017

What determines cognitive functioning in the oldest-old? The EMIF-AD 90+ Study

artículo científico publicado en 2020

White matter microstructure disruption in early stage amyloid pathology

artículo científico publicado en 2021

Widespread and prolonged increase in (R)-(11)C-PK11195 binding after traumatic brain injury

artículo científico publicado en 2011

Widespread disruption of functional brain organization in early-onset Alzheimer's disease

artículo científico publicado en 2014

Widespread disruption of functional brain organization in early-onset Alzheimer's disease patients

Widespread disruption of functional brain organization in people with early-onset Alzheimer's disease