Lista de obras -

3D and 4D imaging of immune cells in vitro and in vivo

artículo científico publicado en 2008

A homogeneous 384-well high-throughput binding assay for a TNF receptor using alphascreen technology

artículo científico publicado en 2003

A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis

scientific article published on 09 April 2009

A specific anti-citrullinated protein antibody profile identifies a group of rheumatoid arthritis patients with a toll-like receptor 4-mediated disease

artículo científico publicado en 2016

Antibody Neutralization of CXCL10 in Vivo Is Dependent on Binding to Free and Not Endothelial-bound Chemokine: IMPLICATIONS FOR THE DESIGN OF A NEW GENERATION OF ANTI-CHEMOKINE THERAPEUTIC ANTIBODIES.

artículo científico publicado en 2017

CC chemokine CCL5 plays a central role impacting infarct size and post-infarction heart failure in mice

artículo científico publicado en 2011

Characterization of a surrogate murine antibody to model anti-human CD3 therapies

artículo científico publicado en 2013

Chemokines derived from soluble fusion proteins expressed in Escherichia coli are biologically active

artículo científico publicado en 2005

Co-engaging CD47 and CD19 with a bispecific antibody abrogates B-cell receptor/CD19 association leading to impaired B-cell proliferation

artículo científico publicado en 2019

Combination therapies in the context of anti-CD3 antibodies for the treatment of autoimmune diseases

artículo científico publicado en 2012

Comparing CDRH3 diversity captured from secondary lymphoid organs for the generation of recombinant human antibodies

artículo científico publicado en 2013

Constitutive activation of epithelial TLR4 augments inflammatory responses to mucosal injury and drives colitis-associated tumorigenesis

artículo científico publicado en 2011

De novo isolation of antibodies with pH-dependent binding properties

Deep sequencing of phage display libraries to support antibody discovery

artículo científico publicado en 2013

Deriving a germinal center lymphocyte migration model from two-photon data

artículo científico publicado en 2008

Dual display: phage selection driven by co-engagement of two targets by two different antibody fragments

artículo científico publicado en 2017

Effect of Toll-like receptor 4 blockade on pulmonary inflammation caused by mechanical ventilation and bacterial endotoxin

artículo científico publicado en 2008

Enhancement of islet engraftment and achievement of long-term islet allograft survival by Toll-like receptor 4 blockade.

artículo científico publicado en 2015

Epitope-dependent inhibition of T cell activation by the Ea transgene: an explanation for transgene-mediated protection from murine lupus

scientific article published on 01 August 2004

Exploiting light chains for the scalable generation and platform purification of native human bispecific IgG.

artículo científico publicado en 2015

Germinal center B cells govern their own fate via antibody feedback

artículo científico publicado en 2013

IL-17F co-expression improves cell growth characteristics and enhances recombinant protein production during CHO cell line engineering

artículo científico publicado en 2012

Inhibition of airway inflammation by amino-terminally modified RANTES/CC chemokine ligand 5 analogues is not mediated through CCR3.

artículo científico publicado en 2003

Interferon gamma (IFNg) production is associated to disease parameters in TLR9-induced secondary hemophagocytic lymphohistiocytosis (sHLH) in mice.

artículo científico publicado en 2014

Long‐term amelioration of established collagen‐induced arthritis achieved with short‐term therapy combining anti‐CD3 and anti–tumor necrosis factor treatments ⬇️

artículo científico publicado el 1 de octubre de 2012

Maximizing the potency of an anti-TLR4 monoclonal antibody by exploiting proximity to Fcγ receptors

artículo científico publicado en 2014

Neutralization of IFNgamma defeats haemophagocytosis in LCMV-infected perforin- and Rab27a-deficient mice

artículo científico publicado en 2009

Novel Insights into Interleukin 6 (IL-6) Cis- and Trans-signaling Pathways by Differentially Manipulating the Assembly of the IL-6 Signaling Complex

artículo científico publicado en 2015

Osteopontin is upregulated during in vivo demyelination and remyelination and enhances myelin formation in vitro

artículo científico publicado en 2004

Pivotal involvement of Fcgamma receptor IIA in the neutralization of lipopolysaccharide signaling via a potent novel anti-TLR4 monoclonal antibody 15C1.

artículo científico publicado en 2007

Rapid, simple and high yield production of recombinant proteins in mammalian cells using a versatile episomal system.

artículo científico publicado en 2010

Robust Antibody-Antigen Complexes Prediction Generated by Combining Sequence Analyses, Mutagenesis, In Vitro Evolution, X-ray Crystallography and In Silico Docking

artículo científico publicado en 2015

Robust recombinant FcRn production in mammalian cells enabling oriented immobilization for IgG binding studies

artículo científico publicado en 2011

Selective Blockade of the Ubiquitous Checkpoint Receptor CD47 Is Enabled by Dual-Targeting Bispecific Antibodies.

artículo científico publicado en 2017

Selective antibody intervention of Toll-like receptor 4 activation through Fc γ receptor tethering

artículo científico publicado en 2014

Short-term treatment with anti-CD3 antibody reduces the development and progression of atherosclerosis in mice

artículo científico publicado en 2006

Spatiotemporal expression of endogenous TLR4 ligands leads to inflammation and bone erosion in mouse collagen-induced arthritis

artículo científico publicado en 2016

TLR4/MD-2 monoclonal antibody therapy affords protection in experimental models of septic shock

artículo científico publicado en 2007

The 16th International Conference on Lymphatic Tissues and Germinal Centers in Immune Responses

scientific article published on 01 September 2009

Therapeutic Effects of Treatment with Anti-TLR2 and Anti-TLR4 Monoclonal Antibodies in Polymicrobial Sepsis

artículo científico publicado en 2015

Transferring the characteristics of naturally occurring and biased antibody repertoires to human antibody libraries by trapping CDRH3 sequences

artículo científico publicado en 2012

Lista de obras de

3D and 4D imaging of immune cells in vitro and in vivo

A homogeneous 384-well high-throughput binding assay for a TNF receptor using alphascreen technology

A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis

A specific anti-citrullinated protein antibody profile identifies a group of rheumatoid arthritis patients with a toll-like receptor 4-mediated disease

Antibody Neutralization of CXCL10 in Vivo Is Dependent on Binding to Free and Not Endothelial-bound Chemokine: IMPLICATIONS FOR THE DESIGN OF A NEW GENERATION OF ANTI-CHEMOKINE THERAPEUTIC ANTIBODIES.

CC chemokine CCL5 plays a central role impacting infarct size and post-infarction heart failure in mice

Characterization of a surrogate murine antibody to model anti-human CD3 therapies

Chemokines derived from soluble fusion proteins expressed in Escherichia coli are biologically active

Co-engaging CD47 and CD19 with a bispecific antibody abrogates B-cell receptor/CD19 association leading to impaired B-cell proliferation

Combination therapies in the context of anti-CD3 antibodies for the treatment of autoimmune diseases

Comparing CDRH3 diversity captured from secondary lymphoid organs for the generation of recombinant human antibodies

Constitutive activation of epithelial TLR4 augments inflammatory responses to mucosal injury and drives colitis-associated tumorigenesis

De novo isolation of antibodies with pH-dependent binding properties

Deep sequencing of phage display libraries to support antibody discovery

Deriving a germinal center lymphocyte migration model from two-photon data

Dual display: phage selection driven by co-engagement of two targets by two different antibody fragments

Effect of Toll-like receptor 4 blockade on pulmonary inflammation caused by mechanical ventilation and bacterial endotoxin

Enhancement of islet engraftment and achievement of long-term islet allograft survival by Toll-like receptor 4 blockade.

Epitope-dependent inhibition of T cell activation by the Ea transgene: an explanation for transgene-mediated protection from murine lupus

Exploiting light chains for the scalable generation and platform purification of native human bispecific IgG.

Germinal center B cells govern their own fate via antibody feedback

IL-17F co-expression improves cell growth characteristics and enhances recombinant protein production during CHO cell line engineering

Inhibition of airway inflammation by amino-terminally modified RANTES/CC chemokine ligand 5 analogues is not mediated through CCR3.

Interferon gamma (IFNg) production is associated to disease parameters in TLR9-induced secondary hemophagocytic lymphohistiocytosis (sHLH) in mice.

Long‐term amelioration of established collagen‐induced arthritis achieved with short‐term therapy combining anti‐CD3 and anti–tumor necrosis factor treatments ⬇️

Maximizing the potency of an anti-TLR4 monoclonal antibody by exploiting proximity to Fcγ receptors

Neutralization of IFNgamma defeats haemophagocytosis in LCMV-infected perforin- and Rab27a-deficient mice

Novel Insights into Interleukin 6 (IL-6) Cis- and Trans-signaling Pathways by Differentially Manipulating the Assembly of the IL-6 Signaling Complex

Osteopontin is upregulated during in vivo demyelination and remyelination and enhances myelin formation in vitro

Pivotal involvement of Fcgamma receptor IIA in the neutralization of lipopolysaccharide signaling via a potent novel anti-TLR4 monoclonal antibody 15C1.

Rapid, simple and high yield production of recombinant proteins in mammalian cells using a versatile episomal system.

Robust Antibody-Antigen Complexes Prediction Generated by Combining Sequence Analyses, Mutagenesis, In Vitro Evolution, X-ray Crystallography and In Silico Docking

Robust recombinant FcRn production in mammalian cells enabling oriented immobilization for IgG binding studies

Selective Blockade of the Ubiquitous Checkpoint Receptor CD47 Is Enabled by Dual-Targeting Bispecific Antibodies.

Selective antibody intervention of Toll-like receptor 4 activation through Fc γ receptor tethering

Short-term treatment with anti-CD3 antibody reduces the development and progression of atherosclerosis in mice

Spatiotemporal expression of endogenous TLR4 ligands leads to inflammation and bone erosion in mouse collagen-induced arthritis

TLR4/MD-2 monoclonal antibody therapy affords protection in experimental models of septic shock

The 16th International Conference on Lymphatic Tissues and Germinal Centers in Immune Responses

Therapeutic Effects of Treatment with Anti-TLR2 and Anti-TLR4 Monoclonal Antibodies in Polymicrobial Sepsis

Transferring the characteristics of naturally occurring and biased antibody repertoires to human antibody libraries by trapping CDRH3 sequences