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A conditionally replicating SIV variant that can be used to study the mechanism of protection conferred by live attenuated SIV vaccines.

artículo científico publicado en 2011

Anti-retroviral innate immune responses in multiple lymphoid tissues elicited by protective live attenuated SIV vaccination.

artículo científico publicado en 2011

CD8+ lymphocytes do not mediate protection against acute superinfection 20 days after vaccination with a live attenuated simian immunodeficiency virus

artículo científico publicado en 2005

Conditionally-live attenuated SIV upregulates global T effector memory cell frequency under replication permissive conditions

artículo científico publicado en 2013

Detection, Quantification, and Characterisation of HIV/SIV

artículo científico publicado el 1 de enero de 2011

Diversity of TRIM5α and TRIMCyp sequences in cynomolgus macaques from different geographical origins.

artículo científico publicado en 2011

Early biodistribution and persistence of a protective live attenuated SIV vaccine elicits localised innate responses in multiple lymphoid tissues

artículo científico publicado en 2014

Early potent protection against heterologous SIVsmE660 challenge following live attenuated SIV vaccination in Mauritian cynomolgus macaques.

artículo científico publicado en 2011

Macaques infected long-term with attenuated simian immunodeficiency virus (SIVmac) remain resistant to wild-type challenge, despite declining cytotoxic T lymphocyte responses to an immunodominant epitope

artículo científico publicado en 2004

Natural variation of the nef gene in human immunodeficiency virus type 2 infections in Portugal.

artículo científico publicado en 2003

Neuropathology of wild-type and nef-attenuated T cell tropic simian immunodeficiency virus (SIVmac32H) and macrophage tropic neurovirulent SIVmac17E-Fr in cynomolgus macaques

artículo científico publicado en 2012

Occult replication of a conditionally-live attenuated SIV profoundly upregulates T effector memory cell frequency.

artículo científico publicado en 2011

Passive immunisation of convalescent human anti-Zika plasma protects against challenge with New World Zika virus in cynomolgus macaques

scientific article published on 15 September 2020

Potent autologous and heterologous neutralizing antibody responses occur in HIV-2 infection across a broad range of infection outcomes

artículo científico publicado en 2011

Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel

artículo científico publicado en 2008

Proceedings of the Frontiers of Retrovirology Conference 2016.

artículo científico publicado en 2016

Replication kinetics and persistence of a conditionally live attenuated SIV (SIVrtTA) in vivo confers protection against SIVmac239 wild-type challenge in a rhesus macaque model

artículo científico publicado en 2009

Replication kinetics and persistence of a conditionally live attenuated SIV (SIVrtTA) in vivo confers protection against homologous and heterologous wild-type challenge in macaques

Role of Occult and Post-acute Phase Replication in Protective Immunity Induced with a Novel Live Attenuated SIV Vaccine

artículo científico publicado en 2016

Undetectable plasma viral load predicts normal survival in HIV-2-infected people in a West African village

artículo científico publicado en 2010

Universal amplification, next-generation sequencing, and assembly of HIV-1 genomes

artículo científico publicado en 2012

Vaccination with live attenuated simian immunodeficiency virus causes dynamic changes in intestinal CD4+CCR5+ T cells

artículo científico publicado en 2011