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4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp

artículo científico publicado en 2020

Cocrystal structure of meningococcal factor H binding protein variant 3 reveals a new crossprotective epitope recognized by human mAb 1E6

artículo científico publicado en 2019

Crystal structures of human Fabs targeting the Bexsero meningococcal vaccine antigen NHBA

artículo científico publicado en 2017

Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen

artículo científico publicado en 2013

Exploiting chimeric human antibodies to characterize a protective epitope of Neisseria adhesin A, one of the Bexsero vaccine components

artículo científico publicado en 2015

Exploring host-pathogen interactions through genome wide protein microarray analysis

artículo científico publicado en 2016

Molecular Engineering of Ghfp, the Gonococcal Orthologue of Neisseria meningitidis Factor H Binding Protein

artículo científico publicado en 2015

Neisseria meningitidis factor H-binding protein bound to monoclonal antibody JAR5: implications for antibody synergy.

artículo científico publicado en 2016

Rational design of a meningococcal antigen inducing broad protective immunity

artículo científico publicado en 2011

Structural characterization of a cross-protective natural chimera of factor H binding protein from meningococcal serogroup B strain NL096

artículo científico publicado en 2022

Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody

artículo científico publicado en 2014

Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody

scientific article published in PLoS ONE

Synergic complement-mediated bactericidal activity of monoclonal antibodies with distinct specificity

artículo científico publicado en 2020

The factor H binding protein of Neisseria meningitidis interacts with xenosiderophores in vitro.

artículo científico publicado en 2012

Two cross-reactive monoclonal antibodies recognize overlapping epitopes on Neisseria meningitidis factor H binding protein but have different functional properties

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