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A three-dimensional tumor cell defect in activating autologous CTLs is associated with inefficient antigen presentation correlated with heat shock protein-70 down-regulation.

artículo científico publicado en 2003

AXL Targeting Overcomes Human Lung Cancer Cell Resistance to NK- and CTL-Mediated Cytotoxicity

artículo científico publicado en 2019

Acquisition of tumor cell phenotypic diversity along the EMT spectrum under hypoxic pressure: Consequences on susceptibility to cell-mediated cytotoxicity

artículo científico publicado en 2017

Alpha E beta 7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis

artículo científico publicado en 2007

Analysis of the mechanisms of human cytotoxic T lymphocyte response inhibition by NO.

artículo científico publicado en 2002

Antitumor cytotoxic T-lymphocyte response in human lung carcinoma: identification of a tumor-associated antigen.

artículo científico publicado en 2002

Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression.

artículo científico publicado en 2011

CD103 or LFA-1 Engagement at the Immune Synapse between Cytotoxic T Cells and Tumor Cells Promotes Maturation and Regulates T-cell Effector Functions

artículo científico publicado el 27 de noviembre de 2012

CD8+CD103+ tumor-infiltrating lymphocytes are tumor-specific tissue-resident memory T cells and a prognostic factor for survival in lung cancer patients

artículo científico publicado en 2015

Co-delivery of the NKT agonist α-galactosylceramide and tumor antigens to cross-priming dendritic cells breaks tolerance to self-antigens and promotes antitumor responses

artículo científico publicado en 2017

Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage

artículo científico publicado en 2020

Cutting Edge: NANOG Activates Autophagy under Hypoxic Stress by Binding to BNIP3L Promoter.

artículo científico publicado en 2017

Cytotoxic T lymphocytes directed against a tumor-specific mutated antigen display similar HLA tetramer binding but distinct functional avidity and tissue distribution.

artículo científico publicado en 2002

Different expression levels of the TAP peptide transporter lead to recognition of different antigenic peptides by tumor-specific CTL.

artículo científico publicado en 2011

Drug specific cytotoxic T-cells in the skin lesions of a patient with toxic epidermal necrolysis.

artículo científico publicado en 2002

EMT impairs breast carcinoma cell susceptibility to CTL-mediated lysis through autophagy induction

artículo científico publicado el 23 de abril de 2013

Editorial: Tissue Resident Memory T Cells

artículo científico publicado en 2019

Endothelial cells as key determinants of the tumor microenvironment: interaction with tumor cells, extracellular matrix and immune killer cells

scientific article published on January 2010

Engagement of CD160 receptor by HLA-C is a triggering mechanism used by circulating natural killer (NK) cells to mediate cytotoxicity.

artículo científico publicado en 2002

Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell-mediated lysis.

artículo científico publicado en 2013

Functional and molecular characterization of a KIR3DL2/p140 expressing tumor-specific cytotoxic T lymphocyte clone infiltrating a human lung carcinoma

artículo científico publicado en 2003

Gap junction communication between autologous endothelial and tumor cells induce cross-recognition and elimination by specific CTL.

artículo científico publicado en 2009

Generation of diverse mutated tumor antigen-specific cytotoxic T lymphocytes in a lung cancer patient with long survival

scientific article published on 01 September 2005

Granzyme B-activated p53 interacts with Bcl-2 to promote cytotoxic lymphocyte-mediated apoptosis.

artículo científico publicado en 2014

Human CD5 protects circulating tumor antigen-specific CTL from tumor-mediated activation-induced cell death

artículo científico publicado en 2007

Human preprocalcitonin self-antigen generates TAP-dependent and -independent epitopes triggering optimised T-cell responses toward immune-escaped tumours

artículo científico publicado en 2018

Hypoxia-dependent inhibition of tumor cell susceptibility to CTL-mediated lysis involves NANOG induction in target cells

artículo científico publicado en 2011

Hypoxia-induced autophagy: a new player in cancer immunotherapy?

artículo científico publicado en 2012

Hypoxia-inducible miR-210 regulates the susceptibility of tumor cells to lysis by cytotoxic T cells

artículo científico publicado en 2012

Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer

artículo científico publicado en 2015

Identification of target actin content and polymerization status as a mechanism of tumor resistance after cytolytic T lymphocyte pressure

artículo científico publicado en 2006

In situ sensory adaptation of tumor-infiltrating T lymphocytes to peptide-MHC levels elicits strong antitumor reactivity

artículo científico publicado en 2005

Intratumoral induction of CD103 triggers tumor-specific CTL function and CCR5-dependent T-cell retention

artículo científico publicado en 2009

Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors

artículo científico publicado en 2012

Minimal Engagement of CD103 on Cytotoxic T Lymphocytes with an E-Cadherin-Fc Molecule Triggers Lytic Granule Polarization via a Phospholipase Cγ–Dependent Pathway

artículo científico publicado el 11 de enero de 2011

Mutant alpha-actinin-4 promotes tumorigenicity and regulates cell motility of a human lung carcinoma

artículo científico publicado en 2004

NK cells infiltrating a MHC class I-deficient lung adenocarcinoma display impaired cytotoxic activity toward autologous tumor cells associated with altered NK cell-triggering receptors

artículo científico publicado en 2005

Paxillin Binding to the Cytoplasmic Domain of CD103 Promotes Cell Adhesion and Effector Functions for CD8+ Resident Memory T Cells in Tumors.

artículo científico publicado en 2017

Potentiation of NK cell-mediated cytotoxicity in human lung adenocarcinoma: role of NKG2D-dependent pathway

artículo científico publicado en 2008

Potentiation of a tumor cell susceptibility to autologous CTL killing by restoration of wild-type p53 function.

artículo científico publicado en 2003

Preprocalcitonin signal peptide generates a cytotoxic T lymphocyte-defined tumor epitope processed by a proteasome-independent pathway

artículo científico publicado en 2008

Recent Advances in Lung Cancer Immunotherapy: Input of T-Cell Epitopes Associated With Impaired Peptide Processing

artículo científico publicado en 2019

Recent Advances in Targeting CD8 T-Cell Immunity for More Effective Cancer Immunotherapy.

artículo científico publicado en 2018

Regulation of antitumour CD8 T-cell immunity and checkpoint blockade immunotherapy by Neuropilin-1

artículo científico publicado en 2019

Renal Cell Carcinoma Programmed Death-ligand 1, a New Direct Target of Hypoxia-inducible Factor-2 Alpha, is Regulated by von Hippel-Lindau Gene Mutation Status

artículo científico publicado en 2015

Rescue of Tumor-Infiltrating Lymphocytes from Activation-Induced Cell Death Enhances the Antitumor CTL Response in CD5-Deficient Mice

artículo científico publicado el 27 de mayo de 2011

Resident memory T cells, critical components in tumor immunology

artículo científico publicado en 2018

Resistance of tumor cells to cytolytic T lymphocytes involves Rho-GTPases and focal adhesion kinase activation.

artículo científico publicado en 2008

Role of chemokines and chemokine receptors in shaping the effector phase of the antitumor immune response.

artículo científico

Role of p53 in the sensitization of tumor cells to apoptotic cell death

scientific article published on 01 May 2002

Smad and NFAT pathways cooperate to induce CD103 expression in human CD8 T lymphocytes

scientific article published on 29 January 2014

Synaptic release of CCL5 storage vesicles triggers CXCR4 surface expression promoting CTL migration in response to CXCL12.

artículo científico publicado en 2014

T-cell modulatory properties of CD5 and its role in antitumor immune responses

artículo científico publicado el 1 de enero de 2013

TAP expression level in tumor cells defines the nature and processing of MHC class I peptides for recognition by tumor-specific cytotoxic T lymphocytes

artículo científico

TGFβ Signaling Intersects with CD103 Integrin Signaling to Promote T-Lymphocyte Accumulation and Antitumor Activity in the Lung Tumor Microenvironment.

artículo científico publicado en 2016

The Emerging Role of CD8 Tissue Resident Memory T (T) Cells in Antitumor Immunity: A Unique Functional Contribution of the CD103 Integrin

scientific article published on 15 August 2018

The cooperative induction of hypoxia-inducible factor-1 alpha and STAT3 during hypoxia induced an impairment of tumor susceptibility to CTL-mediated cell lysis.

artículo científico publicado en 2009

The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200.

artículo científico publicado en 2017

The multifaceted role of autophagy in tumor evasion from immune surveillance

artículo científico publicado en 2016

Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance

artículo científico publicado en 2010

Tumor resistance to specific lysis: a major hurdle for successful immunotherapy of cancer

artículo científico publicado en 2008

Tumor-infiltrating CD4+ T lymphocytes express APO2 ligand (APO2L)/TRAIL upon specific stimulation with autologous lung carcinoma cells: role of IFN-alpha on APO2L/TRAIL expression and -mediated cytotoxicity

scientific article published on 01 July 2002

Tumor/cytotoxic effector cross-talk in the control of tumor susceptibility to lysis

artículo científico publicado en 2003

Wild-type p53 induced sensitization of mutant p53 TNF-resistant cells: role of caspase-8 and mitochondria

artículo científico publicado en 2002

[Immune response and cancer]

scientific article published on 01 January 2008

[Immunotherapy of cancer: promise and reality]

scientific article published on 01 August 2006

p53 potentiation of tumor cell susceptibility to CTL involves Fas and mitochondrial pathways.

artículo científico publicado en 2005

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016